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Alpha Innotech Announces the Election of Two New Board Members
SAN LEANDRO, Calif.----Alpha Innotech Corp. , a leading provider of gel imaging systems for drug discovery and life science research, announced that Mssrs. Chris van Ingen and Dr. Shahram Hejazi were elected to its Board of Directors during the Company's most recent annual meeting. (Wed, 01 Jul 2009 01:14:00 GMT)
New Test Can Detect Both Genetic And Chromosomal Abnormalities In Embryos
One-step screening for both genetic and chromosomal abnormalities has come a stage closer as scientists announced that an embryo test they have been developing has successfully screened cells taken from spare embryos that were known to have cystic fibrosis. The technique, known as genomewide karyomapping, was capable of not only detecting diseases caused by a specific gene mutation, in this case ... (Wed, 01 Jul 2009 02:22:00 GMT)
Making the Decision Might Be the Toughest Part
At Brian Switek's Laelaps blog, he writes a heartfelt post, chronicling what he calls his "tortuous academic path to date." For some vicarious living, and maybe to feel better about the fact that you've actually made it into graduate school without that much existential angst, check out his post here . (Wed, 01 Jul 2009 05:18:03 GMT)
MS vs PhD
Should you have stopped at your Master’s degree? Derek Lowe on his blog discusses whether it's worth getting a PhD. As he sums it up, it's easier to get hired as a non-PhD, but more difficult to advance very far. While PhDs can advance, they have a tougher time landing that hard-to-come-by job. (Wed, 01 Jul 2009 05:18:13 GMT)
Chalk One Up for Scientific Destiny
As part of the Scientiae blog carnival , ScienceWoman writes about how her career goals changed from when she began her PhD -- "I'll either focus on teaching or on research, but I don't want a job where I have to be good at both" -- to now, as an assistant professor. (Wed, 01 Jul 2009 05:18:23 GMT)
Or 280 Billion Haagen-Dazs Bars
If you had the choice between buying 32,407 Alvin submarines or bailing out the US economy, what would you do? (We know, it's a tough call.) Jonathan Eisen tries to get his head around the $700 billion bailout effort here in the US by blogging about what else that money could buy . His list includes: 280,000 liters of Taq polymerase, 538 million open access fees for publishing in PLoS One, and ... (Wed, 01 Jul 2009 05:18:33 GMT)
At ISMB, U Manchester Releases Biocatalogue, a Web Services Registry and Social Networking Hub
STOCKHOLM, Sweden – The University of Manchester today launched Biocatalogue , a registry of curated life science web services intended to help scientists easily connect with teams offering web-based bioinformatics resources. (Wed, 01 Jul 2009 06:47:53 GMT)
Exiqon Announces 2009 North American Grant Award Winners
Exiqon A/S (NASDAQ OMX Copenhagen: "EXQ") today announced the two winners of their 2009 North American Grant Program. Exiqon had recently announced the development of a new research grant program, open to researchers from academic and non-profit institutions across North America, engaged in microRNA research. (Wed, 01 Jul 2009 07:01:00 GMT)
Exiqon Announces 2009 North American Grant Award Winners
Exiqon A/S (NASDAQ OMX Copenhagen: "EXQ") today announced the two winners of their 2009 North American Grant Program. Exiqon had recently announced the development of a new research grant program, open to researchers from academic and non-profit institutions across North America, engaged in microRNA research. (PRWeb Jul 1, 2009) Read the full story at ... (Wed, 01 Jul 2009 07:09:18 GMT)
Rubicon Genomics Introduces PicoPlex Single Cell Whole Genome Amplification Kit For Pre-Implantation Genetic ...
Rubicon Genomics, Inc., a developer of pre-amplification products that enable optimal performance of the most advanced genetic analysis tools, announced today the release of its PicoPlex Single Cell Whole Genome Amplification (WGA) kit-a more rapid, accurate and reproducible method for amplifying single genomes than current technologies. (Wed, 01 Jul 2009 09:31:10 GMT)
Genetic analysis reveals secrets of scorpion venom
Transcriptomic tests have uncovered the protein composition of venom from the Scorpiops jendeki scorpion. Researchers writing in the open access journal BMC Genomics have carried out the first ever venom analysis in this arachnid, and discovered nine novel poison molecules, never before seen in any scorpion species. (Wed, 01 Jul 2009 10:03:36 GMT)
Hunt For Blood Test To Determine Melanoma Survival Rates
Research at the University of Leicester will be breaking new ground in the search for a simple blood test that could tell whether a patient with melanoma has the condition in an aggressive form. Melanoma is the most aggressive form of skin cancer. (Wed, 01 Jul 2009 10:22:52 GMT)
Secrets Of Scorpion Venom Revealed
Transcriptomic tests have uncovered the protein composition of venom from the Scorpiops jendeki scorpion. (Wed, 01 Jul 2009 12:25:28 GMT)
Researchers Show New Antioxidant Could Help Treat Cardiovascular Disease
Researchers at the University of Glasgow believe they have found a potential new treatment for cardiovascular disease which reduces blood pressure. Scientists at the British Heart Foundation Glasgow Cardiovascular Research Centre (BHF GCRC) used a recently-developed antioxidant called MitoQ10 to prevent damage to the mitochondria of cells in an experimental model of hypertension and stroke. (Wed, 01 Jul 2009 12:25:28 GMT)
Cranes Software's FY09 Consolidated Revenues up 33% to Rs. 5,289 Million and PAT Higher by 6% to Rs. 1,213.1 Million
BANGALORE, India----Cranes Software International Ltd. , a Company that provides Enterprise Statistical Analytics and Engineering Simulation Software Products and Solutions across the globe, today announced its audited financial results for the quarter and year ended March 31, 2009. (Wed, 01 Jul 2009 13:17:00 GMT)
New e-science service could accelerate cancer research
( University of Manchester ) The University of Manchester and the European Molecular Biology Laboratory's European Bioinformatics Institute have launched a major new e-science resource for biologists -- which could accelerate research into treatments for H1N1 flu and cancer. (Wed, 01 Jul 2009 13:46:24 GMT)
Hall, Rosbash and Young share $500,000 Gruber neuroscience prize
( Robin Leedy & Associates, Inc. ) The 2009 neuroscience prize of the Peter and Patricia Gruber Foundation is being awarded to Jeffrey Hall, professor of neurogenetics at the University of Maine; Michael Rosbash, professor and director of the National Center for Behavioral Genomics at Brandeis University; and Michael Young, professor and head of the Laboratory of Genetics at Rockefeller ... (Wed, 01 Jul 2009 14:13:28 GMT)
Genetic And Chromosomal Abnormalities In Embryos Detected By New Test
