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Orexigen's Empatic Phase 2b results exhibit meaningful weight loss
Orexigen® Therapeutics, Inc. today announced that its 24-week, Phase 2b trial for Empatic(TM) (bupropion SR/zonisamide SR), the Company's second late stage investigational combination drug for the treatment of obesity, met its primary efficacy endpoint by demonstrating statistically significantly greater weight loss for both Empatic doses compared to monotherapies and placebo. (Thu, 01 Oct 2009 06:47:15 GMT)
OICR completes evaluation of NEB's new reagents for use with the Illumina Genome Analyzer
Dr. John McPherson, Platform Leader, Cancer Genomics and High-Throughput Screening, and Dr. Kamran Shazand, Project Manager, of the Ontario Institute for Cancer Research (OICR) led a team of scientists who have completed a thorough evaluation of the NEBNext(TM) DNA Sample Prep Reagents for use with OICR's Illumina® Genome Analyzer II. (Thu, 01 Oct 2009 08:57:41 GMT)
The National Cancer Institute Selects Integral Molecular to Map Epitopes on Cancer Biomarkers using Shotgun ...
PHILADELPHIA----Integral Molecular, Inc. has been selected by the National Cancer Institute to map epitopes for monoclonal antibodies directed against cancer biomarkers. Protein targets of interest to the Clinical Cancer Proteomics community will be analyzed using Shotgun Mutagenesis Mapping technology to identify amino acids that are essential for antibody binding, allowing the discovery and ... (Thu, 01 Oct 2009 12:00:00 GMT)
NCI selects Integral Molecular to map epitopes for monoclonal antibodies
Integral Molecular, Inc. has been selected by the National Cancer Institute (NCI) to map epitopes for monoclonal antibodies directed against cancer biomarkers. Protein targets of interest to the Clinical Cancer Proteomics community will be analyzed using Shotgun Mutagenesis Mapping technology to identify amino acids that are essential for antibody binding, allowing the discovery and ... (Thu, 01 Oct 2009 13:08:34 GMT)
Researchers present MRAM-based FPGA architecture
Researchers at the Montpellier Laboratory of Informatics, Robotics and Microelectronics, in France, claimed they have developed a FPGA circuit based on non volatile resistive memory cell. (Thu, 01 Oct 2009 14:51:32 GMT)
New Products
Agilent Technologies this week launched the Agilent Complex Proteomics Standard for the validation of mass spectrometry-based workflows for protein identification. (Thu, 01 Oct 2009 15:35:18 GMT)
Related Articles
KINAXO Biotechnologies has added KinAffinity to its service portfolio. KinAffinity provides invaluable information about a kinase inhibitor’s selectivity in a cell or tissue of interest. (Thu, 01 Oct 2009 15:43:34 GMT)
Cold Spring Harbor Protocols features RNA analysis methods
( Cold Spring Harbor Laboratory ) Techniques for isolating RNA and for uncovering its interactions with proteins have taken on new importance as many laboratories define the roles of specific RNAs in the cell. The October issue of "Cold Spring Harbor Protocols" features two articles detailing methods for RNA analysis in zebrafish and the worm C. elegans. (Thu, 01 Oct 2009 15:48:01 GMT)
Genomics and Universal Healthcare
If the US enters the genomics-based medicine age without universal healthcare, Jeremy Grushcow at The Cross-Border Biotech Blog says that "it will exacerbate existing inequalities and create new ones we haven't even imagined." (Thu, 01 Oct 2009 16:05:28 GMT)
ANTI-ATKINS LOW PROTEIN DIET EXTENDS LIFESPAN IN FLIES
This study, appearing in Cell, provides details of a causal relationship between diet and mitochondrial function. It also provides the first genome-wide study of how proteins are translated under dietary restriction in any organism. Flies fed a low protein diet live longer because their mitochondria function better. The molecular mechanisms involved are conserved among many species making the ... (Thu, 01 Oct 2009 16:31:49 GMT)
'Anti-Atkins' low protein diet extends lifespan in flies
( Buck Institute for Age Research ) This study, appearing in Cell, provides details of a causal relationship between diet and mitochondrial function. It also provides the first genome-wide study of how proteins are translated under dietary restriction in any organism. Flied fed a low protein diet live longer because their mitochondria function better. The molecular mechanisms involved are ... (Thu, 01 Oct 2009 16:33:37 GMT)
Reportlinker Adds In Vitro Diagnostics US Market Report
Reportlinker.com announces that a new market research report is available in its catalogue. (Thu, 01 Oct 2009 16:34:00 GMT)
Human Proteome Organization honors PNNL scientist
( DOE/Pacific Northwest National Laboratory ) Laboratory and Battelle Fellow Dick Smith of the Department of Energy's Pacific Northwest National Laboratory has been recognized by the Human Proteome Organization for his many accomplishments in pioneering the development of proteomics tools. (Thu, 01 Oct 2009 16:53:20 GMT)
United States and Four Latin American Countries Partner to Battle Cancer
The United States National Cancer Institute (NCI), part of the National Institutes of Health, formalized bilateral partnerships this week with the governments of Argentina, Brazil, Mexico, and Uruguay, to accelerate progress against cancer in Hispanic populations in the United States and Latin America and improve cancer research. (Thu, 01 Oct 2009 17:29:53 GMT)
Longer-lived, healthier mice offer promise of drug treatments for age-related diseases
( Wellcome Trust ) Scientists have managed to extend the lifespan of mice by up to a fifth and reduce the number of age-related diseases the animals suffer. The research, which involved blocking a key molecular pathway, mimics the health benefits of reducing calorie intake and suggests that drug treatments for aging and age-related diseases are feasible. (Thu, 01 Oct 2009 18:33:57 GMT)
NCI Awards Integral Molecular $150K to ID Cancer Biomarkers
