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Bioinformatics News 07/2010

Rubicon Genomics' PicoPlex Linear Amplification Technology Enables Successful International Clinical Genetic Study Of ...
Rubicon Genomics announced that its PicoPlex linear whole genome amplification (WGA) technology was proven to be effective in an independent clinical study organized by the European Society for Human Reproduction and Embryology (ESHRE). At a press conference during its 26th Annual Meeting in Rome, ESHRE reported the success of its "groundbreaking proof of principle study" showing that a new ...

Ariadne to Contribute Bioinformatics Tools for $9.4M EU Biomarker-Discovery Project
Ariadne Genomics said this week that it will provide bioinformatics resources for a European project that aims to identify non-invasive biomarkers for monitoring neuromuscular diseases, with a particular focus on Duchenne and Becker muscular dystrophies and collagen VI myopathies.

Eagle Genomics to Supply Bioinformatics Services to UK's One Nucleus Members
Eagle Genomics said this week that it has signed a support supplier agreement with One Nucleus, a UK-based life science membership organization that will provide One Nucleus members with access to its bioinformatics services at discounted rates.

BIOINFORMATICS BRIEFS
Just months after Pacific Northwest National Laboratory announced plans to install an 8.3-teraflop Hewlett-Packard Linux-based supercomputer to support its biological research projects, Lawrence Livermore National Lab said last week that it plans to top its DOE sibling with a 9.2-teraflop Evolocity cluster from Linux Networx.

Press Release
Aushon BioSystems, Inc., a leading provider of advanced microarray instrumentation and laboratory services for biomarker discovery, development and analysis, has launched new Human multiplex biomarker panels for the quantification of eight biomarkers related to drug-induced kidney damage, or nephrotoxicity.

In Brief This Week: Cofactor Genomics, Knome; Rosetta Genomics; Eagle Genomics; BioServe, UMass
NEW YORK (GenomeWeb News) Cofactor Genomics said this week that it has installed an Applied Biosystems SOLiD 4 sequencer and plans to use the instrument to sequence the genome of British heavy metal legend Ozzy Osbourne.

Genomics Gaining Favor for Food Safety Applications
NEW YORK (GenomeWeb News) As part of their ongoing effort to curtail foodborne infections, academic researchers and public health agencies are increasingly exploring the use of genomics-based approaches to complement existing food safety and surveillance methods.

Grant will boost MUs ability in genetic code research
The University of Missouri is receiving advanced computing technology that will allow researchers to better understand the genetic code of humans, plants and animals. A grant from IBM valued at between $175,000 and $200,000 will supply the university with more storage space and more powerful processors through its four-campus Bioinformatics Consortium. More than 70 additional central ...

Moving Away From Microarrays
In the burgeoning field of transcriptomics, it's no surprise that those who maintain an if-it-ain't-broke-don't-fix-it mentality are being outperformed by investigators willing to embrace the power and challenges of nascent, albeit imperfect, technologies.

Research and Markets: RNAi - Technologies, Markets and Companies
DUBLIN----Research and Markets has announced the addition of Jain PharmaBiotech's new report "RNAi - Technologies, Markets and Companies" to their offering.

Research and Markets: Cytogenetics - Technologies, Markets and Companies
DUBLIN----Research and Markets has announced the addition of Jain PharmaBiotech's new report "Cytogenetics - Technologies, Markets and Companies" to their offering.

Brain diseases linked to nerve cell junction defects
More than 135 brain diseases including autism, chronic pain, schizophrenia and dementia are linked to defects in proteins in the junctions between nerve cells, scientists have found.

Scientists find blood protein link to Alzheimer's
By Kate Kelland

Chromosomal abnormality found for inherited clubfoot
Although clubfoot is one of the most common congenital birth defects, few genetic causes have been found. Now, researchers have found what they believe to be the most common cause of inherited clubfoot yet discovered.

ABRF's Microarray Research Group Completes Testing for Five CGH Platforms, Preps Paper
PHILADELPHIA The Association of Biomolecular Resource Facilities Microarray Research Group has completed a project that tests the ability of five different array platforms to detect genetic changes in a human leukemia sample using comparative genomic hybridization, and will soon submit the results of the study for publication and release the data to the public, according to a MARG member.

Blood protein linked to Alzheimer's
A new medical research has revealed that high levels of clusterin protein in blood appear to be associated with the development of Alzheimer's disease.

TGen finds protein inhibitor revives chemotherapy for ovarian patients
( The Translational Genomics Research Institute ) Investigators at the Translational Genomics Research Institute have discovered a way that may help ovarian cancer patients who no longer respond to conventional chemotherapy.

