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India emerges as best option for contract manufacturing: Global Pharmatech chief
Contract manufacturing is one of the best options for the global pharma companies to look forward to in the wake of global recession. (Sat, 25 Apr 2009 02:48:35 GMT)
Bio-Rad Labs ties up with CCMB for research in proteomics
Bio-Rad Laboratories has tied up with CCMB, Hyderabad to set up a programme between the scientists on both sides on specific areas under the proteomics umbrella. (Sat, 25 Apr 2009 02:48:56 GMT)
Google Founder Larry Page Has Impregnated Model-Ph.D. Wife
Larry Page, the dorkier half of Google's founding duo, has mastered at least one basic human function: His wife, former model and Stanford bioinformatics Ph.D. Lucy Southworth, is pregnant. Took him... (Sat, 25 Apr 2009 04:13:53 GMT)
The biological basis for the 8-hour work-shift
Washington, April 24: Your usual nine to five office shift has a biological reason behind it, and now scientists have found that some genes in the body are switched on once every 12 or 8 hours, which in turn keeps us actively involved in the work, according to a new study. (Sat, 25 Apr 2009 05:04:34 GMT)
Biotechnology Company Provided Advance Warning of Mexican H1N1 "Swine Flu" Virus Outbreak
Replikins, Ltd. published a FluForecast® warning in April 7th, 2008, a year before the recent Mexico and California H1N1 cases. The company was able to state the likelihood of H1N1 outbreaks based on its patented Replikin Count™ genomics technology, which examines specific regions in virus genes which have been linked with past epidemics. (Sat, 25 Apr 2009 07:01:00 GMT)
Biotechnology Company Provided Advance Warning of Mexican H1N1 "Swine Flu" Virus Outbreak
Replikins, Ltd. published a FluForecast® warning in April 7th, 2008, a year before the recent Mexico and California H1N1 cases. The company was able to state the likelihood of H1N1 outbreaks based on its patented Replikin Count™ genomics technology, which examines specific regions in virus genes which have been linked with past epidemics.The April 2008 announcement, attached below as published ... (Sat, 25 Apr 2009 07:18:47 GMT)
NSF Awards Millions for Cloud Computing Research
CluE Awards promote academic use of cluster computing resources on IBM/Google cloud (Sat, 25 Apr 2009 08:34:44 GMT)
Thomson Reuters announces India Research Front Awards 2009
Thomson Reuters' Healthcare and Science business has announced the "Thomson Reuters Research Excellence - India Research Front Awards 2009." India's leading eight scientists were honoured for their research and influential contribution to global R&D on four research fronts. (Sat, 25 Apr 2009 09:18:26 GMT)
X PRIZE Foundation And Knome Spotlight DNA Day With Historic Charity Auction Of Whole Genome Sequence
To spotlight National DNA Day, which will be celebrated on April 25, The X PRIZE Foundation, an educational nonprofit prize institute dedicated to fostering radical breakthroughs for the benefit of humanity, and Knome, Inc., a leading personal genomics company, today announced a first of its kind charity auction. (Sat, 25 Apr 2009 10:05:32 GMT)
NFGC Conducts Multi-Institutional Research Project In Ovarian Cancer
The National Functional Genomics Center, funded through an assistance agreement that is awarded and administered by the U.S. Army Medical Research & Materiel Command (USAMRMC) and the Telemedicine & Advanced Technology Research Center (TATRC), will be conducting a multi-institutional collaborative project in ovarian cancer. (Sat, 25 Apr 2009 11:03:42 GMT)
Genotyping Tech Guide
With each passing technical guide on the matter, it seems that genotyping is becoming more and more commonplace — you hear about so many genotyping companies such that it seems as if everyone is getting into genotyping. Those of you in the trenches know that it's not as easy as it sounds. (Sat, 25 Apr 2009 12:47:53 GMT)
Scientists crack the cow code
Researchers have created the first genetic blueprint of domestic cattle, a map they say may lead to tastier beef, better milk and perhaps new insights into human health. (Sat, 25 Apr 2009 16:58:52 GMT)
We Like to Call It DNA Day
Go to the home page of Wikipedia, the online, collaborative encyclopedia that anyone can edit , and you will see that today’s featured article is about, yep, DNA! Congratulations, DNA, you’ve officially arrived. (Sat, 25 Apr 2009 18:17:53 GMT)
Finally, An Instruction Manual (Sort Of)
The Genetic Genealogist Blaine Bettinger has written an e-book on how to interpret DNA testing results. The 28-page book takes the reader through four chapters covering what is and isn't genetic genealogy, how to interpret Y-DNA and mtDNA results, and the field of genetic genealogy in general. (Sat, 25 Apr 2009 18:18:03 GMT)
Neanderthals Are Everywhere
Svante Pääbo is back. In the advanced online section of Nature , he and his collaborators report that the mitochondrial DNA from hominid remains found in Uzbekistan and southern Siberia are similar to the variations seen in European Neanderthal mtDNA, indicating that Neanderthals' range extended about 2,000 km further east than previously thought. (Sat, 25 Apr 2009 18:18:13 GMT)
Now They Just Have to Upgrade Their Voting Machines
The Florida Board of Education passed new science standards on a 4-3 vote , writes Joshua Rosenau at Thoughts From Kansas. (Sat, 25 Apr 2009 18:18:23 GMT)
Prince William High Schooler Will Spend Summer Vacation Researching Alzheimer's
Until recently, Ashley Groth, 16, a junior at Brentsville District High School, thought she was going to spend her summer trekking across the country visiting colleges and playing video games with friends. (Sun, 26 Apr 2009 04:00:00 GMT)
Third Wave, Digene, Chiron, and Bayer, Fisher Biosciences and U of Michigan, Tm Bioscience and ARUP Laboratories, UC ...