One-step screening for both genetic and chromosomal abnormalities has come a stage closer as scientists announced that an embryo test they have been developing has successfully screened cells taken from spare embryos that were known to have cystic fibrosis. (Wed, 01 Jul 2009 15:09:32 GMT)
Secrets Of Scorpion Venom Revealed By Genetic Analysis
Transcriptomic tests have uncovered the protein composition of venom from the Scorpiops jendeki scorpion. Researchers writing in the open access journal BMC Genomics have carried out the first ever venom analysis in this arachnid, and discovered nine novel poison molecules, never before seen in any scorpion species. (Wed, 01 Jul 2009 15:10:53 GMT)
Pehaps There Are Better Ways to Spend the Money
It's not just financial firms that are being looked at askance over the pay of executives and board members -- biotech companies are also feeling the heat, reports the Wall Street Journal . An article in the June issue of Nature Biotechnology analyzed the salaries of 51 UK biotech companies , finding the average compensation for a chief executive to be £297,947 (US$493,616), and noting that ... (Wed, 01 Jul 2009 15:48:13 GMT)
Like a Love Triangle
Roche is leaving PhRMA for BIO . Genentech, which Roche recently acquired, was a member of BIO and during the reorganization of the companies, Roche assets in the US became Genentech. (Wed, 01 Jul 2009 15:48:24 GMT)
Cancer Run-Down
The cancer labs of Elizabeth Blackburn, Chad Mirkin, and Elaine Mardis and Rick Wilson get shout-outs in three US News & World Report articles. Blackburn is looking to exploit cancer cells' use of telomerase to engineer a way to kill the cells; she is also intrigued by lifestyle influences, such as exercise and nutrition, on telomerase levels. (Wed, 01 Jul 2009 15:48:34 GMT)
Signature Genomic Laboratories Announces Appointment of New Laboratory Directors
SPOKANE, Wash.----Signature Genomic Laboratories has appointed two new laboratory directors, Drs. Marilyn Slovak, Ph.D., and J. Britt Ravnan, Ph.D. Signature, which performs diagnostic genetic testing of chromosome abnormalities in individuals with unexplained mental retardation and/or birth defects, anticipates the appointments will help the company manage its steadily increasing volume of cases. (Wed, 01 Jul 2009 16:08:00 GMT)
Sequencing the Teddy Bear
Sean Eddy's blog pointed us to Kevin Larry's "mildly enthused" interview with Cofactor Genomics, in which the co-founders detail "one of the more challenging projects they've worked on" — the teddy bear genome. (Wed, 01 Jul 2009 16:17:53 GMT)
Fate Therapeutics Licenses Stem-Cell Modulators for Bone Regeneration from UCLA
Stem cell therapeutics company Fate Therapeutics said today that it has acquired from the University of California, Los Angeles, exclusive intellectual property rights covering small molecule compositions and methods for inducing bone formation. (Wed, 01 Jul 2009 16:32:53 GMT)
Axel Ullrich named winner of 2009 Dr. Paul Janssen Award for Biomedical Research
( Porter Novelli ) Johnson & Johnson announced that Axel Ullrich, Ph.D., director of the Department of Molecular Biology at the Max Planck Institute of Biochemistry in Germany, whose discoveries have led to novel cancer therapies including Herceptin (trastuzumab), is the winner of the 2009 Dr. Paul Janssen Award for Biomedical Research. An independent committee of world-renowned scientists ... (Wed, 01 Jul 2009 17:14:28 GMT)
Canadian Initiative Developing Platform to Map Human Interactome, Eyes International Consortium
A multi-million dollar effort to create a technology platform to map the human interactome is underway in Canada with an eye to making it international. (Wed, 01 Jul 2009 17:47:53 GMT)
Barnes-Jewish Hospital launches $50M campaign for cancer research
The Barnes-Jewish Hospital Foundation has launched a 10-year, $50 million fundraising effort to accelerate breakthroughs in cancer prevention, diagnosis, treatment and cures. (Wed, 01 Jul 2009 18:44:36 GMT)
BlueGnome to Distribute PicoPlex Technology from Rubicon Genomics
ANN ARBOR, Mich.----Rubicon Genomics, Inc., a developer of pre-analytical amplification products that enable optimal performance of advanced genetic analysis tools, announced today that it has reached agreement with BlueGnome to non-exclusively market its PicoPlex™ technology to In Vitro Fertilization researchers under the name SurePlex DNA Amplification System as part of the BlueGnome 24sure ... (Wed, 01 Jul 2009 19:31:00 GMT)
GWC Lands $110K NSF Stimulus Grant to Develop Protein Biochip
NEW YORK (GenomeWeb News) – The proteomics products company GWC Technologies said today that it has received a Small Business Innovation Research grant from the National Science Foundation to continue developing its Carbon-on-Metal protein array analysis technology. (Wed, 01 Jul 2009 19:48:13 GMT)
Illumina Announces Preliminary Revenue for Second Quarter 2009
SAN DIEGO----Illumina, Inc. today announced, based on management's preliminary financial review, second quarter revenue of approximately $161 million compared to guidance of $168 to $173 million. (Wed, 01 Jul 2009 20:01:00 GMT)
Microbial analysis, micropatterning methods featured in Cold Spring Harbor Protocols
( Cold Spring Harbor Laboratory ) The July issue of Cold Spring Harbor Protocols presents a method for quantifying populations of microorganisms in a variety of naturally occurring conditions such as plankton samples or biofilms, as well as a simple, fast and efficient method for generating micropatterns for cellular studies. Both methods are freely accessible on the Web site for Cold Spring ... (Wed, 01 Jul 2009 20:23:32 GMT)
U of L helps find breakthrough on kidney ailment
A team including University of Louisville researchers has found the key to a debilitating disease in which the immune system attacks the kidneys — a discovery that could lead to earlier diagnosis and new medicines for a chronic condition afflicting 100,000 Americans. (Wed, 01 Jul 2009 21:44:06 GMT)
Common Gene Variations Linked to Schizophrenia, Scientists Say
July 1 (Bloomberg) -- Common variations in genes may underlie schizophrenia, the mental illness known to run in families for more than 100 years, with no one single variation conferring the majority of risk, three studies show. (Wed, 01 Jul 2009 22:02:25 GMT)
DNASTAR, Inc. launches latest version of next generation sequencing software
DNASTAR, Inc. introduced today its latest version of Next-Gen sequence assembly software for desktop computers. NGen2.0 is the company’s third upgrade of NGS software in the past 18 months, reflecting the rapidly changing needs of the market. (Wed, 01 Jul 2009 23:03:34 GMT)
UB to host major biomedical ontology conference
Whether and how medical personnel and their digital systems can talk to one another in a meaningful way is a subject pertinent to the health of patients about whom they “converse.” (Wed, 01 Jul 2009 23:25:19 GMT)
