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Bioinformatics News 06/2009 (Page 4)

GlaxoSmithKline Licenses New Version of Rosetta Resolver Software Development Kit (GenomeWeb News)
GlaxoSmithKline has become the first company to license the Rosetta Resolver Software Development Kit version 2.0.

Nanogen Receives US Army Grant to Develop Microarrays as Biowarfare Detection Systems (GenomeWeb News)
Nanogen has been awarded a three-year, $1.5 million grant from the US Army to continue developing NanoChip applications for detecting biological warfare agents and infectious disease agents.

A Chocolate Cake a Day Based on Your Ts, Cs, Gs, and As (GenomeWeb News)
Genomics may not have truly hit the mainstream yet, but never fear -- scams based on supposed genomic discoveries already seem to abound, according to an article in the Guardian . The story reports on companies offering custom diets to people based on their specific genetic variation, saying that people may be able to avoid problems they're genetically susceptible to with these special diet plans.

Risks Of Sharing Personal Genetic Information Online Need More Study, Bioethicists Say (Science Daily)
With just $399 and a bit of saliva in a cup, consumers can learn about their genetic risk for diseases from breast cancer to diabetes. Now, thanks to social networking sites set up by personal genomics companies, they can also share that information with family, friends and even strangers on the Internet. Bonding over a similar genetic background sounds relatively harmless. But according to ...

New Lead For Autoimmune Disease From Chinese Medicine (Science Daily)
A major challenge in treating autoimmune disorders has been suppressing inflammatory attacks on body tissues without generally suppressing immune function. Now, a drug from Chinese medicine shows potential for easing these disorders. In both mice and humans, it selectively inhibits development of Th17 cells, newly-recognized immune cells that were recently implicated in inflammatory bowel ...

Geneart bags contract from MPI for molecular genetics (PharmaBiz)
Geneart AG, global leader in Gene Synthesis and specialist in the field of Synthetic Biology, received a major order from the Max Planck Institute (MPI) for molecular genetics.

Ambry Genetics launches Chromosomal Microarray to offer whole genome analysis (PharmaBiz)
Ambry Genetics launched whole-genome Chromosomal Microarray Analysis (CMA), offering the Ambry CMA: 105K Oligo Array, which is designed to identify chromosomal abnormalities associated with over 270 genetic disorders.

PanGenetics Receives Approval for Clinical Evaluation of Anti-NGF Antibody in Patients with Chronic Pain (Business Wire via Yahoo! Finance)
UTRECHT, The Netherlands & CAMBRIDGE, England----PanGenetics B.V. announced today that the Competent Authority of the Netherlands has approved the Clinical Trials Application for a first-in-man study with antibody PG110.

Cranes Software Subsidiary Proland Software Announces Strategic Partnership With VirusBuster (Business Wire via Yahoo! Finance)
BANGALORE, India & BUDAPEST, Hungary----Cranes Software Subsidiary Proland Software, an IT security company that owns the Protector Plus range of Anti-virus software products has entered into a strategic partnership with VirusBuster, a Hungary-based security solutions provider.

Sirius Genomics Announces 2009 Board of Directors (redOrbit)
VANCOUVER, June 8 /PRNewswire/ - Sirius Genomics, a developer of pharmacogenomic diagnostics, announced that it has elected its 2009 Board of Directors at its recent Annual General Meeting. The six-member Board consists of: Dr.

MDRNA, Inc. Reports Effective Local Delivery of a UsiRNA in an In Vivo Model of Bladder Cancer (Marketwire via Yahoo! Finance)
MDRNA, Inc. announced today in vivo data from a bladder cancer model demonstrating effective localized delivery of a UsiRNA to a solid tumor, thus further expanding the delivery capabilities of the DiLA2 Platform.

ChemGenex's Omacetaxine Shows Activity in Refractory CML (Business Wire via Yahoo! Finance)
MELBOURNE, Australia & MENLO PARK, Calif.----ChemGenex Pharmaceuticals Limited announced that positive, updated data from its phase 2/3 clinical trial study of omacetaxine in chronic myeloid leukemia patients with resistance to multiple tyrosine kinase inhibitors was presented at the 14th Congress of the European Hematology Association in Berlin, Germany on Saturday.