NEW YORK (GenomeWeb News) – Integral Molecular said today that the National Cancer Institute has awarded it a $150,000 contract to map epitopes for monoclonal antibodies directed against cancer biomarkers. (Thu, 01 Oct 2009 19:20:08 GMT)
UCSC breaks in new Extension Service in Silicon Valley
SANTA CLARA - Not unlike Silicon Valley itself, UC Santa Cruz Extension in Silicon Valley has downsized and rebranded to save money and meet the changing needs of its customers. (Thu, 01 Oct 2009 21:15:23 GMT)
Q&A: Nicola Ancona Compares Gene Set Enrichment Methods Head-to-Head
Gene set enrichment — interpreting gene expression data by analyzing it within the context of sets of genes in pathways rather than individual genes — has gained ground since researchers from the Broad Institute published their Gene Set Enrichment Analysis method in PNAS in 2005. (Thu, 01 Oct 2009 21:20:08 GMT)
HMS Brian Liu on Using Reverse-Capture Microarrays to Discover Disease Biomarkers
Position: Assistant professor of urology, Brigham and Women's Hospital, Harvard Medical School, since 1999. Background: Assistant professor, Department of Urology, Mount Sinai School of Medicine, 1990-1999. (Thu, 01 Oct 2009 22:05:23 GMT)
Different Organs Appear to Have Their Own Time Zones
SAN FRANCISCO, April 22 - The liver and heart beat to different time keepers, microarray technology has allowed researchers to learn. (Thu, 01 Oct 2009 22:05:54 GMT)
Krakow - Poland: An emerging R&D center for US companies
Krakow, in Poland, is emerging as a key R&D center for many US firms . . . (Fri, 02 Oct 2009 01:26:43 GMT)
Federal money boosts local health and social services non-profits
Update Friday: The University of Washington said this morning that it will use $25 million in Recovery Act funding from NIH to create a new Northwest Genomics Center and explore the origins of common heart, lung and blood disorders. (Fri, 02 Oct 2009 03:46:31 GMT)
UCSC opens leaner Extension program in Silicon Valley
SANTA CLARA -- Not unlike Silicon Valley itself, UC Santa Cruz Extension in Silicon Valley has downsized and rebranded to save money and meet the changing needs of its customers. (Fri, 02 Oct 2009 08:46:29 GMT)
Professor Jens Reich Received Carl Friedrich von Weizsäcker Award
Professor Jens Reich of the Max Delbrück Centrum for Molecular Medicine (MDC) Berlin-Buch has been honored with the Carl Friedrich von Weizsäcker Award of the National Academy of Sciences Leopoldina and the Stifterverband für die Deutsche Wissenschaft. (Fri, 02 Oct 2009 09:29:31 GMT)
ImmunoCellular Therapeutics' Antibody Shows Promise In Detecting Pancreatic And Lung Cancer In Serum Test
ImmunoCellular Therapeutics, Ltd. (OTCBB: IMUC), a clinical-stage biotechnology company that is developing immune-based therapies for the treatment of brain and other cancers, announced today results from its pilot study evaluating the cancer detection abilities of one of its lead monoclonal antibody product candidates, ICT-109. (Fri, 02 Oct 2009 10:11:16 GMT)
In Memoriam: Wesley Bonds, Pioneered High School Biotechnology Study
Wesley D. Bonds Jr., a former Yale research scientist who helped develop biotechnology instruction programs for high school students, died on Sept. 14. (Fri, 02 Oct 2009 12:35:33 GMT)
NCRR Grants Support 'Omics in Five States
NEW YORK (GenomeWeb News) – Several new grants from the National Center for Research Resources will provide tens of millions of support for resources and programs at various research institutions throughout the country, including funding for genomics, proteomics, bioinformatics, and educational development. (Fri, 02 Oct 2009 13:45:32 GMT)
NIH to Fund Resource Centers for Basic Aging Biology
NEW YORK (GenomeWeb News) - The National Institute of Aging plans to commit $4 million in 2010 to fund research centers that will focus on the basic biology of aging, including molecular and cell biology, genomics, proteomics, flow cytometry, bioimaging, and other ‘omics technlogies. (Fri, 02 Oct 2009 14:30:32 GMT)
Low Protein Diet Extends Lifespan In Flies
Diet boosts mitochondrial function, has implications for humansFlies fed an "anti-Atkins" low protein diet live longer because their mitochondria function better. (Fri, 02 Oct 2009 14:40:07 GMT)
Provincial funding for cancer institute
MONCTON, NB - The Graham government has announced $1 million for the Atlantic Cancer Research Institute (ACRI) at the Dumont Hospital in Moncton. Health Minister Mary Schryer is part of an ongoing commitment by the province to invest $5 million dollars in the institute over the next five years. (Fri, 02 Oct 2009 14:45:54 GMT)
Lifespan In Flies Extended By 'Anti-Atkins' Low Protein Diet
Flies fed an "anti-Atkins" low protein diet live longer because their mitochondria function better. The research, done at the Buck Institute for Age Research, shows that the molecular mechanisms responsible for the lifespan extension in the flies have important implications for human aging and diseases such as obesity, diabetes and cancer. (Fri, 02 Oct 2009 15:10:35 GMT)
Cold Spring Harbor Protocols Features RNA Analysis Methods
The study of RNA has long been the tool of choice for understanding where and when genes are expressed in a cell, tissue, or organism during development or under specific physiological or environmental conditions. (Fri, 02 Oct 2009 15:18:21 GMT)
'Anti-Atkins' Low Protein Diet Extends Lifespan In Flies
A new study provides details of a causal relationship between diet and mitochondrial function. It also provides the first genome-wide study of how proteins are translated under dietary restriction in any organism. Flied fed a low protein diet live longer because their mitochondria function better. The molecular mechanisms involved are conserved among many species -- making the research relevant ... (Fri, 02 Oct 2009 15:23:22 GMT)
Longer-lived, Healthier Mice Offer Promise Of Drug Treatments For Age-related Diseases
