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Method of the future uses single-cell imaging to identify gene interactions (EurekAlert!)
( Cold Spring Harbor Laboratory ) Cellular imaging offers a wealth of data about how cells respond to stimuli, but harnessing this technique to study biological systems is a daunting challenge. In a study published online in Genome Research, researchers have developed a novel method of interpreting data from single-cell images to identify genetic interactions within biological networks, offering ...
(Feb 8, 2010)
NTU research could lead to cure for malaria (AsiaOne)
RESEARCHERS at Nanyang Technological University's (NTU) School of Biological Sciences have completed the world's first in-depth study of the malaria parasite genome, which could lead to a cure for malaria.
(Feb 9, 2010)
QIAGEN Acquires Exclusive Licence for Key PI3K gene (redOrbit)
VENLO, The Netherlands, February 8 /PRNewswire-FirstCall/ -- QIAGEN (NASDAQ: QGEN; Frankfurt Prime Standard: QIA) today announced that its wholly owned subsidiary DxS has acquired the global and exclusive licence for biomarker PI3K from Johns Hopkins University to develop real-time-PCR and endpoint PCR assays.
(Feb 9, 2010)
IBM Launches Eight-core Power7 Processor, Servers (PC World)
UPDATE: IBM launched its latest eight-core Power7 processor on Monday.
(Feb 9, 2010)
An Early Warning System for Cancer (Technology Review)
Autoantibodies could alert doctors to cancer development. A new screening tool developed by scientists in Denmark may help detect the earliest stages of cancer by taking advantage of the body's own defenses. The researchers constructed a microarray system that analyzes patients' blood for a specific class of immune agents called autoantibodies. These are agents that attack the body's own tissue ...
(Feb 9, 2010)
Alnylam Pharmaceuticals receives 'Notice of Allowance' from USPTO (News-Medical-Net)
Alnylam Pharmaceuticals, Inc., a leading RNAi therapeutics company, announced today that the United States Patent and Trademark Office (USPTO) has awarded a Notice of Allowance for the “Soutschek and Manoharan” patent (Application No. 10/916,185), which covers certain chemically modified siRNAs of any length directed to any target, including siRNAs with sterol conjugates for in vivo delivery.
(Feb 9, 2010)
Boston researchers identify new mechanism that inhibit tumor growth in mice (News-Medical-Net)
A team of researchers, led by Pier Paolo Pandolfi, at Beth Israel Deaconess Medical Center, Boston, has identified a new type of cellular senescence (i.e., irreversible arrest of cell growth) and determined a way to enhance it to suppress prostate tumor development and growth in mice.
(Feb 9, 2010)
QIAGEN Unit And Pfizer Enter Into An Agreement To Develop A Companion Diagnostic For Brain Tumor Patients (PharmaceuticalOnline)
Pfizer Inc. and DxS (a wholly owned subsidiary of QIAGEN N.V.) (Frankfurt, Prime Standard: QIA) today announced that they have entered into an agreement to develop a companion diagnostic test kit for PF-04948568 (CDX-110), an immunotherapy vaccine in development for the treatment of glioblastoma multiforme (GBM).
(Feb 9, 2010)
IDBS Biomarker Discovery and Validation Solution Helps Lung Genomics Research Consortium Manage and Analyze Phenotypic ... (Marketwire via Yahoo! Finance)
GUILDFORD, UK and BURLINGTON, MA--(Marketwire - 02/09/10) - IDBS, the leading worldwide provider of research data management and analytics solutions to R&D organizations, today announced that its Biomarker Discovery and Validation Solution will be a key component in an $11 million National Heart, Lung and Blood Institute (NHLBI) award to create a molecular roadmap for chronic lung diseases. The ...
(Feb 9, 2010)
IDBS Biomarker Discovery and Validation Solution Helps Lung Genomics Research Consortium Manage and Analyze Phenotypic ... (Marketwire)
GUILDFORD, UK and BURLINGTON, MA--(Marketwire - February 9, 2010) - IDBS, the leading worldwide provider of research data management and analytics solutions to R&D organizations, today announced that its Biomarker Discovery and Validation Solution will be a key component in an $11 million National Heart, Lung and Blood Institute (NHLBI) award to create a molecular roadmap for chronic lung ...
(Feb 9, 2010)
Biomarkers' Role in Reducing Drug Development Time and Costs to Boost the European Biomarker Analysis Market, Notes ... (ITNews)
LONDON, February 9 /PRNewswire/ -- Biomarker analysis market has excellent growth potential. The 'omics' revolution of the last decade has ensured that the field of biomarker research will test the frontiers of biomedical research in the coming years.
