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Bioinformatics News 03/2010 (Page 7)

Celebrity genomics without the Y chromosome: Glenn Close has her genome sequenced [Genetic Future] (ScienceBlogs)
Zoe McDougall from Oxford Nanopore points me to a press release from Illumina announcing a new era of celebrity genomics: Illumina, Inc. (NASDAQ:ILMN) today announced that it has sequenced the DNA of American actress Glenn Close, the first publicly named female to have her DNA sequenced to full coverage. The service was completed in Illumina's CLIA certified and CAP accredited laboratory ...

BioMicro Sells Microarray Assets to Roche (GenomeWeb News)
NEW YORK (GenomeWeb News) – Roche Diagnostics said today that it has struck a deal with Salt Lake City-based BioMicro Systems to buy all of the products associated with the Roche NimbleGen microarray workflow.

Rounding Out NimbleGen Workflow, Roche Acquires BioMicro Hyb Station, Mixers (GenomeWeb News)
Roche Diagnostics this week announced a deal with Salt Lake City-based BioMicro Systems to buy all of BioMicro's products associated with the Roche NimbleGen microarray workflow.

NSF Tries to Lure Minority Students to Science (GenomeWeb News)
President Obama's 2011 budget calls for the elimination of three National Science Foundation programs , according to Paul Basken of the Chronicle for Higher Education : the Historically Black Colleges and Universities Undergraduate Program, the Louis Stokes Alliances for Minority Participation, and the Tribal Colleges and Universities Program.

Favorable Figures (GenomeWeb News)
A trio of researchers from the American Cancer Society report their analysis of trends in age-standardized death rates for cancer in the US between 1970 and 2006. Their findings, published in PLoS ONE this week, suggest a net decline of 21 and 11 percent in the all-cancer death rates for men since 1970 and 1990, respectively.

LifeSciences BC Announces Recipients of the 2010 LifeSciences British Columbia Awards (Business Wire via Yahoo! Finance)
VANCOUVER, British Columbia----LifeSciences British Columbia today announced the recipients of the 2010 LifeSciences British Columbia Awards. They are:

Complete genomics finds its first diseases (New Scientist)
Whole-genome sequencing has found its first disease-causing mutations – but will it illuminate our genetic "dark matter", asks Ewen Callaway

New imaging technology brings trace chemicals into focus (w/ Video) (PhysOrg)
Arizona State Univeristy scientist N.J. Tao and his colleagues at the Biodesign Institute have hit on a new, versatile method to significantly improve the detection of trace chemicals important in such areas as national security, human health and the environment.

Effort aims to spike breast cancer with new approach (EurekAlert!)
( The Translational Genomics Research Institute ) Many women live with breast cancer that does not respond to standard medical treatment, a condition that researchers at the Virginia G. Piper Cancer Center at Scottsdale Healthcare want to change by aggressively targeting specific genes.

Effort Aims to Spike Breast Cancer With New Approach (redOrbit)
Virginia G.

NIH to Fund Collaborative Genomics, Behavioral Science in Animals (GenomeWeb News)
NEW YORK (GenomeWeb News) – The National Institutes of Health aims to support collaborative studies that use genomics in behavioral science, and plans to fund partnerships between multidisciplinary scientists using animal models, the agency announced this week.

Effects of lifestyle and exposures are mirrored in blood gene expression (PhysOrg)
A study by Norwegian and French researchers hopes to provide new understanding of how blood cells adjust gene expression in response to various clinical, biochemical and pathological conditions. The Norwegian Woman and Cancer (NOWAC) postgenome study, published March 12 in the open-access journal PLoS Genetics, highlights numerous blood gene sets affected by one's physical condition, lifestyle ...

Washington U. to expand data center for genomics (The Springfield News-Leader)
ST. LOUIS (AP) — A $14.3 million federal grant will help Washington University in St. Louis expand a data center used to identify the genetic origins of cancer.