Scientists have managed to extend the lifespan of mice by up to a fifth and reduce the number of age-related diseases the animals suffer. The research, which involved blocking a key molecular pathway, mimics the health benefits of reducing calorie intake and suggests that drug treatments for aging and age-related diseases are feasible. (Fri, 02 Oct 2009 15:25:57 GMT)
Funding Update
This project will investigate the technical and commercial feasibility of a bioinformatic computing appliance based on FPGA technology. (Fri, 02 Oct 2009 18:00:32 GMT)
Jackson Lab Mulls Virtualization for Planned Bioinformatics Expansion, Will Hire New Staff
The Jackson Laboratory will use a $2.1 million grant from the National Center for Research Resources to expand the lab's computational facility and hire additional bioinformatics staff, the lab's CIO told BioInform this week. (Fri, 02 Oct 2009 18:15:34 GMT)
At OSU Conference, Hood Touts Family Sequencing as Way Forward for Personal Genomics
COLUMBUS, Ohio — The future of personal genomics, according to Leroy Hood, is not in randomly sequencing individuals, but sequencing the genomes of entire families. (Fri, 02 Oct 2009 18:45:32 GMT)
UW to explore genetic origins of common heart, lung, and blood diseases in federal project
The National Heart Lung and Blood Institute has given the UW two of six Large Scale DNA Sequencing grants. The economic stimulus funding will establish the Northwest Genomics Center and support work on the genetics of common, complex disorders. (Fri, 02 Oct 2009 18:49:20 GMT)
Grid-Funding Flows
With the National Science Foundation's recent $30.2 million award to keep the TeraGrid going, which also included $1 million to kick-start the Louisiana Optical Network Initiative and a $10.1 million grant to establish FutureGrid , researchers are going to be united via networks more than ever. (Fri, 02 Oct 2009 19:30:32 GMT)
Congress Passes Budget Patch
NEW YORK (GenomeWeb News) - The federal government’s Fiscal Year 2009 ended this week without a budget for 2010 being passed, so Congress passed a continuing resolution to keep money moving through the government while it completes its appropriations chores for the coming year. (Fri, 02 Oct 2009 19:45:32 GMT)
Dionex Closes ESA Biosciences' HPLC Assets Buy
NEW YORK (GenomeWeb News) - Dionex said today that it has closed its purchase of HPLC products, clinical assays, and lab services from ESA Biosciences' parent company, Magellan Biosciences, in a deal that was struck in mid-September. (Fri, 02 Oct 2009 19:45:42 GMT)
Montreal's Pharmacogenomics Centre Creates 38 TB Storage Scratch Pad for Next-Gen Sequencing Data
As part of its setup for a new Illumina Genome Analyzer, the bioinformatics team at the Montreal-based Pharmacogenomics Centre is ramping up its storage to 38 terabytes to handle data from upcoming sequencing projects by its 25 staff researchers and outside customers. (Fri, 02 Oct 2009 19:45:52 GMT)
EBI, Public Labs To Build Database Of DNA Microarray Expression Data
HINXTON, UK--At least nine public research institutions that generate gene expression information using DNA microarray technology have agreed to begin submitting their results to a new public archive. (Fri, 02 Oct 2009 23:05:29 GMT)
It's an Honor Just to Be Nominated
The folks behind the Benjamin Franklin Award for Open Access in the Life Sciences are accepting nominations now. (Fri, 02 Oct 2009 23:15:52 GMT)
Borrowing from the Movies
What does your spot on the list of authors for a paper mean? And how does that affect your standing in the scientific community? Blogger Coturnix points to a new proposal for author lists to be like a movie's credits . "Each person is listed, some people more than once, and each person's contribution is very well defined," he writes. (Fri, 02 Oct 2009 23:16:12 GMT)
$7.2 million grant awarded to develop microbicide-releasing vaginal ring
The National Institutes of Health has awarded Albert Einstein College of Medicine of Yeshiva University a four-year, $7.2 million grant to develop a microbicide-releasing vaginal ring to prevent HIV transmission. (Sat, 03 Oct 2009 04:28:03 GMT)
Advanced Liquid Logic awarded an NIAID contract to develop a rapid HIV diagnostic device
Advanced Liquid Logic announced today that it has received a large, four-year contract from the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, for the development of a rapid, point-of-care, diagnostic device for the detection of HIV in low resource settings. (Sat, 03 Oct 2009 04:42:11 GMT)
New Tools in Neuroscience
It's been just three years since the Allen Institute released its mouse brain atlas — a free, publicly available online tool that allows users to zoom in and out of a 3D brain, search by gene, and see expression data — but in that short time, this revolutionary look at the inner workings of a brain has dramatically changed the way neuroscientists do business. (Sat, 03 Oct 2009 08:15:32 GMT)
PNNL scientist Dick Smith awarded Human Proteome Organization's Discovery Award
Laboratory and Battelle Fellow Dick Smith of the Department of Energy's Pacific Northwest National Laboratory has been recognized for his many accomplishments in pioneering the development of proteomics tools. Scientists use these instruments to study the array of proteins and related molecules that make up much of human blood and tissues. (Sat, 03 Oct 2009 08:29:09 GMT)
Genetic Manipulation Mimics Calorie Restriction In Mice, Offering Promise Of Drug Treatments For Age-Related Diseases
Scientists have managed to extend the lifespan of mice by up to a fifth and reduce the number of age-related diseases the animals suffer. The research, which involved blocking a key molecular pathway, mimics the health benefits of reducing calorie intake and suggests that drug treatments for ageing and age-related diseases are feasible. (Sat, 03 Oct 2009 10:10:17 GMT)
Project Annotation
Researchers who study well-documented creatures like fruit flies or E. coli are blessed with the most powerful tools of biology at their fingertips. (Sat, 03 Oct 2009 16:15:32 GMT)
Invitrogen, OGeS, Oxford University, Myriad Genetics, Abbott, Illumina, Genomics Collaborative, Cybridi, Third Wave ...