PM promises private school style education for all
Gordon Brown guarantees an education individually tailored for each child, but parents could be fined if they refuse to take more responsibility for their children's behaviour Parents should be able to expect a private school style education under plans to reform the education system, the prime minister said today. Families will be guaranteed personal tutors, one-to-one tuition, and a range of ... (Thu, 02 Jul 2009 02:17:38 GMT)
Scientists Find Differences in Embryonic Stem Cells and Reprogrammed Skin Cells
UCLA researchers have found that embryonic stem cells and skin cells reprogrammed into embryonic-like cells have inherent molecular differences, demonstrating for the first time that the two cell types are clearly distinguishable from one another. (Thu, 02 Jul 2009 04:31:25 GMT)
That's One Long To-Do List
President-elect Obama was the first major political candidate to leverage the Internet for networking and communication, and it doesn’t look like he’s stopping that train. (Thu, 02 Jul 2009 05:17:53 GMT)
Genes Are So Passé
What is a " gene ?" asks Bora Zivkovic. It used to be a unit of heredity, but is it now a stretch of DNA? Or something else? A new, philosophical article in PLoS One by Evelyn Fox Keller and David Harel delves into the definition of a gene and comes up with an alternative to the concept and word of "gene." (Thu, 02 Jul 2009 05:18:03 GMT)
Special Data Needs Special Treatment
At his Genetic Future blog, Daniel MacArthur gives his two cents on a recent perspective article in Nature Reviews Genetics that discusses the ethical challenges of whole genome sequencing . MacArthur dissects the possible difficulties of getting the right data into the hands of consumers. (Thu, 02 Jul 2009 05:18:13 GMT)
Getting to Know the Gibbon
A new paper out in PLoS Genetics today outlines a high-resolution synteny map that illustrates disruptions between the human and gibbon genomes. Authors include Sanger's Jane Rogers, Baylor's Aleksandar Milosavljevic, and Pieter de Jong of the Children's Hospital of Oakland Research Institute. (Thu, 02 Jul 2009 05:18:23 GMT)
N.C. Research Campus showcases its equipment, expertise
By Emily Ford eford@salisburypost.com KANNAPOLIS — The David H. Murdock Research Institute has started showcasing the array of equipment and experti ... (Thu, 02 Jul 2009 08:00:09 GMT)
£4m mental health genetics centre
A research centre which will use genetics to study conditions ranging from schizophrenia to dyslexia is being launched. (Thu, 02 Jul 2009 11:11:04 GMT)
Roche NimbleGen CNV Arrays Selected for Landmark Korean Copy Number Variation Study
MADISON, Wis.----Roche NimbleGen has entered into a partnership with the Korea Centers for Disease Control and Prevention and Macrogen, Inc. to conduct an 8-month intensive Copy Number Variation study of Korean individuals. (Thu, 02 Jul 2009 12:00:00 GMT)
Genome Canada Appoints New Chair of the Board
OTTAWA, ONTARIO--(Marketwire - July 2, 2009) - Genome Canada is pleased to announce the appointment of Dr. C. Thomas Caskey as Chair of the Board of Directors, effective June 18, 2009. Dr. Caskey has been a member of Genome Canada's Board of Directors for a number of years and has served in various capacities on a number of committees. He was appointed Vice-Chair in 2008. Dr. Caskey currently ... (Thu, 02 Jul 2009 12:18:57 GMT)
New e-Science Service Could Accelerate Cancer Research
The University of Manchester and the European Molecular Biology Laboratory's European Bioinformatics Institute (EMBL-EBI) have launched a major new e-science resource for biologists which could accelerate research into treatments for H1N1 flu and cancer. Biocatalogue. (Thu, 02 Jul 2009 12:24:54 GMT)
New biomarker method may help detection of cancer in early stage
A team of researchers has demonstrated that a new method for detecting and quantifying protein biomarkers in body fluids may ultimately make it possible to screen multiple biomarkers in hundreds of patient samples, thus ensuring that only the strongest biomarker candidates will advance down the development pipeline. (Thu, 02 Jul 2009 12:48:25 GMT)
Q&A: U of Zurich Team Develops Protein Inference Method to Eliminate Shotgun Proteomics Ambiguities
In a study published June 22 online in Genome Research , researchers describe a new peptide classification and protein inference method that helped them identify around 3,500 proteins in pollen — around 13 times the previously reported pollen proteome. (Thu, 02 Jul 2009 14:32:53 GMT)
Extensive and Rapid Diagnostic Assay for Herpesviral Infections in the Central Nervous System
HELSINKI, FINLAND--(Marketwire - July 2, 2009) - Mobidiag's CE-IVD-marked Prove-itT Herpes-test helps the clinician in targeting antiviral treatment correctly for patients with severe herpesviral infections Helsinki, Finland - June 2, 2009 - Finnish biotech company Mobidiag announces CE-marked herpesvirus microarray for rapid In Vitro Diagnostics (IVD) of life-threatening central nervous system ... (Thu, 02 Jul 2009 14:33:04 GMT)
$500,000 Gruber Neuroscience Prize Awarded To Hall, Rosbash And Young
The 2009 Neuroscience Prize of The Peter and Patricia Gruber Foundation is being awarded to Jeffrey Hall, professor of neurogenetics at the University of Maine; Michael Rosbash, professor and director of the National Center for Behavioral Genomics at Brandeis University; and Michael Young, professor and head of the Laboratory of Genetics at Rockefeller University. (Thu, 02 Jul 2009 15:09:42 GMT)
Dawkins and Venter: Their Egos Do Fit in the Same Room
Richard Dawkins stops by to see Craig Venter and gets a tour of his sequencing facility while chatting about the Human Genome Project and how the technology has changed in the intervening years. (Thu, 02 Jul 2009 15:47:53 GMT)
Scan of the Sample
And now for a moment of shameless self-promotion: if you haven't seen our new sister blog on clinical labs, The Sample , check it out. Some recent items: The search for a director for Kaiser Permanente's molecular genetics lab has dragged on for at least five weeks . The director, should they ever find one, will oversee the lab's "high-complexity molecular genetics mutation studies for an ... (Thu, 02 Jul 2009 15:48:13 GMT)
Back From the Brink, But Hurtling Toward Another One
The Amur tiger may have bounced back from the brink of extinction (there are now 500 in the wild and 421 in captivity, up from the 1940s low of 20 to 30) but a new study in Molecular Ecology says that their genetic diversity is the lowest ever measured for wild tigers, says the BBC. Further compounding the problem is that there are two populations of the wild tiger that do not intermingle as ... (Thu, 02 Jul 2009 15:48:23 GMT)
Illumina falls after 2Q revenue misses estimates
