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Bioinformatics News 05/2009 (Page 4)

Whole Genome Sequencing Approach For Mutation Discovery (Science Daily)
Scientists have developed a "whole-genome sequencing approach" to mapping mutations in fruit flies. The novel methodology promises to reduce the time and effort required to identify mutations of biological interest.

Stowers Researchers Develop Whole Genome Sequencing Approach For Mutation Discovery (Medical News Today)
The Stowers Institute's Hawley Lab and Molecular Biology Facility have developed a "whole-genome sequencing approach" to mapping mutations in fruit flies. The novel methodology promises to reduce the time and effort required to identify mutations of biological interest. The work was published in the May issue of the journal GENETICS.

LOV story (The Scientist)
Even nonphotosynthetic bacteria respond to light in surprising ways. Have scientists found a new ubiquitous signaling mechanism?

Personalized Medicine Advocates Urge New HHS Secretary to 'Strike the Right Balance' in Regulating Genetic Tests (GenomeWeb News)
More than 100 proponents of personalized medicine have issued a letter to the new Secretary of the Department of Health and Human Services Kathleen Sebelius asking her to "get personalized medicine right" by "creating and implementing a reasonable and responsible regulatory framework" for genetic tests and other advanced medical diagnostics.

In Bid to Grow Enrollment, PGP Issues Entrance Exam to Ensure Genetics Literacy of Participants (GenomeWeb News)
Aiming to increase enrollment in the Personal Genome Project from its current 10 participants to 100 by this summer, Harvard Medical School's Institutional Review Board will administer an entrance exam to ensure recruits come into the project with basic genetic literacy.

The Hindu Business Line : Ocimum Bio’s test to detect swine flu (The Hindu)
Hyderabad, May 6 As the swine flu fear continues to grip people and authorities screen visitors with flu-like symptoms from abroad, an Indian company has come up with a test to detect it fast.

Sequencing of Peptides in Second Dinosaur Puts Controversy About Findings to Rest … For Now (GenomeWeb News)
Researchers who last week published a proteomics study on an 80 million year old dinosaur are hoping they have silenced the critics who cast doubt on their earlier work on a Tyrannosaurus rex fossil.

CDC Working with Assay Developers on Swine Flu MDx Tests (GenomeWeb News)
NEW YORK (GenomeWeb News) – Officials from the US Centers for Disease Control and Prevention are working on getting molecular diagnostic assays cleared for use on new platforms with new chemistries for identifying the influenza A H1N1 virus, according to speakers during an "influenza town hall meeting" organized by the Association of Public Health Laboratories.

DNA LandMarks to Support USDA Chicken Genomics Program (GenomeWeb News)
NEW YORK (GenomeWeb News) – The Canadian genomics and bioinformatics company DNA LandMarks will provide support services for a US Department of Agriculture-led program to study the chicken genome for potential improvements for breeding, the company said today.

Response Biomedical's Q1 Revenues Rise; Proposes Unit Offering (GenomeWeb News)
NEW YORK (GenomeWeb News) – Response Biomedical today reported that its first-quarter revenues rose 131 percent, while its net loss fell around 50 percent.

Proteomics International Develops Process to ID Venom Peptides for Drug Development (GenomeWeb News)
Spiders, snakes, and cen tipedes may be the stuff nightmares are made of, but for one Australian firm they may form the foundation for its future.

CombiMatrix Corporation Reports First Quarter 2009 Financial Results (GlobeNewswire via Yahoo! Finance)
MUKILTEO, Wash., May 6, 2009 -- CombiMatrix Corporation today reported financial results for the three months ended March 31, 2009. Key highlights for the first quarter and through the date of this release include:

Celera Revenues Up as Loss Declines in Q1 (GenomeWeb News)
NEW YORK (GenomeWeb News) – Celera reported after the close of the market on Wednesday that its first-quarters revenues increased 16 percent, while the firm cut its net loss significantly on lower charges year over year.