Effects of lifestyle and exposures are mirrored in blood gene expression (EurekAlert!)
A study by Norwegian and French researchers hopes to provide new understanding of how blood cells adjust gene expression in response to various clinical, biochemical and pathological conditions. The Norwegian Woman and Cancer postgenome study, published March 12 in the open-access journal PLoS Genetics, highlights numerous blood gene sets affected by one's physical condition, lifestyle factors ...

W3C Group Plans Ontology for Translational Medicine to Help Bridge Drug Discovery Phases (GenomeWeb News)
The World Wide Web Consortium's Health Care and Life Sciences Interest Group and members of the National Center for Biomedical Ontology are wrapping up work on the first version of a "patient-centric" ontology for translational medicine.

USPTO Publishes Six RNAi-Related Patent Applications (GenomeWeb News)
The invention, the patent application’s abstract states, “relates to methods and genetic constructs for the control of expression of enzymes involved in lignin biosynthesis in plants.

OGT Gears Up to Launch New ChIP-on-Chip Line (GenomeWeb News)
Oxford Gene Technology next year plans to expand significantly its prokaryotic ChIP-on-chip line, to continue developing a syndrome array for array CGH applications, and to develop relationships with Japanese partners with an eye toward bringing its chips to European and North American markets, according to a company official.

Keeping the Balance (GenomeWeb News)
Tunisia Riley at Under the Microscope compiled a list of family-friendly companies in science, technology and health . She says that each of the companies on her list "have one or more of the following: a high percentage of women employees, good paid maternity/paternity leave, on-site childcare and a proven commitment to a work-life balance for their employees."

Hey, Bacteria: Pipe Down, Will You? (GenomeWeb News)
Duke's Claudia Gunsch is working on a way to silence genes in bacteria using short, singled-stranded DNA, says MIT's Technology Review . If she can get it to work -- she recently presented a proof-of-concept study at the American Society for Microbiology -- there are a variety of applications, including engineering better biofuels, turning off bacterial antibiotic-resistance genes, and filtering ...

Roche Diagnostics purchases NimbleGen microarray workflow assets from BioMicro Systems (News-Medical-Net)
Roche Diagnostics has purchased assets from BioMicro Systems for all products associated with the Roche NimbleGen microarray workflow. These assets consist of key instrumentation in the comprehensive Roche NimbleGen microarray workflow including the NimbleGen Hybridization Systems (both 4- and 12-bay models).

Ipsen grants Rhythm exclusive global license for melanocortin and ghrelin programs (News-Medical-Net)
Ipsen, a global biotechnology specialty care group, and Rhythm Pharmaceuticals, a biotechnology company developing peptide therapeutics for metabolic diseases, announced today that they have concluded a license agreement for Ipsen’s proprietary peptide therapeutics targeting obesity, metabolic diseases, and gastrointestinal disorders.

InDevR ampliPHOX colormetric detection technology in beta site-testing (EurekAlert!)
( University of Colorado at Boulder ) InDevR, developer of advanced life science products, announced that its ampliPHOX Colorimetric Detection Technology is being beta site tested in anticipation of an upcoming product launch. The original intellectual property was licensed from the University of Colorado at Boulder.

UVA Signs Research Collaboration with Merck & Co., Inc to Discover Women's Reproductive Health Drugs (Newswise)
The University of Virginia (UVA) in Charlottesville today announced that it has entered into a research collaboration with Merck (known as MSD outside the United States and Canada) to discover novel drugs for women's reproductive health.

New Imaging Technology Advances Fingerprint Detection (PhotonicsOnline)
ASU scientist N.J. Tao and his colleagues at the Biodesign Institute have hit on a new, versatile method to significantly improve the detection of trace chemicals important in such areas as national security, human health and the environment.

Research and Markets: Batch Effects and Noise in Microarray Experiments: Sources and Solutions (Business Wire via Yahoo! Finance)
DUBLIN----Research and Markets has announced the addition of John Wiley and Sons Ltd's new report "Batch Effects and Noise in Microarray Experiments: Sources and Solutions" to their offering.