(Feb 9, 2010)
Researchers explore cellular networks that regulate cell morphology (News-Medical-Net)
Cellular imaging offers a wealth of data about how cells respond to stimuli, but harnessing this technique to study biological systems is a daunting challenge.
(Feb 9, 2010)
Frost & Sullivan estimates European biomarker analysis market revenues to reach $2202M in 2015 (News-Medical-Net)
Biomarker analysis market has excellent growth potential. The 'omics' revolution of the last decade has ensured that the field of biomarker research will test the frontiers of biomedical research in the coming years. Biomarkers have a multitude of applications such as early disease detection, identifying potential drug targets, predicting patient response to medication and accelerating clinical ...
(Feb 9, 2010)
Agendia Receives New York State Laboratory Permit and Laboratory Accreditation by College of American Pathologists (FinanzNachrichten)
Huntington Beach, California and Amsterdam (ots/PRNewswire) - Agendia, a world leader in molecular cancer diagnostics, announced today that it has received ...
(Feb 9, 2010)
Comprehensive Study Using Bioinformatics Predicts the Molecular Causes of Many Genetic Diseases (Newswise)
It is widely known that genetic mutations cause disease. What are largely unknown are the mechanisms by which these mutations wreak havoc at the molecular level, giving rise to clinically observable symptoms in patients. Now a new study using bioinformatics, reports the ability to predict the molecular cause of many inherited genetic diseases. These predictions have led to the creation of a web ...
(Feb 9, 2010)
Can mass spec really do that? (The Scientist)
Unexpected applications of a technique best known as a proteomics powerhouse
(Feb 9, 2010)
IP Roundup (GenomeWeb News)
The University of Arkansas of Little Rock has received US Patent No. 7,659,062, "Gene expression profiling of uterine serous papillary carcinomas and ovarian serous papillary tumors."
(Feb 9, 2010)
New Product Watch (GenomeWeb News)
Roche NimbleGen said last week that it has certified genomics service provider Atlas Biolabs to provide target-enrichment and sequencing services using its technologies.
(Feb 9, 2010)
People in the News (GenomeWeb News)
RainDance Technologies has appointed Sirshendu Roopom Banerjee to be company president and CEO.
(Feb 9, 2010)
Focus Ahead Consulting to Represent Integrated Genomics' Products and Services in Europe (Business Wire via Yahoo! Finance)
ARLINGTON HEIGHTS, Ill.----Integrated Genomics, Inc., a leader in microbial genomic informatics, is collaborating with Focus Ahead Consulting Ltd. in the UK to represent and market microbial genome sequencing and bioinformatics services in Europe.
(Feb 9, 2010)
Reportlinker Adds SNP Genotyping and Analysis Markets (PR Newswire via Yahoo! Finance)
Reportlinker.com announces that a new market research report is available in its catalogue:
(Feb 9, 2010)
Eric Green Takes the Helm at NHGRI; Sees Role for Institute in Clinic (GenomeWeb News)
Eric Green is no stranger to the genomics community or the National Human Genome Research Institute, which he now leads.
(Feb 9, 2010)
IDBS Biomarker Discovery And Validation Solution Helps Lung Genomics Research Consortium Manage And Analyze Phenotypic ... (Medical News Today)
IDBS, the leading worldwide provider of research data management and analytics solutions to R&D organizations, announced that its Biomarker Discovery and Validation Solution will be a key component in an $11 million National Heart, Lung and Blood Institute (NHLBI) award to create a molecular roadmap for chronic lung diseases. The project's infrastructure will be developed and hosted by the new ...
(Feb 9, 2010)
The future of European research (Nature)
With a new research commissioner arriving in Brussels, and big policy changes on the cards, explains how scientists could be affected.
(Feb 9, 2010)
Ligon Discovery and Lycera Collaborate to Develop First-in-Class Drugs for Immune Disorders (PR Newswire via Yahoo! Finance)
Ligon Discovery announced today that it has entered into a collaboration agreement with Lycera Corporation to apply its Small Molecule Microarray screening technology to identify first-in-class drug candidates for immune disorders.
(Feb 9, 2010)
Low forms of cyclin E reduce breast cancer drug's effectiveness (Science Daily)
Overexpression of low-molecular-weight (LMW-E) forms of the protein cyclin E renders the aromatase inhibitor letrozole ineffective among women with estrogen-receptor-positive (ER+) breast cancers, researchers report.
(Feb 9, 2010)
Q&A: Ignite's Dietrich Stephan on Building a New Genome Center to Sequence GWAS Samples, Cancer (GenomeWeb News)
Earlier this week, In Sequence spoke with Dietrich Stephan, Ignite's president and CEO, about how he wants to apply this sequencing power, which will be installed over the course of the year.