CombiMatrix's Sales Drop in First Quarter (GenomeWeb News)
NEW YORK (GenomeWeb News) – CombiMatrix reported after the close of the market on Wednesday that its first-quarter revenues tumbled 23 percent year over year on weak government contracts and product sales.

As RNAi Rx Space Matures, More Shops Focus on Developing Delivery Tech In House (GenomeWeb News)
With delivery remaining the key problem facing the successful development of RNAi therapeutics, an increasing number of players in the field are looking within their own labs for solutions, often using delivery technologies as the foundation upon which to build their businesses.

Driving On Mushroom Fumes (Forbes)
Gary Strobel's latest find: a fungus that produces diesel.

That's Why You Should Always Be Nice to the Receptionist (GenomeWeb News)
Over at Bitesize Bio, Suzanne Kennedy blogs about networking your way to a better career, and specifically how she uses two sites: LinkedIn and Labroots. "Networking is critical because biotech and bioscience in general are very small worlds," she writes.

Memorial computer science lectures begin (Scoop.co.nz)
The inaugural Peter Gibbons Memorial Lecture Series, sharing developments in computer science research with the wider public, will begin at The University of Auckland on Wednesday 13 May.

Sirius Genomics Announces New Collaboration with Vanderbilt University (PR Newswire via Yahoo! Finance)
Sirius Genomics, a developer of pharmacogenomic diagnostics, announced today that it has signed a collaborative agreement with Vanderbilt University to study patients enrolled in Vanderbilt's Validating Acute Lung Injury biomarkers for Diagnosis study.

Foundation Gives SRI $100K Grant (The Harrisonburg Daily News-Record)
HARRISONBURG - SRI International's Center for Advanced Drug Research in Rockingham County has received a $100,000 grant for tuberculosis research.

Sirius Genomics Announces New Collaboration with Vanderbilt University (PR Newswire via Yahoo! Finance)
Sirius Genomics, a developer of pharmacogenomic diagnostics, announced

Generalized anxiety disorder (Mayo Clinic)
Dr. Daniel Hall-Flavin, board certified in general psychiatry and addiction psychiatry, is a St. Louis native looking to the Internet as a way to help people improve their health and be more active participants in their own health care by learning from Mayo Clinic's experts.

CombiMatrix to Present Comprehensive Cancer Array Data At DxRx Summit: Nucleic Acid Diagnostics & Therapeutics (GlobeNewswire via Yahoo! Finance)
MUKILTEO, Wash., May 7, 2009 -- CombiMatrix Corporation today announced Dr. Amit Kumar, President and CEO, will present at the DxRx Summit: Nucleic Acid Diagnostics & Therapeutics in Boston, Massachusetts on May 13th at 11:30 am EDT.

La Jolla Institute Announces 2.0 Launch Of Major Database To AID Vaccine Development Worldwide (Medical News Today)
Key improvements in a major infectious disease database that will aid vaccine development worldwide were unveiled with the 2.0 launch of the National Institutes of Health-sponsored Immune Epitope Database and Analysis Resource (IEDB). The 2.

$100,000 Grand Challenges Explorations Grant Received By SRI International To Combat Antibiotic Resistance In ... (Medical News Today)
SRI International has announced that it has received a US$100,000 Grand Challenges Explorations grant from the Bill & Melinda Gates Foundation. The grant will support an innovative global health research project conducted by Krishna Kodukula, Ph.D., executive director of SRI International's Center for Advanced Drug Research (CADRE) in Shenandoah Valley, Virginia and Amit Galande, Ph.D.

QIAGEN to Present At the Bank of America and Merrill Lynch 2009 Healthcare Conference (GlobeNewswire via Yahoo! Finance)
VENLO, The Netherlands, May 7, 2009 -- QIAGEN N.V. today announced that it will present at the Bank of America and Merrill Lynch 2009 Healthcare Conference at 10:00 a.m. ET on Wednesday, May 13, 2009.