ChemGenex's Omacetaxine Kills Leukemic Stem Cells in Human CML Models (Business Wire via Yahoo! Finance)
MELBOURNE, Australia & MENLO PARK, Calif.----ChemGenex Pharmaceuticals Limited , announced today that the results of pre-clinical research that demonstrated that omacetaxine kills model human leukemic stem cells were presented at the 14th Congress of the European Hematology Association in Berlin, Germany on Sunday.

Signature Scientific Microarray Conference Keynote Speakers Announced (Business Wire via Yahoo! Finance)
SPOKANE, Wash.----The keynote speakers for the 2009 Signature Genomic Laboratories Scientific Microarray Conference have been announced.

Recent Patents of Interest in Proteomics (GenomeWeb News)
US Patent 7,541,578. Microfluidic device and manufacturing method thereof . Inventor: Kuo-Yao Weng. Assignee: Industrial Technology Research Institute

USGS Study Links Estrogen to Fish Immunity (Environmental News Network)
Exposure to estrogen reduces production of immune-related proteins in fish. This suggests that certain compounds, known as endocrine disruptors, may make fish more susceptible to disease.

Univ. of Copenhagen Opens Protein Research Center (GenomeWeb News)
NEW YORK (GenomeWeb News) – The University of Copenhagen has opened a new research center that will focus on protein studies aimed at understanding and treating diseases.

Rosetta Genomics To Present At The Eighth Annual Needham and Company Biotechnology and Medical Technology Conference (Business Wire via Yahoo! Finance)
PHILADELPHIA & REHOVOT, Israel----Rosetta Genomics, Ltd. , an innovative molecular diagnostic company leveraging microRNAs as biomarkers, announced that Amir Avniel, president and chief executive officer, will be presenting a corporate update at the Eighth Annual Needham and Company Biotechnology and Medical Technology Conference on Wednesday, June 10, 2009 at 8:30 a.m., at the New York Palace ...

An FDA Twitter Feed and Facebook Page Will Be Next (GenomeWeb News)
The FDA has a new Transparency Blog , as Bertalan Meskó points out , that will run for the next six months to "discuss various ways in which the Food and Drug Administration (FDA) could provide information to the public about what FDA is doing , the bases for FDA's decisions, and the processes used to make agency decisions."

Fool Me Once… (GenomeWeb News)
In The Scientist PNNL's Steven Wiley explains why he's s at out the mad rush for Challenge Grants . "Although the intent is good, history suggests that these grants will eventually be looked upon as one of the greatest time wasters of the decade," he writes.

Too Much of a Good Thing… (GenomeWeb News)
An article in the June issue of Scientific American takes a brief look at CNVs and how they are no longer considered a "direct cause of disease." CNVs are now considered to be common. "It's not normal to be walking around with the perfect genome," Matthew Hurles says.

Scientists in BC Set to Receive $2.7 Million in Funding (T-Net British Columbia)
Vancouver, BC, June 8, 2009--(T-Net)--At a time when the Canadian economy is under significant pressure, Genome BC is making investments in genomics research groups in British Columbia, which will help position the Province to capture specific and significant future scientific opportunities in the global knowledge-based economy.

EU to Grant $11.7M for Pancreatic Cancer Dx, PGx (GenomeWeb News)
NEW YORK (GenomeWeb News) – The European Commission will give €8.4 million ($11.7 million) to fund research efforts that will use genomics and proteomics to develop new screening techniques for pancreatic cancer.

University of the Sciences Elects Four to Board of Trustees (Newswise)
Four new members were recently elected to serve on the board of trustees of University of the Sciences in Philadelphia. Dr. Frank Baldino, Jr. (Cephalon, Inc.), Daniel K. Fitzpatrick (Citizens Bank); Dr. Donald J. M. Phillips (Vox Medica Holdings, Inc.), and Dominic A. Marasco (Quintiles Commercial/Innovex).