Shares of Illumina Inc. sank Thursday after the genetic analysis instrument maker said revenue in the second quarter fell short of its own forecast and Wall Street estimates. (Thu, 02 Jul 2009 16:00:37 GMT)
This Week in Nature
Three genome-wide association studies published in Nature 's early online edition show that many common variants contribute to increased risk for developing schizophrenia -- not just large, rare structural variations. (Thu, 02 Jul 2009 16:02:53 GMT)
Research reveals what drives lung cancer's spread
( Memorial Sloan-Kettering Cancer Center ) A new study by researchers at Memorial Sloan-Kettering Cancer Center reveals the genetic underpinnings of what causes lung cancer to quickly metastasize, or spread, to the brain and the bone -- the two most prominent sites of lung cancer relapse. The study will be published online in the journal Cell on July 2. (Thu, 02 Jul 2009 16:13:28 GMT)
UCLA scientists find molecular differences between embryonic stem cells and reprogrammed skin cells
UCLA researchers have found that embryonic stem cells and skin cells reprogrammed into embryonic-like cells have inherent molecular differences, demonstrating for the first time that the two cell types are clearly distinguishable from one another. (Thu, 02 Jul 2009 16:13:38 GMT)
Embryonic stem cells, reprogrammed skin cells have inherent differences
(PhysOrg.com) -- UCLA researchers have found that embryonic stem cells and skin cells reprogrammed into embryonic-like cells have inherent molecular differences, demonstrating for the first time that the two cell types are clearly distinguishable from one another. (Thu, 02 Jul 2009 16:33:17 GMT)
Meetings and Deadlines
Jul 17-19 Genetic Alliance Annual Meeting Genetic Alliance Bethesda, Md. Genetics (Thu, 02 Jul 2009 16:47:56 GMT)
AMP Lays Out Five 'Key' Points for US Gov't to Consider When Revamping Health-Care System
The Association for Molecular Pathology earlier this week released five "key principles" the federal government should keep in mind as it tries to revamp the nation’s health-care system. (Thu, 02 Jul 2009 18:17:53 GMT)
Interleukin Sells Nutrition Branch for $4.6M
NEW YORK (GenomeWeb News) – Interleukin Genetics said today that it has sold its Alan James Group business to Pep Products, a subsidiary of Nutraceutical Corporation, for around $4.6 million in cash. (Thu, 02 Jul 2009 18:47:53 GMT)
BlueGnome to Market Rubicon Technology for IVF Studies
NEW YORK (GenomeWeb News) – BlueGnome will market Rubicon Genomics' technology along with its microarray-based aneuploidy chromosome screening and detection systems under a new non-exclusive agreement, Rubicon said today. (Thu, 02 Jul 2009 18:48:57 GMT)
CDRH, on the Move in Maryland, Limits Days for Test Submissions
The FDA's Center for Devices and Radiological Health expects to complete relocating to its new Maryland digs Aug. 3, and is urging researchers not to file regulatory submissions on certain days. (Thu, 02 Jul 2009 19:03:13 GMT)
Genetic sequencing gets personal
Price competition is coming to the rarified world of genome sequencing. (Thu, 02 Jul 2009 19:23:45 GMT)
CLC bio Expands Next Generation Sequencing Solutions with Digital Gene Expression by Tag Profiling
AARHUS, Denmark----CLC bio today announced the release of new versions of the desktop application CLC Genomics Workbench, version 3.6 and the award-winning enterprise platform CLC Genomics Server, version 1.6. (Thu, 02 Jul 2009 19:43:00 GMT)
UK's MRC Funds Fourth High-Throughput Sequencing Hub in Oxford with Over $3M
The UK's Medical Research Council said last week that it is funding a high-throughput sequencing center, based at the Wellcome Trust Centre for Human Genetics in Oxford, with approximately £2 million ($3.3 million), adding to more than £7 million in funding for three other UK-based sequencing hubs that the MRC announced this spring. (Thu, 02 Jul 2009 20:32:53 GMT)
Scientists Find Molecular Differences Between Embryonic Stem Cells and Reprogrammed Skin Cells
UCLA researchers have found that embryonic stem cells and skin cells reprogrammed into embryonic-like cells have inherent molecular differences, demonstrating for the first time that the two cell types are clearly distinguishable from one another.The data from the study suggest that embryonic stem cells and the reprogrammed cells, known as induced pluripotent stem (iPS) cells, have overlapping ... (Thu, 02 Jul 2009 20:44:36 GMT)
Study Reveals What Drives Lung Cancer's Spread
A new study by researchers at Memorial Sloan-Kettering Cancer Center (MSKCC) reveals the genetic underpinnings of what causes lung cancer to quickly metastasize, or spread, to the brain and the bone – the two most prominent sites of lung cancer relapse. (Thu, 02 Jul 2009 20:44:48 GMT)
Osmetech Raises $8.6M Through Private Placement
NEW YORK (GenomeWeb News) – British molecular diagnostics firm Osmetech has raised £5.2 million ($8.6 million) through a private placement of around 262 million new ordinary shares at a price of 2p each. (Thu, 02 Jul 2009 22:17:53 GMT)
'Jumping gene' diminishes the effect of a new type 2 diabetes risk gene
Research has identified a new gene associated with diabetes, together with a mechanism that makes obese mice less susceptible to diabetes. A genomic fragment that occurs naturally in some mouse strains diminishes the activity of the risk gene Zfp69. The researchers also found that the corresponding human gene (ZNF642) is especially active in overweight individuals with diabetes. The results of ... (Fri, 03 Jul 2009 00:13:17 GMT)
Major new e-science resource for biologists
The University of Manchester and the European Molecular Biology Laboratory's European Bioinformatics Institute (EMBL-EBI) have launched a major new e-science resource for biologists - which could accelerate research into treatments for H1N1 flu and cancer. (Fri, 03 Jul 2009 00:42:16 GMT)
Health care brings architect to Arizona
Rebecca Olson's road to Phoenix was a bit twisty. But along the way, she obtained plenty of experience in health-care architecture, her specialty as associate principal with Phoenix-based Westlake Reed Leskosky. (Fri, 03 Jul 2009 00:52:33 GMT)
OncQuest Labs launches K-RAS Mutation Analysis for diagnosis of colorectal & lung cancers
OncQuest Laboratories Ltd., a pioneer in Indian oncology clinical testing, has introduced the K-RAS Mutation Analysis for determining therapeutic response of the targeted therapies in colorectal and lung cancers. (Fri, 03 Jul 2009 02:49:08 GMT)
Molecular Differences Found Between Embryonic Stem Cells And Reprogrammed Skin Cells
Researchers have found that embryonic stem cells and skin cells reprogrammed into embryonic-like cells have inherent molecular differences, demonstrating for the first time that the two cell types are clearly distinguishable from one another. (Fri, 03 Jul 2009 04:22:54 GMT)
Would that Be Doping, or Just Perfect Genetics?