Invitrogen, aiming to expand into the molecular diagnostics market, "welcomes" existing and impending competition from small, private shops, a company official said yesterday at BIO 2006, held in Chicago this week. (Sun, 04 Oct 2009 00:15:32 GMT)
WKU receives funding for $2.3M super computer
The $2.3 million computer coming to Western Kentucky University has everything but a cape. (Sun, 04 Oct 2009 06:53:22 GMT)
Animals still vital to medical strides
Amid the all-too-often irrational rants about health care in this country, I was having a civil conversation with a friend about the state of health care. He's one of those people who can carry on engaging conversations about a broad range of topics. (Sun, 04 Oct 2009 07:01:04 GMT)
Stimulus-funded research up to $300 million in state
On Monday, a consortium of Seattle scientists will announce $16 million in federal stimulus grants to figure out whether popular cancer treatments and screening tests really save lives. (Sun, 04 Oct 2009 07:17:16 GMT)
When bad bugs get worse
In Greek mythology, the Chimera was a fire-breathing monster with a lion's head, a goat's body and a serpent's tail. The Chimera might be legend, but we have our own version to battle. H1N1 is a combination of reshuffled RNA of different bugs that infected pigs, birds and humans. It's the mutations that created this patchwork virus, known also as swine flu, that fascinate and worry researchers ... (Sun, 04 Oct 2009 08:47:37 GMT)
Embry-whoa! Docs design uber-babies
Fertility clinics are now testing embryo DNA for genetic "mutations" that can trigger dozens of disorders -- from breast cancer to Lou Gehrig's disease -- for prospective parents seeking defect-free babies. "We get accused of playing God," said Dr... (Sun, 04 Oct 2009 11:11:13 GMT)
Scientists watch for possible mutations
By SPENCER HUNT COLUMBUS DISPATCH COLUMBUS - In Greek mythology, the Chimera was a fire-breathing monster with a lion's head, a goat's body, and a serpent's tail. The Chimera might be legend, but we have our own version to battle. H1N1 is a combination of reshuffled RNA of different bugs that infected pigs, birds, and humans. It's the mutations that created this patchwork virus, known also as ... (Sun, 04 Oct 2009 11:22:18 GMT)
Biotech institute that spurned Port St. Lucie is set to dedicate Orlando headquarters Thursday
The glass-clad Burnham Institute for Medical Research shimmers in the sunlight, which pours in through banks of windows and a giant atrium that illuminates the building's interior. (Sun, 04 Oct 2009 16:54:13 GMT)
Humans as Host
The exact number of bacteria living in or on humans isn't known, though it is estimated to be around a trillion. (Sun, 04 Oct 2009 17:15:32 GMT)
Designing drugs and their antidotes together improves patient care
( Duke University Medical Center ) Imagine a surgical patient on a blood-thinning drug who starts bleeding more than expected, and an antidote that works immediately -- because the blood thinner and antidote were designed to work together. Researchers at Duke University Medical Center have engineered a way to do this for an entire, versatile class of drugs called aptamers and published their ... (Sun, 04 Oct 2009 17:27:47 GMT)
Designing Drugs And Their Antidotes Together Improves Patient Care
Imagine a surgical patient on a blood-thinning drug who starts bleeding more than expected, and an antidote that works immediately -- because the blood thinner and antidote were designed to work together. Researchers have engineered a way to do this for an entire, versatile class of drugs called aptamers. (Sun, 04 Oct 2009 19:21:54 GMT)
Designing Drugs, Antidotes Together Improves Patient Care
Imagine a surgical patient on a blood-thinning drug who starts bleeding more than expected, and an antidote that works immediately – because the blood thinner and antidote were designed to work together. (Sun, 04 Oct 2009 21:23:10 GMT)
Filming photons, one million times a second
European researchers have created a CMOS (semiconductor) camera capable of filming individual photons one million times a second. The breakthrough will impact on all the most advanced areas of science and makes Europe the world leader in the technology. (Sun, 04 Oct 2009 22:10:49 GMT)
NIH Grants for PGx, Genotyping, and Genetic Research by State*, as of Dec. 18
Wang has employed genomic microarray techniques to characterize a novel mechanism for regulation of replication elongation by nutrient availability in B. subtilis. (Sun, 04 Oct 2009 23:15:42 GMT)
Clinical Data, ABI, Nanogen, Duke University, Illumina, Qiagen, Genome Diagnostics, FDA, NeoCodex, SureGene, Boston ...
Clinical Data said this week that its Cogenics Division will provide genomic testing services to the pain research community based on a panel of genetic markers developed by Algynomics. (Sun, 04 Oct 2009 23:15:52 GMT)
The Earth Goes Around the Sun, and Stuff
Over at Gene Expression, Razib posts some data from an NSF study on science knowledge among different age groups and different regions around the world. (Sun, 04 Oct 2009 23:16:52 GMT)
QPIF gene project gears up
TO better understand what epigenetic mechanisms impact on the productivity and profitability of tropical beef breeds, a $1.35 million Queensland Primary Industries and Fisheries-led project has attracted national and international collaborative partners. (Mon, 05 Oct 2009 02:06:17 GMT)
Hidden Diversity In Key Environmental Cleanup Microbes Found By Systems Biology Assessment
Researchers analyzed the gene sequences, proteins expressed and physiology of 10 strains of bioremediation microbes called Shewanella. Results showed surprising diversity not seen using traditional microbiology approaches. (Mon, 05 Oct 2009 04:23:06 GMT)
Longer-Lived, Healthier Mice Offer Promise Of Drug Treatments For Age-Related Diseases
Scientists have managed to extend the lifespan of mice by up to a fifth and reduce the number of age-related diseases the animals suffer. The research, which involved blocking a key molecular pathway, mimics the health benefits of reducing calorie intake and suggests that drug treatments for ageing and age-related diseases are feasible. (Mon, 05 Oct 2009 05:36:32 GMT)
Arizona scientists secure $33 mil