Third Wave Technologies said this week that it has filed two patent suits in federal court in Madison, Wis., related to its diagnostic tests for human papilloma virus and hepatitis C virus. (Sun, 26 Apr 2009 18:17:53 GMT)
An Extra Layer
In Illinois, state lawmakers outlawed employers from discriminating against employees based on genetic test results, causing Hsien-Hsien Lei to wonder why US states would pass their own law now that the federal Genetic Information Non-discrimination Act has been approved. (Sun, 26 Apr 2009 18:18:03 GMT)
As Long As They Don't Bark in the Middle of the Night
Christian Legal Centre has taken legal action against the Human Fertilisation and Embryology Authority, which it claims acted beyond its power in allowing Newcastle University and King's College London to create human-animal hybrid embryos for medical research, reports the BBC. The full Human Fertilisation and Embryology Bill, which updates existing legislation and would allow human stem cells ... (Sun, 26 Apr 2009 18:18:13 GMT)
The New Take on Aging: Your Body Is Actively Working Against You
This article in Scientific American reports on a study published in Cell that found certain genes in C. elegans that appear to switch on the aging process . (You can see where this is going, can't you?) (Sun, 26 Apr 2009 18:18:23 GMT)
The Long Line of Responsibility
Pharmas made headlines this weekend: The New York Times reports on charges that Eli Lilly has downplayed serious side effects of its schizophrenia drug Zyprexa. (Sun, 26 Apr 2009 18:18:44 GMT)
Computational Biology Illuminates How Cells Change Gears
Bioinformatics researchers just moved closer to unlocking the mystery of how human cells switch from "proliferation mode" to "specialization mode." This computational biology work could lead to new ideas for curbing unwanted cell proliferation -- including some cancers. This research could also improve our understanding of how organs and other complex tissues develop. (Mon, 27 Apr 2009 05:21:03 GMT)
Biological Basis For The Eight-hour Workday?
Scientists already know that some genes are controlled by the circadian clock and are turned on only one time during each 24-hour cycle. Now, researchers have found that some genes are switched on once every 12 or 8 hours, indicating that shorter cycles of the circadian rhythm are also biologically encoded. (Mon, 27 Apr 2009 05:21:23 GMT)
Matrix Genomics Launches Genetic Testing Services with Proprietary Risk Analysis Methodology
Matrix Genomics is a personal genomics company headquartered in Santa Fe, New Mexico, specializing in direct-to-consumer dna testing to assess an individual's genetic susceptibility for developing age-related inherited disorders. (Mon, 27 Apr 2009 07:01:00 GMT)
Matrix Genomics Launches Genetic Testing Services with Proprietary Risk Analysis Methodology
Matrix Genomics is a personal genomics company headquartered in Santa Fe, New Mexico, specializing in direct-to-consumer dna testing to assess an individual's genetic susceptibility for developing age-related inherited disorders. (Mon, 27 Apr 2009 07:01:00 GMT)
Ground broken on new lab at SDSU
South Dakota State University and its seed industry partners broke ground Friday for the $6.5 million Seed Technology Laboratory at SDSU's Innovation Campus in Brookings. The lab will the second building on the campus, the only university-affiliated research park in the state. Researchers there will develop, enhance and coordinate discovery, teaching, extension/outreach and technical service in ... (Mon, 27 Apr 2009 07:03:20 GMT)
The Personal Genome Project Deploys Isilon IQ Storage to Transform Genomic Research
out NAS to Store Public Database of Genomic and Trait Data for up to 100,000 Volunteers (Mon, 27 Apr 2009 10:00:00 GMT)
Bruker Daltonics Launches the Fastest and most Flexible MALDI-TOF/TOF Mass Spectrometer with Unsurpassed Performance ...
BILLERICA, Mass.----Bruker Daltonics today launches its next-generation ultrafleXtreme™ MALDI-TOF/TOF mass spectrometer, the only instrument combining true 1 kHz speed in both TOF and TOF/TOF modes with ultra-high performance and extreme flexibility for a broad variety of complementary research, clinical and applied proteomics applications. (Mon, 27 Apr 2009 10:00:00 GMT)
InforSense Used by Celera to Further Investigate Genetic Markers for Coronary Heart Disease
InforSense Ltd., the leading provider of next generation business and scientific intelligence solutions, today announced that Celera Corporation, a healthcare business delivering personalized disease management through a combination of products and services incorporating proprietary discoveries, is using InforSense to integrate internal molecular and public data sources to accelerate the ... (Mon, 27 Apr 2009 11:00:00 GMT)
InforSense Used by Celera to Further Investigate Genetic Markers for Coronary Heart Disease
InforSense Accelerates and Automates Diagnostic Biomarker Discovery (Mon, 27 Apr 2009 11:12:32 GMT)
City Honors junior earns slot at international science fair
Jimmitti Teysir is a “born scientist.” (Mon, 27 Apr 2009 11:13:15 GMT)
Bioalma Announces Full-Text Search Capabilities From Open Access Journals Through novo|seek
BOSTON and MADRID----Bioalma today announced at the Bio-IT World Conference & Expo, that novo|seek is now capable of executing full-text searches in all Open Access journals housed in PubMed Central. (Mon, 27 Apr 2009 12:00:00 GMT)
23andMe and Palomar Pomerado Health Partner to Give PPH Members Access to Their Genetic Information
San Diego Healthcare District Offers 23andMe Personal Genome Service™ at Health Centers to Encourage Preventive Care (PRWeb Apr 27, 2009) Read the full story at http://www.prweb.com/releases/23 (Mon, 27 Apr 2009 12:12:35 GMT)
Biotechnology Company, Replikins Ltd., Provided Advance Warning of Mexican H1N1 'Swine Flu' Virus Outbreak