Mobile DNA elements in woolly mammoth genome give new clues to mammalian evolution (EurekAlert!)
( Cold Spring Harbor Laboratory ) The woolly mammoth died out several thousand years ago, but the genetic material they left behind is yielding new clues about the evolution of mammals. In a study published online in Genome Research, scientists have analyzed the mammoth genome looking for mobile DNA elements, revealing new insights into how some of these elements arose in mammals and shaped the ...

Monday, June 8, 2009 (GenomeWeb News)
Enter your login e-mail address. Researchers from the US Department of Agriculture, the University of Maryland, Columbia University, and Roche 454 Life Sciences have sequenced and analyzed the draft genome of Nosema ceranae , a honey bee-parasitizing microsporidian fungus.

DiagnoCure announces second quarter financial results (redOrbit)
Ticker Symbol: CUR Gen-Probe to initiate FDA pivotal clinical study for the PCA3 prostate cancer test QUEBEC CITY, June 8 /PRNewswire-FirstCall/ - DiagnoCure Inc.

Off-the-Shelf Genetic Testing On Display (Technology Review)
The emerging market of direct-to-consumer genetic testing gets down to business.

Luminex Launches Two New Cystic Fibrosis Tests in Europe (Business Wire via Yahoo! Finance)
AUSTIN, Texas----Luminex Corporation , the worldwide leader in multiplexed solutions, today announced that it has launched two new cystic fibrosis tests in Europe, the xTAG® Cystic Fibrosis 39 Kit v2 and xTAG® Cystic Fibrosis 71 Kit v2, as CE IVD Marked products under the European Directive on In Vitro Diagnostic Medical Devices.

J. Craig Venter Institute Uses Isilon IQ to Pioneer Next Generation of Genomic Research (PR Newswire via Yahoo! Finance)
out NAS to Streamline DNA Sequencing Operations, Advancing Fight Against Infectious Disease

Consumer Genetics Show (Fast Company Magazine)
Genetics, this is your mainstream moment! So says conference founder and biotech entrepreneur John Boyce, who points to the rapid drop in DNA-sequencing costs and growing interest in genomics from consumer-goods manufacturers. Boyce says this inaugural show will focus on "the intersection of genetics and the consumer front." Expect to see reps from P&G, Unilever, and insurance companies mingling ...

Mexican Ministry of Agriculture and National Institute for Epidemiology Buy Advalytix AmpliSpeed and Implen ... (Business Wire via Yahoo! Finance)
MUNICH and MEXICO CITY----The Advalytix product team of Olympus, Implen, and AmpliBio jointly announce that the Mexican Ministry of Agriculture awarded AmpliBio a contract for 17 GENE LABs - AmpliBio's turnkey solution for molecular analysis.

MDRNA, Inc. Receives Full FDA Approval of Generic Calcitonin-Salmon Nasal Spray for Osteoporosis (Marketwire via Yahoo! Finance)
MDRNA, Inc. announced today that it has obtained full U.S. Food and Drug Administration approval of its Abbreviated New Drug Application for generic calcitonin-salmon nasal spray for the treatment of osteoporosis and that Par Pharmaceutical Companies, Inc. has launched the product.

Reportlinker Adds Genetics Bundle (Business Wire via Yahoo! Finance)
NEW YORK----Reportlinker.com announces that a new market research report is available in its catalogue.

Canary Funds Early Cancer Center at Stanford (GenomeWeb News)
NEW YORK (GenomeWeb News) – Stanford University will use a $15 million commitment from the Canary Foundation, along with $5 million of its own funds, to start a cancer research center focused on using proteomics and imaging techniques to find ways to identify cancer earlier.

MDRNA, Inc. Receives Full FDA Approval of Generic Calcitonin-Salmon Nasal Spray for Osteoporosis (Marketwire)
Par Pharmaceutical Companies, Inc. Launches Product

This Week in PNAS (GenomeWeb News)
Scientists at the the University of Texas Southwestern Medical Center and Chinese Academy of Sciences in Beijing collaborated on a study published this week in the early online edition of PNAS that looked at phosphorylation events of the Neurospora core circadian protein FRQ . Using mass spec, they identified 43 FRQ phosphorylation sites in vivo and another 33 by in vitro kinase assays.