Vermillion Eyeing Return to Nasdaq, Launches OVA1 Ovarian Cancer Test with Quest Dx (GenomeWeb News)
This story originally ran on March 10 and has been updated to include additional information on Medicare's decision to cover OVA1. Vermillion this week launched its OVA1 triage ovarian cancer test as part of its effort to return to commercial viability.

New Imaging Technology Brings Trace Chemicals Into Focus (Medical News Today)
Arizona State Univeristy scientist N.J. Tao and his colleagues at the Biodesign Institute have hit on a new, versatile method to significantly improve the detection of trace chemicals important in such areas as national security, human health and the environment. Tao's team was able to detect and identify tiny particles of the explosive trinitrotoluene or TNT - each weighing less than a ...

Green@Rensselaer: A Semester in the Adirondacks (Newswise)
Rensselaer Polytechnic Institute undergraduate biology student Nicole Nolan recently looked into the murky water of a fish tank here, checking on hundreds of zebra mussel larvae that she studied in the laboratories of the Darrin Fresh Water Institute. Nolan was part of the first class of students to spend an entire "Semester of Study" at the Institute, a Rensselaer research and education ...

Imaging Technology Brings Trace Chemicals Into Focus (redOrbit)
ASU scientist N.J.

Teaching and Scholarship Prize Goes to Evolution Professor (UC Davis News & Information)
Questions matter to Rick Grosberg. That is how he carries out his research on evolution and family conflict, and what he tries to show his students: that science is not just about mastering a body of knowledge, but also about asking the right questions and challenging authority. One question -- "Who is the best professor at UC Davis?" -- was answered today, March 12, when Chancellor Linda Katehi ...

Downloads & Upgrades (GenomeWeb News)
Genedata has released Genedata Analyst , a software platform for statistical analysis and data visualization.

Pocketing $3.7M, Eureka Touts Informatics as Differentiator in Sequencing Services, Microorganism Detection (GenomeWeb News)
Fresh from a $3.7 million financing round, Eureka Genomics is looking to build out both sides of its two-pronged business model, which involves sequencing services as well as internal discovery projects to identify novel microorganisms associated with disease.

In Print (GenomeWeb News)
Babur O, Dogrusoz U, Demir E, Sander C. ChiBE: interactive visualization and manipulation of BioPAX pathway models . [ Bioinformatics . 2010 Feb 1;26(3):429-31]: Describes ChiBE, open source software that features display, navigation, and manipulation of pathway models in BioPAX format.

Bigger not Always Better: Larial Proteomics Endures Homelessness, Proteomics Downturn, and Recession (GenomeWeb News)
In a world in which instinct instructs that to become better a company must get bigger, Larial Proteomics has taken the opposite approach.

Campaign Yields $5.7M to Date for MD Anderson Basic Sciences Institute (GenomeWeb News)
NEW YORK (GenomeWeb News) – The University of Texas MD Anderson Cancer Center's basic sciences research hub is among five virtual institutes that stand to benefit from the $1 billion it is seeking to raise by the end of next year.

New imaging technology brings trace chemicals into focus (Science Daily)
Scientists have hit on a new, versatile method to significantly improve the detection of trace chemicals important in such areas as national security, human health and the environment. The research team was able to detect and identify tiny particles of the explosive trinitrotoluene or TNT -- each weighing less than a billionth of a gram -- on the ridges and canals of a fingerprint.

Prize goes to evolution professor (UC Newsroom)
DAVIS — Questions matter to Rick Grosberg. That is how he carries out his research on evolution and family conflict, and what he tries to show his students: that science is not just about mastering a body of knowledge, but also about asking the right questions and challenging authority.

Leading Entomologists to Gather at UC Riverside to Discuss Vector-Borne Diseases and their Global Impact (UC Riverside)
RIVERSIDE, Calif. – Leading insect vector biologists from around the world will gather at the University of California, Riverside for two days this month to discuss their latest research on vector-borne diseases in humans and plants.