In all, Arizona scientists will collect $33.4 million through 101 federal research grants that are funded with stimulus dollars. (Mon, 05 Oct 2009 06:52:11 GMT)
Researchers hope algae can be a source of affordable bio fuel
To many, algae is little more than pond scum, a nuisance to swimmers and a frustration to boaters. But to a growing community of scientists and investors, there is oil locked in all that slimy stuff, and companies are racing to try to figure how best to produce an affordable biofuel. (Mon, 05 Oct 2009 07:19:32 GMT)
Arrayit Deploys Next-Generation Proteomics Platform
Arrayit Corporation is a life sciences and health care technology innovator, and is proud to announce that on October 1st, 2009, the company deployed its next-generation proteomics platform to customers working in the areas of proteomics and in vitro molecular diagnostics. (Mon, 05 Oct 2009 08:11:10 GMT)
Human Proteome Organization Honors PNNL Scientist
Laboratory and Battelle Fellow Dick Smith of the Department of Energy's Pacific Northwest National Laboratory has been recognized for his many accomplishments in pioneering the development of proteomics tools. Scientists use these instruments to study the array of proteins and related molecules that make up much of human blood and tissues. (Mon, 05 Oct 2009 10:08:36 GMT)
Arrayit Deploys Next-Generation Proteomics Platform
SUNNYVALE, CA--(Marketwire - 10/05/09) - Arrayit Corporation (OTC.BB: ARYC - News ), a life sciences and health care technology innovator, announces that on October 1st, 2009, the company deployed its next-generation proteomics platform to customers working in the areas of proteomics and in vitro molecular diagnostics. Arrayit's new proteomics platform provides a patented and comprehensive ... (Mon, 05 Oct 2009 11:00:00 GMT)
Arrayit Deploys Next-Generation Proteomics Platform
Patented Technology Offers Breakthrough for Multivariate Molecular Diagnostics (Mon, 05 Oct 2009 11:33:08 GMT)
IO Informatics’ Working Solution
Bio-IT World | The software company has built a Personalized Medicine working group to tackle workflow bottlenecks. (Mon, 05 Oct 2009 11:33:40 GMT)
UW Hosts NIH Genomics Center
Puget Sound Business Journal | The University of Washington has received $32 million to launch a new genomics research center as part of a nationwide project to study heart, lung, and blood disease. (Mon, 05 Oct 2009 11:34:30 GMT)
Next-Generation Phred Software Squeezes More Data From Illumina Runs
Bio-IT World | Speaking at a conference in Barcelona last week on next-generation sequencing, Philip Green presented benchmark results on a new software package that extracts significantly more reads and data per run compared to the current Illumina tools. (Mon, 05 Oct 2009 11:34:40 GMT)
Prof P V Bhartam of NIPER bags Ranbaxy Research Award
Professor P V Bhartam, Department of Medicinal Chemistry, of National Institute of Pharmaceutical Education and Research (NIPER), SAS Nagar, Chandigarh has bagged Ranbaxy Research Award for the year 2008. The country's prestigious award will be given to him in the field of 'Pharmaceutical Sciences' which will be jointly shared by Dr G V Madhava Sharma, scientist F (deputy director), head-Organic ... (Mon, 05 Oct 2009 11:36:25 GMT)
New proteomics platform to customers working in proteomics and in vitro molecular diagnostics areas
Arrayit Corporation, a life sciences and health care technology innovator, announces that on October 1st, 2009, the company deployed its next-generation proteomics platform to customers working in the areas of proteomics and in vitro molecular diagnostics. (Mon, 05 Oct 2009 11:57:45 GMT)
Arrayit deploys new proteomics platform
Arrayit Corporation, a life sciences and health care technology innovator, announces that on October 1st, 2009, the company deployed its next-generation proteomics platform to customers working in the areas of proteomics and in vitro molecular diagnostics. (Mon, 05 Oct 2009 13:13:49 GMT)
University of Washington receives $25 million to create Northwest Genomics Center
( University of Washington - Health Sciences/UW News, Community Relations & Marketing ) The National Heart, Lung, and Blood Institute announced Oct. 1 that the University of Washington will receive two of the six "Grand Opportunity" NHLBI Large-Scale DNA Sequencing Project awards. The UW will receive $25 million to launch the Northwest Genomics Center, one of two sequencing centers for the ... (Mon, 05 Oct 2009 13:21:27 GMT)
2 of today's new Nobel Prize winners were speakers at UCI
Carol Greider and Jack W. Szostak spoke about chromosomes, cells. (Mon, 05 Oct 2009 14:41:55 GMT)
Research and Markets: Weedy and Invasive Plant Genomics Assesses the Areas of Future Research Necessary to Defeat ...
DUBLIN----Research and Markets has announced the addition of John Wiley and Sons Ltd's new report "Weedy and Invasive Plant Genomics" to their offering. (Mon, 05 Oct 2009 14:42:00 GMT)
Filming photons, one million times a second
(PhysOrg.com) -- European researchers have created a CMOS (semiconductor) camera capable of filming individual photons one million times a second. The breakthrough will impact on all the most advanced areas of science and makes Europe the world leader in the technology. (Mon, 05 Oct 2009 14:46:19 GMT)
In Print
Journal: American Journal of Clinical Pathology . 2009 Sep;132(3):349-60. Title: Validation of the Agilent 244K oligonucleotide array-based comparative genomic hybridization platform for clinical cytogenetic diagnosis. (Mon, 05 Oct 2009 16:00:32 GMT)
Inventive combination of research approaches identifies new target for treating leukemia
( Cell Press ) New research integrates sophisticated interdisciplinary approaches to solve a molecular mystery that may lead to alternative therapeutic strategies for acute myeloid leukemia (AML). The study, published by Cell Press in the October issue of the journal Cancer Cell, identifies a previously unrecognized AML target that responds well to pharmacological inhibition and may be an ... (Mon, 05 Oct 2009 16:21:11 GMT)
$7.5 million grant to fund TGen-UA Pharmacy medicinal chemistry program
( The Translational Genomics Research Institute ) The National Institutes of Health today awarded a $7.5 million grant to the Translational Genomics Research Institute and The University of Arizona to fund a drug discovery and development center that puts renewed focus on the role of medicinal chemistry. (Mon, 05 Oct 2009 16:21:41 GMT)
