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UCLA Team Sequences Cell Line, Puts Open Source Software Framework into Production
In their paper, which appeared in last week's PLoS Genetics , the team highlighted "enormous improvements in the throughput of data generation." (Fri, 05 Feb 2010 18:20:18 GMT)
A new Linux flavor for the Cloud
Cloud computing is getting its very own Linux flavor based on the Red-Hat distribution designed expressly for optimizing virtualization technologies like VMware or Xen . CloudLinux (also the name of the startup) can be installed with a single kernel, operating system, and library, and requires only a single copy of Apache which comes bundled with the new distribution. (Fri, 05 Feb 2010 18:20:28 GMT)
It's No Stretch Shoveling Snow Leads To Injuries
When your driveway is covered in snow this winter, your first thought may be to dig yourself out. But before you grab the shovel, physical therapist Dr. Susan Wainwright shares simple tips to prepare for and avoid injuries from shoveling snow. (Fri, 05 Feb 2010 18:51:19 GMT)
Holy Cow
Genomics has revolutionized dairy farming. (Fri, 05 Feb 2010 20:11:04 GMT)
People In The News
NEW YORK (GenomeWeb News) – RainDance Technologies has appointed Sirshendu Roopom Banerjee to be company president and CEO. Banerjee most recently led the Life Science Tools and Diagnostics sector at investment bank Leerink Swann, and he advised healthcare companies at McKinsey and Goldman Sachs. (Fri, 05 Feb 2010 20:50:18 GMT)
Accelrys Sees Revenue Lift in Q3, Breaking Three-Quarter Slide
NEW YORK (GenomeWeb News) – Accelrys reported after the close of the market Thursday that its third-quarter revenues grew 7 percent, breaking a string of revenue declines in the last three consecutive quarters. (Fri, 05 Feb 2010 20:50:29 GMT)
IP Update
US Patent 7,657,378. Computer-based method for identifying peptides useful as drug targets . Inventors: Samir Kumar Brahmachar; Debasis Dash. Assignee: Council of Scientific & Industrial Research, New Delhi, India. (Fri, 05 Feb 2010 20:50:40 GMT)
In Brief This Week: Bio-Rad Laboratories; TGen, Van Andel Research Institute; Infosys, Elan; Dotmatix, Boehringer ...
NEW YORK (GenomeWeb News) – Bio-Rad Laboratories has completed its offer to exchange up to $300 million aggregate principal amount of its 8 percent Senior Subordinated Notes due 2016 for any and all of its outstanding 8 percent Senior Subordinated Notes due 2016 that were issued in a private placement. (Fri, 05 Feb 2010 21:05:30 GMT)
Illumina Says 'Significant Growth' in Sequencing Demand Drove 12-Percent Rise in Q4 Revenue
Illumina this week reported that fourth-quarter revenue increased 12 percent — slightly higher than it projected a few weeks ago — largely resulting from continued growth in sales of its sequencing products. (Fri, 05 Feb 2010 21:50:08 GMT)
Genetics Researcher Ready For Prime Time
If you're a genetic researcher, you're likely familiar with products from Applied Biosystems and Invitrogen, the two companies that merged in November 2008 to form Life Technologies. (Fri, 05 Feb 2010 23:05:32 GMT)
TGen Finalizes Alliance With Van Andel Research Institute
The Translational Genomics Research Institute (TGen) has announced the completion of a strategic alliance and affiliation agreement with the Van Andel Research Institute (VARI) that will maximize the research capabilities of both non-profit institutes. TGen expects the agreement to create a robust basic-science-to-translational delivery platform aimed at developing new tests and treatments for ... (Sat, 06 Feb 2010 11:21:30 GMT)
Tracking The Spread Of Disease, Malware And Power Outages
An assistant professor with the Virginia Tech College of Engineering has won a $750,000 federal grant to formulate a mathematical framework that can track the spread of pandemics among populations and malware across wireless computer networks, as well as how a blackout occurring on one major power grid can cause a cascade of additional neighboring networks to fail. Funded by the U.S... (Sat, 06 Feb 2010 11:22:13 GMT)
QIAGEN Unit And Pfizer Enter Into An Agreement To Develop A Companion Diagnostic For Brain Tumor Patients
Pfizer Inc. (NYSE: PFE) and DxS (a wholly owned subsidiary of QIAGEN N.V.) (NASDAQ: QGEN; Frankfurt, Prime Standard: QIA) announced that they have entered into an agreement to develop a companion diagnostic test kit for PF-04948568 (CDX-110), an immunotherapy vaccine in development for the treatment of glioblastoma multiforme (GBM). Financial terms of the diagnostic agreement have not been ... (Sat, 06 Feb 2010 13:19:08 GMT)
You Could Have the Whole Genome In Your Hand. Do You Want It?
Nestled in the leafy confines of Rockefeller University’s campus on the Upper East Side of Manhattan overlooking the East River, Greg Khitrov’s microarray laboratory is a well-heeled but otherwise typical academic core facility. (Sat, 06 Feb 2010 16:05:49 GMT)
SciLi debuts science center
By: Goda Thangada While finishing touches like the installation of smartboards remain, students can begin holding group study sessions and taking advantage of advising in the third-floor science center. The 4,000 square-foot facility, which will have a grand opening in Mar... (Sat, 06 Feb 2010 21:00:57 GMT)
Biologists determine microRNA activity is suppressed in mouse ovum
Scientists studying RNA activity, the so-called dark matter of the biological world, may have found the first event in reprogramming a differentiated oocyte into pluripotent blastomeres of the embryo. (Sun, 07 Feb 2010 04:24:29 GMT)
Genetic tool for sheep, beef breeders
A new genetic product, or SNP Chip, aimed at assisting sheep breeders and Angus beef breeders with molecular breeding values, has been launched in the United States and will be available in New Zealand later this year. (Sun, 07 Feb 2010 16:14:17 GMT)
Fresh fields for AgResearch CEO
Andy West has regularly championed the value of science in agriculture, and leaves his position as chief executive of AgResearch with some business unfinished. (Sun, 07 Feb 2010 16:14:33 GMT)
Admitting Its Limitations, Bio-Rad Contends SELDI Still Valuable for Biomarker Discovery
In their most extensive public comments about the SELDI platform since Bio-Rad Laboratories acquired it from Ciphergen Biosystems last year, officials from Bio-Rad said that despite its shortcomings, the technology is still a valuable tool in the search for biomarkers. (Sun, 07 Feb 2010 17:05:08 GMT)
Meeting Confirms Bioinformatics Status As Key Technology for Pharmaceutical Cos.