All Personal Genomics, All the Time (GenomeWeb News)
The Consumer Genetics Show has kicked off in Boston. Tech Review says that it is focusing on "what's possible with today's technology, as well as grapple with the controversies that have grown along with the field."

Benching bases (The Scientist)
How to do heavy computational lifting in genomes and transcriptomes

Minding the human genome gap (The Scientist)
New technologies are helping to fill in remaining gaps in the Human Genome Project's sequence. But is it worth the effort?

PatientsLikeMe Teams Up With 23andMe to Help Parkinson's Patients (Marketwire via Yahoo! Finance)
PatientsLikeMe, the first community-based personalized medicine platform for people with life-changing conditions, and 23andMe, the world's leading personal genomics company, announce a partnership today to help people with Parkinson's disease. PatientsLikeMe is teaming with 23andMe on its effort to recruit 10,000 people with Parkinson's for a massive study of the disease, and give patients a ...

Direct-To-Consumer Genetics Testing Makes a Splash In Boston (Slashdot)
eldavojohn writes "MIT's Technology Review has the scoop on the first annual Consumer Genetics Show starting today in Boston and it looks like the rage these days is genetic testing sans the middle-man physician. And it's getting more prevalent and more available: 'A number of companies offering direct-to-consumer genetic testing have cropped up in the past two years to capitalize on these ...

Researchers identify new risk factor gene for rheumatoid arthritis (EurekAlert!)
( North Shore-Long Island Jewish (LIJ) Health System ) Feinstein Institute for Medical Research and a team of collaborators from across the country have identified a new risk factor gene for rheumatoid arthritis. The gene, dubbed REL, is a member of the NF-B family. The NF-B family seems to have a big hand in regulating the body's immune response.

New Products (GenomeWeb News)
CLC Bio has released version 3.5 of CLC Genomics Workbench , a desktop application, and version 1.5 of CLC Genomics Server , an enterprise platform. Both products are used to analyze and visualize next-generation sequencing data.

Papers of Note (GenomeWeb News)
Quantitative deep sequencing reveals dynamic HIV-1 escape and large population shifts during CCR5 antagonist therapy in vivo. Tsibris AM, Korber B, Arnaout R, Russ C, Lo CC, Leitner T, et al.

New Product Watch (GenomeWeb News)
The new scanner acquires two-color fluorescent array image data down to 2-micron pixel resolution and generates high-quality image files for subsequent data analysis, Roche said.

Affy to Debut Benchtop System Next Year to Reach Lower-Throughput Labs (GenomeWeb News)
Affymetrix next year will introduce a benchtop instrument that will target "lower-throughput labs with limited capital budgets, users without access to core facilities, price-sensitive markets, and RT-PCR users looking to access the whole genome," according to a company official.

Ambry Genetics Uses Baylor-Designed Chip to Enter Array-Based Cyto-Testing Market (GenomeWeb News)
Ambry Genetics, a clinical-service lab based in Aliso Viejo, Calif., last week debuted its chromosomal microarray analysis service, thereby entering a growing market dominated by Baylor College of Medicine, Signature Genomic Laboratories, and CombiMatrix Molecular Diagnostics.

GenomeBC Grants $2.4M for New Genomics Studies (GenomeWeb News)
NEW YORK (GenomeWeb News) – Canadian researchers will receive C$2.7 million (US$2.4 million) from a new round of grants from Genome British Columbia to use genomics-based research methods to pursue a range of biomedical, environmental, disease, and forestry-related studies.

New Sequencing Technologies Reshape NIAID's Sequencing Centers; Five-Year Contracts Total $106M (GenomeWeb News)
New sequencing technologies will play an important role at the three Genomic Sequencing Centers for Infectious Diseases that in April were awarded five-year contracts totaling $106 million from the National Institute of Allergy and Infectious Diseases.


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