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Bioinformatics News 02/2010 (Page 2)

Scientists create new way to screen libraries of 10 million or more compounds (Science Daily)
The search for new drug compounds is probably worse than looking for a needle in a haystack because scientists are limited in the size of the haystacks they can rummage through -- time and money make it virtually impossible to screen or search through super-large libraries of potential compounds. This is a serious problem, because there is enormous interest in identifying synthetic molecules ...

Stem cell research facility opens (UC Newsroom)
RIVERSIDE, Calif.

IP Roundup (GenomeWeb News)
Osmetech of Pasadena, Calif., has received US Patent No. 7,655,129, "Binding acceleration techniques for the detection of analytes." The patent claims methods for accelerating the binding of target analytes to capture ligands on surfaces.

Zygem to Market Rubicon's DNA-Amplification Kits in Australia, New Zealand (GenomeWeb News)
Rubicon Genomics said last week that it has tapped Zygem to market its PicoPlex single-cell amplification kits in Australia and New Zealand.

UC Riverside's new state-of-the-art technology to accelerate stem cell research (PhysOrg)
Stem cell research at the University of California, Riverside is about to gather speed thanks to the establishment of a new Stem Cell Core Facility (SCCF) - a shared facility providing infrastructure, equipment, and trained personnel for doing stem cell research that ordinarily would not be available in most laboratories.

Beckman Coulter Genomics, Genpathway Partner to Provide ChIP-seq Service (GenomeWeb News)
Beckman Coulter Genomics and Genpathway are partnering to provide customers with whole-genome chromatin immunoprecipitation sequencing services, the companies said this week.

Study Finds Histone Modification Levels Can Predict Gene Expression (GenomeWeb News)
NEW YORK (GenomeWeb News) – In a paper appearing online last night in the Proceedings of the National Academy of Sciences , researchers from Germany, Croatia, and Norway report that they have come up with a bioinformatics-based approach for predicting gene expression levels in human cells based on histone modification levels.

France's Institut Pasteur Develops Resequencing Array for Pathogen Identification (GenomeWeb News)
Researchers at the Institut Pasteur's Laboratory for Urgent Response to Biological Threats in Paris have developed a new resequencing microarray for use in public health emergencies triggered by exposure to pathogens.

IP Update: Recent Patents Related to PCR, Sample Prep, and Nucleic Acid Amplification (GenomeWeb News)
US Patent No. 7,655,791. DNA amplification and sequencing using DNA molecules generated by random fragmentation . Inventors: Vladimir Makarov, Irina Sleptsova, Emmanuel Kamberov, Eric Bruening. Assignee: Rubicon Genomics.

Myriad Genetics' Q2 Revenues Rise 11 Percent; Profit up 67 Percent (GenomeWeb News)
NEW YORK (GenomeWeb News) – Myriad Genetics reported after the close of the market Tuesday that its second-quarter revenues climbed 11 percent due primarily to increased sales and marketing efforts and improved physician acceptance of its products.

Millipore's Q4 Revenues up 7 Percent with Currency Boost (GenomeWeb News)
NEW YORK (GenomeWeb News) – Millipore reported after the close of the market Tuesday that its fourth-quarter revenues climbed 7 percent, aided by a 5 percent benefit from foreign currency translation.

Dr. Cohan Studies Mutations, Promiscuous Sex in Bacteria (The Wesleyan Argus)
Bacteria are weird.

Bioinformatics – bringing IT and life sciences together (University of Melbourne University News)
Imagine trying to work through millions of bits of information, attempting to work out why a cell had suddenly turned cancerous, or why, in a population of one billion, some individuals started smoking, while others did not?

Genetic test for 'speed gene' in thoroughbred horses (Science Daily)
Groundbreaking research led by a leading horse genomics scientist in Ireland has resulted in the identification of the 'speed gene' in thoroughbred horses.

OGT Launches New ISCA-Endorsed Cytosure™ Acgh Arrays For Detecting Disease And Syndrome-Related Aberrations (BioresearchOnline)
Oxford Gene Technology (OGT), the pioneer of microarray-based technologies, has introduced three new CytoSure™ ISCA aCGH arrays to meet all resolution, multiplexing and budget requirements.

10 new kits available for fast and simple isolation of nucleic acids from blood, plasma and serum (News-Medical-Net)
Norgen Biotek Corp., an innovative privately held Canadian biotechnology company focusing primarily on advancing powerful tools for nucleic acids (NA) and protein purification, today announced the launch of 10 new kits for the fast and simple isolation of nucleic acids from blood, plasma and serum, including circulating nucleic acids.

Angrist demystifies genomics (The Chronicle)
It’s flashy, it’s new, it’s the hottest thing on the market.

Molecular Devices Returns to Life Sciences Marketplace (ITNews)
SUNNYVALE, California, February 3 /PRNewswire/ -- - New Brand Launched by Molecular Devices, Inc. SUNNYVALE, California, February 3 /PRNewswire/ -- Today, Molecular Devices, Inc.-now part of Danaher Corporation-re-launched the Molecular Devices brand into the life sciences marketplace.