OK, that may be a little harsh, but it's the theme of this Discover article about how advances in gene therapy and genetic manipulation may ultimately change the concept of athletes. (Fri, 03 Jul 2009 05:18:04 GMT)
Score One for Open Access
Publishing company Springer has acquired BioMed Central , the largest open access publisher with more than 180 peer-reviewed journals. Springer's Derk Haank said in a statement , "This acquisition reinforces the fact that we see open access publishing as a sustainable part of STM publishing, and not an ideological crusade." (Fri, 03 Jul 2009 05:18:10 GMT)
Francis vs. the Atheists: This Won't Be Pretty
At Framing Science , Matthew Nisbet uses today's premier of the movie Expelled to caution atheist scientists about going too far. He excerpts a Pew interview with Francis Collins , who breaks down why "the current crowd of seemingly angry atheists, who are using science as part of their argument that faith is irrelevant, do not speak for us," Collins says. (Fri, 03 Jul 2009 05:18:22 GMT)
CLC Bio Reveals Biocomputing Solution At ISMB 2009 In Stockholm
Today, at the 17th international conference on Intelligent Systems for Molecular Biology (ISMB) and 8th European Conference on Computational Biology (ECCB) in Stockholm, Sweden, CLC bio has revealed their first turnkey biocomputing solution for analyzing and visualizing Next Generation Sequencing data, called CLC Genomics Machine. (Fri, 03 Jul 2009 09:31:10 GMT)
What prompts lung cancer to spread
Washington, July 3: Researchers from Memorial Sloan-Kettering Cancer Centre claim to have identified a cellular pathway that is involved in spread of lung cancer. (Fri, 03 Jul 2009 10:48:54 GMT)
Research Reveals What Drives Lung Cancer's Spread
A new study by researchers at Memorial Sloan-Kettering Cancer Center (MSKCC) reveals the genetic underpinnings of what causes lung cancer to quickly metastasize, or spread, to the brain and the bone the two most prominent sites of lung cancer relapse. The study will be published online in the journal Cell on July 2. (Fri, 03 Jul 2009 12:09:42 GMT)
What Drives Lung Cancer's Spread?
A new study reveals the genetic underpinnings of what causes lung cancer to quickly metastasize, or spread, to the brain and the bone -- the two most prominent sites of lung cancer relapse. (Fri, 03 Jul 2009 12:23:15 GMT)
Risk Of Liver Cancer In Women With Hepatitis B Virus Infection Varies With Number Of Pregnancies
Risk for hepatocellular carcinoma, a primary malignancy of the liver, was statistically significantly higher among women with hepatitis B virus (HBV) infection than among women without the virus, according to a new study. (Fri, 03 Jul 2009 12:23:41 GMT)
Cell Pathway May Be Key to Lung Cancer's Spread
FRIDAY, July 3 (HealthDay News) -- U.S. researchers say they've found a major cellular flaw that may drive the rapid spread of relapsed lung cancer. (Fri, 03 Jul 2009 13:02:37 GMT)
Cell Pathway May Be Key to Lung Cancer's Spread
Researchers express hope that finding will lead to treatments (Fri, 03 Jul 2009 13:31:33 GMT)
Genome-Wide Screen Turns Up Primate-Specific Genes
NEW YORK (GenomeWeb News) – In a paper scheduled to appear online this week in the Proceedings of the National Academy of Sciences , researchers from the Genome Institute of Singapore and Wayne State University used a genome-wide screen to try to fish out primate-specific sequences in the human genome. (Fri, 03 Jul 2009 13:47:59 GMT)
CFI's 'Omics Grants Broad in Scope
NEW YORK (GenomeWeb News) – The nearly C$670 million ($576.8 million) that the Canada Foundation for Innovation recently pumped into research projects and infrastructure will fund a range of genomics and proteomics studies and institutes spread across the nation. (Fri, 03 Jul 2009 13:48:09 GMT)
Research and Markets: Fundamental Principles of Bayesian Analysis of Gene Expression Data Explored
DUBLIN----Research and Markets has announced the addition of John Wiley and Sons Ltd's new report "Bayesian Analysis of Gene Expression Data" to their offering. (Fri, 03 Jul 2009 14:40:00 GMT)
No, This Is Not About Paternity Testing
Misha Angrist alerts readers about an upcoming conference at NIH focused on improving accuracy and standards for family histories. The meeting's open to anyone and will be held August 24-26 at NIH, and will also be webcast. (Fri, 03 Jul 2009 15:03:48 GMT)
Science and Religion, Science and Atheism
John Hawks has a post linking out to a survey published in the Guardian and conducted by the British Council, which polled 10,000 people in 10 countries to determine whether they believe in evolution, whether it should be taught, and whether beliefs in religion and evolution can be held simultaneously. (Fri, 03 Jul 2009 15:17:53 GMT)
S. Brenner on C. elegans
Over at Flies & Bikes, GrumpyBob has a post on a perspectives piece from Sydney Brenner in the latest issue of Genetics . "This brief article ... presents an account of the origins of Caenorhabditis elegans research, by the beast's main man," the blogger writes. (Fri, 03 Jul 2009 15:18:03 GMT)
In Brief This Week: Roche NimbleGen; Aushon BioSystems; Saladax Biomedical; Mobidiag; Enigma Diagnostics
NEW YORK (GenomeWeb News) – Roche NimbleGen said this week that it has entered into a partnership with the Korea Centers for Disease Control and sequencing services firm Macrogen to conduct an eight-month copy number variation study of Korean individuals. (Fri, 03 Jul 2009 15:32:53 GMT)
Cardiff Univ. Uses $6.6M for Neuro-Genetics and Genomics Center
NEW YORK (GenomeWeb News) – Cardiff University in Wales has established a new center to study the genetic underpinnings of mental illnesses, and said that it will be funded with over £4 million ($6.6 million) from sources within the UK and from its own coffers. (Fri, 03 Jul 2009 15:33:13 GMT)