LONDON--"Bioinformatics has moved from high potential to key operational technology," remarked Dominic Clark of Glaxo Wellcome at the start of a conference he chaired here February 15-16. (Sun, 07 Feb 2010 17:05:29 GMT)
Rosetta, Ben Gurion University, Alnylam, Medtronic, Silence, Quark
Rosetta Genomics said this week that it has formed a collaboration with Israel’s Ben Gurion University to develop microRNA-targeting therapeutics against several viruses including the Epstein-Barr virus and herpes simplex viruses. (Sun, 07 Feb 2010 17:05:39 GMT)
Gene that improves quality of reprogrammed stem cells identified by Singapore scientists
( Agency for Science, Technology and Research (A*STAR), Singapore ) In Nature, Singapore scientists report that Tbx3 significantly improves quality of induced pluripotent stem cells. (Sun, 07 Feb 2010 18:26:20 GMT)
Researchers Use New Approach to Identify Threatened Tuna Species
DNA barcoding is not only a useful taxonomic technique, but it can also help save endangered species and verify the accuracy of your dinner menu, says a study done by researchers at the American Museum of Natural History. (Sun, 07 Feb 2010 21:20:31 GMT)
New test Counsyl focuses on classic genetic diseases
With its focus on classic genetic diseases such as cystic fibrosis, the Counsyl “universal genetic test” has a distinctly “retro” feel to it. Many of the ethical issues raised by this new service are not new but rather present new challenges because of the scale and means of delivery. (Sun, 07 Feb 2010 23:06:35 GMT)
Accuri looks to veteran to take it to next level: profitable sale
Having led two Ann Arbor biotech companies to successful sales, Jeffrey Williams hopes to lead another to a profitable exit. (Mon, 08 Feb 2010 01:07:17 GMT)
Searching for Disease Clues in Genetic Diversity
Research on the Mexican genome could broaden the scope of personalized medicine. Over the last few years, scientists have discovered hundreds of genetic variants linked to disease. But the vast majority of that research has focused on people of European, Asian, and African descent. A new effort to catalog genetic diversity among people in Mexico--who along with other Latin Americans have a ... (Mon, 08 Feb 2010 05:18:33 GMT)
IBM Powers Up For Server War
As the Oracle-Sun combo heats up hardware competition, IBM's Power7 servers aim to dominate. (Mon, 08 Feb 2010 06:49:35 GMT)
Exercise won't boost endurance levels for 1 in 5
About one in five people can train all they want but, because of their genetic makeup, are not likely to see much improvement in their endurance levels, an international team of researchers reported Thursday. Still, the authors caution, their findings shouldn't be an excuse to throw away the running shoes. "There is a whole host of other physiological responses" to exercise, such as heart rate ... (Mon, 08 Feb 2010 08:02:49 GMT)
#Ebook Deal of the Day: R in a Nutshell - Only $9.99! Use discount code DDRNT
R in a Nutshell for only $9.99. Use discount code DDRNT to get your savings!... (Mon, 08 Feb 2010 08:35:49 GMT)
IDBS Launches Biomarker Discovery and Validation Solution to Accelerate Biomarker Research
GUILDFORD, UK and BURLINGTON, MA--(Marketwire - 02/08/10) - IDBS, the leading worldwide provider of research data management and analytics solutions to R&D organizations, today announced the launch of the IDBS Biomarker Discovery and Validation Solution, which streamlines biomarker research and improves collaboration, intellectual property (IP) management and scientific understanding of complex ... (Mon, 08 Feb 2010 09:00:00 GMT)
IDBS Launches Biomarker Discovery and Validation Solution to Accelerate Biomarker Research
Integration of InforSense and E-WorkBook Suites Delivers First Biomarker ELN (Mon, 08 Feb 2010 09:07:40 GMT)
OGT introduces CytoSure aCGH arrays for detecting disease, syndrome-related aberrations
Oxford Gene Technology (OGT), the pioneer of microarray-based technologies, has introduced three new CytoSure ISCA aCGH arrays to meet all resolutions, multiplexing and budget requirements. (Mon, 08 Feb 2010 11:43:44 GMT)
MDRNA, Inc. Receives Compliance Extension From NASDAQ
BOTHELL, WA--(Marketwire - February 8, 2010) - MDRNA, Inc. ( NASDAQ : MRNA ) announced that it received a letter on February 5, 2010 from The NASDAQ Stock Market, Inc. notifying the Company that, as a result of Securities and Exchanges Commission (SEC) approved changes to NASDAQ Listing Rules, MDRNA now has a grace period of 180 days from its initial notice of non-compliance in which to regain ... (Mon, 08 Feb 2010 12:38:30 GMT)
Press Release
Molecular Devices Inc. Posted on:05 Feb 10 SUNNYVALE, California, February 3 /PRNewswire/ -- Today, Molecular Devices, Inc.-now part of Danaher Corporation-re-launched the Molecular Devices brand into the life sciences marketplace. (Mon, 08 Feb 2010 13:04:45 GMT)
MDRNA, Inc. Reports Positive Results for Its Proprietary siRNA Delivery Technology
BOTHELL, WA--(Marketwire - 02/08/10) - MDRNA, Inc. (NASDAQ: MRNA - News ), a leading RNAi-based drug discovery and development company, today announced that its lead delivery system formulation demonstrated exceptional stability over a one year period under a variety of conditions. The DiLA2 formulation maintained in vivo knockdown activity with no observed loss in potency over the course of the ... (Mon, 08 Feb 2010 13:30:00 GMT)
MDRNA, Inc. Reports Positive Results for Its Proprietary siRNA Delivery Technology
Data Demonstrates the Potential for Long-Term Stability of Drug Products (Mon, 08 Feb 2010 13:40:38 GMT)
Research and Markets: The World Market Report on Biomarkers, Tests and Trends for Drug R&D
DUBLIN----Research and Markets has announced the addition of the "Biomarkers, Tests and Trends for Drug R&D" report to their offering. (Mon, 08 Feb 2010 15:00:00 GMT)
March of Dimes Helps Nurses Care for Mothers and Babies
New Continuing Nursing Education Modules Now Available (Mon, 08 Feb 2010 15:30:00 GMT)
Life Sells Mass Spectrometry Business
Life Technologies Corporation recently completed the sale of its mass spectrometry business to Danaher Corporation for $450 million in cash (Mon, 08 Feb 2010 15:35:58 GMT)
Institute for Systems Biology Mulls Expansion, Focusing on P4 Efforts
SEATTLE — Approaching its 10th anniversary, the Institute for Systems Biology envisions a near-doubling of its faculty, and its space here, in coming years while moving ahead on several collaborations designed to advance "predictive, preventive, personalized, and participatory," medicine, ISB Co-founder and President Leroy Hood told GenomeWeb Daily News in an interview last week. (Mon, 08 Feb 2010 15:50:08 GMT)
