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Bioinformatics News 02/2010

Researchers track evolution and spread of drug-resistant bacteria across hospitals and continents (Science Daily)
Researchers have used high resolution genome sequencing to track a particularly virulent strain of MRSA as it traveled between South America, Europe and Southeast Asia. The findings shed light on how these deadly bacteria are able to spread from patient to patient in a single hospital and, on a larger scale of geography and time, between countries and entire continents.

Strong year for biotech (The Edge Daily)
In retrospect, 2009 was a year of strong performance for the Malaysian biotechnology industry. Cynics will protest that we cannot claim that. But why ever not, when tangible evidence-based results abound that testify to the same?

A human being is a union of vertebrate and virus (MalaysiaNews.net)
http://www.newscientist.com/arti The answer to our paradox is now clear: the human genome has evolved as a holobiontic union of vertebr...

New technology to turn patients into doctors (ABC via Yahoo!7 News)
A US doctor is predicting members of the public will soon be able to use technologies like smart phones to monitor and even treat their own health conditions.

Korean scientists announce completion of bovine genome called Hanwoo (PharmaBiz)
Korean scientists announced the completion of the de novo assembly and analysis of the genome of the native Korean bovine, called Hanwoo.

CLC bio Expands Bioinformatics Consulting Organization in North America (Business Wire via Yahoo! Finance)
AARHUS, Denmark----CLC bio announces the expansion of our North American consulting organization. The organization, based in Washington, D.C., will function as an integrated part of CLC bio’s global consulting team.

AB SCIEX Launches as New Company to Extend Leadership in Analytical Science (Business Wire via Yahoo! Finance)
FOSTER CITY, Calif. & CONCORD, Ontario----AB SCIEX today launched as a new company dedicated to life science analytical technologies. The new company combines the two halves of the highly successful AB SCIEX mass spectrometry joint venture into an integrated organization.

Knome Featured in New PBS Series Faces of America with Henry Louis Gates, Jr. (PR Newswire via Yahoo! Finance)
Knome, a leading pioneer in the personal genomics field, will be featured in the new four-part PBS series Faces of America with Henry Louis Gates, Jr. The series follows Harvard scholar Henry Louis Gates, Jr. as he uses advanced genetics tools to explore the ancestral histories of 12 renowned Americans, uncovering unique stories of immigration that illuminate the American experience.

New Computational Tool For Cancer Treatment (Medical News Today)
Many human tumors express indoleamine 2,3-dioxygenase (IDO), an enzyme which mediates an immune-escape in several cancer types. Researchers in the Molecular Modeling group at the SIB Swiss Institute of Bioinformatics and Dr. Benoît J. Van den Eynde's group at the Ludwig Institute for Cancer Research Ltd (LICR) Brussels Branch developed an approach for creating new IDO inhibitors by computer ...

Identification Of Brain Protein For Synapse Development (Medical News Today)
A new study from UC Davis Health System identifies for the first time a brain protein called SynDIG1 that plays a critical role in creating and sustaining synapses, the complex chemical signaling system responsible for communication between neurons. The research, published in the Jan.14 issue of the journal Neuron, fills a major gap in understanding the molecular foundations of higher cognitive ...

Research and Markets: Pharmaceutical Data Mining: Approaches and Applications for Drug Discovery (Business Wire via Yahoo! Finance)
DUBLIN----Research and Markets has announced the addition of John Wiley and Sons Ltd's new report "Pharmaceutical Data Mining: Approaches and Applications for Drug Discovery" to their offering.

MDRNA, Inc. to Present at the 12th Annual BIO CEO & Investor Conference (Marketwire)
Will Also Participate in a Panel Discussion on RNAi-Based Technology

MabCure Featured in GenomeWeb (Business Wire via Yahoo! Finance)
HASSELT, Belgium----MabCure, Inc. , a biotechnology company using its proprietary technology to create highly specific monoclonal antibodies for the early detection of cancer, has been featured in a January 14, 2010 article published on GenomeWeb, the largest online news organization focused on advanced research tools in genomics, proteomics, and bioinformatics.