NEPAF attracts Protein Forest
The North East Proteome Analysis Facility has attracted interest from Protein Forest, a Boston, USA-based research firm specialising in Proteomics. (Mon, 05 Oct 2009 16:35:03 GMT)
Arizona scientists secure $33M
In all, Arizona scientists will collect $33.4 million through 101 federal research grants that are funded with stimulus dollars. (Mon, 05 Oct 2009 16:55:27 GMT)
SAGE launches Genes & Cancer
( SAGE Publications ) SAGE announces Genes & Cancer, a monthly journal edited by Dr. Prem Reddy, founder and previous editor-in-chief of the prestigious and highly-ranked Oncogene. (Mon, 05 Oct 2009 17:35:36 GMT)
Correlagen to Launch Genetic Cardiovascular Disease Assay on Helicos Platform This Month
Genetic testing company Correlagen Diagnostics plans to launch a comprehensive assay for genetic cardiovascular disease this month that will run on a Helicos BioSciences' sequencing platform in its CLIA lab, In Sequence has learned. (Mon, 05 Oct 2009 17:45:32 GMT)
$16 Million in Federal Stimulus Funding Establishes Seattle as a Hub of Comparative-Effectiveness Research In Cancer
SEATTLE, Oct. (Mon, 05 Oct 2009 18:10:24 GMT)
Federal Stimulus Funding Channels More Than $40 Million to Fred Hutchinson Cancer Research Center
SEATTLE, Oct. 5 /PRNewswire/ -- Scientists at Fred Hutchinson Cancer Research Center have been awarded 60 research grants totaling nearly $40.4 million under the American Recovery & Reinvestment Act of 2009. The totals reflect data available as of Oct. (Mon, 05 Oct 2009 18:10:34 GMT)
VBI awarded $27 million from NIH to support infectious disease research
( Virginia Tech ) The NIAID funding will be used to integrate vital information on pathogens, provide key resources and tools to scientists, and help researchers analyze genomic, proteomic and other data arising from infectious disease research. The overall program will comprise four new Bioinformatics Resource Centers and a new gateway portal for the entire project. Each BRC will focus on one ... (Mon, 05 Oct 2009 19:06:30 GMT)
IBM, Google, and colleges talk cloud projects
Sponsored by IBM, Google, and the National Science Foundation (NSF), university researchers are gathering Monday to tout their respective cloud computing projects as part of the CLuE (Cluster Exploratory) program. (Mon, 05 Oct 2009 19:18:17 GMT)
Center for Healthcare Quality receives $4.8 million grant
Published: Monday, October 5, 2009 at 2:27 p.m. Last Modified: Monday, October 5, 2009 at 2:27 p.m. (Mon, 05 Oct 2009 19:35:53 GMT)
Proxeon Taps Europe, Asia Distributors
NEW YORK (GenomeWeb News) - Proteomics tools company Proxeon said today that it has expanded its reach in Europe and Asia through six new distribution agreements. (Mon, 05 Oct 2009 20:01:03 GMT)
Inventive Combination Of Research Approaches Identifies New Target For Treating Leukemia
New research integrates sophisticated interdisciplinary approaches to solve a molecular mystery that may lead to alternative therapeutic strategies for acute myeloid leukemia (AML). (Mon, 05 Oct 2009 20:39:24 GMT)
Genome Prairie Funds Flax Sequencing
NEW YORK (GenomeWeb News) - Two University of Manitoba research efforts have received a total of around C$1.7 million ($1.6 million) from Genome Prairie to pursue genomics research, including a genome sequencing project, into flax and how it may be used for biofuel. (Mon, 05 Oct 2009 21:45:52 GMT)
Phoenix lab gets cancer study grant
PHOENIX, Oct. 5 (UPI) -- A share of federal research grants for study of the genetic roots of cancer will more than triple the workforce of a Phoenix laboratory, its chief said. (Mon, 05 Oct 2009 21:56:33 GMT)
SiBEAM's Second Generation Chipsets Accelerate WirelessHD Market Adoption
TOKYO & SUNNYVALE, Calif.----SiBEAM, the leading innovator of 60GHz wireless solutions and developer of high-speed wireless communication platforms, today unveiled its second generation 60GHz chipsets based on the WirelessHD® specification at CEATEC Japan. (Mon, 05 Oct 2009 23:00:00 GMT)
Hyseq Expands Genomics Program, Names Director
SUNNYVALE, Calif.-- Hyseq announced the appointment of Dennis Ballinger as senior director of functional genomics/cardiovascular. The company said it plans to strengthen its development program in the genetic causes of cardiovascular diseases. (Mon, 05 Oct 2009 23:05:19 GMT)
Grant will aid getting promising drugs to market
The Translational Genomics Research Institute and University of Arizona will split a $7.5 million recovery-act grant to get promising drugs to market more quickly. (Mon, 05 Oct 2009 23:25:27 GMT)
UBC researchers identify key behavior of immune response to Listeria
A team of University of British Columbia microbiologists has identified a key defense mechanism used by the immune system against Listeria with strong implications for the future development of vaccines. (Tue, 06 Oct 2009 00:21:10 GMT)
Phoenix lab gets cancer study grant
A share of federal research grants for study of the genetic roots of cancer will more than triple the workforce of a Phoenix laboratory, its chief said. The International Genomics Consortium, at the downtown Phoenix Biomedical Campus, will receive some of the $275 million in federal research grants aimed toward finding the genetic roots of cancer. (Tue, 06 Oct 2009 02:54:00 GMT)
Beckman Prepares for Genomics Services Gold Rush
Bio-IT World | Like many others, Beckman Coulter is betting the mainstreaming of genomics-based research and the future growth of personalized medicine will create a large, robust market for genomics services: Beckman Coulter Genomics (BCG). As research and medical communities rush to dig gold from mounting genomics data, BCG hope to sell the needed picks and shovels. (Tue, 06 Oct 2009 04:03:40 GMT)
New journal on cancer biology and genetics
SAGE announces Genes & Cancer, a monthly journal edited by Dr. Prem Reddy, founder and previous Editor-in-Chief of the prestigious and highly-ranked Oncogene. (Tue, 06 Oct 2009 05:13:46 GMT)
NIH awards $27,670,448 to VBI to support biomedical research on infectious diseases