Looking at Diversity
Researchers are hoping to capture some of the diversity seen in Latin Americans through the new Slim Initiative for Genomic Health between the Broad Institute and Mexico City's Carlos Slim Health Institute, says MIT's Technology Review . That project is still in the planning stages — though it will include gene sequencing and microarray-based studies — but INMEGEN published a Mexican version of ... (Mon, 08 Feb 2010 16:50:19 GMT)
Munich Startup Nanotype Forces Its Way into Microarray Market with C-FIT Technology
Finding the right partner is not only a problem that haunts many startup companies. It also may be a major challenge for probe and target molecules on microarrays. (Mon, 08 Feb 2010 17:05:12 GMT)
CDC to Fund Genomics Knowledge Center
NEW YORK (GenomeWeb News) – The Office of Public Health Genomics at the US Centers for Disease Control and Prevention will grant $1.5 million to fund the creation of a center that will help plan and develop systematic evidence reviews on genomics applications, among other efforts. (Mon, 08 Feb 2010 20:50:09 GMT)
DNAVision Adds Illumina HiSeq to Service Offerings
NEW YORK (GenomeWeb News) – DNAVision, a Belgian genomics services provider, today said that it has purchased one of Illumina's new sequencing instruments, the HiSeq 2000, for its service offerings. (Mon, 08 Feb 2010 20:50:18 GMT)
EU, India to Partner on Joint Research Efforts
NEW YORK (GenomeWeb News) – Several European Union member states will partner with India to create a networking pilot program that will enable the partners to share resources and talent and jointly support new diagnostic and biomarker studies. (Mon, 08 Feb 2010 20:50:29 GMT)
QIAGEN Acquires Exclusive Licence for Key PI3K gene
QIAGEN today announced that its wholly owned subsidiary DxS has acquired the global and exclusive licence for biomarker PI3K from Johns Hopkins University to develop real-time-PCR and endpoint PCR assays. (Mon, 08 Feb 2010 21:00:00 GMT)
QIAGEN Reports Strong Fourth Quarter and Fiscal 2009 Results
VENLO, Netherlands -- QIAGEN N.V. today announced the results of operations for the fourth quarter and the fiscal year ended December 31, 2009. (Mon, 08 Feb 2010 21:00:00 GMT)
QIAGEN Acquires Exclusive Licence for Key PI3K gene
VENLO, The Netherlands, February 8 /PRNewswire/ -- - Patent Licensed From Johns Hopkins University for PCR-based Companion Diagnostics for Cancer Treatments QIAGEN (NASDAQ: QGEN; Frankfurt Prime Standard: QIA) today announced that its wholly owned subsidiary DxS has acquired the global and exclusive licence for biomarker PI3K from Johns Hopkins University to develop real-time-PCR and endpoint ... (Mon, 08 Feb 2010 21:11:41 GMT)
IBM launches eight-core Power7 processor, servers
IBM on Monday launched its latest Power7 processor, which adds more cores and improved multithreading capabilities to boost the performance of servers requiring high up time. (Mon, 08 Feb 2010 21:25:40 GMT)
08.02.2010 - PRESS RELEASE: QIAGEN Reports Strong Fourth Quarter and Fiscal 2009 Results
Qiagen N.V. / QIAGEN Reports Strong Fourth Quarter and Fiscal 2009 Results processed and transmitted by Hugin AS. The issuer is solely responsible for the content of this announcement. (Mon, 08 Feb 2010 22:00:59 GMT)
Method of the future uses single-cell imaging to identify gene interactions
( Cold Spring Harbor Laboratory ) Cellular imaging offers a wealth of data about how cells respond to stimuli, but harnessing this technique to study biological systems is a daunting challenge. In a study published online in Genome Research, researchers have developed a novel method of interpreting data from single-cell images to identify genetic interactions within biological networks, offering ... (Mon, 08 Feb 2010 22:26:20 GMT)
NTU research could lead to cure for malaria
RESEARCHERS at Nanyang Technological University's (NTU) School of Biological Sciences have completed the world's first in-depth study of the malaria parasite genome, which could lead to a cure for malaria. (Tue, 09 Feb 2010 01:00:32 GMT)
QIAGEN Acquires Exclusive Licence for Key PI3K gene
VENLO, The Netherlands, February 8 /PRNewswire-FirstCall/ -- QIAGEN (NASDAQ: QGEN; Frankfurt Prime Standard: QIA) today announced that its wholly owned subsidiary DxS has acquired the global and exclusive licence for biomarker PI3K from Johns Hopkins University to develop real-time-PCR and endpoint PCR assays. (Tue, 09 Feb 2010 01:14:42 GMT)
IBM Launches Eight-core Power7 Processor, Servers
UPDATE: IBM launched its latest eight-core Power7 processor on Monday. (Tue, 09 Feb 2010 04:50:58 GMT)
An Early Warning System for Cancer
Autoantibodies could alert doctors to cancer development. A new screening tool developed by scientists in Denmark may help detect the earliest stages of cancer by taking advantage of the body's own defenses. The researchers constructed a microarray system that analyzes patients' blood for a specific class of immune agents called autoantibodies. These are agents that attack the body's own tissue ... (Tue, 09 Feb 2010 05:19:15 GMT)
Alnylam Pharmaceuticals receives 'Notice of Allowance' from USPTO
Alnylam Pharmaceuticals, Inc., a leading RNAi therapeutics company, announced today that the United States Patent and Trademark Office (USPTO) has awarded a Notice of Allowance for the “Soutschek and Manoharan” patent (Application No. 10/916,185), which covers certain chemically modified siRNAs of any length directed to any target, including siRNAs with sterol conjugates for in vivo delivery. (Tue, 09 Feb 2010 06:46:41 GMT)
Boston researchers identify new mechanism that inhibit tumor growth in mice
A team of researchers, led by Pier Paolo Pandolfi, at Beth Israel Deaconess Medical Center, Boston, has identified a new type of cellular senescence (i.e., irreversible arrest of cell growth) and determined a way to enhance it to suppress prostate tumor development and growth in mice. (Tue, 09 Feb 2010 06:46:51 GMT)
QIAGEN Unit And Pfizer Enter Into An Agreement To Develop A Companion Diagnostic For Brain Tumor Patients
Pfizer Inc. and DxS (a wholly owned subsidiary of QIAGEN N.V.) (Frankfurt, Prime Standard: QIA) today announced that they have entered into an agreement to develop a companion diagnostic test kit for PF-04948568 (CDX-110), an immunotherapy vaccine in development for the treatment of glioblastoma multiforme (GBM). (Tue, 09 Feb 2010 08:58:27 GMT)
IDBS Biomarker Discovery and Validation Solution Helps Lung Genomics Research Consortium Manage and Analyze Phenotypic ...