This Week in Science
In news this week, scientists and universities are asking US Congress "not to expand a $2 billion research program for small businesses " because it would likely cut money that could otherwise go toward research projects. (Fri, 03 Jul 2009 15:33:23 GMT)
Pharma industry is worth Rs 78,000 crore: Economic Survey
The pharma industry in the country has grown from mere Rs 1500 crore turnover in 1980 to over Rs 78,000 crore in 2008, with about 10 per cent share in the volume of global production, according to the latest Economic Survey which called for decontrolling of prices. (Sat, 04 Jul 2009 02:48:45 GMT)
Take That, SciFoo
Pimm blogger Attila Csordas writes about the attempt by the BioTwitterer community to organize a biology-focused "unconference" that would take place in the Bay Area around the same time as SciFoo Camp. The BioBarCamp conference would bring together life scientists in the areas of biotechnology, personalized genomics and medicine, and bioinformatics. (Sat, 04 Jul 2009 05:17:53 GMT)
This Week in Science
Stem cell researchers Chad Cowan, Douglas Melton, and Alan Trounson joined Jeanne Loring in issuing statements against the University of Wisconsin's three human stem cell patents, says a Science news story. (Sat, 04 Jul 2009 05:18:03 GMT)
At the Very Least, You Could Send a Thank-You E-card
Over at Open Access News , Peter Suber notes the launch of Molecular Biology Databases , which he describes as "a website to evaluate the openness of databases in molecular biology." (Sat, 04 Jul 2009 05:18:13 GMT)
Norfolk genome centre officially opened
Breeding new drought resistant crops and protecting livestock from exotic diseases are just two of the areas which could be developed by staff at the new £13.5m national Genome Analysis Centre, which was officially opened in Norfolk yesterday . Environment correspondent TARA GREAVES reports. (Sat, 04 Jul 2009 05:36:09 GMT)
Schizophrenia And Bipolar Disorder Share Genetic Roots
A trio of genome-wide studies - collectively the largest to date - has pinpointed a vast array of genetic variation that cumulatively may account for at least one third of the genetic risk for schizophrenia. One of the studies traced schizophrenia and bipolar disorder, in part, to the same chromosomal neighborhoods. (Sat, 04 Jul 2009 10:07:31 GMT)
UCLA Scientists Find Molecular Differences Between Embryonic Stem Cells And Reprogrammed Skin Cells
UCLA researchers have found that embryonic stem cells and skin cells reprogrammed into embryonic-like cells have inherent molecular differences, demonstrating for the first time that the two cell types are clearly distinguishable from one another. (Sat, 04 Jul 2009 10:09:52 GMT)
Students try their hands at targeting tumors with potent computing power
A group of budding scientists got a chance Friday to use top-of-the- line computer technology to develop plans for treating cancer. (Sat, 04 Jul 2009 11:06:05 GMT)
Embryonic stem cells and reprogrammed skin cells are clearly distinguishable
Washington, July 4: Researchers at the University of California-Los Angeles (UCLA) have shown that there are certain molecular differences between embryonic stem cells and skin cells skin cells reprogrammed into embryonic-like cells. (Sat, 04 Jul 2009 16:19:23 GMT)
Bomb squad neutralizes two soda pop bottle devices found at OSU
Bottles weren’t lethal, but could cause a lot of damage (Sun, 05 Jul 2009 02:26:45 GMT)
Lighting Up Plants' Lives
In more open-access news, Cold Spring Harbor Protocols posted a freely-accessible article as part of their current issue. This paper contains suggestions for how plant biologists can bypass plants’ cell walls and natural fluorescence to use green fluorescent protein in imaging various plant tissues. (Sun, 05 Jul 2009 06:18:09 GMT)
Cloudy With a Chance of HPC
Like the beginning of a rainstorm as the first few drops go from lonely pitter-pats to a torrential downpour, cloud computing has been steadily picking up momentum and announcing itself loud and clear. (Sun, 05 Jul 2009 18:03:13 GMT)
British teenagers in Romanian hospital with swine flu
Eight pupils on exchange programme from Kent school had been working with children in north-eastern city of Iasi Eight UK school pupils are in hospital in north-east Romania with swine flu, a British embassy official said today. Raluca Bragarea, the embassy communications officer, said the group had arrived in Romania on 25 June as part of an annual exchange programme and had been working with ... (Sun, 05 Jul 2009 18:16:21 GMT)
NASA Spaceline 5 June 2009 Current Space Life Science Awareness
NASA Spaceline 5 June 2009 Current Space Life Science Awareness (Sun, 05 Jul 2009 23:30:10 GMT)
New UK national genome centre
A new UK national genome centre was officially opened by Nobel Laureate and genome pioneer Prof Sir John Sulston and the Lord-Lieutenant of Norfolk. (Sun, 05 Jul 2009 23:31:06 GMT)
TGen tapped for $190 mil 'biobank' project overseas
Luxembourg has tapped TGen in Phoenix to create a ''biobank'' that will store blood and tissue samples for scientists to access as they research diseases such as lung cancer and heart disease. (Mon, 06 Jul 2009 01:10:55 GMT)
MIDA upbeat Aussie firms will up investment (Business Times
AUSTRALIAN business leaders have been reminded Malaysia still provided attractive business opportunities despite the global economic downturn. (Mon, 06 Jul 2009 04:11:32 GMT)
New UMBI research collaborative could attract more federal funds
Leading stem cell and genomics researchers from the University of Maryland, Baltimore may move into downtown Baltimore’s Columbus Center next year to collaborate with researchers at the University of Maryland Biotechnology Institute. (Mon, 06 Jul 2009 04:11:40 GMT)
Lost promise: Can region’s shrinking biotech sector bounce back after big hits?