Signature Genomic Laboratories Detects Chromosome Abnormalities in Individuals with Pallister-Killian Syndrome without ... (Business Wire via Yahoo! Finance)
SPOKANE, Wash.----Geneticists at Signature Genomic Laboratories have demonstrated that microarray-based genetic testing can identify a rare genetic disorder using DNA from blood rather than the more-invasive skin biopsy routinely used for testing.

But This Way You Don't Get to Enjoy the Wine and Cheese (GenomeWeb News)
If you couldn't make it to Cold Spring Harbor this year for the Biology of Genomes meeting, don't miss Daniel MacArthur's blogtastic coverage. He's been posting highlights of the sessions to his Genetic Future blog, including the opening talks on cancer genomics from Mike Stratton and Elaine Mardis.

Now We Know Why They Need So Many Reviewers (GenomeWeb News)
If you'd rather believe the NIH review process is a smooth and efficient one, you'd better skip to the next post. At his Genomics, Evolution, and Pseudoscience blog, Steven Salzberg airs his frustration with one small part of the study section process -- namely, password protection for proposals . Salzberg receives grant applications for review on a CD, and each proposal is password-protected.

Time to Wade Through Some Lab Notebooks (GenomeWeb News)
Science Insider reports on the " long-awaited review of the scientific evidence relating to the investigation of the 2001 anthrax letter attacks" now that FBI has agreed to let the National Academy of Sciences study the "scientific techniques used ... in solving the case."

Evotec Buys Zebrafish Screening Business of Summit (GenomeWeb News)
NEW YORK (GenomeWeb News) – German firm Evotec said today that it will buy the zebrafish screening operations of UK company Summit for around £500,000 ($754,000).

Monogram Biosciences' Q1 Revenues Decline 4 Percent (GenomeWeb News)
NEW YORK (GenomeWeb News) – Monogram Biosciences reported after the close of the market on Wednesday that its first-quarter revenues fell 4 percent on lower product revenue and its net loss surged on a convertible debt valuation adjustment.

Movers & Shakers (GenomeWeb News)
Harvey's retirement took effect earlier this week. He will remain a director.

This Week in Nature (GenomeWeb News)
Published in Nature 's early online edition, researchers at Memorial Sloan-Kettering Cancer Center led by Joan Massagué have found genes that control breast cancer metastasis to the brain . The BBC reports on it here . Performing gene expression analysis on cells that preferentially infiltrate the brain from patients with advanced disease, they found the cyclooxygenase COX2, the EGFR ligand ...

Illumina introduces breakthrough software advancements with Genome AnalyzerIIx sequencing system (SeedQuest)
Illumina, Inc. (NASDAQ:ILMN) today announced breakthrough software advancements for its sequencing platform that enable real time analysis and provide a significant reduction in computing infrastructure requirements.

07.05.2009 - DJ HUGIN NEWS/TheraCode GmbH acquires JPT Peptide Technologies GmbH (4investors)
Berlin/Germany, May 7, 2009. - TheraCode GmbH a wholly owned subsidiary of BioNTech AG (Mainz, Germany), a biotech company developing novel personalized immunotherapy approaches today announced the acquisition of all shares of JPT Peptide Technologies GmbH (JPT) from Jerini AG (Berlin, Germany).

Broad Institute Uses Helicos Sequencing Technology to Analyze Replication Origins in Yeast Genomes (GenomeWeb News)
COLD SPRING HARBOR, NY — Researchers at the Broad Institute, in collaboration with Helicos BioSciences, have used the company's sequencing technology to identify origins of replication in the genomes of several fission yeast species, thus doubling the number of eukaryotes for which such an analysis has been performed on a genome-wide level.

FDA Clears Tekmira to Begin Phase I Study of siRNA-Based Cholesterol Drug (GenomeWeb News)
The US Food and Drug Administration has approved Tekmira Pharamceuticals' investigational new drug application for its siRNA-based hypercholesterolemia drug ApoB SNALP, the company said today.