GUILDFORD, UK and BURLINGTON, MA--(Marketwire - 02/09/10) - IDBS, the leading worldwide provider of research data management and analytics solutions to R&D organizations, today announced that its Biomarker Discovery and Validation Solution will be a key component in an $11 million National Heart, Lung and Blood Institute (NHLBI) award to create a molecular roadmap for chronic lung diseases. The ... (Tue, 09 Feb 2010 09:00:00 GMT)
IDBS Biomarker Discovery and Validation Solution Helps Lung Genomics Research Consortium Manage and Analyze Phenotypic ...
GUILDFORD, UK and BURLINGTON, MA--(Marketwire - February 9, 2010) - IDBS, the leading worldwide provider of research data management and analytics solutions to R&D organizations, today announced that its Biomarker Discovery and Validation Solution will be a key component in an $11 million National Heart, Lung and Blood Institute (NHLBI) award to create a molecular roadmap for chronic lung ... (Tue, 09 Feb 2010 09:07:50 GMT)
Biomarkers' Role in Reducing Drug Development Time and Costs to Boost the European Biomarker Analysis Market, Notes ...
LONDON, February 9 /PRNewswire/ -- Biomarker analysis market has excellent growth potential. The 'omics' revolution of the last decade has ensured that the field of biomarker research will test the frontiers of biomedical research in the coming years. (Tue, 09 Feb 2010 10:57:09 GMT)
Researchers explore cellular networks that regulate cell morphology
Cellular imaging offers a wealth of data about how cells respond to stimuli, but harnessing this technique to study biological systems is a daunting challenge. (Tue, 09 Feb 2010 11:02:01 GMT)
Frost & Sullivan estimates European biomarker analysis market revenues to reach $2202M in 2015
Biomarker analysis market has excellent growth potential. The 'omics' revolution of the last decade has ensured that the field of biomarker research will test the frontiers of biomedical research in the coming years. Biomarkers have a multitude of applications such as early disease detection, identifying potential drug targets, predicting patient response to medication and accelerating clinical ... (Tue, 09 Feb 2010 12:01:56 GMT)
Agendia Receives New York State Laboratory Permit and Laboratory Accreditation by College of American Pathologists
Huntington Beach, California and Amsterdam (ots/PRNewswire) - Agendia, a world leader in molecular cancer diagnostics, announced today that it has received ... (Tue, 09 Feb 2010 13:15:30 GMT)
Comprehensive Study Using Bioinformatics Predicts the Molecular Causes of Many Genetic Diseases
It is widely known that genetic mutations cause disease. What are largely unknown are the mechanisms by which these mutations wreak havoc at the molecular level, giving rise to clinically observable symptoms in patients. Now a new study using bioinformatics, reports the ability to predict the molecular cause of many inherited genetic diseases. These predictions have led to the creation of a web ... (Tue, 09 Feb 2010 13:46:36 GMT)
Can mass spec really do that?
Unexpected applications of a technique best known as a proteomics powerhouse (Tue, 09 Feb 2010 17:12:11 GMT)
IP Roundup
The University of Arkansas of Little Rock has received US Patent No. 7,659,062, "Gene expression profiling of uterine serous papillary carcinomas and ovarian serous papillary tumors." (Tue, 09 Feb 2010 17:35:08 GMT)
New Product Watch
Roche NimbleGen said last week that it has certified genomics service provider Atlas Biolabs to provide target-enrichment and sequencing services using its technologies. (Tue, 09 Feb 2010 17:35:18 GMT)
People in the News
RainDance Technologies has appointed Sirshendu Roopom Banerjee to be company president and CEO. (Tue, 09 Feb 2010 17:35:28 GMT)
Focus Ahead Consulting to Represent Integrated Genomics' Products and Services in Europe
ARLINGTON HEIGHTS, Ill.----Integrated Genomics, Inc., a leader in microbial genomic informatics, is collaborating with Focus Ahead Consulting Ltd. in the UK to represent and market microbial genome sequencing and bioinformatics services in Europe. (Tue, 09 Feb 2010 17:47:00 GMT)
Reportlinker Adds SNP Genotyping and Analysis Markets
Reportlinker.com announces that a new market research report is available in its catalogue: (Tue, 09 Feb 2010 18:16:00 GMT)
Eric Green Takes the Helm at NHGRI; Sees Role for Institute in Clinic
Eric Green is no stranger to the genomics community or the National Human Genome Research Institute, which he now leads. (Tue, 09 Feb 2010 18:20:09 GMT)
IDBS Biomarker Discovery And Validation Solution Helps Lung Genomics Research Consortium Manage And Analyze Phenotypic ...