A quarter-century ago, local scientists embarked on a journey to map out the human genome. By 2000, their discoveries would end up mapping out the future of Montgomery County’s biotech community. (Mon, 06 Jul 2009 04:13:00 GMT)
Other News
MELBOURNE, July 6 (Bernama) -- Australian business leaders have been reminded Malaysia still provided attractive business opportunities despite the global economic downturn. (Mon, 06 Jul 2009 04:16:01 GMT)
Aussie firms told Malaysia still attractive business target
MELBOURNE, July 6 — Australian business leaders have been reminded that Malaysia still provided attractive business opportunities despite the global economic downturn. Speaking at an Australia-Malaysia business networking function over the weekend, Jaswant Singh, the director of the Malaysian Industrial Development Authority in Australia (MIDA Australia), said Malaysia's economic development was ... (Mon, 06 Jul 2009 05:06:26 GMT)
Genetic ’clue’ to mental disorders
MENTAL health disorder is caused by the combined effect of thousands of variants in genes, Welsh scientists have found. (Mon, 06 Jul 2009 05:21:44 GMT)
Bomb squad neutralizes two soda pop bottle devices found at OSU
Bottles weren’t lethal, but could cause a lot of damage (Mon, 06 Jul 2009 05:45:36 GMT)
We Predict a Google Genetic Map
Over at Genetic Future, Daniel MacArthur discusses the recent Lao paper from Current Biology that genotyped 2,514 people from 23 different European subpopulations. (Mon, 06 Jul 2009 06:17:53 GMT)
This Week in Science
In five years, Biopolis in Singapore has grown to 1,000 scientists, and it’s not lacking in scientific output: the number of papers produced at the flagship Institute of Molecular and Cell Biology grew from 82 in 2000 to 165 in 2006, and Singapore’s Genome Institute became the first in the world to sequence the SARS virus in 2003. However, critics there are beginning to argue whether the current ... (Mon, 06 Jul 2009 06:18:13 GMT)
A Bright and Shiny Future -- Wait, No
Over on Aetiology, Tara Smith discusses the future of graduate students and post-docs – it is not looking so bright. She quotes a recent Chronicle of Higher Education article that says that the long training time, job shortages in academia, and the daunting competition for research grants is a bit of a turn-off. (Mon, 06 Jul 2009 06:18:23 GMT)
Aussie firms told Malaysia still attractive business target
MELBOURNE, July 6 — Australian business leaders have been reminded that Malaysia still provided attractive business opportunities despite the global economic downturn. Speaking at an Australia-Malaysia business networking function over the weekend, Jaswant Singh, the director of the Malaysian Industrial Development Authority in Australia (MIDA Australia), said Malaysia's economic development was ... (Mon, 06 Jul 2009 06:42:41 GMT)
TGen strengthens Luxembourg link with new CEO
Scientists from the Translational Genomics Research Institute were instrumental in attracting the new CEO for the Integrated Biobank of Luxembourg. (Mon, 06 Jul 2009 07:12:05 GMT)
Bioinformatics Expert Dr. Jiaan Yang Joins Sundia MediTech With Innovative PFSC Technology
Sundia MediTech Company, a leading integrated pharmaceutical and biotech R&D outsourcing company in Shanghai, China announced today that Sundia has acquired Protein Folding Shape Code technology for doing probe binding site for drug discovery from Microtech Nano LLC, a R&D Company in Indianapolis, IN, USA. (Mon, 06 Jul 2009 11:00:00 GMT)
MIDA upbeat Aussie firms will up investment (Business Times
AUSTRALIAN business leaders have been reminded Malaysia still provided attractive business opportunities despite the global economic downturn. (Mon, 06 Jul 2009 11:13:23 GMT)
(Slightly) New Address for UK's National Genetics Reference Laboratory Manchester
The UK's National Genetics Reference Laboratory Manchester will move into its new digs three days earlier than planned. (Mon, 06 Jul 2009 13:35:50 GMT)
Helicos Says Transcriptome Quantification Method Promises Accurate Results at Low Cost
Digital gene expression analysis on the Helicos Genetic Analysis system complements full-length RNA sequencing methods and promises to be more accurate and less expensive than similar methods on other sequencing platforms because the sample prep is simple and avoids amplification, according to the company. (Mon, 06 Jul 2009 14:32:55 GMT)
Virginia Bioinformatics Institute to develop petascale computer modeling capabilities
( Virginia Tech ) The goal of the proposal is to use new computer technology to study events like disease pandemics, financial crises, as well as the spread of opinions, attitudes or social beliefs, through populations on a global scale. Current agent-based computer models can simulate the spread of a disease like influenza through a population the size of the United States. Petascale modeling ... (Mon, 06 Jul 2009 14:37:18 GMT)
Proteome Sciences, Millipore Ink Alzheimer's Assay Deal
NEW YORK (GenomeWeb News) – Proteome Sciences and Millipore jointly announced today that they will collaborate on the development of multiplex immunoassays for Alzheimer's disease research. (Mon, 06 Jul 2009 14:48:10 GMT)
Precision BioSciences Says USPTO to Re-examine Cellectis Patents
NEW YORK (GenomeWeb News) – Precision BioSciences today said that the US Patent and Trademark Office is reexamining two patents that have been licensed to Cellectis and that are part of ongoing litigation between the two firms. (Mon, 06 Jul 2009 14:48:21 GMT)
UK Opens Norwich Genomics Center
NEW YORK (GenomeWeb News) – The United Kingdom has officially opened a new center for genomics research in Norwich that will conduct research on plants, animals, and microbes for medical, bioenergy, and livestock applications, the Biotechnology and Biological Sciences Research Council said on Friday. (Mon, 06 Jul 2009 14:48:32 GMT)
In Print
Ay F, Kahveci T, DE Crécy-Lagard V. A fast and accurate algorithm for comparative analysis of metabolic pathways . [ J Bioinform Comput Biol . 2009 Jun;7(3):389-428]: Describes an algorithm for pairwise alignment of metabolic pathways. (Mon, 06 Jul 2009 16:17:53 GMT)
Researchers find genetic key to breast cancer's ability to survive and spread