The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), has awarded a five-year, $27,670,448 contract to the CyberInfrastructure Group (CIG) of the Virginia Bioinformatics Institute (VBI) at Virginia Tech to support the biomedical research community's work on infectious diseases. (Tue, 06 Oct 2009 05:58:19 GMT)
BIOBASE And CLC bio Partner to Give Genomics Researchers World Class Solution
HANNOVER, Germany----Today at the Biotechnica / Bio-IT World Europe conference in Hannover, Germany, BIOBASE and CLC bio announced a partnership to integrate BIOBASE's comprehensive TRANSFAC® database with CLC bio's popular workbenches and award-winning server solution. (Tue, 06 Oct 2009 06:59:00 GMT)
Fred Hutchinson Cancer Research Center receives 60 research grants totaling nearly $40.4 million
Scientists at Fred Hutchinson Cancer Research Center have been awarded 60 research grants totaling nearly $40.4 million under the American Recovery & Reinvestment Act of 2009. The totals reflect data available as of Oct. 1 and reported by the National Institutes of Health. (Tue, 06 Oct 2009 07:13:17 GMT)
USC wins grant for research trials
Published: Tuesday, October 6, 2009 at 3:15 a.m. Last Modified: Monday, October 5, 2009 at 10:03 p.m. (Tue, 06 Oct 2009 07:21:32 GMT)
NIAID's grant to VBI for biomedical research on infectious diseases
The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), has awarded a five-year, $27,670,448 contract to the CyberInfrastructure Group (CIG) of the Virginia Bioinformatics Institute (VBI) at Virginia Tech to support the biomedical research community's work on infectious diseases. (Tue, 06 Oct 2009 08:12:42 GMT)
Illumina launches IlluminaCompute for its Genome Analyzer sequencing platform
At the BioIT World Europe Conference, Illumina, Inc. announced the launch of IlluminaCompute, a fully integrated computing solution for its Genome Analyzer sequencing platform. (Tue, 06 Oct 2009 08:57:26 GMT)
BIOBASE to integrate its TRANSFAC database with CLC bio's popular workbenches
Today at the Biotechnica / Bio-IT World Europe conference in Hannover, Germany, BIOBASE and CLC bio announced a partnership to integrate BIOBASE's comprehensive TRANSFAC® database with CLC bio's popular workbenches and award-winning server solution. (Tue, 06 Oct 2009 09:42:12 GMT)
National Science Foundation funds Va. Tech study of crop drought responses
BLACKSBURG — An international team of researchers, led by Virginia Bioinformatics Institute Professor Andy Pereira, has been awarded a three-year, $2.4 million grant from the National Science Foundation to develop a systems biology approach to help combat the effects of drought on a variety of staple food crops. (Tue, 06 Oct 2009 09:54:48 GMT)
The Queensland Facility for Advanced Bioinformatics Selects IPA in Multi-Year Deal for Systems Biology Effort
Ingenuity Systems, the leading provider of information solutions for life science researchers, and Millennium Science, Ingenuity Systems' exclusive distributor for Australia and New Zealand, today announced a multi-year deal for Ingenuity Pathway Analysis with the Queensland Facility for Advanced Bioinformatics . (Tue, 06 Oct 2009 10:00:00 GMT)
Xenomics Appoints Bruce A. Huebner as Chief Executive Officer and Board Member
NEW YORK----Xenomics, Inc. a developer of trans-renal molecular diagnostic technologies, announced today the appointment of Bruce A. Huebner, a veteran of the diagnostics industry, as Chief Executive Officer and board director. (Tue, 06 Oct 2009 11:30:00 GMT)
NIMH awards SRI International a $6.3M contract for study of ligands for brain imaging research
SRI International, an independent nonprofit research and development organization, announced today that it has been awarded a $6.3 million contract by the National Institute of Mental Health (NIMH) to conduct preclinical safety studies of promising novel ligands that will be used for brain imaging research and clinical applications. (Tue, 06 Oct 2009 11:42:39 GMT)
Federal stimulus funding channels more than $40 million to Fred Hutchinson Cancer Research Center
( Fred Hutchinson Cancer Research Center ) Scientists at Fred Hutchinson Cancer Research Center have been awarded 60 research grants totaling nearly $40.4 million under the American Recovery & Reinvestment Act of 2009. The totals reflect data available as of Oct. 1 and reported by the National Institutes of Health. The individual projects range in amount from $4.8 million to $33,596 and benefit ... (Tue, 06 Oct 2009 13:01:34 GMT)
New drug aims to 'seek and destroy' many types of cancer
( The Translational Genomics Research Institute ) A new drug designed to "seek and destroy" common cancers such as breast, prostate, endometrial, pancreatic, ovarian, skin and testicular cancers is being tested at TGen Clinical Research Services at Scottsdale Healthcare. (Tue, 06 Oct 2009 13:13:12 GMT)
News in genomics [Genetic Future]
Things are as usual moving at ludicrous speed in the world of genomics, but sadly I only have time to post a few pointers to some of the most striking developments. IBM is moving into the third-generation sequencing arena . The company is developing a new sequencing technology based on tiny nanopores - a field already being explored by the understated British nobility of sequencing, Oxford ... (Tue, 06 Oct 2009 14:20:30 GMT)
New Target For Treating Leukemia Identified By Inventive Combination Of Research Approaches
New research integrates sophisticated interdisciplinary approaches to solve a molecular mystery that may lead to alternative therapeutic strategies for acute myeloid leukemia (AML). (Tue, 06 Oct 2009 15:26:11 GMT)
UNC Group Honors Ms. Ryan Phelan for Her Leadership in Developing Patient-Directed Programs in Pharmacogenomics and ...
CHAPEL HILL, NC--(Marketwire - 10/06/09) - Ryan Phelan is this year's recipient of the Award for Patient Service from the Institute for Pharmacogenomics and Individualized Therapy at the University of North Carolina at Chapel Hill. Ryan Phelan is CEO and founder of DNA Direct, a company that delivers guidance and decision support for genomic medicine to patients, providers and payors. DNA Direct ... (Tue, 06 Oct 2009 16:24:00 GMT)
UNC Group Honors Ms. Ryan Phelan for Her Leadership in Developing Patient-Directed Programs in Pharmacogenomics and ...
