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Bioinformatics News 04/2010 (Page 5)

Agendia and Ferrer inCode Expand MammaPrint(R) Distribution Agreement to Latin America
Agendia, a world leader in molecular cancer diagnostics, announced today it has closed an agreement with Ferrer inCode for the commercialization of Agendia's FDA-cleared breast cancer recurrence test MammaPrint in Latin America.

Olive Oil May Be Key to Mediterranean Diet's Benefits
TUESDAY, April 20 (HealthDay News) -- The heart-healthy effects of the famous "Mediterranean diet" may have something to do with components of virgin olive oil that repress genes that promote inflammation, a new study reports.

Agendia and Ferrer inCode Expand MammaPrint(R) Distribution Agreement to Latin America
HUNTINGTON BEACH, California and AMSTERDAM, April 20, 2010 (ots/PRNewswire) -- Agendia, a world leader in molecular cancer diagnostics, announced today it has closed an agreement with Ferrer inCode for the commercialization of Agendia's ...

PerkinElmer Inks Deal
PerkinElmer Inc. agreed to acquire Signature Genomic Laboratories LLC, a diagnostic genetic testing company.

Spirit of ovarian cancer advocate keeps fundraising drive on track
( The Translational Genomics Research Institute ) The Anne Rita Monahan Foundation recently presented $15,000 for ovarian cancer research to the Translational Genomics Research Institute.

Molecular mechanism underlying natural taurine protection against hepatic fibrosis
( World Journal of Gastroenterology ) A research team from China investigated the global protein expression changes in hepatic stellate cells affected by taurine using ultra-performance liquid chromatography-electrospray ionization-tandem mass spectrometry platform. Their results showed that natural taurine can promote HSC apoptosis so as to inhibit hepatic fibrosis.

'Mediterranean Diet' And Genetic Basis For Health Benefits
Eating a diet rich in the phenolic components of virgin olive oil represses several pro-inflammatory genes. Researchers writing in the open access journal BMC Genomics suggest that this partly explains the reduced risk of cardiovascular disease seen in people who eat a 'Mediterranean diet'...

Ferrer to be Agendia's Latin America Distributor
NEW YORK (GenomeWeb News) Agendia said today that it has hired Ferrer inCode to distribute its MammaPrint breast cancer diagnostic test in Latin America.

IP Roundup
Agilent Technologies has received US Patent No. 7,700,289, "Method for labeling RNA." The patent describes a method of labeling RNA in a sample by: a) contacting a sample of RNAs with calf intestinal alkaline phosphatase under conditions and for a time sufficient to result in dephosphorylated RNA; b) mixing the dephosphorylated RNA with dimethyl sulfoxide; and c) contacting the solution with an ...

PerkinElmer to Acquire Cyto Array Firm Signature Genomic Labs for $90M to Bolster Testing Services
This article has been updated from a version posted April 15 to include comments from PerkinElmer. PerkinElmer has reached an agreement to buy Signature Genomic Laboratories.

How Genetics Affect Business
Genomics Law Report's Allain Andry says advances in genetics ripple out through the business world and through new laws, regulations, and uncertainty over patents affect almost all businesses in some fashion.

Agendia and Ferrer inCode Expand MammaPrint(R) Distribution Agreement to Latin America
HUNTINGTON BEACH, California and AMSTERDAM, April 20, 2010 /PRNewswire/ -- Agendia, a world leader in molecular cancer diagnostics, announced today it has closed an agreement with Ferrer inCode for the commercialization of Agendia's FDA-cleared breast cancer recurrence test MammaPrint in Latin America. For the successful commercialization of MammaPrint, Ferrer inCode will leverage the ...

Molecular Mechanism Underlying Natural Taurine Protection Against Hepatic Fibrosis
Hepatic fibrosis (HF) occurs in most types of chronic liver diseases and approximately 25%-40% of HF cases may ultimately progress to hepatic cirrhosis.

DNAnexus Aims to Alleviate Next-Gen Sequence Analysis Headache with Cloud-based Service
As users of high-throughput sequencing platforms continue to struggle with managing and analyzing large amounts of sequence data, DNAnexus, a new Stanford University spinout, promises relief.

CombiMatrix, Restructuring and Seeking New CEO, Refocuses on Diagnostics
CombiMatrix will restructure its operations by increasing its focus on its diagnostics services business and reducing its cash burn by roughly half, the firm said this week.

Researchers Use CE Sequencing to ID Novel Insertions and Fill Gaps in Human Reference Genome
Researchers from the University of Washington recently characterized human genome sequences and copy number polymorphic insertions that have been missing from the human reference genome.

GenomeQuest Offers New Product for Pharma to Integrate Whole Genome Studies into Private Research
Research Organizations Can Massively Expand Sample Sizes at Virtually No Cost and Accelerate Transition to Molecular-based Personalized Medicine

Arrayit Posts Flat FY '09 Revenues, Rolls Out Antibody Screening Arrays, New Instruments
Arrayit last week said that it has made "significant progress" in its efforts to develop and launch pre-symptomatic tests, expand its microarray services, and introduce new instruments.

NanoString Unveils miRNA Expression Assays Based on Digital Barcode Tech
NanoString Technologie s this week unveiled a new product for microRNA analysis that uses multiplex digital barcode technology to profile the human miRNA transcriptome in a single tube.

