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Bioinformatics News Apr 2009

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Life Technologies Assay Confirmed as Authorized Swine Flu Panel for US Testing
NEW YORK (GenomeWeb News) – Following on yesterday's report that the US Food and Drug Administration has authorized the emergency use of a molecular diagnostic assay to identify cases of swine flu in the current outbreak, GenomeWeb Daily News has confirmed that Life Technologies is the manufacturer of the sole molecular-based test cited by FDA under the Emergency Use Authorization issued on ... (Wed, 29 Apr 2009 19:47:53 GMT)

People Transfer
Alfred Gilman has been named chief scientific officer of the Cancer Prevention and Research Institution of Texas. (Wed, 29 Apr 2009 19:48:03 GMT)

Histone modifications at human enhancers reflect global cell-type-specific gene expression
The human body is composed of diverse cell types with distinct functions. Although it is known that lineage specification depends on cell-specific gene expression, which in turn is driven by promoters, enhancers, insulators and other cis-regulatory DNA sequences for each gene, the relative roles of these regulatory elements in this process are not clear. We have previously developed a ... (Wed, 29 Apr 2009 20:44:34 GMT)

Expert Available to Talk About Contingency Planning for Flu Outbreaks/Pandemics
Researchers at the Virginia Bioinformatics Institute at Virginia Tech are using high-performance computer simulations to show how diseases like flu spread through large populations. They want to provide policymakers, decision-makers, and public health experts with a way to test health interventions that would help to put the brakes on the spread of a deadly influenza outbreak. (Wed, 29 Apr 2009 21:01:07 GMT)

Symposium on the prevention of weight (re-)gain
Under the title 'Prevention of weight (re-)gain - diet, genetics, behaviour, screening and novel food ingredients', DIOGENES researchers and external experts will discuss the following topics: - the relative efficacy of different diets in preventing weight gain, regain and co-morbidities; - genomics-based predictors of weight variation, and biomarkers of nutritional status; - epidemiological ... (Wed, 29 Apr 2009 22:30:36 GMT)

Sequenom's Q1 Revenues Fall 18 Percent, Net Loss Doubles
NEW YORK (GenomeWeb News) – Sequenom reported after the close of the market on Wednesday that its first-quarter revenues declined 18 percent year over year, while its net loss more than doubled on higher expenses. (Wed, 29 Apr 2009 22:32:53 GMT)

Video: Turning Hope Into Reality - Genomics Research at the VA
VA's Office of Research and Development is at the forefront of developing safer, more effective treatments based on new knowledge about the role of genes in health and disease. VA is superbly fitted to study genomics--the use of patients' individual genetic profiles to customize care--because of its genomics laboratory; large and diverse patient population; world-class investigators; an ... (Thu, 30 Apr 2009 00:42:00 GMT)

In Print
Bao H, Guo H, Wang J, Zhou R, Lu X, Shi S. MapView: visualization of short reads alignment on a desktop computer . [ Bioinformatics . 2009 Apr 15. (e-pub ahead of print)]: Describes a visual analytics tool called MapView that represents large-scale short-read alignment data and genetic variation analysis. (Thu, 30 Apr 2009 04:17:53 GMT)

Research and Markets: Essential Pharmaceutical and Environmental Analysis of Nano Chromatography and Capillary ...
DUBLIN----Research and Markets has announced the addition of John Wiley and Sons Ltd's new report "Nano Chromatography and Capillary Electrophoresis: Pharmaceutical and Environmental Analyses" to their offering. (Thu, 30 Apr 2009 05:00:00 GMT)

Veredus Laboratories develop test—kit to detect Swine Flu
SINGAPORE: Singapore life sciences company Veredus Laboratories said on Thursday it has developed a portable test—kit called Vereflu, which is able to identify the swine flu virus in just two hours. (Thu, 30 Apr 2009 05:16:55 GMT)

A systems biology map of iron metabolism
Scientists at the Wake Forest University School of Medicine, the University of Manchester in the United Kingdom, and the Virginia Bioinformatics Institute at Virginia Tech have taken the first steps toward constructing a systems biology map of iron metabolism. (Thu, 30 Apr 2009 09:31:44 GMT)