( Memorial Sloan-Kettering Cancer Center ) New research led by investigators at Memorial Sloan-Kettering Cancer Center sheds light on a genetic function that gives breast cancer cells the ability to survive and spread to the bone years after treatment has been administered. The findings support the study of therapies that target this survival capacity and force the death of latent breast cancer ... (Mon, 06 Jul 2009 16:19:00 GMT)
Ready for relapse: Molecule helps breast cancer cells to survive in the bone marrow
( Cell Press ) Patients who survive an initial diagnosis of breast cancer often succumb to the disease years later when the cancer shows up in a different part of the body. Now, scientists have identified key signals that support the long term survival of breast cancer cells after they have spread to the bone marrow. (Mon, 06 Jul 2009 16:29:00 GMT)
Researchers Find Genetic Key to Breast Cancer's Ability to Survive and Spread
New research led by investigators at Memorial Sloan-Kettering Cancer Center sheds light on a genetic function that gives breast cancer cells the ability to survive and spread to the bone years after treatment has been administered. The findings support the study of therapies that target this survival capacity and force the death of latent breast cancer cells before they get a chance to ... (Mon, 06 Jul 2009 16:43:02 GMT)
Biomarkers Take Center Stage
It often seems that nearly everyone is on the search for a biomarker, whether it is for Alzheimer's disease, diabetes, certain types of cancer, or schizophrenia. The search, however, isn't always easy and can be fraught with challenges. (Mon, 06 Jul 2009 17:02:53 GMT)
NHS 'ill-prepared' for genetic testing
Genetic testing is set to revolutionise medicine but the NHS is ill-prepared to adopt it, a House of Lords committee has warned. (Mon, 06 Jul 2009 17:09:25 GMT)
Dogs, humans, put heads together to find cure for brain cancer
Pinpointing the genes involved in human brain cancer can be like looking for a needle in a haystack, and sometimes the needle you find may not be the right one. By comparing human and canine genomes, researchers at North Carolina State University have discovered that a gene commonly believed to be involved in meningiomas-tumors that affect the meninges, or thin covering, of the human brain and ... (Mon, 06 Jul 2009 17:50:14 GMT)
Dogs, Humans, Put Heads Together To Find Cure For Brain Cancer
Pinpointing the genes involved in human brain cancer can be like looking for a needle in a haystack, and sometimes the needle you find may not be the right one. (Mon, 06 Jul 2009 18:21:05 GMT)
New Product Watch
Mobidiag last week said that it has CE marked its Prove-it Herpes virus microarray for in vitro detection of central nervous system infections. The Helsinki, Finland-based firm said the CE mark ensures the safety of the product in clinical use and opens European markets for its test. (Mon, 06 Jul 2009 18:33:50 GMT)
Better than Gold? GWC Receives $100K ARRA Grant to Develop New Substrate for Protein Arrays
GWC Technologies is taking advantage of Washington's stimulus efforts to develop a new protein array technology. (Mon, 06 Jul 2009 18:47:53 GMT)
Stocks of Several Tool Vendors Rose Sharply in First Half of '09
NEW YORK (GenomeWeb News) – The stocks of several firms in the GenomeWeb Daily News Index rose sharply — a couple of them rising nearly 400 percent — during the first six months of 2009. (Mon, 06 Jul 2009 19:02:53 GMT)
NIH to Fund Inner Ear Proteomics Studies
NEW YORK (GenomeWeb News) – The National Institute on Deafness and Other Communication Disorders will fund scientists seeking to use proteomics to study inner ear development and diseases. (Mon, 06 Jul 2009 19:33:44 GMT)
Tougher Controls Sought For DNA Ancestry Testing
As the popularity of take-home DNA kits to trace ancestry or calculate the risk for serious medical conditions grows, there is an increasingly critical need for federal oversight of "direct-to consumer" genetic testing, as well as of the use of DNA samples for research, according to researchers from the University of California, Berkeley, and several other academic institutions.In the past year, ... (Mon, 06 Jul 2009 20:15:29 GMT)
Stanford Alzheimer's Research Pinpoints Antibodies That May Prevent Disease
STANFORD, Calif.----Antibodies to a wide range of substances that can aggregate to form plaques, such as those found in Alzheimer's patients, have been identified in the blood and cerebrospinal fluid of healthy people. (Mon, 06 Jul 2009 21:00:00 GMT)
Stanford Alzheimer's research pinpoints antibodies that may prevent disease
Antibodies to a wide range of substances that can aggregate to form plaques, such as those found in Alzheimer's patients, have been identified in the blood and cerebrospinal fluid of healthy people. Levels of these antibodies decline with age and, in Alzheimer's patients, with increasing progression of the disease. (Mon, 06 Jul 2009 21:29:12 GMT)
Call on NHS to prepare for rise in genomics
The National Health Service must prepare for huge changes as DNA testing becomes more commonplace in diagnosis and treatment, the House of Lords science committee says in a wide-ranging report on genomic medicine on Tuesday. (Tue, 07 Jul 2009 01:52:32 GMT)
Bay Area lab helps track H1N1 virus
Bay Area researchers are trying to track the H1N1 virus and save lives. (Tue, 07 Jul 2009 02:18:46 GMT)
U of L researches find key protein to kidney disease
Three U of L researchers have helped identify a key protein in the middle of membranous nephropathy. The breakthrough will help the more than 60,000 Americans who suffer from the condition, where the body's immune system attacks its own kidneys. (Tue, 07 Jul 2009 02:55:24 GMT)
Alzheimer's Research Pinpoints Antibodies That May Prevent Disease
Antibodies to a wide range of substances that can aggregate to form plaques, such as those found in Alzheimer's patients, have been identified in the blood and cerebrospinal fluid of healthy people. Levels of these antibodies decline with age and, in Alzheimer's patients, with increasing progression of the disease. (Tue, 07 Jul 2009 03:24:07 GMT)
Research and Markets: Comparison of Pharma Outsourcing Between China and India
DUBLIN----Research and Markets has announced the addition of the "Comparison of Pharma Outsourcing between China and India" report to their offering. (Tue, 07 Jul 2009 05:00:00 GMT)
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