Ocimum offers new solutions in miRNA microarray technology
Hyderabad, Jul 6 : Ocimum Biosolutions, a global integrated genomics company, today announced that it now offers cutting edge solutions using miRNA microarray technology.

Protein Inhibitor Revives Chemotherapy For Ovarian Patients: TGen Findings
Investigators at the Translational Genomics Research Institute (TGen) have discovered a way that may help ovarian cancer patients who no longer respond to conventional chemotherapy. A scientific paper that will be published in the September issue of the journal Gynecologic Oncology describes how the inhibition of a protein, CHEK1, may be an effective element to incorporate into therapies for ...

Scientists Find Blood Protein Link to Alzheimer's
High levels of a blood protein called clusterin are linked to the development of Alzheimer's disease, scientists said on Monday a finding which could pave the way for doctors to detect the disease before it takes hold.

Research and Markets: Proteomics - Technologies, Markets and Companies
DUBLIN----Research and Markets has announced the addition of Jain PharmaBiotech's new report "Proteomics - Technologies, Markets and Companies" to their offering.

Rosetta Genomics and Collaborators Demonstrate MicroRNAs Accurately Sub-Classify Renal Tumors
REHOVOT, Israel & PHILADELPHIA----Rosetta Genomics, Ltd. , a leading developer and provider of microRNA-based molecular diagnostics, announces that a peer-reviewed article entitled Accurate Molecular Classification of Renal Tumors Using MicroRNA Expression has been published in the online version of The Journal of Molecular Diagnostics.

Scientists find blood protein link to Alzheimer's
(Reuters) - High levels of a blood protein called clusterin are linked to the development of Alzheimer's disease, scientists said on Monday -- a finding which could pave the way for doctors to detect the disease before it takes hold. Researchers from the Institute of Psychiatry at King's College London said that while doctors are around 5 years away from being able to use the discovery for a ...

Research and Markets: Animal Biotechnology - Technologies, Markets and Companies
DUBLIN----Research and Markets has announced the addition of Jain PharmaBiotech's new report "Animal Biotechnology - Technologies, Markets and Companies" to their offering.

Reportlinker Adds Innovations in Combating Infectious Diseases: Opportunities in Therapeutics and Diagnostics Through ...
Reportlinker.com announces that a new market research report is available in its catalogue:

ESHRE study shows new PGS method can predict chromosomal abnormalities
( European Society of Human Reproduction and Embryology ) The efficacy of preimplantation genetic screening (PGS) has been one of the most hotly disputed subjects in assisted reproduction over the past few years. The European Society of Human Reproduction and Embryology PGS Task Force has now shown, in its groundbreaking proof of principle study, that screening of polar bodies (small cells that ...

Study shows new PGS method can predict chromosomal abnormalities
Scientists at the University of Bonn and at the SISMER centre in Bologna used a new micro-array technology that screens all chromosomes in one cell within 12 hours, allowing for fresh transfer of the egg into the female patient. They could identify the chromosomal status of the eggs in 89 % of all polar bodies analysed, Prof. Joep Geraedts told the 26th Annual Meeting of the European Society of ...

QIAGEN Announces CE Marking of its careHPV Test for Developing Countries
MONTREAL, July 6 /PRNewswire-FirstCall/ -- QIAGEN (Nasdaq: QGEN; Frankfurt, Prime Standard: QIA) has completed European certification of its careHPV(TM) Test to bring human papillomavirus (HPV) testing to public-health programs in low-resource, developing countries, the company announced today at the International Papillomavirus Conference in Montreal, Canada. The CE conformity marking ...

U of Missouri, IBM to Build Genomics Cloud Computing Environment
The University of Missouri and IBM said last week that they will develop what they call a first-of-a-kind cloud computing environment for use in genomics research as well as personalized medicine.

Q&A: U of Maryland's Steven Salzberg on Assembling Genomes with Short-Read Sequence Data
Steven Salzberg developed one of the first computational gene-finding programs, Glimmer, to assess microbial DNA, as well as gene-prediction programs that have been used to analyze hundreds of bacterial, viral, plant, and animal genomes.

New TGen technology reduces storage needs and costs for genomic data
( The Translational Genomics Research Institute ) A new computer data compression technique called Genomic SQueeZ, developed by the Translational Genomics Research Institute, will allow genetic researchers and others to store, analyze and share massive volumes of data in less space and at lower cost.