News From The Journal Of The National Cancer Institute, April 28 2009
Designing a Randomized Controlled Trial for Physical Activity, Weight Control, and Breast Cancer Risk Researchers describe the rationale and a possible design for randomized controlled trials that test the impact of physical activity and weight control on breast cancer risk. (Thu, 30 Apr 2009 10:18:43 GMT)

Veredus Laboratories develop test—kit to detect swine flu
SINGAPORE: Singapore life sciences company Veredus Laboratories said on Thursday it has developed a portable test—kit called Vereflu, which is able to identify the swine flu virus in just two hours. (Thu, 30 Apr 2009 10:23:02 GMT)

Revealing The Protein Effects Of Hormone Replacement Therapy
An in-depth proteomic analysis of the sera of 50 participants from the Women's Health Initiative (WHI) hormone replacement therapy trial provides some explanations for the trial's clinical results. The study, published in Biomed Central's open access journal Genome Medicine, shows that estrogen upregulates proteins involved in several major body processes. Samir Hanash, M.D., Ph.D. (Thu, 30 Apr 2009 11:17:12 GMT)

Clinical Genomics Continues Progress In Developing Biomarker Portfolio For Colorectal Cancer Testing
Clinical Genomics Pty Ltd, an Australian biotechnology company, announced that Quest Diagnostics Incorporated, the world's leading provider of diagnostic testing, information and services, has agreed to provide milestone payments over the next two years to Clinical Genomics to further develop its portfolio of gene-based biomarkers associated with early onset of colorectal cancer. (Thu, 30 Apr 2009 11:19:23 GMT)

Taking the strain
Researchers in the UK and North America tell The Engineer about the technologies they are developing to help stop the spread of deadly swine flu. (Thu, 30 Apr 2009 11:37:36 GMT)

Rosetta Genomics Announces Closing of License and Collaboration Agreement
REHOVOT, Israel----Rosetta Genomics Ltd. , an innovative molecular diagnostic company, today announced the closing of its previously announced license and collaboration transaction with Prometheus Laboratories Inc., pursuant to which Rosetta has granted Prometheus U.S. rights to three recently introduced, microRNA-based cancer diagnostic tests: miRview™ mets, miRview™ squamous and miRview™ meso. (Thu, 30 Apr 2009 12:00:00 GMT)

Abraxis BioScience Names Lonnie Moulder President and Chief Executive Officer; Soon-Shiong Remains Executive Chairman
LOS ANGELES----Abraxis BioScience, Inc. , a fully integrated biotechnology company, today announced that Leon O. Moulder, Jr., has been appointed Vice Chairman, President and Chief Executive Officer. (Thu, 30 Apr 2009 12:05:00 GMT)

Paterson talks up Western New York
Gov. David A. Paterson was in Buffalo Wednesday to convince trade representatives from around the world that Western New York is a prime investment opportunity. (Thu, 30 Apr 2009 12:05:59 GMT)

Arrayit to Mass Produce Rapid H1N1 Swine Flu Test Chip
SUNNYVALE, California, April 30 /PRNewswire/ -- Arrayit Corporation (OTC Bulletin Board: ARYC), a leading manufacturer of products and services for disease prevention, treatment and cure, announced today that it is developing a microarray-based diagnostic test to detect the H1N1 swine flu virus. (Thu, 30 Apr 2009 12:10:46 GMT)

CLC bio's Enterprise Platform Wins Award At Bio-IT World Expo In Boston
BOSTON----CLC bio's enterprise platform for Next Generation Sequencing data analysis, CLC Genomics Server, has just been awarded the "Best of Show" prize at the Bio-IT World Conference & Expo 2009 - an award judged by a team of Bio-IT World magazine editors and leading industry experts. (Thu, 30 Apr 2009 14:06:00 GMT)

Rosetta, Prometheus Close Deal for miRNA Dx Market Rights
Rosetta Genomics this week announced that its previously announced license and collaboration deal with Prometheus Laboratories has closed. (Thu, 30 Apr 2009 14:33:56 GMT)

More on IVDs and Swine Flu
CombiMatrix Corp. announced that it has updated its Influenza-Detection Microarray to include sequence information of the latest strain of swine flu. The previous version of the Influenza-Detection Microarray already detected many strains of swine flu as well as the pathogenic bird flu. (Thu, 30 Apr 2009 14:38:46 GMT)