IDBS, the leading worldwide provider of research data management and analytics solutions to R&D organizations, announced that its Biomarker Discovery and Validation Solution will be a key component in an $11 million National Heart, Lung and Blood Institute (NHLBI) award to create a molecular roadmap for chronic lung diseases. The project's infrastructure will be developed and hosted by the new ... (Tue, 09 Feb 2010 18:26:48 GMT)
The future of European research
With a new research commissioner arriving in Brussels, and big policy changes on the cards, explains how scientists could be affected. (Tue, 09 Feb 2010 18:43:53 GMT)
Ligon Discovery and Lycera Collaborate to Develop First-in-Class Drugs for Immune Disorders
Ligon Discovery announced today that it has entered into a collaboration agreement with Lycera Corporation to apply its Small Molecule Microarray screening technology to identify first-in-class drug candidates for immune disorders. (Tue, 09 Feb 2010 18:52:00 GMT)
Low forms of cyclin E reduce breast cancer drug's effectiveness
Overexpression of low-molecular-weight (LMW-E) forms of the protein cyclin E renders the aromatase inhibitor letrozole ineffective among women with estrogen-receptor-positive (ER+) breast cancers, researchers report. (Tue, 09 Feb 2010 19:19:48 GMT)
Q&A: Ignite's Dietrich Stephan on Building a New Genome Center to Sequence GWAS Samples, Cancer
Earlier this week, In Sequence spoke with Dietrich Stephan, Ignite's president and CEO, about how he wants to apply this sequencing power, which will be installed over the course of the year. (Tue, 09 Feb 2010 20:20:18 GMT)
Comprehensive study using bioinformatics predicts the molecular causes of many genetic diseases
( Buck Institute for Age Research ) It is widely known that genetic mutations cause disease. What are largely unknown are the mechanisms by which these mutations wreak havoc at the molecular level, giving rise to clinically observable symptoms in patients. Now a new study using bioinformatics, led by scientists at the Buck Institute for Age Research, reports the ability to predict the molecular ... (Tue, 09 Feb 2010 20:27:20 GMT)
Austria's Anagnostics to Launch Cylindrical Array Platform by Year End
Hoping a unique format will open doors in the research and molecular diagnostic markets, Anagnostics Bioanalysis recently began shipping its Hyborg microarray platform, which uses the firm's cylindrical Hybcell microarrays, to early-access customers in Austria and Germany. (Tue, 09 Feb 2010 21:05:13 GMT)
Recent Patents of Interest in Proteomics
US Patent 7,657,387. Method of processing and storing mass spectrometry data . Inventors: Robert Malek; Oliver Lange. Assignee: Thermo Finnigan [now Thermo Fisher Scientific] (Tue, 09 Feb 2010 21:05:24 GMT)
Comprehensive study using bioinformatics predicts the molecular causes of many genetic diseases
It is widely known that genetic mutations cause disease. What are largely unknown are the mechanisms by which these mutations wreak havoc at the molecular level, giving rise to clinically observable symptoms in patients. Now a new study using bioinformatics, led by scientists at the Buck Institute for Age Research, reports the ability to predict the molecular cause of many inherited genetic ... (Tue, 09 Feb 2010 21:05:42 GMT)
Certain genetic profiles associated with recurrence-free survival for non-small cell lung cancer
( JAMA and Archives Journals ) An analysis of genetic and clinical data for nearly 800 patients with non-small cell lung cancer has identified differences in genetic characteristics that are associated with age and sex specific patterns of increased or decreased recurrence-free survival, according to a study in the Feb. 10 issue of JAMA. (Tue, 09 Feb 2010 21:27:10 GMT)
Age- and Sex-Specific Genomic Profiles in Non-Small Cell Lung Cancer [Original Contribution]
Context Gene expression profiling may be useful in examining differences underlying age- and sex-specific outcomes in non–small cell lung cancer (NSCLC). Objective To describe clinically relevant differences in the underlying biology of NSCLC based on patient age and sex. Design, Setting, and Patients Retrospective analysis of 787 patients with predominantly early stage NSCLC performed at ... (Tue, 09 Feb 2010 21:29:34 GMT)
Comprehensive study using bioinformatics predicts the molecular causes of many genetic diseases
It is widely known that genetic mutations cause disease. What are largely unknown are the mechanisms by which these mutations wreak havoc at the molecular level, giving rise to clinically observable symptoms in patients. Now a new study using bioinformatics reports the ability to predict the molecular cause of many inherited genetic diseases. These predictions have led to the creation of a web ... (Tue, 09 Feb 2010 21:34:47 GMT)
Integrated Genomics Taps Consulting Firm to Market Microbial Products, Services in Europe
Integrated Genomics said this week that it is partnering with Focus Ahead Consulting in the UK to market its microbial genome sequencing and bioinformatics products and services in Europe. (Tue, 09 Feb 2010 21:35:08 GMT)
Neuroimaging study may pave way for effective Alzheimer's treatments
(PhysOrg.com) -- Scientists have determined that a new instrument known as PIB-PET is effective in detecting deposits of amyloid-beta protein plaques in the brains of living people, and that these deposits are predictive of who will develop Alzheimer`s disease. (Tue, 09 Feb 2010 21:35:32 GMT)
Certain Genetic Profiles Associated With Recurrence-Free Survival for Non-Small Cell Lung Cancer
An analysis of genetic and clinical data for nearly 800 patients with non-small cell lung cancer has identified differences in genetic characteristics that are associated with age and sex specific patterns of increased or decreased recurrence-free survival, according to a study in the February 10 issue of JAMA. (Tue, 09 Feb 2010 22:49:42 GMT)
Brain protein for synapse development identified
A new study identifies for the first time a brain protein called SynDIG1 that plays a critical role in creating and sustaining synapses, the complex chemical signaling system responsible for communication between neurons. (Tue, 09 Feb 2010 23:20:17 GMT)
Low Forms Of Cyclin E Reduce Breast Cancer Drug's Effectiveness
M. D. Anderson researchers find better way to predict prognosis in patients treated with aromatase inhibitors; research also suggests a potential means of circumventing drug resistanceOverexpression of low-molecular-weight (LMW-E) forms of the protein cyclin E renders the aromatase inhibitor letrozole ineffective among women with estrogen-receptor-positive (ER+) breast cancers, researchers from ... (Wed, 10 Feb 2010 00:15:43 GMT)
Mescal 'worm' test shows DNA leaks into preservatives
( International Barcode of Life ) University of Guelph research team use the Mexican liquor mescal (the one with the worm) to prove that the DNA of a preserved specimen can be obtained from the preservative liquid. (Wed, 10 Feb 2010 00:26:50 GMT)
Ligon Discovery, Lycera announce collaboration to identify drug candidates for immune disorders
Ligon Discovery announced today that it has entered into a collaboration agreement with Lycera Corporation to apply its Small Molecule Microarray (SMM) screening technology to identify first-in-class drug candidates for immune disorders. Ligon will apply its SMM technology to screen protein targets identified by Lycera as critical to the development of certain immune disorders. Financial terms ... (Wed, 10 Feb 2010 05:39:32 GMT)