Research and Markets: Renal and Urinary Proteomics: Methods and Protocols (Business Wire via Yahoo! Finance)
DUBLIN----Research and Markets has announced the addition of John Wiley and Sons Ltd's new report "Renal and Urinary Proteomics: Methods and Protocols" to their offering.

Pathway Genomics Conversation Starter #3: After Genetic Testing, What Then? (Medical News Today)
In the past few years, the science of genetic testing has advanced exponentially, both in the amount of information genetic testing can reveal and the precision and reliability of the results. It's also more convenient and affordable than ever before-making it possible for companies like Pathway Genomics to provide consumers with valuable insight into their predisposition to certain health ...

Rosetta Genomics Fortifies Patent Position With U.S. Allowance Of Claims Covering Human MicroRNAs MiR-21 And Hcmv-miR ... (Medical News Today)
Rosetta Genomics (NASDAQ:ROSG) today announced that the United States Patent and Trademark Office has allowed claims in two patent applications. The first, covering human microRNA miR-21, was derived from the "Tuschl III" patent series that is assigned to the Max Planck Society, Berlin, Germany and is used in Rosetta's miRview™ mets and miRview™ squamous diagnostic assays. Rosetta holds a co ...

Health research one winner in Obama budget (Reuters via Yahoo! News)
Health research is one potential winner in the budget proposed by President Barack Obama Monday, with the National Institutes of Health down for an extra $1 billion for medical research.

International Team Publishes Malaria Parasite GWAS (GenomeWeb News)
NEW YORK (GenomeWeb News) – An international group of researchers has published the first genome-wide association study on the malaria parasite Plasmodium falciparum , looking for genes associated with antimalarial drug resistance and more.

Funding Update (GenomeWeb News)
This project aims to develop efficient simulation techniques for stochastic biochemical models, particularly the cell cycle model. "Biologists have developed complex mathematical models of cell-cycle control in budding yeast, fission yeast, and mammalian cells," the grant abstract states.

Infinitus Clinical Research Consolidates- Sino-Indian CRO Enhances Core Capabilities (redOrbit)
BANGALORE, India, February 1 /PRNewswire/ -- Infinitus Clinical Research is continuing to pioneer its unique strategy.

Spectrometers and Spectrophoto/Fluorometers - Global Market Trends (PR Newswire via Yahoo! Finance)
NEW YORK , Feb. 1 /PRNewswire/ -- Reportlinker.com announces that a new market research report is available in its catalogue: Spectrometers and Spectrophoto/Fluorometers - Global Market Trends http://www.reportlinker.com/p016 Spectroscopic instruments have been crucial in the laboratory since ...

New Report Reviews 28 Collaborative Agreements For The Co-Development Of Drug-Diagnostics (OfficialWire)
The development of genomics-based molecular diagnostics that are linked to therapeutic products is critical to targeted drug developments of the future.

Microarray Papers of Note Published January 2010 (GenomeWeb News)
Journal: Analytical Biochemistry . 2010 Jan 1;396(1):30-5. Title: Quantitative label-free screening for antibodies using scattering biophotonic microarray imaging.

Health spending a winner in Obama budget (Reuters via Yahoo! News)
Health research is a potential winner in the budget proposed by U.S. President Barack Obama on Monday, with the National Institutes of Health in line for an extra $1 billion for medical research.

Study Suggests MicroRNA, Tissue Evolution Closely Linked in Bilaterian Animals (GenomeWeb News)
A team of researchers from Germany and the US used small RNA sequencing, miRNA expression profiling, and comparative genomics to track down the active sites of conserved bilaterian miRNAs during bilaterian animal evolution.

NEI to Support Young Genomics Data Scientists (GenomeWeb News)
NEW YORK (GenomeWeb News) – The National Eye Institute wants more researchers who can use statistical genetics to study ophthalmology, and will award up to $300,000 per year for five years to start training programs to begin cultivating such talent.