Bruker Q1 Revs Shrink 3.3 Percent, Profits Rise to $8.6M
Bruker this week reported revenues slid 3.3 percent to $230.5 million compared to $238.3 million a year ago. (Thu, 30 Apr 2009 15:33:05 GMT)

INFOTHERM® now also leads to the most suitable substances via material classes
At ACHEMA, FIZ CHEMIE Berlin will present the INFOTHERM®database, which has been expanded with numerous search functions, and release more than 100,000 additional tables / The introduction of the IUPAC standard ThermoML results in faster access to technical knowledge / Presentations of new INFOTHERM®features May 12 & 13 at 11:30 am and 2:30 pm at the shared exhibition space for FIZ CHEMIE and ... (Thu, 30 Apr 2009 15:35:29 GMT)

This Week in Nature
Two GWAS studies of autism spectrum disorders appearing in this week's early online edition of Nature have gotten a lot of mainstream press . In the first, comprising over 10,000 subjects of European ancestry, CHOP's Hakon Hakonarson's team found six SNPs on chromosome 5p14.1 between cadherin 10 and cadherin 9 to be strongly associated with ASDs. (Thu, 30 Apr 2009 16:02:53 GMT)

Cutbacks at ACS
The American Chemical Society is cutting back, laying off 56 employees or three percent of its workforce . Most of the layoffs, 40, are in the society's Publications Division with nine of the Chemical and Engineering News staff and 10 of C&EN' s Journal News & Community Department being let go. (Thu, 30 Apr 2009 16:03:04 GMT)

A Virologist's Look at the Swine Flu Genome
Science Insider has an interview with the head of the CDC's molecular virology and vaccines branch, Ruben Donis. In the Q&A Donis talks about what's known about the swine flu genome -- it's 14 kb and is "almost equidistant to swine viruses from the United States and Eurasia." (Thu, 30 Apr 2009 16:17:53 GMT)

Don't Wait Your Turn
One of DrugMonkey's readers relayed a bit of a situation. The reader is working on an R01 but a colleague who sits on a study section told the reader to " definitely wait two years so [the reader] can get things rolling before applying." (Thu, 30 Apr 2009 16:18:03 GMT)

Open Access on the Airwaves
Jonathan Eisen points to a story on Marketplace that discusses open-access publishing. (The text is here and audio here .) In it, Janet Babin starts out by speaking with Josh Summer who, after being diagnosed with a chordoma, set out to find out more about his disease. (Thu, 30 Apr 2009 16:18:13 GMT)

Swine flu case suspected
One student test positive for Type A influenza, but further testing required (Thu, 30 Apr 2009 16:39:25 GMT)

QIAGEN Tests Clinically Verified for the Monitoring of Swine Flu
KJ VENLO, GERMANY--(Marketwire - April 30, 2009) - German Bernhard Nocht Institute and Spanish Reference Laboratory Unequivocally Detect Infections with the H1N1 Strain Using the artus Influenza Test Venlo, The Netherlands - April 30, 2009 - Analyses performed by the German Bernhard Nocht Institute for Tropical Medicine have proven that the influenza A / H1N1 virus can be unequivocally detected ... (Thu, 30 Apr 2009 17:27:43 GMT)

Study validates means to measure possible leukemia marker
( Ohio State University Medical Center ) Ohio State University cancer researchers show that a technology called liquid chromatography-mass spectroscopy can reliably and reproducibly measure variations in the composition of histone proteins in chronic lymphocytic leukemia (CLL) cells compared with their healthy counterparts, immune cells called B lymphocytes. These variations are a promising ... (Thu, 30 Apr 2009 17:46:14 GMT)

DJ HUGIN NEWS/QIAGEN Tests Clinically Verified for the Monitoring of Swine Flu
German Bernhard Nocht Institute and Spanish Reference Laboratory Unequivocally Detect Infections with the H1N1 Strain Using the artus Influenza Test Venlo, The Netherlands - April 30, 2009 - Analyses performed by the German Bernhard Nocht Institute for Tropical Medicine have proven that the influenza A / H1N1 virus can be unequivocally detected using a screening test developed by QIAGEN (NASDAQ: ... (Thu, 30 Apr 2009 17:54:36 GMT)

Study validates means to measure possible leukemia marker
A study led by cancer researchers at The Ohio State University has validated a method for reliably measuring variations in certain proteins that may make good biomarkers in chronic leukemia patients. (Thu, 30 Apr 2009 18:00:50 GMT)

