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Bioinformatics News 06/2009 (Page 3)

A new lead for autoimmune disease (EurekAlert!)
( Children's Hospital Boston ) A major challenge in treating autoimmune disorders has been suppressing inflammatory attacks on body tissues without generally suppressing immune function. Now, a drug from Chinese medicine shows potential for easing these disorders. In both mice and humans, it selectively inhibits development of Th17 cells, newly-recognized immune cells that were recently ...

Buffalo to host major international conference on biomedical ontology in July (EurekAlert!)
( University at Buffalo ) Whether and how medical personnel and their digital systems can talk to one another in a meaningful way is a subject pertinent to the health of patients about whom they "converse."

GeneLink Subsidiary GeneWize Hosts First Annual Science Summit Featuring Presentations and Appearances by World ... (Business Wire via Yahoo! Finance)
ORLANDO, Fla.----GeneLink, Inc. , "the Company," or "GeneLink", a leading consumer genomics biotech company, today reported that its wholly owned subsidiary, GeneWize Life Sciences, Inc. , held its first annual Affiliate Conference and "Science Summit" in Orlando on May 29-30 for over 250 Affiliates and their guests.

NHGRI Unveils Wide-Ranging Recommendations Regarding Sequencing Initiatives (GenomeWeb News)
NEW YORK (GenomeWeb News) – The arrival of next generation sequencing power and other new technologies is changing the landscape of genomics research and its applications in medicine and beyond, and the National Human Genome Research Institute is beginning to plot its course to adapt to these changes.

Lamorinda School notes for June 5 (Contra Costa Times)
School happenings from around Lamorinda

Lamorinda School notes for June 5 (Lamorinda Sun)
Lamorinda schools continue to perform well compared with other schools statewide, according to the latest rankings released by the State Department of Education last month.

J. Craig Venter is keynote speaker at National Science Foundation Conference (EurekAlert!)
( National Science Foundation ) J. Craig Venter -- regarded as one of the leading scientists of the 21st century for his numerous contributions to genomic research -- will be the keynote speaker at a meeting of National Science Foundation-funded researchers who represent efforts to enhance the quality and excellence of science, technology, engineering and mathematics education and research ...

A New Start For Autoimmune Disease (redOrbit)
A drug derived from the hydrangea root, used for centuries in traditional Chinese medicine, shows promise in treating autoimmune disorders, report researchers from the Program in Cellular and Molecular Medicine and the Immune Disease Institute at Children's Hospital Boston (PCMM/IDI), along with the Harvard School of Dental Medicine.

Australian researchers advance bowel cancer detection (News-Medical-Net)
Australian researchers have developed gene expression biomarkers which can accurately discriminate pre-cancerous and cancerous colorectal growths from non-cancerous controls.

Cancer vaccine efficacy enhanced using anti-diabetic drug Metformin (News-Medical-Net)
After a vaccination or an infection, the human immune system remembers to keep protecting against invaders it has already encountered, with the aid of specialized B-cells and T-cells. Immunological memory has long been the subject of intense study, but the underlying cellular mechanisms regulating the generation and persistence of long-lived memory T cells remain largely undefined. Now, ...

Matrix Genomics, Elizabeth Corder, PhD - Gene Variation in the LRRK2 Gene and High Risk for Parkinson's Disease (PRWeb via Yahoo! News)
Researchers at the National Institute on Aging, University College London, and Matrix Genomics, Inc. have identified a concise genetic signature found among a third of Parkinson's disease (PD) patients - but at very low frequency in the general population. The signature is found in the LRRK2 gene located on chromosome 12. The work was led by Elizabeth Corder, PhD, Scientific director at Matrix ...

Risks of sharing personal genetic information online need more study, Stanford bioethicists say (EurekAlert!)
( Stanford University Medical Center ) With just $399 and a bit of saliva in a cup, consumers can learn about their genetic risk for diseases from breast cancer to diabetes. Now, thanks to social networking sites set up by personal genomics companies, they can also share that information with family, friends and even strangers on the Internet.Bonding over a similar genetic background sounds ...

Risks of sharing personal genetic information online need more study, bioethicists say (PhysOrg)
With just $399 and a bit of saliva in a cup, consumers can learn about their genetic risk for diseases from breast cancer to diabetes. Now, thanks to social networking sites set up by personal genomics companies, they can also share that information with family, friends and even strangers on the Internet.

Researchers develop an intelligent chip which regulates diabetes (PhysOrg)
Scientists of the Electronic Technology group of the University of Seville (Spain), led by Professor José Manuel Quero, have completed the first phase of Mireia, a research project financed by the Plan Nacional del Ministerio de Ciencia e Innovación (National Plan of the Spanish Science and Innovation Ministry), whose aim is to develop an intelligent chip to regulate diabetes in any kind of ...

Applicants find some classes closed out (San Diego Union-Tribune)
When Megan Graham decided in March to go back to college, she eyed the master's program in economics at San Diego State University. The 26-year-old Pacific Beach resident took the required Graduate Record Examination, got some letters of recommendation and finished her application in time for the June 15 deadline.