Pitt to Use WaferGen SmartChip in NIH-Supported Studies (GenomeWeb News)
NEW YORK (GenomeWeb News) – WaferGen Biosystems said today that the University of Pittsburgh will use its SmartChip Real-Time PCR System in genomics, gene expression, and disease studies that are funded by the National Institutes of Health.

High-throughput analysis of gene regulation, DNA synthesis in Cold Spring Harbor Protocols (EurekAlert!)
A featured article in the February 2010 issue of Cold Spring Harbor Protocols presents a high-throughput method for identifying DNase I hypersensitive sites across the whole genome. Another article presents a method for coupling BrdU immunoprecipitation with DNA microarrays to enable genome-wide identification of BrdU-labeled chromosomal DNA. Both are freely accessible on the Web site for Cold ...

Health spending a winner in Obama budget (Reuters via Yahoo! News)
Health research is a potential winner in the new U.S. budget proposed on Monday, with the National Institutes of Health in line for an extra $1 billion -- the largest increase for the agency in eight years.

Scripps Research scientists create new way to screen libraries of 10 million or more compounds (EurekAlert!)
( Scripps Research Institute ) The search for new drug compounds is probably worse than looking for a needle in a haystack because scientists are limited in the size of the haystacks they can rummage through -- time and money make it virtually impossible to screen or search through super-large libraries of potential compounds. This is a serious problem, because there is enormous interest in ...

Children's Hospital Boston Researchers ID Protein That May Explain Paclitaxel Resistance (GenomeWeb News)
Researchers from Children's Hospital Boston have used a proteomics approach to identify a protein that may play a key role in determining why some patients fail to respond to one of the most successful cancer treatments in history.

Scientists create new way to screen libraries of 10 million or more compounds (PhysOrg)
The search for new drug compounds is probably worse than looking for a needle in a haystack because scientists are limited in the size of the haystacks they can rummage through -time and money make it virtually impossible to screen or search through super-large libraries of potential compounds. This is a serious problem, because there is enormous interest in identifying synthetic molecules that ...

Jocelyn Rose to lead Institute for Biotechnology and Life Sciences Technologies (Cornell News Service)
Jocelyn Rose, professor of plant biology, has been named the new director of the Institute for Biotechnology and Life Science Technologies, effective Jan. 1.

Scripps Research Scientists Create New Way To Screen Libraries Of 10 Million Or More Compounds (redOrbit)
The search for new drug compounds is probably worse than looking for a needle in a haystack because scientists are limited in the size of the haystacks they can rummage through—time and money make it virtually impossible to screen or search through super-large libraries of potential compounds.

SOLiD Gold: Dietrich Stephan on Ignite’s Partnership with Life Technologies (Bio-IT World)
Bio-IT World | Dietrich Stephan, the co-founder of personal genomics company Navigenics, speaks to Bio-IT World about his ambitious new institute in Northern Virginia – the Ignite Institute for Individualized Health; the newly announced partnership with Life Technologies; and the acquisition of 100 SOLiD 4 next-generation sequencing instruments.

Project set to map marks on genome (Nature)
Consortium sets sights on the differences that make us different.

Cardiac catheterization: A groundbreaking tool in the field of cardiology (News-Medical-Net)
Cardiac catheterizations have been a groundbreaking tool in the field of cardiology. This procedure offers a minimally invasive means for obtaining important information about the heart and its blood vessels, while also providing a less invasive treatment for certain heart conditions.

Scripps Research Scientists Create Innovative New Way To Screen Libraries Of 10 Million Or More Compounds, Potentially ... (ChemicalOnline)
The search for new drug compounds is probably worse than looking for a needle in a haystack because scientists are limited in the size of the haystacks they can rummage through-time and money make it virtually impossible to screen or search through super-large libraries of potential compounds.