Replikins Ltd. published a FluForecast® warning in April 7th, 2008, a year before the recent Mexico and California H1N1 cases. The company was able to state the likelihood of H1N1 outbreaks based on its patented Replikin Count genomics technology, which examines specific regions in virus genes which have been linked with past epidemics. (Mon, 27 Apr 2009 12:33:00 GMT)
Swine flu hasn't reached pandemic proportions
"We haven't had pandemic since 1968," Steven Saltzburg, director of the University of Maryland Center for Bioinformatics tells WTOP. (Mon, 27 Apr 2009 12:43:02 GMT)
Genome projects launched for three extreme-environment animals
( Beijing Genomics Institute at Shenzhen ) BGI-Shenzhen, in association with other research institutes, has launched three new genome projects that focus on animals living in extreme environments: the polar bear, the emperor penguin, and the Tibetan antelope. All three animals are threatened with extinction due to pollution and loss of environment. Next-generation sequencing technologies will be ... (Mon, 27 Apr 2009 13:13:27 GMT)
Thermo Fisher to Acquire Biolab for $120M
NEW YORK (GenomeWeb News) – Thermo Fisher Scientific has signed a deal to acquire Australian analytical instruments and life science consumables provider Biolab for A$175 million (US $120 million). (Mon, 27 Apr 2009 14:48:43 GMT)
Genome Project Using Isilon's NAS
NEW YORK (GenomeWeb News) – Isilon Systems said today that the Personal Genome Project will use the company's network-attached storage (NAS) platform to hold data generated by its human genomic and personalized medicine research efforts. (Mon, 27 Apr 2009 14:48:53 GMT)
How to Forget the Economy: Swine Flu Comes to a City Near You
Between bouts of frantic hand washing, we can scarcely get away from news about the swine flu outbreak. New York Times offers a good roundup of what's happened so far , including the situation in Mexico and the US declaring a public health emergency. (Mon, 27 Apr 2009 15:02:53 GMT)
The Round of 100
Daniel MacArthur at Genetic Future blogs about the news that George Church's Personal Genome Project " has called for the next wave of volunteers ." This round will include 100 people who will get their genome sequenced (at no cost to them). (Mon, 27 Apr 2009 15:03:03 GMT)
Looking for a Middle Ground
John Wilkins is trying to stir things up. Over at his Evolving Thoughts blog, he posts a question to the community about how religion and science fit together . Looking at it both ways, he asks the traditional question first: if you have a religion and in interest in science, how does that work? (Mon, 27 Apr 2009 15:04:24 GMT)
Just Sprinkle on a Few Proteins, and Voila
The Wall Street Journal reports on a study published in Cell Stem Cell describing how scientists " reprogrammed mature skin cells into an embryonic-like state by using proteins instead of genes, a key advance aimed at overcoming safety concerns in one of the hottest areas of biological research." (Mon, 27 Apr 2009 15:04:26 GMT)
Alnylam Says Chinese Patent Office to Grant Patent on RNAi Molecules
Alnylam Pharmaceuticals today announced that it has been notified that the Chinese patent office intends to grant a patent, assigned to the Max Plank Society and exclusively licensed to Alnylam, covering siRNAs. (Mon, 27 Apr 2009 15:32:54 GMT)
This Week in PLoS
In work published in PLoS Computational Biology this week, scientists have created a catalog of clinical phenotypic features of 174 disease genes in human mitochondria. (Mon, 27 Apr 2009 16:02:54 GMT)
Bay Biz Buzz: Onyx, Bayer halt Nexavar trial for melanoma
Emeryville-based Onyx Pharmaceuticals Inc. and Bayer HealthCare Pharmaceuticals have halted a Phase 3 trial Nexavar for patients with melanoma. An independent data-monitoring committee concluded the study would not achieve its goal of improved survival rates for patients who received Nexavar. (Mon, 27 Apr 2009 16:42:33 GMT)
RIKEN Omics Science Center to Expand Sequencing Center with $17M in Government Funding
The RIKEN Omics Science Center plans to update and expand its DNA sequencing infrastructure with $17 million in new grant funding from the Japanese government, the center said earlier this month. (Mon, 27 Apr 2009 17:17:53 GMT)
Taking Plant Biology from the Classroom to the Internet
A new article assesses the effectiveness of a new online course in the Plant Biology Department at Arizona State University, which was designed as a way for non-majors to fulfill their natural science requirement. The course, which students rated very highly, features written and animated materials to teach topics such as plant growth and their contribution to the biosphere. (Mon, 27 Apr 2009 17:25:38 GMT)
Consejo Superior de Investigaciones Cientificas, CSIC (Spanish National Research Council)
The Spanish National Research Council (Consejo Superior de Investigaciones Científicas, CSIC ) is the largest public research organisation in Spain, covering all fields of knowledge, from basic research through to advanced technological development. (Mon, 27 Apr 2009 18:07:03 GMT)
Vermillion Lays out Bonus Plan for Directors as it Seeks Chapter 11 Protection
Vermillion is seeking a bonus of at least $500,000 for its former CEO, now executive chair of the board, if its Chapter 11 reorganization plan is approved. (Mon, 27 Apr 2009 18:17:53 GMT)
Recent Research Papers of Note
Journal : Biomedical Chromatography : BMC, May Title : Limitation of immunoaffinity column for the removal of abundant proteins from plasma in quantitative plasma proteomics Authors : T Ichibangase; K Moriya; K Koike; K Imai In plasma proteomics, it is "essential" to prepare protein samples without high-abundance proteins with preparation techniques such as immunoaffinity capture, according to ... (Mon, 27 Apr 2009 18:33:12 GMT)
Functional Testing with Next-Gen Technology
Many in the sequencing world may already be familiar with Jay Shendure, the young investigator who, along with his colleagues in George Church's lab, helped to pioneer polony sequencing, a highly parallel, low-cost sequencing method. (Mon, 27 Apr 2009 19:18:03 GMT)
