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GMU Developing Proteomic Profile to Personalize Gleevec Treatment for CRC; Novartis Provides Funding
George Mason University researchers are working with the cancer division at Inova Health System in Virginia to identify markers that may eventually lead to the first protein activation companion assay, allowing doctors to personalize the treatment of late-stage colorectal cancer patients with the oncologic Gleevec. (Wed, 20 Jan 2010 17:50:08 GMT)
Coriell Forms New PGx Advisory Group; FDA Genomics Head Zineh Appointed Chair
The Coriell Personalized Medicine Collaborative has formed a new Pharmacogenomics Advisory Group headed by a top FDA official that will advise researchers about potentially actionable gene-drug combinations for inclusion in their projects. (Wed, 20 Jan 2010 18:00:33 GMT)
Carlos Slim Funds Genomics Research
Mexico's richest man commits millions to diabetes, cancer and kidney disease research. (Wed, 20 Jan 2010 18:18:13 GMT)
Scientists Show How Brain Tumors Outsmart Drugs
Researchers at the Ludwig Institute for Cancer Research (LICR) at the University of California, San Diego School of Medicine and Moores UCSD Cancer Center have shown one way in which gliomas, a deadly type of brain tumor, can evade drugs aimed at blocking a key cell signaling protein, epidermal growth factor receptor (EGFR),that is crucial for tumor growth. (Wed, 20 Jan 2010 19:08:20 GMT)
Mexican Magnate Provides $65M for Broad Partnership
NEW YORK (GenomeWeb News) – The Carlos Slim Institute of Health has pledged $65 million to a partnership with the Broad Institute of MIT and Harvard and the National Institute for Genomic Medicine in Mexico for genomics-focused disease studies, Broad said today. (Wed, 20 Jan 2010 20:45:42 GMT)
DiaGenic Taps Ferrer InCode as Distributor
NEW YORK (GenomeWeb News) – Norwegian gene expression-based diagnostics company DiaGenic said today that it has signed up Ferrer InCode to distribute its Alzheimer's disease test in certain countries in Europe and Latin America. (Wed, 20 Jan 2010 20:45:52 GMT)
EBI Funding Falls 10 Percent in 2009
Total funding for EBI dipped roughly 10 percent, to €39 million in 2009 from more than €43.2 million in 2008 — despite a 3 percent rise in internal funding from its parent organization, the European Molecular Biology Laboratory, from €19.4 million in '08 to €20 million last year. (Wed, 20 Jan 2010 20:46:03 GMT)
National Cancer Institute seeks tools for electronic data management
The National Cancer Institute expects to issue a request for proposals next month to identify a contractor that can expand use of electronic data. (Wed, 20 Jan 2010 21:51:01 GMT)
Drug Discovery in Dundee: A Q&A with Andrew Hopkins
Bio-IT World | While working at Pfizer 9 years ago, Andrew Hopkins and his colleague Colin Groom coined the phrase “the druggable genome”—a systematic analysis of the number of druggable targets in the human genome. In 2007, Hopkins made the bold decision to quit industry for academia. Now, with patents filed, compounds being synthesized, biophysics and informatics operations up and running ... (Thu, 21 Jan 2010 07:57:09 GMT)
Affomix, City of Hope enter collaboration on clinical utility of digital proteomics
Affomix Corporation, a pioneer in high performance antibody technology, announced a collaboration with City of Hope focused on establishing the clinical utility of “digital proteomics” with next generation sequencers. (Thu, 21 Jan 2010 08:36:25 GMT)
Drug Discovery Database Goes Live with 2.4 Million Records
Bio-IT World | ChEMBLdb , a vast open-source database of the properties and activities of drugs and drug-like small molecules and their targets, launched this week with information on over half a million compounds. (Thu, 21 Jan 2010 09:27:11 GMT)
Illumina to Announce Fourth Quarter and Fiscal Year 2009 Financial Results on Thursday, February 4, 2010
SAN DIEGO----Illumina, Inc. today announced that it will issue results for fourth quarter and fiscal year 2009 following the close of market on Thursday, February 4, 2010. (Thu, 21 Jan 2010 11:00:00 GMT)
TriLink BioTechnologies and Nacalai USA enter into distribution agreement
TriLink BioTechnologies (TriLink), has entered into an agreement with Nacalai USA, Inc., a San Diego based manufacturing and marketing company, for the distribution of TriLink's modified nucleic acid products in Japan, Singapore, South Korea and Taiwan. (Thu, 21 Jan 2010 11:41:53 GMT)
Scientists Show How Brain Tumors Outsmart Drugs
Researchers at the Ludwig Institute for Cancer Research (LICR) at the University of California, San Diego School of Medicine and Moores UCSD Cancer Center have shown one way in which gliomas, a deadly type of brain tumor, can evade drugs aimed at blocking a key cell signaling protein, epidermal growth factor receptor (EGFR),that is crucial for tumor growth. In a related finding, they also proved ... (Thu, 21 Jan 2010 12:00:29 GMT)
Guide to Genomic Research Ethics
A new consensus statement in PLoS Biology might be of some interest to consumer genomics companies , blogs Hsien-Hsien Lei. The statement explores issues surrounding consent, duty to disclose, withdrawing from research, return of results, and the release of data to the public and how those topics are a bit trickier with whole-genome studies. (Thu, 21 Jan 2010 12:15:52 GMT)
MDRNA, Inc. Announces Allowance of European Patent Covering Formulations for Rapid Acting Insulin
BOTHELL, WA--(Marketwire - 01/21/10) - MDRNA, Inc. (NASDAQ: MRNA - News ), a leading RNAi-based drug discovery and development company, today announced that the European Patent Office intends to grant a patent for application EP06826368 covering formulations for the intranasal delivery of rapid acting insulin, and its use for the treatment of diabetes. "While our focus remains the development of ... (Thu, 21 Jan 2010 13:30:00 GMT)
MDRNA, Inc. Announces Allowance of European Patent Covering Formulations for Rapid Acting Insulin
Allowance Further Strengthens Intranasal IP Portfolio and Potential for Out-Licensing Assets (Thu, 21 Jan 2010 13:32:37 GMT)
Report: Medical Device Market Has A Current Potential Of $454.3 Billion And Are Expected To Grow At A CAGR Of 9.8 ...