Genetic Markers in Jeopardy
Despite the silver bullet that genomics often promises to be for advancing disease prevention and treatment, sometimes discovering its limitations can be just as important as exploring its potential.

Roche NimbleGen Q1 Array Sales Up 40 Percent on Sequence-Capture Demand
Sales of Roche NimbleGen microarrays rose nearly 40 percent in the first quarter of 2010, Roche said last week. A company spokesperson attributed the growth to "strong demand" for the firm's sequence capture, DNA methylation, and cytogenetic arrays.

Q&A: Amgen's Alex Parker on Next-Gen Sequencing to Study Patient Response in Clinical Trials
Name : Alex Parker Position : Principal scientist, Molecular Sciences group, Amgen, Cambridge, Mass. As a principal scientist in the Molecular Sciences group at Amgen's Cambridge, Mass., site, Alex Parker has been using 454's sequencing platform for more than a year, primarily to look for mutations in tumor samples from patients enrolled in Amgen's clinical trials.

Baby Sling Recall Fallout: Whats the Best Way to Tote an Infant?
A recall has parents wondering how to keep babies closeand safe.

U of Chicago Teams with Field Museum on Emerging Pathogen Study
NEW YORK (GenomeWeb News) The University of Chicagos Institute for Genomics and Systems Biology will partner with the Field Museum to study the evolution of species-switching parasites and pathogens that cause diseases such as bird flu, malaria, and AIDS.

Multiple Myeloma Research Consortium (MMRC) Genomics Initiative Provides First In-depth Look at Multiple Myeloma Genome
NORWALK, Conn.----An analysis of 38 myeloma tumor genomes surveyed through extensive next-generation sequencing by the Broad Institute has revealed intriguing recurrent mutations that point to important cellular pathways which contribute to multiple myeloma.

Research in infectious diseases and immunology receives shot in the arm with fresh funding
( Agency for Science, Technology and Research (A*STAR), Singapore ) Twelve research projects on infectious diseases and immunology have been awarded grants by A*STAR's Biomedical Research Council and Singapore Immunology Network this year. Led by researchers from local universities, research institutes and hospitals, these projects account for over one-third of the $23 million in grants from ...

2 Elmira-area students win merit scholarships
One student from Horseheads and another from Painted Post have been named in the first group of winners in the 55th annual National Merit Scholarship Program.

Research insider: Maternal mortality declining, wildfires on the rise and new UW rankings
This column keeps track of the UWs scientific community and the student and faculty research that takes place here each week.

UC Merced Connect: Reaching out to students with science
Michelle Obama , during her UC Merced commencement speech last year, told of growing up just a few mi

Tea for Teal event raises $15,000 for TGen ovarian cancer research
The Anne Rita Monahan Foundation recently presented $15,000 for ovarian cancer research to the Translational Genomics Research Institute (TGen).

MMRC Multiple Myeloma Genomics Initiative presented at AACR 2010
An analysis of 38 myeloma tumor genomes surveyed through extensive next-generation sequencing by the Broad Institute has revealed intriguing recurrent mutations that point to important cellular pathways which contribute to multiple myeloma. These data were revealed during an oral presentation entitled "First Impressions of the Multiple Myeloma Genome" by Todd R. Golub, MD, Director of the Cancer ...

Second sequenced family emerges from anonymity [Genetic Future]
It's a big week for family genomics. I wrote a couple of days ago about the West family, all four members of which recently had their entire genomes sequenced by Illumina. Now an article in the Salt Lake Tribune reveals the identity of yet another four-person nuclear family with complete genome sequences: the wife and two step-children of Utah geneticist Lynn Jorde , as well as the children's ...

A*STAR's BMRC and SIgN award grants for twelve research projects on infectious diseases and immunology
Twelve research projects on infectious diseases and immunology have been awarded grants by A*STAR's Biomedical Research Council (BMRC) and Singapore Immunology Network (SIgN) this year.

Spirit Of Ovarian Cancer Advocate Keeps Fundraising Drive On Track
The Anne Rita Monahan Foundation recently presented $15,000 for ovarian cancer research to the Translational Genomics Research Institute (TGen). That amount brings to $50,000 the total amount raised by the organization named for Anne Rita Monahan, a Phoenix woman who used her initials to encourage women to "ARM yourself against ovarian cancer." Funds were raised at the 2nd annual Tea for TEAL ...

Study helps understand molecular mechanism underlying taurine's protection against hepatic fibrosis
Hepatic fibrosis (HF) occurs in most types of chronic liver diseases and approximately 25%-40% of HF cases may ultimately progress to hepatic cirrhosis. Hepatic stellate cells (HSCs) contribute significantly to the occurrence of HF and the activation of HSC is the key issue in the pathogenesis of HF. Taurine is a kind of important anti-injury substance in the body.

Research and Markets: Biomarkers in Late Stage Clinical Trials: Applications, Opportunities and Activities of Leading ...
DUBLIN----Research and Markets has announced the addition of the "Biomarkers in Late Stage Clinical Trials: Applications, Opportunities and Activities of Leading Players" report to their offering.

Critical Biologics To Use Scarab Genomics' Clean Genome E. Coli To Produce Recombinant Human Plasma Gelsolin
Critical Biologics Corporation (CBC) and Scarab Genomics announced today a strategic agreement to substantially increase the manufacturing yield of CBC's lead therapeutic protein candidate, Solinex, an intravenous formulation of recombinant human plasma gelsolin (rhu-pGSN)...


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