UCR purchases Nikon BioStation CT technology to assist in stem cell research (News-Medical-Net)
Stem cell research at the University of California, Riverside is about to gather speed thanks to the establishment of a new Stem Cell Core Facility (SCCF) - a shared facility providing infrastructure, equipment, and trained personnel for doing stem cell research that ordinarily would not be available in most laboratories.

New resources to support Teva Pharmaceutical Industries' Tjet injector system now available (News-Medical-Net)
Teva Pharmaceutical Industries Ltd. announced today the availability of new resources to support the recently introduced Tjet® injector system, a needle-free device designed to deliver Teva’s TEV-TROPIN® [somatropin (rDNA origin) for injection] brand human growth hormone (hGH) to children who have growth failure due to inadequate secretion of normal endogenous growth hormone.

TGen, Horizon Discovery partner in development of novel cancer cell-lines (News-Medical-Net)
The Translational Genomics Research Institute (TGen) and Horizon Discovery today announced plans to develop human disease models for use in TGen's cancer research.

CLC bio expands bioinformatics consulting organization in North America (PharmaBiz)
CLC bio announced the expansion of North American consulting organization. The organization, based in Washington, will function as an integrated part of CLC bio's global consulting team.

New Way To Screen Libraries Of 10 Million Or More Compounds (Medical News Today)
The search for new drug compounds is probably worse than looking for a needle in a haystack because scientists are limited in the size of the haystacks they can rummage through - time and money make it virtually impossible to screen or search through super-large libraries of potential compounds. This is a serious problem, because there is enormous interest in identifying synthetic molecules that ...

Set platform for harnessing synergy: Guv (New Kerala)
Port Blair, Feb 3 : Andaman and Nicobar Islands Lt Governor Bhopinder Singh today urged all the research institutions of the islands to set up a suitable platform for harnessing synergy among different research institutions for the betterment of the islanders.

Navigenics Raises $18 Million in Series C Financing (Business Wire via Yahoo! Finance)
FOSTER CITY, Calif.----Navigenics, a leading personal genomics company, announced today that the company has raised approximately $18 million of funding. The Procter and Gamble Company, with a worldwide portfolio of leading consumer brands, has joined existing Navigenics investors Kleiner Perkins Caufield and Byers and Mohr Davidow Ventures who also participated in this financing round.

• Nutrition expert lectures in Kannapolis (The Salisbury Post)
By Emily Ford [email protected] KANNAPOLIS â Nutrition scientists at the N.C. Research Campus are working to discover and document genetic differences in people, so doctors can create personalized diets for their patients. Called "individual ...

Rosetta Genomics Announces Issuance of Three U.S. Patents (Business Wire via Yahoo! Finance)
REHOVOT, Israel & PHILADELPHIA----Rosetta Genomics today announced that the United States Patent and Trademark Office has issued three patents to the company covering the composition of matter of human microRNAs.

ATLAS Biolabs GmbH Joins Roche NimbleGen's Certified Service Provider Program for Targeted Enrichment (Business Wire via Yahoo! Finance)
MADISON, Wis.----Roche NimbleGen has announced that ATLAS Biolabs GmbH, a Berlin, Germany-based company, has officially become a Certified Service Provider for NimbleGen Sequence Capture.

Finland invests 1.85 million in pan-European infrastructure for biomedical research (EurekAlert!)
( University of Helsinki ) Finland has made its first specific commitment to the development of European biomedical research infrastructures by supporting a joint pilot infrastructure project in bioinformatics, biobanking and translational research. The initial commitment of 1.85 ($2.6) million is to support preparation and pilot studies in 2010.

Finland Adds $2.6M for European Translational Research Effort (GenomeWeb News)
NEW YORK (GenomeWeb News) – Finland has invested €1.9 million ($2.6 million) to support a pan-European pilot project that will involve bioinformatics, biobanking, and translational research efforts in order to ensure that its scientists are involved in developing European biomedical infrastructures, the European Molecular Biology Laboratory (MBL) said today.

Molecular Devices Returns to Life Sciences Marketplace (redOrbit)
SUNNYVALE, Calif., Feb. 3 /PRNewswire/ -- Today, Molecular Devices, Inc.--now part of Danaher Corporation--re-launched the Molecular Devices brand into the life sciences marketplace.

Talking Genomic Medicine and More (GenomeWeb News)
Science Progress is encouraged by the upcoming meeting of the Secretary’s Advisory Committee for Genetics, Health, and Society at the Department of Health and Human Services, saying that this sort of federal-level discussion of the future of genomic medicine is just what is needed.

This Week in Genome Research (GenomeWeb News)
In the early, online edition of Genome Research this week, MD Anderson Cancer Center researcher Jean-Pierre Issa and his team found DNA methylation levels shifts at some genes in aging mouse tissues.