Technological innovations in the medical device industry have led to a radical transformation in patient care. This report identifies the sectors with the industry's most important developments related to patient care, clinical outcomes, and new product development. (Thu, 21 Jan 2010 13:43:34 GMT)
Nacalai to Distribute TriLink Tools in Asia
NEW YORK (GenomeWeb News) – TriLink BioTechnologies said today that Nacalai USA will distribute TriLink's nucleic acid products in certain Asian countries. (Thu, 21 Jan 2010 15:46:03 GMT)
Rosetta Genomics Completes $5.1M Financing
Rosetta Genomics Ltd. has completed its previously announced registered direct offering with several institutional investors of approximately $5.1 million of securities. Rosetta has received net proceeds of approximately $4.5 million after deducting placement agent fees and other offering expenses. (Thu, 21 Jan 2010 15:54:57 GMT)
Ultrasound plus proteomic blood analyses may help physicians diagnose early-stage ovarian cancer
( American College of Radiology / American Roentgen Ray Society ) Noninvasive contrast-enhanced ultrasound imaging, combined with proteomic analyses of blood samples may help physicians identify early-stage ovarian cancer and save the lives of many women, according to an article published in the February issue of the American Journal of Roentgenology. Proteomics is the study of proteins ... (Thu, 21 Jan 2010 16:28:52 GMT)
Ultrasound plus proteomic blood analyses may help physicians diagnose early-stage ovarian cancer
Noninvasive contrast-enhanced ultrasound imaging, combined with proteomic analyses of blood samples may help physicians identify early-stage ovarian cancer and save the lives of many women, according to an article published in the February issue of the American Journal of Roentgenology. Proteomics is the study of proteins, particularly their structure and function. (Thu, 21 Jan 2010 17:16:33 GMT)
The University Times | The University of North Carolina at Charlotte's Student Newspaper Since 1949
UNC Charlotte is not a small campus, and if anything projected about our future remains consistent, it is our growth as a university. Growth can mean a lot of different things. (Thu, 21 Jan 2010 18:03:14 GMT)
Acceleration roundup for bioinformatics analysis
Martin Gollery , senior bioinformatics scientist at Tahoe Informatics , has a thorough rundown and analysis of currently available acceleration technologies for bioinformatics. (Thu, 21 Jan 2010 19:00:32 GMT)
Combo Test Might Spot Ovarian Cancer Early
THURSDAY, Jan. 21 (HealthDay News) -- The ability to detect early-stage ovarian cancer may be improved by using contrast-enhanced ultrasound combined with proteomic analyses of blood samples, a new study shows. (Thu, 21 Jan 2010 19:03:16 GMT)
Pathway Genomics Conversation Starter #2: Why Do Genetic Testing?
SAN DIEGO----Does the term “genetic testing” conjure up thoughts of cloned, robot-like human beings and malevolent plots to rule the world? If so, you’ve been reading too much science fiction! (Thu, 21 Jan 2010 20:35:00 GMT)
Combo Test Might Spot Ovarian Cancer Early
Enhanced ultrasound and protein analysis could save lives, researcher says. (Thu, 21 Jan 2010 20:40:31 GMT)
FDA Licenses IO Informatics' Sentient Software
NEW YORK (GenomeWeb News) – The US Food and Drug Administration has licensed IO Informatics' software in its Center for Veterinary Medicine to handle and use data and to reduce its reliance on animal testing, the company said today. (Thu, 21 Jan 2010 20:45:32 GMT)
European Commission OKs Agilent's Acquisition of Varian; FTC Approval Still Pending
Agilent Technologies moved one step closer to finalizing its planned $1.5 billion purchase of Varian this week as the European Commission conditionally cleared the acquisition. (Thu, 21 Jan 2010 21:16:25 GMT)
Study shows value of sexual reproduction versus asexual reproduction
( University of Iowa ) Living organisms have good reason for engaging in sexual, rather than asexual, reproduction according to Maurine Neiman, assistant professor of biology in the UI College of Liberal Arts and Sciences and researcher in the Roy J. Carver Center for Genomics. (Thu, 21 Jan 2010 21:21:20 GMT)
Nacalai to Distribute TriLink's Nucleic Acid Products in Asia
TriLink BioTechnologies this week announced that Nacalai, a manufacturing and marketing company based in San Diego, Calif., will distribute its modified nucleic acid products in Japan, Singapore, South Korea, and Taiwan. (Thu, 21 Jan 2010 22:00:32 GMT)
Ultrasound Plus Proteomic Blood Analyses May Help Physicians Diagnose Early-Stage Ovarian Cancer
Noninvasive contrast-enhanced ultrasound imaging, combined with proteomic analyses of blood samples may help physicians identify early-stage ovarian cancer and save the lives of many women, according to an article published in the February issue of the American Journal of Roentgenology. (Fri, 22 Jan 2010 00:09:51 GMT)
Nebraska regents to decide university budget at upcoming meeting
By: Katie Steiner For its first meeting of the new year, the University of Nebraska Board of Regents will once again be discussing the issue that took up most of its time last year: the university’s budget. ... (Fri, 22 Jan 2010 01:56:35 GMT)
New Saliva Test & Biopsy Process Latest Weapon in War Against Birth Defects
Florida's largest fertility clinic announced it is the first in the state to offer the latest weapon in the war against birth defects: a coupling of technologies that will allow couples to avoid passing along more than 100 genetic diseases to their newborn. (Fri, 22 Jan 2010 02:26:00 GMT)
Waters to focus on emerging markets like India for growth opportunities
Waters Corporation, the US-based lab water major, views the emerging markets as its next destination for growth opportunities. The company has an India strategy in place because of the high growth potential in generics development, clinical research and bio-pharma research. (Fri, 22 Jan 2010 02:37:05 GMT)
Combo Test Might Spot Ovarian Cancer Early
Enhanced ultrasound and protein analysis could save lives, researcher says. (Fri, 22 Jan 2010 05:21:33 GMT)
New Saliva Test & Biopsy Process Latest Weapon in War Against Birth Defects
MARGATE, Fla., Jan. (Fri, 22 Jan 2010 06:07:51 GMT)
New Saliva Test & Biopsy Process Will Reduce Preventable Incidence of Genetic Diseases
MARGATE, Fla., Jan. (Fri, 22 Jan 2010 06:08:00 GMT)
Speed Gene Makes Picking Racehorses a Safer Bet (Update1)
A speed gene in horses is enabling thoroughbred owners to sort would-be sprinters from plodders from just a teaspoonful of the galloper’s blood. (Fri, 22 Jan 2010 06:23:57 GMT)
Combination of saliva test with ultra high-tech biopsy process may help prevent genetic disorders
Florida's largest fertility clinic announced it is the first in the state to offer promising new tests against birth defects: a coupling of technologies that will allow couples to avoid passing along more than 100 genetic diseases to their newborn. (Fri, 22 Jan 2010 06:25:14 GMT)
Scientists show how brain tumors outsmart drugs
Researchers have shown one way in which gliomas, a deadly type of brain tumor, can evade drugs aimed at blocking a key cell signaling protein, epidermal growth factor receptor, that is crucial for tumor growth. (Fri, 22 Jan 2010 06:26:29 GMT)
GATC Biotech Orders Europe's First HiSeq 2000 For Commercial Use
GATC Biotech today announced the purchase of Illumina's new HiSeq 2000 sequencing platform, which has officially been launched last week. This latest acquisition will further strengthen GATC Biotech's current fleet of three GA IIx. (Fri, 22 Jan 2010 10:52:20 GMT)
The Global Biomarker Market Is Estimated To Be $20.5 Billion By 2014, Growing At A CAGR Of 19.7 % From 2009 To 2014
The Global Biomarker Market report analyzes the biomarker tools and services market over the period 2009-2014. (Fri, 22 Jan 2010 11:42:12 GMT)
Israeli Start-Up Launches Database for Glycans, New Encoding Language
MACCABIM, Israel, Nov 16 – Israeli start-up Glycominds has developed a new platform for the systematic study of glycans, complex carbohydrates that bind with proteins and lipids to determine their function. (Fri, 22 Jan 2010 13:15:52 GMT)
New York University, Institute for Systems Biology, University of Washington, Genedata, NHLBI, GeneGo, Genomatica, DSM ...