Best of Show Awards Winners Named at Bio-IT World Conference & Expo
Products from Aspera, CLC Bio, Maxis IT and Rescentris recognized for their innovation across the life sciences research, discovery, and clinical trials process. (PRWeb Apr 30, 2009) Read the full story at http://www.prweb.com/releases/20 (Thu, 30 Apr 2009 18:11:57 GMT)

QIAGEN Tests Clinically Verified for the Monitoring of Swine Flu
German Bernhard Nocht Institute and Spanish Reference Laboratory Unequivocally Detect Infections With the H1N1 Strain Using the artus Influenza Test (Thu, 30 Apr 2009 18:13:47 GMT)

30.04.2009 - DJ HUGIN NEWS/QIAGEN Tests Clinically Verified for the Monitoring of Swine Flu
Venlo, The Netherlands - April 30, 2009 - Analyses performed by the German Bernhard Nocht Institute for Tropical Medicine have proven that the influenza A / H1N1 virus can be unequivocally detected using a screening test developed by QIAGEN (NASDAQ: QGEN; Frankfurt Prime Standard: QIA). The company's artus Influenza LC RT PCR Kit was successfully used to screen a female patient who had come down ... (Thu, 30 Apr 2009 18:14:30 GMT)

National Institute of Statistical Sciences Hires Six New Postdoctoral Fellows—Most in History
The National Institute of Statistical Sciences (NISS), a research institute created by the national statistical sciences community, has appointed six new postdoctoral fellows. The fellows will participate in several new research programs at NISS. “Our research has expanded into several additional areas this year. We are happy to be able to hire some of the best and brightest people coming… (Thu, 30 Apr 2009 19:00:33 GMT)

Med BioGene Loss Shrinks as It Prepares Lung Test Launch
NEW YORK (GenomeWeb News) – Med BioGene said yesterday that its fiscal-year 2008 net loss declined slightly to C$2.3 million (US$1.9 million), or C$.07 per share, from C$2.4 million, or C$.09 per share. (Thu, 30 Apr 2009 19:02:55 GMT)

Team Uses Mass Spec to Sequence 80 Million Years Old Dino Peptides
NEW YORK (GenomeWeb News) – In a study appearing online today in Science , researchers from the US and UK provided mass spectrometry and other evidence suggesting dinosaur soft tissue and protein can survive up to 80 million years. (Thu, 30 Apr 2009 19:03:05 GMT)

Chasing Acquity, Agilent Launches 1290 UHPLC
Agilent Technologies this week launched the 1290 Infinity Liquid Chromatography System, which it said delivers the industry's largest analytical power range. (Thu, 30 Apr 2009 19:32:53 GMT)

ILW.COM - immigration news: 2009 Revised Exchange Visitor Skills List; Notice
[Federal Register: April 30, 2009 (Volume 74, Number 82)] [Notices] [Page 20107-20131] From the Federal Register Online via GPO Access [wais.access.gpo.gov] [DOCID:fr30ap09-157] [[Page 20107]] ----------------------------------------------------------------------- Part II Department of State ----------------------------------------------------------------------- 2009 Revised Exchange Visitor ... (Thu, 30 Apr 2009 20:09:36 GMT)

PerkinElmer's Q1 Revenues Down 6 Percent, Flat Organically
NEW YORK (GenomeWeb News) – PerkinElmer today reported after the close of the market that its first-quarter revenues declined 6 percent and were flat year over year on an organic basis. (Thu, 30 Apr 2009 20:47:55 GMT)

Gen-Probe's Q1 Product sales Rise 11 Percent
NEW YORK (GenomeWeb News) – Gen-Probe reported after the close of the market on Thursday that its overall revenues declined around 5 percent, but its product sales increased 11 percent year over year. (Thu, 30 Apr 2009 20:48:06 GMT)

Genome Research publishes special issue: Genomics and Darwinism
( Cold Spring Harbor Laboratory ) The May 2009 issue of Genome Research is a special issue celebrating the 200th anniversary of Charles Darwin's birth, and the 150th anniversary of the publication of "On the Origin of Species". Published online today, the issue features a collection of perspective reviews and primary research in comparative genomics, genome evolution, and population genomics. (Thu, 30 Apr 2009 21:13:17 GMT)

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