Signs of It Everywhere
Over at the Peanutbutter blog, Frank Gibson discusses semantic Web and which life science tools are making use of it. It's a quick glimpse of tools using RDF, which include UniProt and Bio2RDF. (Mon, 27 Apr 2009 19:32:53 GMT)
California Outpatient Centers Offering 23andMe Service
NEW YORK (GenomeWeb News) – California's Palomar Pomerado Health will offer 23andMe's genome service at its outpatient centers in San Diego, the companies said today. (Mon, 27 Apr 2009 19:47:53 GMT)
BGI Plans to Sequence Polar Bears, Penguins, Tibetan Antelope
NEW YORK (GenomeWeb News) – The Beijing Genomics Institute in Shenzhen plans to sequence the genomes of three animals that live in extreme weather environments and which could be in peril, including polar bears, emperor penguins, and the Tibetan antelope. (Mon, 27 Apr 2009 19:48:03 GMT)
PerkinElmer, Accelrys Integrate Cell Imaging Software
NEW YORK (GenomeWeb News) – PerkinElmer has integrated its image data management system for high content screening with Accelrys' data analysis and reporting platform, PerkinElmer. (Mon, 27 Apr 2009 19:48:13 GMT)
Celera Using InforSense's Data Platform
NEW YORK (GenomeWeb News) – InforSense today said that it has "developed a long-term relationship" with Celera, under which the molecular diagnostics firm is using InforSense's Translational Research Solution in automating experimental data analysis and molecular annotation. (Mon, 27 Apr 2009 19:48:23 GMT)
At NAS, Obama Calls for 'Historic Investment' in Basic Science
NEW YORK (GenomeWeb News) – In a speech to the National Academy of Sciences this morning, US President Barack Obama argued his case for increasing funding in basic science, particularly increases in the White House's budget proposal for 2010, and a plan to double the budgets for the National Science Foundation, the National Institute of Standards and Technology, and the Department of Energy's ... (Mon, 27 Apr 2009 20:03:23 GMT)
Open access advocate Philip E. Bourne to receive 2009 Benjamin Franklin Award
( University of California - San Diego ) Philip E. Bourne, a computational biologist and professor with the University of California, San Diego, will be presented with the 2009 Benjamin Franklin Award this week in recognition of his efforts as a leading advocate for the free and open dissemination of science and scientific data. (Mon, 27 Apr 2009 20:13:18 GMT)
CombiMatrix to Launch microRNA-Based Screen
CombiMatrix expects to have a microRNA-based cancer-screening test on the US market around the middle of next year, about five months after announcing that it had begun developing the product. (Mon, 27 Apr 2009 20:17:59 GMT)
Electronic Medical Records: Challenges to the President's Plan to Digitize Healthcare
Ready or not, electronic medical records are coming to a hospital near you. President Obama has dedicated $19 billion of the stimulus package for the digitization of medical records, and despite the clear advantages of this massive investment in health IT, Dr. James Pierce, chair of the Bioinformatics and Computer Science Department at University of the Sciences, warns of the significant ... (Mon, 27 Apr 2009 21:30:11 GMT)
Brain imaging skewed
Double dipping of data magnifies errors in functional MRI scans. (Mon, 27 Apr 2009 22:05:28 GMT)
DNA Of Uncultured Organisms Sequenced Using Novel Single-cell Approach
Scientists from the US Department of Energy Joint Genome Institute and the Bigelow Laboratory for Ocean Sciences have assembled high quality, contamination-free draft genomes of uncultured biodegrading microorganisms using a novel single cell genome sequencing approach. The research offers researchers a new method to access and decipher the information embedded in genomes of interest with only ... (Mon, 27 Apr 2009 22:17:32 GMT)
Obama promises spending boost for science
Ambitious target for economically tough times. (Tue, 28 Apr 2009 01:50:28 GMT)
Del. partnership awarded $17.4 million grant
For the third time, a partnership between Delaware hospitals and colleges has won major federal funding for biomedical research. (Tue, 28 Apr 2009 07:56:44 GMT)
Top tips on claiming SR&ED tax credits for software development
Canadian companies developing a new software product or process -- or improving an existing one -- may be eligible for substantial SR&ED (scientific research and experimental development) tax credits if they meet certain criteria. (Tue, 28 Apr 2009 09:09:31 GMT)
City of Hope Uses Isilon IQ to Advance Fight Against Life-Threatening Diseases
Renowned Biomedical Research and Treatment Facility Deploys Isilon Scale-out NAS to Power DNA Sequencing Workflow, Accelerating Cancer, Diabetes, and HIV/AIDS Research (Tue, 28 Apr 2009 10:00:00 GMT)
InforSense Used By Celera To Further Investigate Genetic Markers For Coronary Heart Disease
InforSense Ltd. (Tue, 28 Apr 2009 10:18:21 GMT)
Screening chip could speed up pathogen detection in animals
The microarray was developed by scientists at the UK Institute of Animal Health (IAH), and is said to be able to detect up to 300 different viruses that infect animals and humans, including farm livestock and birds. (Tue, 28 Apr 2009 10:47:56 GMT)
Quest Diagnostics Discovers New Genetic Mutations Affecting Cystic Fibrosis Screening
Quest Diagnostics scientists provide new insights into genetic factors affecting the accuracy and quality of Cystic Fibrosis (CF) carrier and newborn screening in three separate articles published in the May 2009 issue of The Journal of Molecular Diagnostics. Quest Diagnostics Incorporated (NYSE: DGX) is the world's leading provider of diagnostic testing, information and services. (Tue, 28 Apr 2009 11:18:22 GMT)
Compendia Bioscience Announces Collaboration with MDS Pharma Services to Deliver Novel Solution for Oncology Drug ...