The Human Proteome Folding Project — a collaborative effort between New York University, the Institute for Systems Biology, and the University of Washington — entered its second phase as of June 23. (Fri, 22 Jan 2010 13:16:02 GMT)
Saving the $2,500 and Getting Alzheimer's Anyway Still Seems Like a Raw Deal
Discover magazine's January issue includes an article on personal genomics , leading with Navigenics' plan to offer kits for $2,500 in the spring. (Fri, 22 Jan 2010 13:16:22 GMT)
Sunflower DNA map could produce plants for fuel
Behemoth oil giant Exxon Mobile has announced that it will invest $600 million in producing liquid fuel from algae. It will spend $300 million on in-house research and partner with Synthetic Genomics,... (Fri, 22 Jan 2010 14:20:14 GMT)
Study Shows Value Of Sexual Reproduction Versus Asexual Reproduction
Living organisms have good reason for engaging in sexual, rather than asexual, reproduction according to Maurine Neiman, assistant professor of biology in the UI College of Liberal Arts and Sciences and researcher in the Roy J. Carver Center for Genomics. In an article published in a recent issue of the journal Molecular Biology and Evolution, she and her colleagues, including John M. Logsdon Jr ... (Fri, 22 Jan 2010 15:28:29 GMT)
Caprion Buys PPD's Biomarker Business
NEW YORK (GenomeWeb News) – Caprion Proteomics said today that it has acquired the biomarker services division of PPD, a contract research firm focused on pharmaceutical services based in Wilmington, NC, for an undisclosed sum. (Fri, 22 Jan 2010 15:30:32 GMT)
Complete Genomics Named a Red Herring Global 100 Award Winner
MOUNTAIN VIEW, Calif.----Complete Genomics Inc., a third-generation human genome sequencing company, today announced that it has been selected as a 2009 Red Herring Global 100 award winner. (Fri, 22 Jan 2010 16:00:00 GMT)
Movers & Shakers
Pinot resigned effective Jan. 15 to pursue other career opportunities, Tyrian said in a statement. Vamos replaces him effective Feb. 2. Vamos most recently was a group commercial manager for Mini-Tankers Australia. (Fri, 22 Jan 2010 16:45:32 GMT)
New Chips With Rare Variants Will Drive Growth in SNP Market
NEW YORK, NY--(Marketwire - 01/22/10) - A setback in the scientific basis for SNP (single nucleotide polymorphisms) analysis may turn out to be a blessing in disguise for makers of genotyping equipment, reagents and software, according to Kalorama Information. The medical market research publisher foresees double-digit growth in equipment sales, chemicals and software as more refined chips enter ... (Fri, 22 Jan 2010 16:59:00 GMT)
New Chips With Rare Variants Will Drive Growth in SNP Market
NEW YORK, NY--(Marketwire - January 22, 2010) - A setback in the scientific basis for SNP (single nucleotide polymorphisms) analysis may turn out to be a blessing in disguise for makers of genotyping equipment, reagents and software, according to Kalorama Information. The medical market research publisher foresees double-digit growth in equipment sales, chemicals and software as more refined ... (Fri, 22 Jan 2010 17:01:47 GMT)
Sunflower genome to pave way for sustainable agriculture
Washington: Researchers are creating a reference genome for the sunflower family that would enable the breeding of crops better suited to their growing environment and consumers tastes. (Fri, 22 Jan 2010 17:18:30 GMT)
Everyday Habits for a Healthy Heart
American Heart Month in February is the perfect time to initiate lifestyle changes that can help lower your risk of cardiovascular diseases, the world's largest killers. Fitness expert Karin Richards provides simple lifestyle changes that can keep your heart healthy. (Fri, 22 Jan 2010 18:43:51 GMT)
In Brief This Week: Life Technologies; Febit; Caris Diagnostics; Thermo Fisher Scientific; Empire Genomics; Beckman ...