(Feb 9, 2010)
Comprehensive study using bioinformatics predicts the molecular causes of many genetic diseases (EurekAlert!)
( Buck Institute for Age Research ) It is widely known that genetic mutations cause disease. What are largely unknown are the mechanisms by which these mutations wreak havoc at the molecular level, giving rise to clinically observable symptoms in patients. Now a new study using bioinformatics, led by scientists at the Buck Institute for Age Research, reports the ability to predict the molecular ...
(Feb 9, 2010)
Austria's Anagnostics to Launch Cylindrical Array Platform by Year End (GenomeWeb News)
Hoping a unique format will open doors in the research and molecular diagnostic markets, Anagnostics Bioanalysis recently began shipping its Hyborg microarray platform, which uses the firm's cylindrical Hybcell microarrays, to early-access customers in Austria and Germany.
(Feb 9, 2010)
Recent Patents of Interest in Proteomics (GenomeWeb News)
US Patent 7,657,387. Method of processing and storing mass spectrometry data . Inventors: Robert Malek; Oliver Lange. Assignee: Thermo Finnigan [now Thermo Fisher Scientific]
(Feb 9, 2010)
Comprehensive study using bioinformatics predicts the molecular causes of many genetic diseases (PhysOrg)
It is widely known that genetic mutations cause disease. What are largely unknown are the mechanisms by which these mutations wreak havoc at the molecular level, giving rise to clinically observable symptoms in patients. Now a new study using bioinformatics, led by scientists at the Buck Institute for Age Research, reports the ability to predict the molecular cause of many inherited genetic ...
(Feb 9, 2010)
Certain genetic profiles associated with recurrence-free survival for non-small cell lung cancer (EurekAlert!)
( JAMA and Archives Journals ) An analysis of genetic and clinical data for nearly 800 patients with non-small cell lung cancer has identified differences in genetic characteristics that are associated with age and sex specific patterns of increased or decreased recurrence-free survival, according to a study in the Feb. 10 issue of JAMA.
(Feb 9, 2010)
Age- and Sex-Specific Genomic Profiles in Non-Small Cell Lung Cancer [Original Contribution] (Journal of the American Medical Association)
Context Gene expression profiling may be useful in examining differences underlying age- and sex-specific outcomes in non–small cell lung cancer (NSCLC). Objective To describe clinically relevant differences in the underlying biology of NSCLC based on patient age and sex. Design, Setting, and Patients Retrospective analysis of 787 patients with predominantly early stage NSCLC performed at ...
(Feb 9, 2010)
Comprehensive study using bioinformatics predicts the molecular causes of many genetic diseases (Science Daily)
It is widely known that genetic mutations cause disease. What are largely unknown are the mechanisms by which these mutations wreak havoc at the molecular level, giving rise to clinically observable symptoms in patients. Now a new study using bioinformatics reports the ability to predict the molecular cause of many inherited genetic diseases. These predictions have led to the creation of a web ...
(Feb 9, 2010)
Integrated Genomics Taps Consulting Firm to Market Microbial Products, Services in Europe (GenomeWeb News)
Integrated Genomics said this week that it is partnering with Focus Ahead Consulting in the UK to market its microbial genome sequencing and bioinformatics products and services in Europe.
(Feb 9, 2010)
Neuroimaging study may pave way for effective Alzheimer's treatments (PhysOrg)
(PhysOrg.com) -- Scientists have determined that a new instrument known as PIB-PET is effective in detecting deposits of amyloid-beta protein plaques in the brains of living people, and that these deposits are predictive of who will develop Alzheimer`s disease.
(Feb 9, 2010)
Certain Genetic Profiles Associated With Recurrence-Free Survival for Non-Small Cell Lung Cancer (Newswise)
An analysis of genetic and clinical data for nearly 800 patients with non-small cell lung cancer has identified differences in genetic characteristics that are associated with age and sex specific patterns of increased or decreased recurrence-free survival, according to a study in the February 10 issue of JAMA.
(Feb 9, 2010)
Brain protein for synapse development identified (Science Daily)
A new study identifies for the first time a brain protein called SynDIG1 that plays a critical role in creating and sustaining synapses, the complex chemical signaling system responsible for communication between neurons.
(Feb 9, 2010)
Low Forms Of Cyclin E Reduce Breast Cancer Drug's Effectiveness (redOrbit)
M. D. Anderson researchers find better way to predict prognosis in patients treated with aromatase inhibitors; research also suggests a potential means of circumventing drug resistanceOverexpression of low-molecular-weight (LMW-E) forms of the protein cyclin E renders the aromatase inhibitor letrozole ineffective among women with estrogen-receptor-positive (ER+) breast cancers, researchers from ...