BioDiscovery Releases Nexus Copy Number Version 5.0 for DNA Copy Number Analysis and Visualization
BioDiscovery, Inc. a leader in integrated software solutions for microarray-based research, announced today the release of version 5 of its popular Nexus Copy Number software, the leading platform independent and user friendly application for DNA copy number analysis of microarray derived data. (Wed, 10 Feb 2010 07:00:00 GMT)
People living with IBD are at high risk of blood clots
People living with Inflammatory Bowel Disease (IBD) are known to be at high risk of blood clots when admitted to hospital during a flare-up of their disease but now new research by scientists at The University of Nottingham has shown that those who are not admitted to hospital during flare-ups are also at risk. (Wed, 10 Feb 2010 11:54:17 GMT)
Kinexus Announces the Launch of a New Protein Kinase Microarray
New kinase array designed for drug screening, substrate profiling and kinase interaction discovery VANCOUVER , Feb. 10 /PRNewswire/ - Kinexus Bioinformatics Corporation announced the commercial release of its novel Protein Kinase Microarray with 200 recombinant human protein kinases for screening. The microarray has wide utility including applications for drug target counter screening, to ... (Wed, 10 Feb 2010 12:00:00 GMT)
Researchers find differences in the biology of lung cancer between men and women
An analysis of genetic and clinical data for nearly 800 patients with non-small cell lung cancer has identified differences in genetic characteristics that are associated with age and sex specific patterns of increased or decreased recurrence-free survival, according to a study in the February 10 issue of JAMA. (Wed, 10 Feb 2010 12:25:02 GMT)
Agendia Receives New York State Laboratory Permit And Laboratory Accreditation By College Of American Pathologists
Agendia, a world leader in molecular cancer diagnostics, announced that it has received the Clinical Laboratory Permit from the New York State Department of Health. The New York State permit allows the company to receive commercial samples of MammaPrint, its FDA-cleared breast cancer recurrence test. With this latest permit, Agendia has now obtained all major U.S. clinical laboratory licenses ... (Wed, 10 Feb 2010 12:42:48 GMT)
Kinexus Bioinformatics announces the commercial release of Protein Kinase Microarray
Kinexus Bioinformatics Corporation announced the commercial release of its novel Protein Kinase Microarray with 200 recombinant human protein kinases for screening. The microarray has wide utility including applications for drug target counter screening, to identify novel kinase substrates, establish kinase antibody specificities, and for the discovery and testing of protein kinase-protein and ... (Wed, 10 Feb 2010 12:54:44 GMT)
Bioinformatics Study Predicts Molecular Causes Of Many Genetic Diseases
Research spearheaded at Buck Institute results in a web-based tool available to other scientistsIt is widely known that genetic mutations cause disease. What are largely unknown are the mechanisms by which these mutations wreak havoc at the molecular level, giving rise to clinically observable symptoms in patients. Now a new study using bioinformatics, led by scientists at the Buck Institute for ... (Wed, 10 Feb 2010 14:13:12 GMT)
Febit (Finally) Ships its Magic Microarray Machine: Sales, US Office Planned for 2004
For nearly two years now, German startup Febit has tantalized visitors to conference exhibit halls with displays of its ‘magic’ microarray machine — a silver box with a sleek, curved surface that promises to synthesize custom oligo arrays, perform experiments, and scan the arrays all within the confines of its machinery. (Wed, 10 Feb 2010 18:05:19 GMT)
UK's BBSRC Earmarks Cash for Bioinformatics Resources, Systems Bio Tools
NEW YORK (GenomeWeb News) —The UK’s Biotechnology and Biological Sciences Research Council this week issued two calls for proposals of interest to bioinformatics. (Wed, 10 Feb 2010 18:05:29 GMT)
New Product Watch
Kinexus Bioinformatics this week launched its protein kinase microarray with 200 recombinant human protein kinases for screening. (Wed, 10 Feb 2010 19:05:08 GMT)
Whole Genome of Ancient Human Is Decoded
Using a swatch of hair, researchers analyzed the genome of a man who lived on the western coast of Greenland some 4,000 years ago. (Wed, 10 Feb 2010 19:06:50 GMT)
First wild grass species and model system for energy crops sequenced
As the US Department of Energy works toward developing sustainable sources of clean renewable energy, perennial grasses have emerged as major candidates for the commercial production of cellulosic biofuels from feedstocks. However, little is known about the specific biological traits of the grasses that might contribute to their usefulness for energy production, in part because such grasses ... (Wed, 10 Feb 2010 19:20:19 GMT)
Ancient Greenland gene map has a surprise
Scientists have sequenced the DNA from four frozen hairs of a Greenlander who died 4,000 years ago in a study they say takes genetic technology into several new realms. (Wed, 10 Feb 2010 21:44:49 GMT)
Genomics conference set for March
Scripps Translational Science Institute (STSI) will present its third annual educational conference exploring the latest achievements and challenges in the field of genomics on March 5-6. The conference, The Future of Genomic Medicine III, will offer a forum where human geneticists, genomic scientists, physicians and health care professionals of all disciplines can gain valuable insights from ... (Wed, 10 Feb 2010 23:10:53 GMT)
Long-term Comparisons of iPSC and hESC Conducted to Assess Therapeutic Potential
For the first time, scientists have performed a detailed long-term evaluation and comparison of two different types of pluripotent stem cells: human embryonic stem cells and induced pluripotency stem cells . Â Both cell types are believed to share equal characteristics, abilities and potential to differentiate into nearly 220 different cell types. (Thu, 11 Feb 2010 05:01:00 GMT)
Certain genetic profiles associated with recurrence-free survival for non-small cell lung cancer
An analysis of genetic and clinical data for nearly 800 patients with non-small cell lung cancer has identified differences in genetic characteristics that are associated with age and sex specific patterns of increased or decreased recurrence-free survival, according to a new study. (Thu, 11 Feb 2010 05:19:58 GMT)
Ligon Discovery And Lycera Collaborate To Develop First-In-Class Drugs For Immune Disorders
Ligon Discovery announced today that it has entered into a collaboration agreement with Lycera Corporation to apply its Small Molecule Microarray (SMM) screening technology to identify first-in-class drug candidates for immune disorders. Ligon will apply its SMM technology to screen protein targets identified by Lycera as critical to the development of certain immune disorders. (Thu, 11 Feb 2010 06:51:57 GMT)
Long-term Comparisons of iPSC and hESC Conducted to Assess Therapeutic Potential
DURHAM, N.C., Feb. 11 /PRNewswire/ -- For the first time, scientists have performed a detailed long-term evaluation and comparison of two different types of pluripotent stem cells: human embryonic stem cells (hESC) and induced pluripotency stem cells (iPSC). (Thu, 11 Feb 2010 07:13:02 GMT)