Bio-partnering, IP & HR to feature as novel additions to Bangalore Bio '09 (PharmaBiz)
Bio-partnering, Intellectual Property and human resource development are the focus area of ninth edition of Bangalore Bio 2009. The event organized by the Department of Information Technology, Biotechnology and Science & Technology, Government of Karnataka, Vision Group on Biotechnology and MM Activ Sci-Tech Communications Co. will be held at Hotel Lalit Ashok, Bangalore from June 18 to June 20, ...

SwitchGear Genomics Assay-Ready 3'UTR Constructs Establish Validity in Studies That Identify Critical Functions of ... (Business Wire via Yahoo! Finance)
MENLO PARK, Calif.----SwitchGear Genomics Inc., a leading provider of products for studying the regulatory elements in the human genome, today announced the application of its UTR Reporter Collection™ product line in uncovering critical miRNA functions in several recent research studies.

Major International Conference On Biomedical Ontology To Be Hosted By Buffalo (Medical News Today)
Whether and how medical personnel and their digital systems can talk to one another in a meaningful way is a subject pertinent to the health of patients about whom they "converse." Internationally recognized ontologist Barry Smith, Ph.D.

Geography and history shape genetic differences in humans (EurekAlert!)
( Public Library of Science ) New research indicates that natural selection may shape the human genome much more slowly than previously thought. Other factors -- the movements of humans within and among continents, the expansions and contractions of populations, and the vagaries of genetic chance -- have heavily influenced the distribution of genetic variations in populations around the world. ...

In Print (GenomeWeb News)
Journal: American Journal of Medical Genetics . 2009 May;149A(5):914-8. Title: aCGH detects partial tetrasomy of 12p in blood from Pallister-Killian syndrome cases without invasive skin biopsy.

Covance Announces Monte Jarvis as Vice President of Global Data Management and Biostatistics for Periapproval Services (PR Newswire via Yahoo! Finance)
Data management, biostatistics expert adds more than 25 years of experience to support growing demand for periapproval services -

Geography, History Shape Genetic Human Differences (redOrbit)
New research indicates that natural selection may shape the human genome much more slowly than previously thought.

Risks Of Sharing Personal Genetic Information Online Needs More Study (redOrbit)
With just $399 and a bit of saliva in a cup, consumers can learn about their genetic risk for diseases from breast cancer to diabetes.

Laugh It Up, Just Like Your Ancestors Did (GenomeWeb News)
23andMe's ErinC has a post at the Spittoon about a paper in Current Biology from researchers at the University of Hannover in Germany who studied laughter in humans and apes . The findings indicate that "not only are the hoots, hollers and snorts of the great apes really laughter, but the evolutionary relationships between the sounds match up with the known evolutionary relationships between the ...

If You Can't Beat Them ... (GenomeWeb News)
Wall Street Journal reports that Carl Icahn won a seat on Biogen Idec's board of directors, with the results of a possible second seat still up in the air, according to the article.

Risks Of Sharing Personal Genetic Information Online Need More Study, Stanford Bioethicists Say (Medical News Today)
With just $399 and a bit of saliva in a cup, consumers can learn about their genetic risk for diseases from breast cancer to diabetes. Now, thanks to social networking sites set up by personal genomics companies, they can also share that information with family, friends and even strangers on the Internet. Bonding over a similar genetic background sounds relatively harmless.

Papers of Note (GenomeWeb News)
Wolfgang Huber applies statistical computing to analyze microarray, sequencing, and high-throughput automated microscopy data. One of his immediate goals it to use both array and sequencing data along with imaging to better understand the connections between genotype and phenotype.

Ethicists Call For Research on DTC Genomics Social Networking (GenomeWeb News)
NEW YORK (GenomeWeb News) – Ethicists are debating the research, social, and ethical implications of mixing social networking with direct-to-consumer genomics.

In Print (GenomeWeb News)
Blazewicz J, Bryja M, Figlerowicz M, Gawron P, Kasprzak M, Kirton E, Platt D, Przybytek J, Swiercz A, Szajkowski L. Whole genome assembly from 454 sequencing output via modified DNA graph concept . [ Comput Biol Chem . 2009 May 3. (e-pub ahead of print)]: Describes a new assembly algorithm for 454 sequencing data that "outperforms other assembly algorithms used in practice," according to the ...

Silence Therapeutics Cleared to Begin German Phase I Trial of Cancer Rx (GenomeWeb News)
Silence Therapeutics this week announced that German regulators have approved the company's application to begin a phase I study of its siRNA-based cancer drug Atu027.

CDC, NIH to Start Genomic Applications Network (GenomeWeb News)
NEW YORK (GenomeWeb News) – The US Centers for Disease Control and Prevention and the National Institutes of Health is developing a genomics network that will attempt to integrate genomic information into medicine and public health.

New Technology Combining Bruker's MALDI-TOF/TOF with Bio-Rad's SELDI Set to Launch (GenomeWeb News)
Bruker and Bio-Rad Laboratories are launching a new system linking Bruker's MALDI-TOF/TOF platform with Bio-Rad's SELDI technology that is expected to enable researchers to detect a class of proteins and peptides that other technologies have tripped over.