NEW YORK (GenomeWeb News) – Life Technologies said this week that the Federal Bureau of Investigation has approved use of the Applied Biosystems MiniFiler PCR Amplification Kit in the National DNA Index System (NDIS). The MiniFiler is designed to obtain results from compromised and degraded samples, and has been used in cold cases, missing person cases, exonerations, and historical and ... (Fri, 22 Jan 2010 19:45:32 GMT)
People In The News
NEW YORK (GenomeWeb News) - Vance Vanier will take over the president and CEO positions at Navigenics. Vanier started at Navigenics in 2008 and was serving as chief medical officer of the consumer genomics firm. Before joining Navigenics, he was a partner at Mohr Davidow Ventures. (Fri, 22 Jan 2010 19:45:42 GMT)
Liotta, Petricoin Using Protein Array Technology to Test Gleevec for Colorectal Cancer
Lance Liotta and Emanuel Petricoin have launched a clinical trial using technology they developed to test whether the cancer drug Gleevec can be used to treat colorectal cancer, in what they said it is one of the first applications of proteomics technology for personalized medicine. (Fri, 22 Jan 2010 20:45:44 GMT)
PerkinElmer Sues Life Tech, MDS, MDS Analytical Technologies Alleging Mass Spec IP Infringement
PerkinElmer is suing Life Technologies, MDS, and MDS Analytical Technologies, alleging they are infringing five patents held by PerkinElmer for certain mass spectrometry technologies. (Fri, 22 Jan 2010 21:00:32 GMT)
HUPO Launching Quantitative Test Sample Study in Late Summer, Advances Human Proteome Project
The Human Proteome Organization hopes to launch its second protein test sample study at this year's annual conference in the fall, and is developing an action plan for the next phase of the organization's goal to create a human proteome map, its secretary general told ProteoMonitor this week, furthering along two of HUPO's most ambitious projects in recent years. (Fri, 22 Jan 2010 21:01:33 GMT)
Combo Test Might Spot Ovarian Cancer Early
Title: Combo Test Might Spot Ovarian Cancer Early Category: Health News Created: 1/21/2010 2:10:00 PM Last Editorial Review: 1/22/2010 (Fri, 22 Jan 2010 21:33:43 GMT)
Downloads and Upgrades
The new release includes 514,212 sequence entries, comprising 180,900,945 amino acids abstracted from 186,149 references. UniProt also announced that cross-references have been added to eggnog (Evolutionary Genealogy of Genes: Non-supervised Orthologous Groups), a database of orthologous groups of genes. (Fri, 22 Jan 2010 21:45:32 GMT)
Personal genomics is getting serious: Counsyl emerging from stealth mode [Genetic Future]
Disclaimer: my wife and I have both received and used free testing kits from Counsyl. Counsyl is a rather enigmatic player in the personal genomics field: apart from a brief mention in Steven Pinker's excellent NY Times piece over a year ago and an even briefer post on a Newsweek blog late last year, the company has been in determined stealth mode for much of the last two years. All that was ... (Fri, 22 Jan 2010 22:47:49 GMT)
Complete Genomics receives 2009 Red Herring Global 100 award
Complete Genomics Inc., a third-generation human genome sequencing company, today announced that it has been selected as a 2009 Red Herring Global 100 award winner. The company was also recognized as a 2009 Red Herring North America 100 award winner earlier last year. (Sat, 23 Jan 2010 05:10:43 GMT)
QuantiScientifics, LLC (Irvine, CA) will Introduce the A2 Multiplex Assay System at LabAutomation 2010
QuantiScientifics, LLC Aquired the A2 Business from Beckman Coulter, Inc. and will relaunch the product this year at LabAutomation. (Sat, 23 Jan 2010 07:00:00 GMT)
Kalorama report predicts double-digit growth in SNP market
A setback in the scientific basis for SNP (single nucleotide polymorphisms) analysis may turn out to be a blessing in disguise for makers of genotyping equipment, reagents and software, according to Kalorama Information. (Sat, 23 Jan 2010 08:25:23 GMT)
Diagnosis Of Early-Stage Ovarian Cancer By Ultrasound Plus Proteomic Blood Analyses
Noninvasive contrast-enhanced ultrasound imaging, combined with proteomic analyses of blood samples may help physicians identify early-stage ovarian cancer and save the lives of many women, according to an article published in the February issue of the American Journal of Roentgenology. Proteomics is the study of proteins, particularly their structure and function. Ovarian cancer is the fifth ... (Sat, 23 Jan 2010 11:30:49 GMT)
UniProt, European Bioinformatics Institute, Swiss Institute of Bioinformatics, Protein Information Resource, Thermo ...
The UniProt consortium consisting of the European Bioinformatics Institute , the Swiss Institute of Bioinformatics and the Protein Information Resource announced on Monday the launch of UniProt Release 2.5, a catalog of information on proteins. Monday. (Sat, 23 Jan 2010 13:15:32 GMT)
Researchers Sequence Genome of Mosquito That Carries Yellow, Dengue Fevers
An earlier version of this report erroneously omitted the Broad Institute’s participation in the study. (Sat, 23 Jan 2010 13:15:52 GMT)
Weekly Guru Bargains Highlights: PCS, ISIS, LEAP, UHS, CNW
By guruyt. Last week's top five guru bargain stocks were MetroPCS Communications Inc, Isis Pharmaceuticals Inc, Leap Wireless International Inc, Universal Health Services Inc, and Con-way Inc. According to GuruFocus updates, these stocks have declined the most since Gurus have bought. Read more » » (Sun, 24 Jan 2010 05:58:58 GMT)
Startups hold key to economic growth in Rochester
Through much of the 20th century, industries such as men's clothing and manufacturers including Eastman Kodak and Bausch + Lomb created fortunes for investors and careers for legions of workers. But today, new businesses are essential to economic growth. (Sun, 24 Jan 2010 10:05:38 GMT)
Will Personalized Medicine Kill Health Insurance?