Compendia Bioscience today announced a strategic collaboration with MDS Pharma Services to deliver OncoPredictor -- a novel solution for improved cancer drug development. OncoPredictor (Tue, 28 Apr 2009 12:00:00 GMT)
MDS Pharma Services Announces Collaboration with Compendia Bioscience, Inc. to Deliver Novel Solution for Oncology ...
MDS Pharma Services, a leading provider of innovative drug discovery and development solutions, has formed a strategic collaboration with Compendia Bioscience, Inc. to deliver a novel solution, OncoPredictor, to improve the development of drugs to treat cancer. (Tue, 28 Apr 2009 12:00:00 GMT)
Integrated Genomics, Inc. Announces Additions to its Scientific Advisory Board
CHICAGO----Integrated Genomics, Inc. , a leader in microbial genomic informatics and metabolic engineering, today announced the appointment of Todd Smith, Ph.D., Michael J. Sadowsky, Ph.D., and Catalina Lopez-Correa, MD, Ph.D. to its Scientific Advisory Board. (Tue, 28 Apr 2009 12:18:00 GMT)
The $68,000 Question: Knome Auctions Genome on eBay
Bio-IT World | For a starting bid of $68,000, you can join the select personal genome club courtesy of a historic charity auction offered by Knome and eBay. (Tue, 28 Apr 2009 12:28:42 GMT)
Electronic Medical Records: Challenges To The President's Plan To Digitize Healthcare
Ready or not, electronic medical records (EMRs) are coming to a hospital near you. President Barack Obama has devoted $20 billion to healthcare IT in the American Recovery and Reinvestment Act, and in February 2009, he announced his aspirations to have an electronic health record for each person in the U.S. by 2014. Dr. (Tue, 28 Apr 2009 13:17:54 GMT)
UCL, Pfizer To Develop Pioneering Stem Cell Sight Therapies
UCL has entered into a collaboration with the biopharmaceutical group Pfizer, negotiated by UCL Business, to advance development of stem cell-based therapies for age-related macular degeneration (AMD). (Tue, 28 Apr 2009 13:45:26 GMT)
UCL, Pfizer To Develop Pioneering Stem Cell Sight Therapies
UCL has entered into a collaboration with the biopharmaceutical group Pfizer, negotiated by UCL Business, to advance development of stem cell-based therapies for age-related macular degeneration (AMD). (Tue, 28 Apr 2009 13:51:53 GMT)
Toward a systems biology map of iron metabolism
( Virginia Tech ) Scientists at the Wake Forest University School of Medicine, the University of Manchester in the United Kingdom, and the Virginia Bioinformatics Institute at Virginia Tech have taken the first steps toward constructing a systems biology map of iron metabolism. The team has put together a general network of chemicals and reactions important for the many steps and reactions that ... (Tue, 28 Apr 2009 13:54:00 GMT)
City of Hope Using Isilon's NAS
NEW YORK (GenomeWeb News) – City of Hope, a National Cancer Institute Comprehensive Cancer Center, is using Isilon's network-assisted storage in its DNA sequencing-based studies, Isilon said today. (Tue, 28 Apr 2009 14:48:23 GMT)
Duke Medical Center to Use Wafergen System in Genotyping Studies
NEW YORK (GenomeWeb News) – Duke University Medical Center researchers will use WaferGen's real-time PCR system to conduct genotyping studies aimed at discovering genetic variants linked to breast cancer, the company said today. (Tue, 28 Apr 2009 14:48:33 GMT)
Toward a systems biology map of iron metabolism
Scientists at the Wake Forest University School of Medicine, the University of Manchester in the United Kingdom, and the Virginia Bioinformatics Institute at Virginia Tech have taken the first steps toward constructing a systems biology map of iron metabolism. The team has put together a general network of chemicals and reactions important for the many steps and reactions that constitute iron ... (Tue, 28 Apr 2009 15:30:25 GMT)
This Week in PNAS
Published in the most recent issue of PNAS , scientists at the University of Illinois at Urbana-Champaign have used molecular dynamics simulations to model the community interaction networks between tRNA and aminoacyl tRNA synthetase of a bacterial glutamyl-tRNA synthetase and an archaeal leucyl-tRNA synthetase complex. (Tue, 28 Apr 2009 15:48:04 GMT)
Obama at the Academy
As our sister news site reported , US President Barack Obama spoke before the National Academy of Sciences yesterday and called for an increase in funding for basic science. (Tue, 28 Apr 2009 16:02:53 GMT)
Like Office, But for Bioresearch
At the Bio-IT conference this week, Microsoft introduced Amalga Life Sciences, according to Bio-IT World . Amalga is part of Microsoft's "plan create a single information highway and data aggregation/modeling platform that spans basic research, clinical trials, health care delivery, and consumer health information needs." (Tue, 28 Apr 2009 16:03:13 GMT)
FDA OKs Emergency Use of MDx Swine Flu Test; CDC Recommends MDx Testing
NEW YORK (GenomeWeb News) – The US Food and Drug Administration yesterday authorized the emergency use of a molecular diagnostic assay to identify cases of swine flu. (Tue, 28 Apr 2009 17:02:53 GMT)
Paired Ends
Detlef Weigel has been elected as a member of the National Academy of Sciences . He is the director of the department of molecular biology at the Max Planck Institute for Developmental Biology in Tübingen, Germany. (Tue, 28 Apr 2009 17:03:03 GMT)
Autism breakthrough: Genetic links found