DNA Direct CEO and Founder to Receive UNC Patient-Care Award (Tue, 06 Oct 2009 17:35:33 GMT)
NIH awards $4.8M grant to USC’s Center for Healthcare Quality
The funding will accelerate the development of a statewide Internet-based research network that will enable patients to identify and volunteer for clinical research trials in the state, receive notifications of future research trials related to their condition and protect their personal health information. (Tue, 06 Oct 2009 17:55:12 GMT)
Paired Ends
Samuel Levy has joined the genomic medicine program of Scripps Health as director of genomic sciences. He joins Scripps from the J. Craig Venter Institute in Rockville, Md., where he was director and professor of human genomics. (Tue, 06 Oct 2009 18:15:32 GMT)
NIAID Awards $67.5M for Bioinformatics Resource Centers, But Cuts Number of Centers in Half
The National Institute of Allergy and Infectious Diseases has awarded $67.5 million over five years to four Bioinformatics Resource Centers for Infectious Diseases, which collect, annotate, and host genomic, proteomic, and metabolic information and datasets, and offer analysis and visualization tools to study pathogens. (Tue, 06 Oct 2009 20:30:37 GMT)
NIST to Make External RNA Control Consortium Spike-ins Available for Array Users in 2010
The US National Institute of Standards and Technology plans to make standard reference RNA controls available to microarray users by early next year, BioArray News has learned. (Tue, 06 Oct 2009 21:00:37 GMT)
Phase 2 of 2D Gel Reproducibility Effort Yields 'Significant' Confidence Levels
In the second phase of a campaign to test the reproducibility of 2D gel technology, 10 out of 17 laboratories, or 60 percent, were able to generate gel images that fell within a 95-percent confidence level in an inter-laboratory study. (Tue, 06 Oct 2009 21:00:49 GMT)
MALDI-Based Method May Reduce Cost of Rx-Screening Assays, Speed Drug Development
Researchers from the University of Cincinnati and MDS Analytical Technologies have used mass spectrometry to develop a high-throughput screening method for drug discovery they say can be more precise and cost-effective than existing techniques. (Tue, 06 Oct 2009 21:00:56 GMT)
IP Roundup
Nanogen of San Diego has received US Patent No. 7,597,932, "Mesoporous permeation layers for use on active electronic matrix devices." The patent describes synthetic polymer hydrogel permeation layers for use on active electronic matrix devices for biological assays. (Tue, 06 Oct 2009 21:30:43 GMT)
New Product Watch
Arrayit last week launched a proteomics microarray platform for customers working in the areas of proteomics and in vitro molecular diagnostics. Arrayit said the platform provides instrumentation, software, and consumables solution for peptide microarray analysis. (Tue, 06 Oct 2009 21:30:53 GMT)
Emory Wins $3.5M NIH Stimulus Grant to Build CNV Atlas of Human Development
The National Institutes of Health will spend nearly $3.5 million over the next two years to finance the creation of an online database of copy number variation information related to abnormal phenotypes. (Tue, 06 Oct 2009 21:45:43 GMT)
New Network to Tackle Major Issues in Microarray Data Analysis at September Retreat
To tackle the mountain of issues involved in microarray data analysis, David Allison, a biostatistician from the University of Alabama at Birmingham, is bringing together a diverse group of researchers for a retreat at Mohonk Mountain House in New Paltz, NY, from September 10 through 13. (Tue, 06 Oct 2009 23:05:59 GMT)
Australian Bioinformatics Facility to Use Ingenuity Platform
Ingenuity Systems this week announced a multi-year deal for its Ingenuity Pathway Analysis platform with the Queensland Facility for Advanced Bioinformatics in Australia. (Tue, 06 Oct 2009 23:15:32 GMT)
Filming Photons, One Million Times A Second
Researchers have created a CMOS (semiconductor) camera capable of filming individual photons one million times a second. (Wed, 07 Oct 2009 01:22:14 GMT)
BYU researchers seek to answer mysteries of Down syndrome
Scientists remain perplexed on how to prevent Down syndrome, but the research BYU students and professors are conducting could provide the answer to this timeless mystery. These researchers look at chromosome 21 in mice with Down syndrome to try and figure out why having three copies of the genes in chromosome 21, rather than two, causes the changes in jaw structure found in Down syndrome ... (Wed, 07 Oct 2009 03:46:13 GMT)
Clinical Genomics Continues Collaborative Research With CSIRO
Sydney-based Clinical Genomics Pty Ltd and CSIRO have entered into a new phase in their collaboration to develop improved diagnostics for cancers of the colon and rectum . (Wed, 07 Oct 2009 06:17:00 GMT)
Clinical Genomics Continues Collaborative Research With CSIRO
SYDNEY, October 7 /PRNewswire/ -- Sydney-based Clinical Genomics Pty Ltd and CSIRO have entered into a new phase in their collaboration to develop improved diagnostics for cancers of the colon and rectum (bowel cancer). (Wed, 07 Oct 2009 06:43:35 GMT)
TGen and Scottsdale Healthcare discover new 'pathways'
( The Translational Genomics Research Institute ) Using computer modeling, the Translational Genomics Research Institute and Scottsdale Healthcare have discovered lung cancer "pathways" that could become targets for new drugs, according to a scientific paper published online today by the Journal of Thoracic Oncology. (Wed, 07 Oct 2009 07:21:10 GMT)
Using computer modeling, Tgen and Scottsdale Healthcare discover new 'pathways' for lung cancer
Using computer modeling, the Translational Genomics Research Institute and Scottsdale Healthcare have discovered lung cancer 'pathways' that could become targets for new drugs, according to a scientific paper published online today by the Journal of Thoracic Oncology. (Wed, 07 Oct 2009 09:57:32 GMT)
NCKU Senior Executive Vice President, Dr. Da-Hsuan Feng, Received "Chime Bell Award 2009"
TAINAN, Taiwan----Senior Executive Vice President of National Cheng Kung University , Dr. Da-Hsuan Feng, has recently been honored with “Chime Bell Award 2009” from The People’s Government of Hubei Province in China with the recognition of his personnel outstanding contributions to the economic construction and social development. (Wed, 07 Oct 2009 10:23:00 GMT)
Clinical Genomics Continues Collaborative Research With CSIRO
SYDNEY, Oct. (Wed, 07 Oct 2009 11:07:50 GMT)
Life science careers touted
A program designed to bring careers in the life sciences within reach of more Western New York job-seekers was rolled out Tuesday by a consortium of agencies and businesses led by two branches of the University at Buffalo. (Wed, 07 Oct 2009 11:08:58 GMT)
Arrayit Corporation CEO Reports to Shareholders
SUNNYVALE, CA--(Marketwire - October 7, 2009) - Arrayit Corporation ( OTCBB : ARYC ) Letter to Shareholders from the CEO October 7, 2009 With the start of trading of Arrayit Corporation (ARYC) on the bulletin board in March, 2009, we initiated a deliberate and measured strategy to introduce Arrayit's scientific accomplishments of the past 13 years to our shareholders. As we have laid the ... (Wed, 07 Oct 2009 11:47:45 GMT)
Geospiza Awarded SBIR Grant for Software Systems for Detecting Rare Mutations
SEATTLE----Geospiza, Inc., the market leading developer of genetic analysis software, today announced the receipt of a Phase I SBIR grant for “Software Systems for Detecting Rare Mutations” from the National Human Genome Research Institute . (Wed, 07 Oct 2009 11:55:00 GMT)
Monsanto Delivers Earnings Per Share Increase; Outlines Seeds and Genomics Growth in 2010
- (Wed, 07 Oct 2009 12:00:00 GMT)
Arrayit Corporation CEO updates shareholders
With the start of trading of Arrayit Corporation (ARYC) on the bulletin board in March, 2009, we initiated a deliberate and measured strategy to introduce Arrayit's scientific accomplishments of the past 13 years to our shareholders. As we have laid the foundation for the announcement of future initiatives through this awareness campaign, we have seen interest in our stock steadily increase. (Wed, 07 Oct 2009 12:27:17 GMT)
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