Effects of lifestyle and exposures are mirrored in blood gene expression (Science Daily)
A study by Norwegian and French researchers hopes to provide new understanding of how blood cells adjust gene expression in response to various clinical, biochemical and pathological conditions. The Norwegian Woman and Cancer postgenome study highlights numerous blood gene sets affected by one's physical condition, lifestyle factors and exposure variables.

Seeking 'Next Generation' Treatment For Breast Cancer (Medical News Today)
Many women live with breast cancer that does not respond to standard medical treatment, a condition that researchers at the Virginia G. Piper Cancer Center at Scottsdale Healthcare want to change by aggressively targeting specific genes. Improving quality of life and potentially keeping the cancer under control for a longer period of time are goals of a new clinical trial at the cancer center's ...

FDA Chief Commits to Completing Rx/Dx Codevelopment Guidance This Year, Improving Regulatory Science (GenomeWeb News)
At a luncheon hosted by the Personalized Medicine Coalition last week, FDA Commissioner Margaret Hamburg committed the agency to completing its long-awaited drug/diagnostic codevelopment guidance by year end.

Your family tree plays an important role in your health (La Junta Tribune-Democrat)
Discussing health issues is usually a topic delicately danced around when, in reality, it's better to dive right in and be nosy, says Dr. Alfred George Jr., a geneticist and director of the Vanderbilt Institute for Integrative Genomics. The more details - who, what, when - that you know about your family's medical history, the better off your future generations will be.

Roche to Pump $6M into Andalusian Medical Genome Project (GenomeWeb News)
NEW YORK (GenomeWeb News) – Roche said today that it will collaborate with Spain's Department of Health of Junta de Andalucía on the Medical Genome Project, a research project created to study the genetic underpinnings of rare diseases.

Applied Biosystems’ Microarray Promise: A Chip and a System (GenomeWeb News)
Applied Biosystems clearly believes that customers of microarray technology want a single microarray containing the whole human genome, along with new instrumentation to surround it, the ability to integrate into existing sequencing systems, and access to online databases and content.

Maybe He Could Solve That Data Management Problem (GenomeWeb News)
And you thought learning basic bioinformatics was daunting? Take this as inspiration: a blog post at Engadget reports on 11-year-old Jon Penn , who has been in charge of his elementary school's 60-machine network since the previous admin left last year.

Willful ignorance is not an effective argument against personal genomics [Genetic Future] (ScienceBlogs)
Camilla Long's appallingly bad op-ed piece about personal genomics in the Times is a true masterpiece of unsupported criticism, and an ode to willful ignorance. I'd encourage readers to discover their own favourite errors and misconceptions (there are plenty to go around), but here are some of the more glaring flaws: Read the rest of this post... | Read the comments on this post...

Hydra Genome Sequenced by J. Craig Venter Institute and Multi-National Research Team (PR Newswire via Yahoo! Finance)
Researchers from the J. Craig Venter Institute, along with more than 70 other researchers from around the world, have sequenced and analyzed the genome of Hydra magnipapillata, a fresh water member of the cnidaria -- Â stinging animals that include jellyfish, sea anemones and corals.

US stem cell expert is "hottest" researcher-Thomson (AlertNet)
Source: Reuters (Embargoed for release at 12.01/0401 GMT) * Stem cell science, genomics are hot fields * Researchers are also Nobel candidates By Maggie Fox, Health and Science Editor WASHINGTON, March 15 ( ...

A better genetic test for autism (EurekAlert!)
( Children's Hospital Boston ) A large study from Children's Hospital Boston and the Boston-based Autism Consortium finds that a genetic test that samples the entire genome, known as chromosomal microarray analysis, has about three times the detection rate for genetic changes related to autism spectrum disorders (ASDs) than standard tests.

Autism Consortium study in Pediatrics shows CMA finds more genetic abnormalities than current tests (EurekAlert!)
( Autism Consortium ) The Autism Consortium published the results of its comparison study of genetic testing methods for autism spectrum disorders in the journal Pediatrics today. The study revealed that chromosomal microarray analysis (CMA) had the highest detection rate among clinically available genetic tests for patients with autism spectrum disorders and should be part of the initial ...


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