Researchers have found that people with autism share common genetic variations, a discovery that may improve diagnosis and offers the promise of developing treatments for the frustratingly mysterious disorder. (Tue, 28 Apr 2009 17:09:08 GMT)
Ambry Genetics Announces Illumina CSPro Certification for GA Sequencing
Ambry Genetics announced today that it has successfully completed Illumina CSPro certification for Genome Analyzer Sequencing, gaining entry to an elite group of Illumina genomics service providers globally. (Tue, 28 Apr 2009 17:17:00 GMT)
New Product Watch
According to the company, the new service provides biopharmaceutical clients with "a way to measure the genetics of drug metabolism in clinical trial patients — giving drug developers the opportunity to select patients that are more likely to respond." (Tue, 28 Apr 2009 17:17:54 GMT)
People in the News
The Obama Administration has nominated William Brinkman to be director of the US Department of Energy’s Office of Science. Brinkman is a senior research physicist at Princeton University and former vice president for research at Bell Labs and at Sandia National Laboratory. (Tue, 28 Apr 2009 17:18:04 GMT)
Funding Update
Supports the development of MGTAXA, a freely available software and a web server for taxonomic classification of metagenomic sequences with machine learning techniques. (Tue, 28 Apr 2009 17:18:14 GMT)
New Products
454 Life Sciences , a Roche company, has launched GS FLX Titanium series library paired-end adaptors for whole genome de novo sequencing and assembly. The adaptors allow users to generate 3-kilobase, 8-kilobase, and 20-kilobase paired-end libraries. (Tue, 28 Apr 2009 17:18:24 GMT)
IP Roundup
SRU Biosystems of Woburn, Mass., has received US Patent No. 7,524,625, "Real time binding analysis of antigens on a biosensor surface." The patent provides methods for detecting interactions between phage and antigen or antigen and antibody using biosensors. (Tue, 28 Apr 2009 17:34:03 GMT)
BioArray Briefs
California's Palomar Pomerado Health will offer 23andMe's genome service at its outpatient centers in San Diego, the organizations said this week. (Tue, 28 Apr 2009 17:34:14 GMT)
Services Startup Eureka Genomics Opens First Lab to Offer Next-Gen Sequencing, Data Analysis
Sensing a need for more services that combine next-generation sequencing with in-depth data analysis, startup Eureka Genomics recently acquired its first sequencer, an Illumina Genome Analyzer, for a new services facility in Hercules, Calif. (Tue, 28 Apr 2009 17:47:53 GMT)
Alzheimer's, asthma, cancer, malaria and TB focus of new Singapore grants
( Agency for Science, Technology and Research (A*STAR), Singapore ) Over 50 research grants totaling $24 million in US dollars have been awarded to Singapore universities, research institutes and hospitals to fund studies related to asthma and other immune system disorders, infectious diseases, aging and cancer. (Tue, 28 Apr 2009 18:13:28 GMT)
Gene Variants Hold New Clues to Autism
Researchers have identified new gene mutations -- also called gene variants -- that may boost the risk of autism spectrum disorders. (Tue, 28 Apr 2009 18:19:21 GMT)
Microsoft Unveils Software Platform For Life Science Research
Amalga Life Sciences is the latest product under the 3-year-old Microsoft Health Solutions banner. (Tue, 28 Apr 2009 18:49:34 GMT)
Three RNAi, miRNA Firms Record Strong Gains in Stock Value Since the End of 2008
Despite continued weakness in the economy, which has battered shares of virtually all public biotechnology and pharmaceutical firms, three of the publicly traded players in the RNAi and microRNA space have seen significant gains in the value of their stocks in recent months. (Tue, 28 Apr 2009 19:02:53 GMT)
Jolley: Talking With Dave Schubel, Cattleman, CBB Member, Lawyer, Nutritionist
Dave Schubel is a small town lawyer turned cattleman. The conversion wasn’t sudden and dramatic, mind you. Like most lawyers, he examined the proposition carefully and made a well-thought-out decision. (Tue, 28 Apr 2009 19:16:44 GMT)
Tecan, Innovatis Ink Co-marketing Plan
NEW YORK (GenomeWeb News) – Tecan said today that it will collaborate with Innovatis to jointly market robotic cell culture workstations and cell detection devices. (Tue, 28 Apr 2009 19:48:05 GMT)
MDS Pharma, Compendia to Develop Cancer PGx Platform
NEW YORK (GenomeWeb News) – MDS Pharma Services and Compendia Bioscience have collaborated to develop a pharmacogenomic platform for use in cancer patients and therapeutics research, MDS said today. (Tue, 28 Apr 2009 19:48:16 GMT)
SeqWright to Offer HairDx Test Service
NEW YORK (GenomeWeb News) – SeqWright today said that it will be the exclusive genetic testing provider for Pharmagenoma's HairDx test, which evaluates a patient's responsiveness to hair-loss treatment finasteride. (Tue, 28 Apr 2009 19:48:26 GMT)
Autism Linked to Genes That Govern How the Brain Is Wired
Two new papers published in the journal 'Nature' pinpoint important genetic variations that shed light on the etiology of autism spectrum disorders (Tue, 28 Apr 2009 20:00:20 GMT)
JNCI April 28 tip sheet
( Journal of the National Cancer Institute ) In addition to studies highlighted in two press releases, this JNCI issue includes articles on clinical trial designs to test the impact of exercise and weight control on breast cancer risk, the clusterin gene as a tumor suppressor in neuroblastoma, and a molecular test to predict outcome in mesothelioma. The last study shows that women survivors of ... (Tue, 28 Apr 2009 20:13:45 GMT)