In ACLU v. Myriad, It's Scientific Accuracy, 0, and Wild Speculation, 1 (GenomeWeb News)
Unless you've been living under a sequencer, you already know that the ACLU v. Myriad gene patent hearings began yesterday . Daily Scan was there for the circus, held in a standing-room-only courtroom in downtown New York. The ACLU attorneys spent much of their time arguing that isolated DNA was not "markedly different" from native DNA, and therefore not eligible for patent protection.

Helicos to Install Second Sequencer at Stanford; Sells Instrument to Private Research Institute (GenomeWeb News)
Helicos BioSciences said today that it will install a second Helicos Genetic Analysis system at Stanford University, and that it has sold an instrument to a private research institute, a deal originally announced a year ago.

TGen and Geisinger Health System announce strategic partnership (EurekAlert!)
( The Translational Genomics Research Institute ) The Translational Genomics Research Institute and Geisinger Health System today announced the signing of a strategic research agreement that provides for a focused look at the gaps in clinical medicine where biomedical research can make a difference.

Geisinger and TGen Announce Strategic Partnership to Shape Future of Personalized Medicine (Newswise)
Geisinger Health System and the Translational Genomics Research Institute (TGen) today announced the signing of a strategic research agreement that provides a focused look at the gaps in clinical medicine where biomedical research can make a difference.

Penn biologists determine microRNA activity is suppressed in mouse ovum (EurekAlert!)
( University of Pennsylvania ) Scientists studying RNA activity, the so-called dark matter of the biological world, may have found the first event in reprogramming a differentiated oocyte into pluripotent blastomeres of the embryo.

Simbios Molecular Dynamics workshop (GenomeWeb News)
On March 1-2, Simbios , the NIH Center for physics-based Simulation of Biological Structures at Stanford University, will be hosting the Molecular Dynamics Workshop Series . The first workshop will cover running and developing MD algorithms on GPUs with OpenMM , a programming library which provides tools for molecular modeling simulation, and PyOpenMM , the Python version of OpenMM.

Scientists map epigenome of human stem cells during development (EurekAlert!)
( Agency for Science, Technology and Research (A*STAR), Singapore ) Singapore and US scientists have mapped major components of the epigenome and DNA methylation for the entire human DNA sequence, and compared three cell types representing three stages of human development.

Roche NimbleGen Array Sales Rise 44 Percent in '09 (GenomeWeb News)
Sales of Roche NimbleGen arrays rose 44 percent in 2009 compared to 2008, fueled by "continued strong performance" of Roche NimbleGen's sequence capture arrays as well as the introduction of its high-throughput MS 200 microarray scanner, according to the firm, the company said this week.

Livestock Genomics, Breeding Wins $11M from USDA (GenomeWeb News)
NEW YORK (GenomeWeb News) –The US Department of Agriculture has awarded nearly $11 million in grants to genomics and genetics studies focused on livestock animal development and breeding.

Dr. Klaus Lindpaintner Begins Serving as Vice President of R&D and CSO for Strategic Diagnostics (Business Wire via Yahoo! Finance)
NEWARK, Del.----SDI , a provider of biotechnology-based products and services, today announced that Dr. Klaus Lindpaintner began serving as Vice President of Research & Development and Chief Scientific Officer on February 1, 2010 as previously disclosed in its January 11, 2010 news release.

Navigenics Nets $18M in Financing Round (GenomeWeb News)
NEW YORK (GenomeWeb News) – Navigenics has reeled in $18 million in Series C financing from an investment round that included The Procter and Gamble Company, Kleiner Perkins Caufield and Byers, and Mohr Davidow Ventures.

Vermillion Closes Settlement Debt with HDC (GenomeWeb News)
NEW YORK (GenomeWeb News) – Health Discovery Corp. today said that it has received the final payment owed to it by Vermillion under a patent infringement lawsuit.

Atlas Biolabs to Offer Roche NimbleGen Target-Enrichment, Sequencing Services (GenomeWeb News)
Roche NimbleGen said today that it has certified genomics service provider Atlas Biolabs to provide target-enrichment and sequencing services using its technologies.

Oxford Nanopore Raises $28 Million to Start Protein Analysis Work, Continue DNA Sequencing Research (GenomeWeb News)
Oxford Nanopore Technologies announced this week it has raised £17.4 million ($28 million) which it will use to start work in protein analysis, in addition to "accelerated" development of its core technology for DNA sequencing and continued work in its lead project in DNA sequencing.

NextGen Developing Biomarker Assays for Takeda (GenomeWeb News)
Biomarker firm NextGen Sciences this week announced it has entered into an agreement with Takeda Pharmaceutical to develop validated protein biomarker assays.

Recent Research Papers of Note (GenomeWeb News)
The authors recently introduced a method to facilitate the analysis of phosphopeptides by performing automated online TiO 2 enrichment of phosphopeptides prior to MS analysis.

University of Pittsburgh Earmarks $350K from NIH Grant for WaferGen Real-Time PCR Studies (GenomeWeb News)
Wafergen Biosystems said this week that researchers at the University of Pittsburgh have earmarked $350,000 from an NIH grant to pay for research that will use Wafergen's SmartChip real-time PCR system as part of a larger multi-institution study on the genomics of chronic lung disease.


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