An article at VentureBeat considers the future of privatized health insurance through the eyes of a world where personal genomics has become the norm. (Sun, 24 Jan 2010 13:16:45 GMT)
Genomics boosts brain-cancer work
Molecular findings start to open up avenues of diagnosis and treatment. (Sun, 24 Jan 2010 15:42:59 GMT)
Researchers trace effects of genetic defect in myotonic muscular dystrophy
( University of California - Santa Cruz ) Research on the genetic defect that causes myotonic muscular dystrophy has revealed that the mutation disrupts an array of metabolic pathways in muscle cells through its effects on two key proteins. (Sun, 24 Jan 2010 18:21:20 GMT)
Illuminating protein networks in 1 step
( University of Chicago Medical Center ) A new assay capable of examining hundreds of proteins at once and enabling new experiments that could dramatically change our understanding of cancer and other diseases has been invented by a team of University of Chicago scientists. Described today in the journal Nature Methods, the new micro-western arrays combine the specificity of the popular "Western ... (Sun, 24 Jan 2010 18:21:40 GMT)
Illuminating Protein Networks in One Step
A new assay capable of examining hundreds of proteins at once and enabling new experiments that could dramatically change our understanding of cancer and other diseases has been invented by a team of University of Chicago scientists. (Sun, 24 Jan 2010 18:39:28 GMT)
Researchers trace effects of genetic defect in myotonic muscular dystrophy
Research on the genetic defect that causes myotonic muscular dystrophy has revealed that the mutation disrupts an array of metabolic pathways in muscle cells through its effects on two key proteins. A study published in Nature Structural & Molecular Biology shows that the loss of a single protein accounts for most of the molecular abnormalities associated with the disease, while loss of a second ... (Sun, 24 Jan 2010 20:13:02 GMT)
Researchers trace effects of genetic defect in myotonic muscular dystrophy
Research on the genetic defect that causes myotonic muscular dystrophy has revealed that the mutation disrupts an array of metabolic pathways in muscle cells through its effects on two key proteins. (Sun, 24 Jan 2010 23:24:55 GMT)
Illuminating protein networks in one step
A newly developed assay is capable of examining hundreds of proteins at once and enabling new experiments that could dramatically change our understanding of cancer and other diseases. The new micro-western arrays combine the specificity of the popular "Western blot" protein assay with the large scale of DNA microarrays. (Sun, 24 Jan 2010 23:25:15 GMT)
Exploring Differences in Epialleles
While multiple international projects have been underway for some time to map the epigenome, Vardhman Rakyan knows what a daunting task it will be to put all this information in the context of disease susceptibility. (Mon, 25 Jan 2010 00:45:32 GMT)
Blog - Decode Ditches Drug Development
The revamped version of the company will focus on genetic research and diagnostics. (Mon, 25 Jan 2010 01:19:57 GMT)
No-one hurt in Waite campus blast
A chemical explosion is being investigated at Adelaide University's Waite campus at Urrbrae. (Mon, 25 Jan 2010 02:45:26 GMT)
Guru Stocks at 52-Week Low: GME, MYGN, PCS, EM, TBH
By guruyt. According to GuruFocus updates, these Guru stocks have reached their 52-week lows. Read more » » (Mon, 25 Jan 2010 03:27:36 GMT)
Erbitux improves survival of mCRC patients with KRAS wild-type tumors
Merck Serono, a division of Merck KGaA, Darmstadt, Germany, today announced that Erbitux® (cetuximab) provided an improvement in overall survival (OS) when added to the standard 1st-line FOLFIRI chemotherapy regimen for metastatic colorectal cancer (mCRC) patients with KRAS wild-type tumors in the CRYSTAL study. (Mon, 25 Jan 2010 05:07:26 GMT)
Value of sexual reproduction versus asexual reproduction
Living organisms have good reason for engaging in sexual, rather than asexual, reproduction according to scientists. (Mon, 25 Jan 2010 05:12:26 GMT)
Effects of genetic defect in myotonic muscular dystrophy revealed
London, Jan 25 : In a new research on the genetic defect behind myotonic muscular dystrophy, scientists have found that the mutation disrupts an array of metabolic pathways in muscle cells through its effects on two key proteins. (Mon, 25 Jan 2010 06:33:34 GMT)
DiaGenic, Ferrer inCode sign distribution pact for ADtect test for early diagnosis of Alzheimer's disease
DiaGenic ASA and Ferrer inCode announced that they have signed a distribution agreement for the blood-based ADtect test for early diagnosis of Alzheimer’s disease covering a total of 32 countries. (Mon, 25 Jan 2010 06:36:25 GMT)
GSK Invites Academic Collaboration in Singapore, Announces Open Innovation Agenda
Bio-IT World | SINGAPORE—GlaxoSmithKline launched the GlaxoSmithKline-Singapore Academic Centre of Excellence (ACE) on Monday, with a two-day ACE symposium. The symposium follows closely on last Wednesday’s announcement by Andrew Witty, chief executive of GlaxoSmithKline, of an open innovation strategy, much of which so far is targeted at developing drugs and a vaccine for malaria. (Mon, 25 Jan 2010 08:44:54 GMT)
Mark McGowan Joins CombiMatrix Board of Directors
MUKILTEO, Wash. -- CombiMatrix Corporation today announced the appointment of Mark McGowan to the company's Board of Directors. Mr. McGowan's appointment became effective January 21, 2010. (Mon, 25 Jan 2010 11:00:00 GMT)
Ingenuity Systems appoints SeouLin Bioscience as exclusive distributor of IPA software in South Korea
Ingenuity Systems, the leading provider of information solutions for life science researchers, today announced the appointment of SeouLin Bioscience Co., Ltd. as the exclusive distributor of IPA in South Korea. (Mon, 25 Jan 2010 11:52:46 GMT)
Arrayit Corporation's Proteomic Biomarkers Clear the Way for Pre-Symptomatic Detection of Ovarian Cancer and Other ...
SUNNYVALE, CA--(Marketwire - 01/25/10) - Arrayit Corporation (OTC.BB: ARYC - News ), a leading manufacturer of products and services for disease prevention, treatment and cure, announces that Arrayit's new proteomic biomarkers will allow doctors to provide patients with a true pre-symptomatic diagnosis for Ovarian Cancer. Similar biomarkers are being developed to discover if patients are pre ... (Mon, 25 Jan 2010 12:00:00 GMT)
Arrayit Corporation's Proteomic Biomarkers Clear the Way for Pre-Symptomatic Detection of Ovarian Cancer and Other ...
Tests Will Provide Patients With an Early Diagnosis Increasing the Opportunity for Curative Measures (Mon, 25 Jan 2010 12:06:11 GMT)
Jt Indo-German workshop on bioinformatics begins
Amritsar, Jan 25 (PTI) A joint Indo-German workshop on "Bioinformatics in Human Genetics: Mutations, Microarray Analysis & Ontologies" began today at the Guru Nanak Dev University here. (Mon, 25 Jan 2010 13:20:46 GMT)
Researchers Trace Effects Of Genetic Defect In Myotonic Muscular Dystrophy
Research on the genetic defect that causes myotonic muscular dystrophy has revealed that the mutation disrupts an array of metabolic pathways in muscle cells through its effects on two key proteins. A study published in Nature Structural & Molecular Biology shows that the loss of a single protein accounts for most of the molecular abnormalities associated with the disease, while loss of a second ... (Mon, 25 Jan 2010 13:31:49 GMT)
Researchers track evolution and spread of drug-resistant bacteria across hospitals and continents
( Rockefeller University ) Using high resolution genome sequencing, scientists have tracked a deadly strain of multidrug-resistant Staphylococcus aureus as it traveled between South America, Europe and Southeast Asia. The new technique provides an unprecedented view of how MRSA evolved over decades and across entire continents, as well as on the short timescale of a few weeks within a hospital ... (Mon, 25 Jan 2010 14:06:10 GMT)
Researchers at Signature Genomics Attribute Diverse Spectrum of Brain and Facial Anomalies to Genetic Regions ...