People in the News (GenomeWeb News)
Compugen said this week that Anat Cohen-Dayag and Martin Gerstel will serve as co-CEOs of the company. Cohen-Dayag started with the company in 2002, and she has served as VP for diagnostic biomarkers and drug targets.

Bioinformatics Software Firms Prep New Next-Gen Analysis Tools for Summer Rollout (GenomeWeb News)
Anticipating increased demand for improved sequence analysis tools amid the rise of next-generation sequencers, several bioinformatics companies are planning to launch new versions of their software over the next few months with new capabilities for analyzing data from these platforms.

Downloads and Upgrades (GenomeWeb News)
The Department of Energy Joint Genome Institute has released an "enhanced version" of Phytozome.net , a web portal on green plant comparative genomics that has biofuel, food, feed, and fiber research as its focus.

Waters' Synapt G2 opens new frontiers in scientific discovery (PharmaBiz)
Waters has launched the powerful next-generation, high performance, mass spectrometer, Synapt G2 System, taking qualitative and quantitative quadrupole time-of-flight mass spectrometry to new heights.

CLC bio releases new versions of Next Generation Sequencing solutions (PharmaBiz)
CLC bio announced the release of new versions of their premier solutions for analyzing and visualizing Next Generation Sequencing data, the desktop application CLC Genomics Workbench, version 3.5 and the award-winning enterprise platform CLC Genomics Server, version 1.5. With this release, CLC bio is making a major push into epigenomics by supporting chromatin immunoprecipitation sequencing ...

Cancer Vaccine Efficacy Enhanced Using Anti-Diabetic Drug Metformin (Medical News Today)
After a vaccination or an infection, the human immune system remembers to keep protecting against invaders it has already encountered, with the aid of specialized B-cells and T-cells. Immunological memory has long been the subject of intense study, but the underlying cellular mechanisms regulating the generation and persistence of long-lived memory T cells remain largely undefined.

A New Lead For Autoimmune Disease (Medical News Today)
A drug derived from the hydrangea root, used for centuries in traditional Chinese medicine, shows promise in treating autoimmune disorders, report researchers from the Program in Cellular and Molecular Medicine and the Immune Disease Institute at Children's Hospital Boston (PCMM/IDI), along with the Harvard School of Dental Medicine.

New Protein Center Opens (Medical News Today)
On the 4th June, the Faculty of Health Sciences at the University of Copenhagen will open the doors of its new research center, The Novo Nordisk Foundation Center for Protein Research. The Center is the result of a historic donation from the Novo Nordisk Foundation, which in 2007 gave the University 80 million euros for its establishment.

The Price of Knowledge (GenomeWeb News)
In the very early days of genetic testing, opponents argued that knowing about a gene-related susceptibility to a disease that couldn't be cured was far worse than ignorance.

Streaming Science: Keeping Tabs on Your Research (GenomeWeb News)
Over at his Bioinformatics Zen blog, Michael Barton writes about setting up streams -- think of them like RSS feeds from a news source -- that report his most recent research activity from Twitter.

Breast Cancer Gene Can Be Blocked By Blood Pressure Drug (Science Daily)
Researchers have identified a gene that is overexpressed in up to 20 percent of breast cancers and that could be blocked in the lab by a currently available blood pressure drug, according to a new study.

St. Joseph set to feel effects of jobs bill (St. Joseph News-Press)
Gov. Jay Nixon tours the state this week to sign into law a jobs bill with implications on two things there are no shortage of here — animal health companies and old houses.

Researchers at NCRC using bioinformatics (The Salisbury Post)
By Emily Ford [email protected] Scientific research under way at the N.C. Research Campus generates so much biological information that no sprea ...

UNCCÕs role at Research Campus expands (The Salisbury Post)
By Emily Ford [email protected] The University of North Carolina at Charlotte has two different but related roles at the N.C. Research Campus. I ...

Eighth International Conference On Bipolar Disorder To Be Held In Pittsburgh, June 25 To 27 (Medical News Today)
Nearly 1,000 researchers, clinicians and mental health advocates are expected to attend the Eighth International Conference on Bipolar Disorder, June 25 to 27, at the David L. Lawrence Convention Center in Pittsburgh. The event is held only once every two years and is the largest meeting of its kind solely devoted to bipolar disorder, a disease that affects almost six million Americans.

As PerkinElmer Merger Nears, Packard Plows Ahead with New Array Offerings (GenomeWeb News)
Despite its looming merger with PerkinElmer, Packard Biosciences has aggressively pushed to launch new products in the microarray sector this fall.

Seattle Startup Develops Regression Analysis Program for Large-scale Array Experiments (GenomeWeb News)
When microarray experiments involve hundreds of samples, powerful statistical approaches are going to be needed to analyze this mass of data.

Researchers Report on Latest Protein Chip Developments at Berlin Array Conference (GenomeWeb News)
Researchers using microarray technologies for protein analysis came together for a two-day meeting in Berlin two weeks ago to discuss the latest developments in this growing field.


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