(Feb 9, 2010)
Mescal 'worm' test shows DNA leaks into preservatives (EurekAlert!)
( International Barcode of Life ) University of Guelph research team use the Mexican liquor mescal (the one with the worm) to prove that the DNA of a preserved specimen can be obtained from the preservative liquid.
(Feb 9, 2010)
Ligon Discovery, Lycera announce collaboration to identify drug candidates for immune disorders (News-Medical-Net)
Ligon Discovery announced today that it has entered into a collaboration agreement with Lycera Corporation to apply its Small Molecule Microarray (SMM) screening technology to identify first-in-class drug candidates for immune disorders. Ligon will apply its SMM technology to screen protein targets identified by Lycera as critical to the development of certain immune disorders. Financial terms ...
(Feb 10, 2010)
BioDiscovery Releases Nexus Copy Number Version 5.0 for DNA Copy Number Analysis and Visualization (PRWeb via Yahoo! News)
BioDiscovery, Inc. a leader in integrated software solutions for microarray-based research, announced today the release of version 5 of its popular Nexus Copy Number software, the leading platform independent and user friendly application for DNA copy number analysis of microarray derived data.
(Feb 10, 2010)
People living with IBD are at high risk of blood clots (News-Medical-Net)
People living with Inflammatory Bowel Disease (IBD) are known to be at high risk of blood clots when admitted to hospital during a flare-up of their disease but now new research by scientists at The University of Nottingham has shown that those who are not admitted to hospital during flare-ups are also at risk.
(Feb 10, 2010)
Kinexus Announces the Launch of a New Protein Kinase Microarray (PR Newswire via Yahoo! Finance)
New kinase array designed for drug screening, substrate profiling and kinase interaction discovery VANCOUVER , Feb. 10 /PRNewswire/ - Kinexus Bioinformatics Corporation announced the commercial release of its novel Protein Kinase Microarray with 200 recombinant human protein kinases for screening. The microarray has wide utility including applications for drug target counter screening, to ...
(Feb 10, 2010)
Researchers find differences in the biology of lung cancer between men and women (News-Medical-Net)
An analysis of genetic and clinical data for nearly 800 patients with non-small cell lung cancer has identified differences in genetic characteristics that are associated with age and sex specific patterns of increased or decreased recurrence-free survival, according to a study in the February 10 issue of JAMA.
(Feb 10, 2010)
Agendia Receives New York State Laboratory Permit And Laboratory Accreditation By College Of American Pathologists (Medical News Today)
Agendia, a world leader in molecular cancer diagnostics, announced that it has received the Clinical Laboratory Permit from the New York State Department of Health. The New York State permit allows the company to receive commercial samples of MammaPrint, its FDA-cleared breast cancer recurrence test. With this latest permit, Agendia has now obtained all major U.S. clinical laboratory licenses ...
(Feb 10, 2010)
Kinexus Bioinformatics announces the commercial release of Protein Kinase Microarray (News-Medical-Net)
Kinexus Bioinformatics Corporation announced the commercial release of its novel Protein Kinase Microarray with 200 recombinant human protein kinases for screening. The microarray has wide utility including applications for drug target counter screening, to identify novel kinase substrates, establish kinase antibody specificities, and for the discovery and testing of protein kinase-protein and ...
(Feb 10, 2010)
Bioinformatics Study Predicts Molecular Causes Of Many Genetic Diseases (redOrbit)
Research spearheaded at Buck Institute results in a web-based tool available to other scientistsIt is widely known that genetic mutations cause disease. What are largely unknown are the mechanisms by which these mutations wreak havoc at the molecular level, giving rise to clinically observable symptoms in patients. Now a new study using bioinformatics, led by scientists at the Buck Institute for ...
(Feb 10, 2010)
Febit (Finally) Ships its Magic Microarray Machine: Sales, US Office Planned for 2004 (GenomeWeb News)
For nearly two years now, German startup Febit has tantalized visitors to conference exhibit halls with displays of its ‘magic’ microarray machine — a silver box with a sleek, curved surface that promises to synthesize custom oligo arrays, perform experiments, and scan the arrays all within the confines of its machinery.
(Feb 10, 2010)
UK's BBSRC Earmarks Cash for Bioinformatics Resources, Systems Bio Tools (GenomeWeb News)
NEW YORK (GenomeWeb News) —The UK’s Biotechnology and Biological Sciences Research Council this week issued two calls for proposals of interest to bioinformatics.
(Feb 10, 2010)
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