QIAGEN and Celera Establish Distribution Agreement for Respiratory Pathogen Panel
VENLO, THE NETHERLANDS--(Marketwire - 02/11/10) - Qiagen N.V. / QIAGEN and Celera Establish Distribution Agreement for Respiratory Pathogen Panel processed and transmitted by Hugin AS. The issuer is solely responsible for the content of this announcement. VENLO, The Netherlands, and ALAMEDA, California -February 11, 2010 - QIAGEN N.V. (NASDAQ: QGEN; Frankfurt Prime Standard: QIA) and Celera ... (Thu, 11 Feb 2010 07:48:00 GMT)
QIAGEN and Celera Establish Distribution Agreement for Respiratory Pathogen Panel
VENLO, THE NETHERLANDS--(Marketwire - February 11, 2010) - (Thu, 11 Feb 2010 07:53:52 GMT)
11.02.2010 - PRESS RELEASE: QIAGEN and Celera Establish Distribution Agreement for Respiratory Pathogen Panel
Qiagen N.V. / QIAGEN and Celera Establish Distribution Agreement for Respiratory Pathogen Panel processed and transmitted by Hugin AS. The issuer is solely responsible for the content of this announcement. (Thu, 11 Feb 2010 08:31:07 GMT)
PAREXEL Enhances Early Phase Biomarker Capabilities Through Alliance With Proteome Sciences
PAREXEL International Corporation , a leading global biopharmaceutical services provider, and Proteome Sciences plc , a leading provider of protein biomarker discovery, validation, and assay development services, today announced the formation of an alliance focused on enhancing PAREXEL's biomarker capabilities for early phase clinical development. Â PAREXEL is using Proteome Sciences' PS ... (Thu, 11 Feb 2010 11:00:00 GMT)
QIAGEN and Celera Establish Distribution Agreement for Respiratory Pathogen Panel
VENLO, Netherlands & ALAMEDA, Calif.----QIAGEN N.V. and Celera Corporation today announced an agreement under which QIAGEN will distribute a Celera molecular multiplex assay. The assay is the next generation version of QIAGEN’s ResPlex II assay for detection of respiratory pathogens. (Thu, 11 Feb 2010 12:00:00 GMT)
Kinexus Announces The Launch Of A New Protein Kinase Microarray
Kinexus Bioinformatics Corporation announced the commercial release of its novel Protein Kinase Microarray with 200 recombinant human protein kinases for screening. The microarray has wide utility including applications for drug target counter screening, to identify novel kinase substrates, establish kinase antibody specificities, and for the discovery and testing of protein kinase-protein and ... (Thu, 11 Feb 2010 13:27:48 GMT)
IBM to Collaborate with Leading Australian Institutions to Push the Boundaries of Medical Research
IBM today announced a Research collaboratory in Melbourne, Australia, where scientists from the Victorian Life Sciences Computational Initiative at the University of Melbourne and the IBM Research Computational Biology Center will use high performance computing â including IBM's Blue Gene supercomputer â to study human disease. (Thu, 11 Feb 2010 16:30:00 GMT)
MWG Biotech to Divest Microarray, Laboratory Automation Product Units
MWG Biotech intends to sell two of its four business units in an effort to refocus the company on its core businesses. (Thu, 11 Feb 2010 19:05:09 GMT)
Chemists create synthetic 'gene-like' crystals for carbon dioxide capture
UCLA chemists report creating a synthetic "gene" that could capture heat-trapping carbon dioxide emissions, which contribute to global warming, rising sea levels and the increased acidity of oceans. (Thu, 11 Feb 2010 19:05:23 GMT)
Axygen, Ariadne Genomics, Pall
Axygen announced last week the release of a new line of crystallography products that includes the Axygem Sitting Drop Crystallography Plate , the Crystallography Plate UltraClear Sealing Film , the Semi-Automated Protein Crystallography Plate and Microplate Sealer , the Crystal Recognition Software , the Crystool software for customizable random crystallization screens, and the Axygen in-house ... (Thu, 11 Feb 2010 19:05:50 GMT)
Wiki-fying a Journal Article
Nature is trying out an idea that Deepak Singh loves . There's a wiki accompanying Lincoln Stein's new paper in Nature Reviews Genetics . (The review discusses biological cyberinfrastructure and is also worth a look .) The sections of the wiki include the major themes of the paper such as centralized online databases and analysis systems, bioinformatics toolkits, the semantic web, and more. (Thu, 11 Feb 2010 19:06:20 GMT)
Mescal worm test shows DNA leaks into preservative liquids
Just because you don't swallow the worm at the bottom of a bottle of mescal doesn't mean you have avoided the essential worminess of the potent Mexican liquor, according to scientists. They have discovered that the liquid itself contains the DNA of the agave butterfly caterpillar -- the famously tasty mescal "worm." (Thu, 11 Feb 2010 19:21:10 GMT)
Dana-Farber Builds Data Collection and Analysis Infrastructure for Lung Disease Genomics Project
Dana-Farber Cancer Institute 's Center for Cancer Computational Biology is building the data-coordination and -analysis infrastructure for the Lung Genomics Research Consortium, which aims to add genetic, genomic, and epigenetic data and analysis tools to an existing clinical biorepository at the National Heart Lung and Blood Institute. (Thu, 11 Feb 2010 23:35:08 GMT)
Food crisis looms warn scientists
A new report by Australian researchers claims far more needs to be done if we're to feed the estimated 9 billion people who will be living on the planet by 2050. (Fri, 12 Feb 2010 02:35:34 GMT)
Food crisis looms, warn scientists
Researchers claim far more needs to be done to feed an estimated 9 billion people living on the planet by 2050. (Fri, 12 Feb 2010 02:55:03 GMT)
Chemists create synthetic 'gene-like' crystals for carbon dioxide capture
Chemists report creating a synthetic "gene," which could capture heat-trapping carbon dioxide emissions. Carbon dioxide contributes to global warming, rising sea levels and increased acidity of oceans. (Fri, 12 Feb 2010 03:21:49 GMT)
CapitalBio officially joins Roche NimbleGen CSP Program
Roche NimbleGen announced today that Beijing-based genomic services provider CapitalBio has officially joined the Roche NimbleGen Certified Service Provider (CSP) Program. (Fri, 12 Feb 2010 06:54:32 GMT)
Ligon Discovery collaborates with Lycera to develop drugs for immune disorders
Ligon Discovery has entered into a collaboration agreement with Lycera Corporation to apply its Small Molecule Microarray (SMM) screening technology to identify first-in-class drug candidates for immune disorders. (Fri, 12 Feb 2010 07:43:44 GMT)
Ancient Greenland gene map reveals surprise
An artist's impression shows "Inuk" who is believed to have lived among the Saqqaq people, the earliest known culture in southern Greenland that lasted from around 2,500 BC until about 800 BC. (Fri, 12 Feb 2010 08:34:41 GMT)
Scientists create synthetic DNA-like crystals for CO2 capture
Washington, Feb 12 : Chemists at University of California Los Angeles (UCLA) have created a synthetic DNA-like crystals that could capture heat-trapping carbon dioxide (CO2) emissions, which contribute to global warming, rising sea levels and the increased acidity of oceans. (Fri, 12 Feb 2010 09:20:39 GMT)
New project to unravel secret lives of cancer cells may help produce new cancer therapies