SPOKANE, Wash.----Researchers at Signature Genomic Laboratories, which performs diagnostic genetic testing of chromosome abnormalities in individuals with unexplained physical and developmental disabilities, recently characterized a broad spectrum of facial and brain anomalies in individuals with chromosome aberrations associated with holoprosencephaly. (Mon, 25 Jan 2010 14:07:00 GMT)
Ultrasound plus proteomic blood analyses may help physicians diagnose early-stage ovarian cancer
Noninvasive contrast-enhanced ultrasound imaging, combined with proteomic analyses of blood samples may help physicians identify early-stage ovarian cancer and save the lives of many women, according to a new article. (Mon, 25 Jan 2010 15:12:46 GMT)
Genomics Lawsuit Spurs Drama
A dramatic lawsuit hits the gene sequencing world; bullishness on Forest Labs and doubts about journ (Mon, 25 Jan 2010 15:30:47 GMT)
Research and Markets: This Essential Report on U.S. Epigenetics Markets is Now Available
DUBLIN----Research and Markets has announced the addition of Frost & Sullivan's new report "U.S. Epigenetics Markets" to their offering. (Mon, 25 Jan 2010 16:10:00 GMT)
Effects Of Genetic Defect In Myotonic Muscular Dystrophy Traced
Research on the genetic defect that causes myotonic muscular dystrophy has revealed that the mutation disrupts an array of metabolic pathways in muscle cells through its effects on two key proteins. (Mon, 25 Jan 2010 16:11:21 GMT)
Researchers Track Evolution And Spread Of Drug-Resistant Bacteria
An international team of researchers has used high resolution genome sequencing to track a particularly virulent strain of MRSA as it traveled between South America, Europe and Southeast Asia. (Mon, 25 Jan 2010 16:11:51 GMT)
New Generation Of Genomics Sequencing Systems Raise Target Stock Prices By Leading Medical Industry Analyst
67 WALL STREET, New York - January 25, 2010 - The Wall Street Transcript has just published its Medical Research, Diagnostic Substances, Life Science Tools Report offering a timely review of the sector to serious investors and industry executives. This 35 page feature contains expert industry commentary through in-depth interviews with public company CEOs, Equity Analysts and Money Managers. The ... (Mon, 25 Jan 2010 16:47:00 GMT)
HiSeq 2000 Genomics System Begins New Generation Of Innovation In DNA Sequencing Sector Of Biotech And Medical ...
67 WALL STREET, New York - January 25, 2010 - The Wall Street Transcript has just published its Medical Research, Diagnostic Substances, Life Science Tools Report offering a timely review of the sector to serious investors and industry executives. This 35 page feature contains expert industry commentary through in-depth interviews with public company CEOs, Equity Analysts and Money Managers. The ... (Mon, 25 Jan 2010 16:53:00 GMT)
REvolution Computing Names Robert Gentleman and Donald Nickelson to Board
PALO ALTO, Calif.----REvolution Computing, the leading commercial provider of software and support for the open source “R” statistical computing language, announced the appointment of R co-creator Robert Gentleman and investment-banking veteran Donald Nickelson to its board of directors. (Mon, 25 Jan 2010 17:00:00 GMT)
Into the Personal Genomics Fray
Counsyl, a Stanford University start-up, has announced its Universal Genetic Test that allows prospective parents to determine whether their child would be at risk for more than 100 genetic diseases. (Mon, 25 Jan 2010 17:00:53 GMT)
Discovery Links Genes to Pancreatic Cancer
MONDAY, Jan. 25 (HealthDay News) -- Researchers have identified four regions of the human genome that predict a heightened risk of pancreatic cancer as a result of what they describe as the biggest-ever sweep of the genome for genes related to the disease. (Mon, 25 Jan 2010 17:03:09 GMT)
Market Pulse Breaking News Alert for Monday, January 25, 2010: ARYC -- Arrayit Corporation's Proteomic Biomarkers ...
ATLANTA, GA--(Marketwire - 01/25/10) - Market Pulse News Alert for this AM, Stocks to Watch are: Arrayit Corporation (OTC.BB: ARYC - News ), Apple Inc. (NASDAQ: AAPL - News ), Medifast Inc. (NYSE: MED - News ) and Conexant Systems Inc. (NASDAQ: CNXT - News ). Investors need to be watching Arrayit Corporation (OTC.BB: ARYC - News ) this AM! Arrayit Corporation is engaged in the development ... (Mon, 25 Jan 2010 17:51:00 GMT)
Arrayit Corporation’s Proteomic Biomarkers Provide Real Pre-Symptomatic Detection Of Ovarian Cancer And Other Major ...
Arrayit Corporation, (OTCBB: ARYC ) , a leading manufacturer of products and services for disease prevention, treatment and cure, announces that Arrayit’s new proteomic biomarkers will allow doctors to provide patients with a true pre-symptomatic diagnosis for Ovarian Cancer. (Mon, 25 Jan 2010 17:56:32 GMT)
Market Pulse Breaking News Alert for Monday, January 25, 2010: ARYC -- Arrayit Corporation's Proteomic Biomarkers ...