Sirius Collaborates with Vanderbilt on PGx Test (GenomeWeb News)
NEW YORK (GenomeWeb News) – Diagnostics developer Sirius Genomics will collaborate with Vanderbilt University to study patients in a biomarker study for a drug aimed at treating severe sepsis, the company said today.

Currency Translation Drags Orchid's Revenues Down 3 Percent (GenomeWeb News)
NEW YORK (GenomeWeb News) – Orchid Cellmark today reported that its first-quarter revenues were down 3 percent, due to the adverse impact of foreign currency translation.

New Storage Options Ease Some Life Science IT Woes, Bio-IT World Panelists Say (GenomeWeb News)
Challenges related to storing and managing massive amounts of -omics data have eased considerably in recent years, according to participants and speakers at last week's Bio-IT World Conference and Expo in Boston.

Case Western Reserve med school wins $3 million-plus grant (Crain's Cleveland Business)
The federal money will be used to study how past or present drug abuse and Hepatitis C co-infection affect the progression of HIV and treatments.

Ontario, Canada Investing in Science to Strengthen Economy (Business Wire via Yahoo! Finance)
TORONTO----Ontario is launching a new fund to attract and retain world-leading genomics researchers in the province.

Obama's 2010 Budget Proposes $30.8B for NIH (GenomeWeb News)
NEW YORK (GenomeWeb News) – In a $3.6 trillion budget delivered to Congress today, the Obama Administration has requested increased funding for all of the major agencies that conduct research, including a 1.5 percent increase for the National Institutes of Health, for Fiscal Year 2010.

Nanosphere's Q1 Revenues Fall More than 50 Percent (GenomeWeb News)
NEW YORK (GenomeWeb News) – Nanosphere today posted a 56 percent slide in first-quarter revenues that it attributed to delays in regulatory clearance for its new products.

Luminex Revenues Up 11 Percent in Q1 (GenomeWeb News)
NEW YORK (GenomeWeb News) – Luminex reported after the close of the market on Thursday that its first-quarter revenues rose 11 percent, while its net loss rose on a litigation settlement.

Millipore's Q1 Revenues Increase 3 Percent; Profit Rises Sharply (GenomeWeb News)
NEW YORK (GenomeWeb News) – Millipore reported after the close of the market on Thursday that its first-quarter revenues rose 3 percent and its profit rose 71 percent as it kept its spending relatively static with last year.

AnaSpec Launches Z-Fish Antibodies (Business Wire via Yahoo! Finance)
SAN JOSE, Calif.----Zebrafish as an experimental model has gained widespread use since the pioneering days of Dr. George Streisinger. In the year 1980, there were 18 publications, 72 in 1990, 540 in 2000 and 1159 in 2008.1 To date, there are more than 13,200 publications.2 In order to address the growing needs of the research community for zebrafish specific antibodies, peptides and other ...

Teams of Scientists in Singapore and Hungary Collaborate to Discover Cures and Therapies to Advance Healthcare Delivery (Japan Corporate News)
Singapore, Apr 23, 2009 - (ACN Newswire) - Singapore's Agency for Science, Technology and Research (A*STAR) and Hungarys National Office for Research and Technology (NKTH) awarded grants to four new research projects in cancer, bio-imaging for stem cell therapy, stroke rehabilitation and drug delivery at the 2nd Singapore-Hungary Joint Symposium held in Singapore today.

Case Western Reserve to receive more than $3M from NIDA (EurekAlert!)
( Case Western Reserve University ) The Center for Proteomics and Bioinformatics and the Case Center for AIDS Research at Case Western Reserve University School of Medicine have a received a $989,108 grant from the National Institute of Drug Abuse at the National Institute of Health, with the ability to receive a total of $3,007,946 by 2011.


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