Researchers Sequence Complete Genome Of Brain Cancer Cell Line (Medical News Today)
Cancer researchers at UCLA's Jonsson Comprehensive Cancer Center have performed the complete sequencing of the much-studied brain cancer cell line, U87, a discovery that may lead to targeted treatments for glioblastoma based on the unique biological signature of an individual's disease, the development of more effective and less toxic drug therapies for this aggressive tumor, and the tools to ...

Biotech Stock Alert for Power 3 Medical Products Inc. Issued by Beacon Equity (GlobeNewswire via Yahoo! Finance)
DALLAS -- BeaconEquity.com announces an investment report featuring biotechnology company Power 3 Medical Products Inc. . The report includes financial, comparative and investment analyses, and industry information you need to know to make an educated investment decision.

Spectrometers And Spectrophoto/Fluorometers - Global Market Trends (PharmaceuticalOnline)
Reportlinker.com announces that a new market research report is available in its catalogue: Spectrometers and Spectrophoto/Fluorometers - Global Market Trends , http://www.reportlinker.com/p016

Dicerna to Present New Data on Dicer Substrate siRNA Molecules at Cambridge Healthtech Institute's Second Annual RNA ... (Business Wire via Yahoo! Finance)
WATERTOWN, Mass.----Dicerna Pharmaceuticals, Inc., a second generation RNA interference company developing novel therapeutics utilizing its proprietary Dicer Substrate Technology™ and Dicer Substrate siRNA molecules, today announced that the company will present new preclinical data at the Cambridge Healthtech Institute’s Second Annual RNA Interference: From Tools to Therapies Conference, as ...

CombiMatrix to Spend $25M Insurance Settlement on 'All Aspects of Business' (GenomeWeb News)
After years of requiring cash infusions to keep its nascent diagnostics business on track, CombiMatrix last week disclosed in a filing with US Securities and Exchange Commission that it has inked a settlement agreement with National Union Fire Insurance Company, under which CombiMatrix will receive $25 million, essentially ending its financing woes.

ACLA Briefs Blues Chapter About 'Value of Genetic Testing' (GenomeWeb News)
ACLA and Results for Life recently briefed officials at Carefirst Blue Cross and Blue Shield in Baltimore about "the value and importance of genetic testing," according to ACLA.

TGen becomes center of excellence for Horizon Discovery's GENESIS and X-MAN technology (EurekAlert!)
( The Translational Genomics Research Institute ) The Translational Genomics Research Institute and Horizon Discovery today announced plans to develop human disease models for use in TGen's cancer research.

Beckman Coulter, Genpathway Collaborate on ChIP-Seq Services (GenomeWeb News)
NEW YORK (GenomeWeb News) – Beckman Coulter Genomics, the genomics services subsidiary of Beckman Coulter, today said that it is teaming up with Genpathway to offer customers whole-genome chromatin immunoprecipitation sequencing (ChIP-Seq) services.

SAIC-Frederick Awards SDI Contract to Develop Antibodies for NCI's Proteomics Initiative (GenomeWeb News)
Strategic Diagnostics this week announced that Science Applications International Corp.-Frederick has chosen it to develop monoclonal antibodies as part of the National Cancer Institute's initiative to improve reagents for the proteomics community.

Beckman Coulter Genomics Partners with Genpathway to Offer Comprehensive ChIP-Seq Solutions (dBusinessNews.com)
DANVERS, Mass., and SAN DIEGO – (Feb. 2, 2010) – Beckman Coulter Genomics Inc., and Genpathway, Inc., today announced a strategic partnership to offer customers whole-genome chromatin immunoprecipitation sequencing (ChIP-Seq) services.

UC Riverside’s New State-of-the-art Technology to Accelerate Stem Cell Research (UC Riverside)
RIVERSIDE, Calif.

Research advances microsystems that can detect water-borne pathogens (Science Daily)
Researchers have engineered microsystems for the detection of water-borne pathogens using a technique called dielectrophoresis (DEP), which separates and identifies cells and microparticles suspended in a medium based on their size and electrical properties. Now they have found a way to provide the nonuniform electric field required for DEP that does not require electrodes to contact the sample ...


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