NOTE TO EDITORS: The Following Is an Investment Opinion Being Issued by Market Pulse. (Mon, 25 Jan 2010 18:05:52 GMT)
Project seeks genetic basis of childhood cancer
Researchers announced a new project on Monday to sequence all the genes in childhood tumors to try to discover previously unknown causes of cancer. (Mon, 25 Jan 2010 19:13:26 GMT)
Overcoming Taxane Resistance in Cancer
Proteomics study reveals a protein that, when suppressed, makes cancers more susceptible to chemotherapy (Mon, 25 Jan 2010 20:00:00 GMT)
Ingenuity Systems Taps SeouLin Bioscience as Distributor for South Korea
Ingenuity Systems said this week that SeouLin Bioscience will serve as the exclusive distributor of IPA in South Korea. (Mon, 25 Jan 2010 21:00:53 GMT)
UF's EPI poised to fight tomorrow's diseases
By DIANE CHUN Staff writer Within these walls, researchers are preparing to do battle with the next wave of infectious diseases that could plague our times. (Photo by Tricia Coyne/The Gainsville Sun) (Tue, 26 Jan 2010 00:26:03 GMT)
UCSF conference to focus on therapeutics of the future
Some of the leading scientists in bioengineering, nanotechnology and pharmaco-genomics will gather on Tuesday, January 26, 2010 to discuss how to harness the tools of these emerging fields to develop new diagnostics and treatments for complex diseases. (Tue, 26 Jan 2010 01:42:47 GMT)
Genetic research: The fight against disease gets personal
Advances in genetic research mean that cures for killer diseases could soon be tailored to individual patients. (Tue, 26 Jan 2010 07:18:15 GMT)
Frontline defense
By Diane Chun Staff writer The University of Florida is home to a new $60 million research facility, prepared to function as an early warning system for emerging diseases and linking investigators around the world. (Tricia Coyne/ Staff) (Tue, 26 Jan 2010 11:13:54 GMT)
caprotec bioanalytics Announces Commercial Launch of Three New caproKits(TM) for Applications in Proteomics and Drug ...
caprotec bioanalytics announced today the commercial launch of three new caproKits, enabling the discovery, identification and characterization of proteins belonging to the groups of metallo-proteases, histon-deacetylases and GDP/GTP binding proteins. (Tue, 26 Jan 2010 11:30:00 GMT)
MDRNA, Inc. Issued Patent for the Use of Nucleic Acids to Treat Cancer
BOTHELL, WA--(Marketwire - 01/26/10) - MDRNA, Inc. (NASDAQ: MRNA - News ), a leading RNAi-based drug discovery and development company, today announced that the State Intellectual Property Office of the People's Republic of China (PRC) has issued a Notification of Granting Patent Rights for PRC 200480018784 which includes the use of nucleic acids, e.g., an siRNA, for the treatment of cancer. The ... (Tue, 26 Jan 2010 13:00:00 GMT)
454 Life Sciences Offers Simplified Sequencing Workflow with New Automation Solution for the Genome Sequencer FLX System
BRANFORD, Conn.----454 Life Sciences announced today the launch and immediate availability of the new REM e System, a robotic accessory module for liquid handling systems which enables complete automation of emPCR enrichment in the GS FLX Titanium workflow. (Tue, 26 Jan 2010 13:00:00 GMT)
MDRNA, Inc. Issued Patent for the Use of Nucleic Acids to Treat Cancer
MDRNA IP Estate Extends Into Asia (Tue, 26 Jan 2010 13:08:39 GMT)
caprotec bioanalytics Announces Commercial Launch of Three New caproKits(TM) for Applications in Proteomics and Drug ...
BERLIN and BURLINGTON, Mass., Jan. (Tue, 26 Jan 2010 14:08:46 GMT)
Evolution And Spread Of Drug-Resistant Bacteria Tracked Across Hospitals And Continents
An international team of researchers has used high resolution genome sequencing to track a particularly virulent strain of MRSA as it traveled between South America, Europe and Southeast Asia. The findings shed light on how these deadly bacteria are able to spread from patient to patient in a single hospital and, on a larger scale of geography and time, between countries and entire continents... (Tue, 26 Jan 2010 14:17:00 GMT)
Press Release
454 Life Sciences announced today the launch and immediate availability of the new REM e System, a robotic accessory module for liquid handling systems which enables complete automation of emPCR enrichment in the GS FLX Titanium workflow. (Tue, 26 Jan 2010 15:10:15 GMT)
Sequencing Study Reveals Invasive Bacteria Epidemic Patterns
NEW YORK (GenomeWeb News) – In a paper scheduled to appear online this week in the Proceedings of the National Academy of Sciences , an international research team reported that they have sequenced and compared the genomes of nearly 100 group A Streptococcus strains — bacteria that can cause a severe form of necrotizing fasciitis, also known as flesh-eating disease — identifying features in the ... (Tue, 26 Jan 2010 16:00:32 GMT)
Chicago Cancer Genome Project Clinically Characterizing Tumors; May Work with Complete Genomics
One year into a three-year, 1,000-tumor sequencing project, researchers at the University of Chicago's Cancer Genome Project have sequenced the transcriptomes of over 100 tumors and cancer cell lines on the Illumina Genome Analyzer, and plan to move into exon capture and possibly collaborate with Complete Genomics for whole-genome sequencing, the Chicago researchers told In Sequence last week. (Tue, 26 Jan 2010 16:45:32 GMT)
Labcyte Expands Acoustic Dispensing and Launches Into New Markets
SUNNYVALE, Calif.----Today Labcyte introduced two pre-calibrated liquid class packages for use with its award-winning Echo® acoustic dispensers and POD™ 810 plate assemblers, which move liquids with sound. (Tue, 26 Jan 2010 17:00:00 GMT)
Baby bellies
Dirty diapers help map the infant intestinal microbiota (Tue, 26 Jan 2010 17:07:02 GMT)
People in the News
Vanier started at Navigenics in 2008 and was serving as chief medical officer of the consumer genomics firm. Before joining Navigenics, he was a partner at Mohr Davidow Ventures . He also is a clinical faculty member at Stanford University Medical Center . (Tue, 26 Jan 2010 17:45:42 GMT)
Illumina to Submit Cytogenetics Package to FDA, Commits to Using Arrays in Dx
Marking a shift in strategy , Illumina plans to submit its iScan system and accompanying arrays and software to the US Food and Drug Administration for clearance, according to a company official. (Tue, 26 Jan 2010 18:00:32 GMT)
Overcoming taxane resistance in cancer
Taxanes have become front-line therapy for a variety of metastatic cancers, but resistance can develop, a frequent problem in breast, ovarian, prostate and other cancers. Now, researchers at Children's Hospital Boston report a protein involved in taxane resistance that could potentially be targeted with drugs, making a cancer more susceptible to chemotherapy, and could potentially also serve as ... (Tue, 26 Jan 2010 19:27:38 GMT)