New Protocols Offer Guidance on Optimizing Sequencing Experiments to Assess CNVs, Detect Transcripts
As next-generation sequencing continues to become faster and cheaper, researchers are using the technology for an increasingly wider range of applications, but for many tasks, such as assessing structural variation, there is no standard method for how to best capture all the relevant information in a genome.

New retrieval method makes studying cancer proteins easier
A Purdue University researcher can better retrieve specific proteins needed to study how cancer cells form by using a newly developed technique and synthetic nanopolymer.

New technology reduces storage needs and costs for genomic data
A new computer data compression technique called Genomic SQueeZ (G-SQZ), developed by the Translational Genomics Research Institute (TGen), will allow genetic researchers and others to store, analyze and share massive volumes of data in less space and at lower cost.

TGen Releases Genomic Data Compression Tool
Researchers at the Translational Genomics Research Institute (TGen) have released a new genomic database compression technique called Genomic SQueeZ (G-SQZ) that might just be a contender to compete with Occarina Network's compression solution.

TGen Launches New Genomic Data Compression Technique
The Translational Genomics Research Institute has launched a data-compression technique that it says can compress genomic data by as much as 80 percent and will allow researchers to store, analyze, and share large quantities of sequence data using less space and at lower costs.

NIH Funds Cedars-Sinai's Cardiac Arrest Studies
NEW YORK (GenomeWeb News) Researchers at the Cedars-Sinai Heart Institute will use a $1.7 million grant from the National Heart, Lung, and Blood Institute to use electrophysiology, genomics, and data from a large heart study to develop a system to predict which individuals may experience sudden cardiac arrest.

IP Roundup
Affymetrix has received US Patent No. 7,745,178, "Complexity management of genomic DNA." The patent describes non-gel-based methods for amplifying a subset of the sequences in a sample in order to reduce nucleic acid sample complexity.

New Product Watch
Ocimum Biosolutions this week introduced a range of microRNA microarray kits and assays including human, mouse, rat, and other systems on its OciChip platform.

Amazon Sees the Future of Biology in the Cloud
How Amazon Web Services is helping life sciences companies.

New technology reduces storage needs and costs for genomic data
A new computer data compression technique called Genomic SQueeZ will allow genetic researchers and others to store, analyze and share massive volumes of data in less space and at lower cost.

IP Update
The invention, the patent's abstract states, comprises "a method for the identification of genes that are essential for the maintenance of specific cell phenotypes. The method includes the initial step of identifying a cell type with a phenotype of interest.

Retrieval method makes cancer study easier
WEST LAFAYETTE, Ind., July 6 (UPI) -- A new retrieval method makes studying cancer proteins easier, a researcher at Purdue University in West Lafayette, Ind., said. Purdue University - West Lafayette Indiana - WEST LAFAYETTE - Cancer - United States

Tgen develops data-storage software
TGen researchers develop a new computer software that allows scientists to save data-storage space. TGen plans to share the technology with other non-profits and academic researchers and sell the technology to biotechnology companies.

Sylentis Completes Phase I Trial with SYL040012 to Treat Elevated Intraocular Pressure and Glaucoma
MADRID, July 6 /PRNewswire/ -- Sylentis, a biopharmaceutical subsidiary of Grupo Zeltia (MC: ZEL) and a pioneer in the research and development of new drugs based on gene silencing (interference RNA, RNAi), has completed Phase Ia of its first clinical trial with SYL040012 in the form of ophthalmic drops to treat elevated intraocular pressure and glaucoma. This is the first product based on RNAi ...

IBM awards MU new bank of computers
IBM has awarded the University of Missouri-Columbia a cluster of computers to help analyze genome research on plants and animals. COLUMBIA, Mo. (AP) -- IBM has awarded the University of Missouri-Columbia a cluster of computers to help analyze genome research on plants and animals.

TGen develops G-SQZ technique for genomic data processing
A new computer data compression technique called Genomic SQueeZ, developed by the Translational Genomics Research Institute, will allow genetic researchers and others to store, analyze and share massive volumes of data in less space and at lower cost.

OSU center singled out for state praise
Ohio State University was one of six universities named as a "center of excellence" in advanced transportation and aerospace, the Ohio Board of Regents said yesterday.

Affymetrix Announces Preliminary Revenue for Second Quarter 2010
SANTA CLARA, Calif.----Affymetrix, Inc. today reported that based on preliminary financial data, the Company expects total revenue for the second quarter of 2010 to be in the range of $71-72 million, as compared to the Companys previous guidance in the range of $80-82 million.

Biomarkers in Late Stage Clinical Trials: Applications, opportunities and activities of leading players
Reportlinker.com announces that a new market research report is available in its catalogue:


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