Illumina Certifies Ambry Genetics
NEW YORK (GenomeWeb News) – Ambry Genetics said today that it has received certification to conduct sequencing using Illumina's genetic analysis technology. (Tue, 28 Apr 2009 20:18:28 GMT)
Research Highlights Genetic Risk for Autism
TUESDAY, April 28 (HealthDay News) -- Inheriting abnormal mutations of two common genes can raise the risk for developing autism, according to one of two new studies highlighting the complex genetic roots of the disorder. (Tue, 28 Apr 2009 21:03:34 GMT)
IP Update
According to the patent's abstract, "the invention provides a random or semi-random siRNA-encoding library." (Tue, 28 Apr 2009 21:17:54 GMT)
Yale to Use $5M for Dyslexia Genetics Studies
NEW YORK (GenomeWeb News) – The Yale School of Medicine has landed a $5.2 million foundation grant to conduct a large genomics study that will investigate genes involved in dyslexia. (Tue, 28 Apr 2009 22:03:04 GMT)
What the Autism Gene Finding Means for Parents
It's too soon to benefit babies, but maybe new therapies are somewhere down the road. (Tue, 28 Apr 2009 22:25:26 GMT)
Protein effects of hormone replacement therapy uncovered
( BioMed Central ) An in-depth proteomic analysis of the sera of 50 participants from the Women's Health Initiative hormone replacement therapy trial provides some explanations for the trial's clinical results. The study, published in Biomed Central's open access journal Genome Medicine, shows that estrogen upregulates proteins involved in several major body processes. (Tue, 28 Apr 2009 23:13:18 GMT)
U. of T. Student and Student Union Gearing Up For Lawsuit Against University
Why you’ll pay for a full course load even if you don’t take one. (Wed, 29 Apr 2009 00:00:24 GMT)
Autism Studies Target Genetic Link
New medical information confirms a genetic link to autism, reports Dr. Jennifer Ashton, in the largest study ever conducted on the subject. (Wed, 29 Apr 2009 00:30:05 GMT)
Researchers find common genetic variations in autistic people
Findings show that many autistic people have a deviation in a portion of their DNA that affects the way brain cells connect with one another. The discovery may lead to treatments. Researchers have found that many people with autism share common genetic variations, a discovery that may improve diagnosis and offers the promise of developing treatments for the frustratingly mysterious disorder. (Wed, 29 Apr 2009 00:44:50 GMT)
Toward A Systems Biology Map Of Iron Metabolism
Scientists have taken the first steps toward constructing a systems biology map of iron metabolism. They have put together a general network of chemicals and reactions important for the many steps and reactions that constitute iron metabolism. (Wed, 29 Apr 2009 01:17:24 GMT)
Two Indian firms to set up pre-clinical trials units in Malaysia
Two Indian firms to set up pre-clinical trials units in MalaysiaTwo Indian firms to set up pre-clinical trials units in Malaysia (Wed, 29 Apr 2009 05:39:35 GMT)
School notes
The Environmental Studies Academy and the city of Martinez will have a ribbon cutting and celebration from 10 a.m. to 2 p.m. May 3, for an environmentally designed parking lot at Ward and Las Juntas streets downtown. (Wed, 29 Apr 2009 07:15:59 GMT)
Clinical Genomics Continues Progress in Developing Biomarker Portfolio for Colorectal Cancer Testing
Clinical Genomics Pty Ltd, an Australian biotechnology company, announced today that Quest Diagnostics Incorporated, the world's leading provider of diagnostic testing, information and services, has agreed to provide milestone payments over the next two years to Clinical Genomics to further develop its portfolio of gene-based biomarkers associated with early onset of colorectal cancer. (Wed, 29 Apr 2009 08:37:00 GMT)
My Pharmiweb.com
AnaSpec Inc. Fremont, CA – April 28, 2009 Today AnaSpec announced the launch of its new headquarters in Fremont, California. (Wed, 29 Apr 2009 09:04:32 GMT)
CombiMatrix Receives Commitments For $8.25 Million in Registered Direct Offering
MUKILTEO, Wash., April 29, 2009 -- CombiMatrix Corporation announced today that is has obtained commitments from a group of select investors to purchase up to $8.25 million of its common stock and warrants in a registered direct offering. (Wed, 29 Apr 2009 09:30:00 GMT)
SâPORE COMPANY SAYS ITS TEST KIT CAN DETECT SWINE FLU
SINGAPORE, April 29 (Bernama) â A Singapore company which last year produced the âVereFluâ portable test kit that is capable of rapidly detecting all major types of influenza strains including the deadly avian flu today said its latest test kit is able to detect the variant strain of swine flu (H1N1) that has currently caused a global concern. (Wed, 29 Apr 2009 09:51:17 GMT)
CombiMatrix Updates Influenza-Detection System For Swine Flu
MUKILTEO, Wash., April 29, 2009 -- CombiMatrix Corporation announced today that it has updated its Influenza-Detection Microarray to include sequence information of the latest strain of Swine Flu. (Wed, 29 Apr 2009 10:00:00 GMT)
CHOP, Penn research points to genetic link in autism
By analyzing DNA from more than 2,000 autistic children, researchers have uncovered the best evidence yet for genetic links to the disorder - all tied to the way brain cells form and dissolve connections. (Wed, 29 Apr 2009 10:01:01 GMT)