Mammoth Achievement: Researchers at the forefront of molecular biology
Forget Jurassic Park. By successfully sequencing the DNA of a long-extinct species, Stephan Schuster and Webb Miller have helped push back the boundaries of molecular biology. (Tue, 26 Jan 2010 20:13:03 GMT)
Source BioScience Purchases Two Illumina GAIIx; Plans to Install HiSeq 2000 this Year
UK service provider Source BioScience has purchased two Illumina Genome Analyzer IIx systems and plans to bring the firm's HiSeq 2000 technology in house later this year, the company said this week. (Tue, 26 Jan 2010 20:15:33 GMT)
NIDDK to Fund Molecular Hematology Centers, Cores
NEW YORK (GenomeWeb News) – The National Institute of Diabetes and Digestive and Kidney Diseases will grant $4.6 million in 2010 to fund four hematology research centers that will study, and serve as a resource for other studies of, hematologic diseases. (Tue, 26 Jan 2010 20:30:32 GMT)
Advances in Cancer Detection Featured in Microfluidics Journal
Building upon novel technology developed while working on Homeland Security projects at Sandia National Laboratories (SNL) as well as from his biomedical graduate student days, a Virginia Tech assistant professor of biomedical engineering is now creating unique microsystems that are showing considerable promise for the detection of cancer and for the study of the progression of this disease. (Tue, 26 Jan 2010 20:40:43 GMT)
Overcoming taxane resistance in cancer
Taxanes, a group of cancer drugs that includes paclitaxel (Taxol(R)) and docetaxel (Taxotere(R)), have become front-line therapy for a variety of metastatic cancers. But as with many chemotherapy agents, resistance can develop, a frequent problem in breast, ovarian, prostate and other cancers. Now, cancer researchers at Children's Hospital Boston report a protein previously unknown to be ... (Tue, 26 Jan 2010 20:42:32 GMT)
Philips, BioMerieux to Develop Biochips for Cardiovascular Diseases
Royal Philips Electronics and bioMérieux plan to jointly develop fully automated handheld diagnostic biochips for hospital use that can be deployed at the point of care. The firms are aiming for eventual adoption of their chips in critical care settings within hospitals. (Tue, 26 Jan 2010 20:46:02 GMT)
Overcoming taxane resistance in cancer
Taxanes have become front-line therapy for a variety of metastatic cancers, but resistance can develop, a frequent problem in breast, ovarian, prostate and other cancers. Now, researchers report a protein involved in taxane resistance that could potentially be targeted with drugs, making a cancer more susceptible to chemotherapy, and could potentially also serve as a biomarker in monitoring ... (Tue, 26 Jan 2010 21:25:53 GMT)
Cause of myotonic muscular dystrophy traced
Research on the genetic defect that causes myotonic muscular dystrophy has revealed that the mutation disrupts an array of metabolic pathways in muscle cells through its effects on two key proteins. (Tue, 26 Jan 2010 22:22:13 GMT)
Overcoming Taxane Resistance In Cancer
Proteomics study reveals a protein that, when suppressed, makes cancers more susceptible to chemotherapyTaxanes, a group of cancer drugs that includes paclitaxel (Taxol®) and docetaxel (Taxotere®), have become front-line therapy for a variety of metastatic cancers. (Tue, 26 Jan 2010 23:10:11 GMT)
Algae as biofuel still rough around the edges
Sources of nutrients, carbon dioxide can make or break this potential renewable fuel heavyweight (Tue, 26 Jan 2010 23:32:51 GMT)
Bioinformatics opens new realms in biology
SHAH ALAM: Development in science and technology has led to the creation of many new things to benefit mankind. (Wed, 27 Jan 2010 00:17:21 GMT)
Bioinformatics opens new realms in biology
It also creates an alternative to the road of new discoveries, utilising existing know-how and knowledge. One such field which is now in the forefront is bioinformatics. Bioinformatics, coined from th... (Wed, 27 Jan 2010 01:06:03 GMT)
Bioinformatics opens new realms in biology
SHAH ALAM: Development in science and technology has led to the creation of many new things to benefit mankind. (Wed, 27 Jan 2010 01:17:17 GMT)
Dr. Carol Moreno-Quinn Joins PhysioGenix's Science Advisory Team
PhysioGenix annonces a preclinical collaboration with Dr. Carol Moreno-Quinn. (Wed, 27 Jan 2010 07:00:00 GMT)
Dr. Carol Moreno-Quinn Joins PhysioGenix's Science Advisory Team
PhysioGenix announces a preclinical collaboration with Dr. Carol Moreno-Quinn. (Wed, 27 Jan 2010 07:00:00 GMT)
Researchers At Signature Genomics Attribute Diverse Spectrum Of Brain And Facial Anomalies To Genetic Regions ...
Researchers at Signature Genomic Laboratories, which performs diagnostic genetic testing of chromosome abnormalities in individuals with unexplained physical and developmental disabilities, recently characterized a broad spectrum of facial and brain anomalies in individuals with chromosome aberrations associated with holoprosencephaly. Holoprosencephaly is a disorder in which the forward-most ... (Wed, 27 Jan 2010 07:31:10 GMT)
Nacalai USA to distribute TriLink's modified nucleic acid products in Japan, Singapore, South Korea & Taiwan
TriLink BioTechnologies (TriLink), has entered into an agreement with Nacalai USA, Inc., a San Diego based manufacturing and marketing company, for the distribution of TriLink’s modified nucleic acid products in Japan, Singapore, South Korea and Taiwan. (Wed, 27 Jan 2010 09:36:25 GMT)
New discovery may help overcome taxane resistance in cancer
Washington, Jan 27 : Scientists at Children's Hospital Boston have discovered a protein involved in taxane resistance, a group of cancer drugs that includes paclitaxel (Taxol) and docetaxel (Taxotere) and have become front-line therapy for a variety of metastatic cancers. (Wed, 27 Jan 2010 10:09:47 GMT)
Facial and brain anomalies in holoprosencephaly related chromosome aberrations characterized
Researchers at Signature Genomic Laboratories, which performs diagnostic genetic testing of chromosome abnormalities in individuals with unexplained physical and developmental disabilities, recently characterized a broad spectrum of facial and brain anomalies in individuals with chromosome aberrations associated with holoprosencephaly. (Wed, 27 Jan 2010 11:07:26 GMT)
Proteomics study reveals protein suppression makes cancers more susceptible to chemotherapy
Taxanes, a group of cancer drugs that includes paclitaxel (Taxol-) and docetaxel (Taxotere-), have become front-line therapy for a variety of metastatic cancers. But as with many chemotherapy agents, resistance can develop, a frequent problem in breast, ovarian, prostate and other cancers. (Wed, 27 Jan 2010 11:23:16 GMT)
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