A team of scientists from Princeton University and The Cancer Institute of New Jersey has embarked on a major new project to unravel the secret lives of cancer cells that go dormant and self-cannibalize to survive periods of stress. The work may help produce new cancer therapies to stem changes that render cancer cells dangerous and resistant to treatment. (Fri, 12 Feb 2010 11:24:22 GMT)
EMBL-EBI hosts ChEMBLdb online database
ChEMBLdb, an online database of information on the properties of more than half a million drug and drug-like small molecules and their targets, has been launched. (Fri, 12 Feb 2010 12:39:22 GMT)
Bacteria Are Better Gene Packers Than We Thought
(PhysOrg.com) -- In microbial genomes, genes are typically depicted as linear series of separate regulatory and coding regions. This leads to the assumption that annotations done by computer to predict such arrangements completely describe the coding capacity of bacterial genomes. (Fri, 12 Feb 2010 13:20:14 GMT)
Long-term Comparisons Of IPSC And HESC Conducted To Assess Therapeutic Potential
For the first time, scientists have performed a detailed long-term evaluation and comparison of two different types of pluripotent stem cells: human embryonic stem cells (hESC) and induced pluripotency stem cells (iPSC). Both cell types are believed to share equal characteristics, abilities and potential to differentiate into nearly 220 different cell types. However, hESC are isolated from early ... (Fri, 12 Feb 2010 13:45:39 GMT)
PAREXEL Enhances Early Phase Biomarker Capabilities Through Alliance With Proteome Sciences
PAREXEL International Corporation (Nasdaq: PRXL), a leading global biopharmaceutical services provider, and Proteome Sciences plc (LSE: PRM), a leading provider of protein biomarker discovery, validation, and assay development services, announced the formation of an alliance focused on enhancing PAREXEL's biomarker capabilities for early phase clinical development. PAREXEL is using Proteome ... (Fri, 12 Feb 2010 13:45:59 GMT)
Chemists Create Synthetic 'Gene-Like' Crystals For Carbon Dioxide Capture
Try 100 timesA few years ago, Yaghi spoke at Shanghai's Fudan University, which is known for having one of the best chemistry departments in China. There, he met Deng, who at the time was an undergraduate student at the university. Deng and his colleagues had tried unsuccessfully to make new MOFs."DJ told me, 'Professor, we tried a slight variation to make new MOFs and it did not work,'" Yaghi ... (Fri, 12 Feb 2010 14:08:35 GMT)
EMBL Launches Online Chemogenomic Database
NEW YORK (GenomeWeb News) – The European Molecular Biology Laboratory has launched an online compound database of information on the properties of over 500,000 drug and drug-like small molecules and their targets, including genomic and chemical data, for use in drug discovery research. (Fri, 12 Feb 2010 15:35:29 GMT)
CDC Official Urges Healthy People 2020 Effort to Expand Genomic Targets
Muin Khoury is depressed over the dearth of genomics-related prevention and education objectives that have been proposed as part of the US federal government's Healthy People 2020 project. (Fri, 12 Feb 2010 15:35:38 GMT)
Team Targets Self-Cannibalizing Cancer Cells
Image 1: To determine whether specific genes play a role in autophagy in proliferating and quiescent cells, Coller's team reduces the activity of these genes and then determines the amount of autophagy within the cell. To assess autophagy levels in one previous experiment, Sarah Pfau, who earned her bachelor's degree from Princeton in 2008, exposed the cells to a fluorescently labeled antibody ... (Fri, 12 Feb 2010 16:15:03 GMT)
Self-cannibalizing cancer cells targeted
Scientists have embarked on a major new project to unravel the secret lives of cancer cells that go dormant and self-cannibalize to survive periods of stress. The work may help produce new cancer therapies to stem changes that render cancer cells dangerous and resistant to treatment. (Fri, 12 Feb 2010 16:21:02 GMT)
Scientists synthesize unique family of anti-cancer compounds
( Yale University ) Yale University scientists have streamlined the process for synthesizing a family of compounds with the potential to kill cancer and other diseased cells, and have found that they represent a unique category of anti-cancer agents. (Fri, 12 Feb 2010 18:32:51 GMT)
Danish-led Team Developing Autoantibodies against O-glycoproteins as Cancer Biomarkers
A Danish-led team of researchers has used array technology to help detect autoantibodies against abnormal glycoproteins in cancer, which could potentially provide a new source of biomarkers to detect the disease. (Fri, 12 Feb 2010 18:35:09 GMT)
BGI to Sequence Tiger, Lion, and Leopard Species This Year
Chinese genomics institute BGI and collaborators are embarking on a project to sequence the genomes of the lion, tiger, and leopard, BGI said this week. (Fri, 12 Feb 2010 18:50:08 GMT)
New Products
Shimadzu Scientific Instruments , Ceres Nanosciences , and Nonlinear Dynamics have partnered to launch the Nanotrap Biomarker Discovery Platform for the enrichment, preservation, and screening of low-level biomarkers directly from complex biological samples. (Fri, 12 Feb 2010 18:50:18 GMT)
Buck Institute Team Puts Semi-Automated Protein Profiling Pipeline to the Test as Web Service
Researchers at the Buck Institute for Age Research have developed a bioinformatics pipeline that can predict how mutations can impact the stability of proteins and lead to disease. (Fri, 12 Feb 2010 19:50:08 GMT)
Downloads and Upgrades
SGI has launched Cyclone , a cloud computing offering for science and engineering applications. It initially supports computational biology, ontologies, computational fluid dynamics, finite element analysis, and computational chemistry and materials research applications, the company said. (Fri, 12 Feb 2010 20:20:18 GMT)
People In The News
NEW YORK (GenomeWeb News) – Agilent Technologies has appointed Robert Schueren to be VP and GM of Genomics, and John Fjeldsted to be GM of Liquid Chromatrography/ Mass Spectrometry. (Fri, 12 Feb 2010 20:35:41 GMT)
New Organization for Clinical Mass Spectrometry Holds its First Conference
SAN DIEGO — With the use of mass spectrometers gaining traction in the clinical laboratory, a new organization formed to promote mass spectrometry and share expertise in the area specifically for clinical applications held its first conference here this week. (Fri, 12 Feb 2010 21:35:12 GMT)
Agilent Fiscal Q1 Revenues Rebound, Growing 4 Percent; Life Science Receipts Jump 10 Percent
A 10-percent jump in life science revenues helped Agilent Technologies grow total revenues for its fiscal first quarter 4 percent, the company said today. (Fri, 12 Feb 2010 21:35:24 GMT)
Blog - Outsourcing Genome Sequencing
China is poised to become the world's sequencing powerhouse. In January, the Beijing Genomics Institute, now known just as BGI, announced it had ordered 126 of Illumina's newest sequencing machines . In a column for Science Progress, stem cell scientist Jeanne Loring notes, "This is the largest order of sequencers ever, anywhere. At a retail price of $690,000 each, even if the machines are ... (Fri, 12 Feb 2010 21:54:50 GMT)
Can deCODE, A Biotech Star Gone Bust, Come Back?
Iceland's deCODE has discovered more genes than any other company on earth. If only it could turn a profit. (Sat, 13 Feb 2010 03:09:10 GMT)
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