Panasas and Dell Introduce Integrated, High-Performance Solution for Life Sciences Research
Companies Deliver Breakthrough Ease-of-Use and Performance to Accelerate Research and Innovation for All Life Science Disciplines (Wed, 29 Apr 2009 10:42:13 GMT)
2009/04/29
A Singapore company which last year produced the ‘VereFlu’ portable test kit that is capable of rapidly detecting all major types of influenza strains including the deadly avian flu today said its latest test kit is able to detect the variant strain of swine flu (H1N1) that has currently caused a global concern. (Wed, 29 Apr 2009 10:42:37 GMT)
Singapore test kit can detect swine flu ‘within two hours’
SINGAPORE, April 29 — A Singapore company which last year produced the VereFlu portable test kit that is capable of rapidly detecting all major types of influenza strains including the deadly avian flu today said its latest test kit is able to detect the variant strain of swine flu (H1N1) that has currently caused a global concern. The company, Veredus Laboratories said the VereID Biosystem and ... (Wed, 29 Apr 2009 10:55:16 GMT)
Protein effects of hormone replacement therapy uncovered
An in-depth proteomic analysis of the sera of 50 participants from the Women's Health Initiative (WHI) hormone replacement therapy trial provides some explanations for the trial's clinical results. The study, published in Biomed Central's open access journal Genome Medicine, shows that estrogen upregulates proteins involved in several major body processes. (Wed, 29 Apr 2009 13:00:18 GMT)
CHOP, Penn research points to genetic link in autism
By analyzing DNA from more than 2,000 autistic children, researchers have uncovered the best evidence yet for genetic links to the disorder - all tied to the way brain cells form and dissolve connections. (Wed, 29 Apr 2009 13:31:06 GMT)
Meet the Obama technology team
A broad range of technology and science advisors will provide insight and analysis to the President. (Wed, 29 Apr 2009 13:51:02 GMT)
DNA barcoding of mosquito species deployed in bid to end elephantiasis
( JRS Biodiversity Foundation ) The University of Ghana, supported by the Philadelphia-based JRS Biodiversity Foundation, is pioneering the use of DNA "barcodes" to map menacing mosquito species in West Africa that spread lymphatic filariasis, commonly known as elephantiasis. The ability to precisely identify mosquito species is a promising advance in the battle against LF, an often disfiguring ... (Wed, 29 Apr 2009 14:13:20 GMT)
New Singapore Grants To Focus On Alzheimer's, Asthma, Cancer, Malaria And TB
Over 50 research grants totaling $24 million in U.S. dollars have been awarded to Singapore universities, research institutes and hospitals to fund studies related to asthma and other immune system disorders, infectious diseases, aging and cancer. (Wed, 29 Apr 2009 14:20:02 GMT)
A Compelling Look at Variation
When Greg Cooper applied to two postdoc positions at the University of Washington — one with Evan Eichler, the other with Debbie Nickerson — what he really wanted was to move from mammalian genomics research to work that had more direct application in understanding human genetics and population characterization. (Wed, 29 Apr 2009 14:33:23 GMT)
Luminex Corporation Settles Legal Dispute
AUSTIN, Texas----Luminex Corporation today announced that it has settled the pending litigation with The Research Foundation for the State University of New York and the Board of Trustees of the University of Illinois . (Wed, 29 Apr 2009 14:44:00 GMT)
No Time to Find Out Where They Keep the Toner
The US Department of Health and Human Services now has a leader with Kathleen Sebelius being confirmed and sworn in yesterday. The Senate voted 65 to 31 to confirm her nomination. (Wed, 29 Apr 2009 15:17:53 GMT)
You'll Have to Buy Your Own Bics Now
Doctors and medical researchers should not accept drug samples, gifts, or money from drug and medical device companies, says a report from the Institute of Medicine, which is part of the National Academy of Sciences. (Wed, 29 Apr 2009 15:18:03 GMT)
Abolishing Serfdom in Academia
In an op-ed in the New York Times , Columbia's Mark Taylor says that " graduate education is the Detroit of higher learning " and that it needs to be revamped. (Wed, 29 Apr 2009 15:18:13 GMT)
Wash Your Hands Before and After You Read This
Sandra Porter has a few posts on using digital biology to take a gander at the swine flu that's all the rage. In the first, she uses the NCBI Influenza Virus Resource to see which animals are influenza hosts (the list includes the blowfly, which Porter doubts). (Wed, 29 Apr 2009 15:32:53 GMT)
DNA Software, Inc. Honored as One of the 2009 "Michigan 50 Companies to Watch"
DNA Software, Inc. is a unique life sciences technology company that conducts original wet lab research, develops advanced bioinformatics tools, sells molecular biology software, and provides advanced scientific consulting. (Wed, 29 Apr 2009 15:35:00 GMT)
This Week in Genome Research
In the April issue of Genome Research , Harvard's Martha Bulyk and Josh LaBaer led research that scanned yeast transcription factors for their binding specificity across the genome. (Wed, 29 Apr 2009 16:03:14 GMT)
Systems Biology Map Of Iron Metabolism
Scientists at the Wake Forest University School of Medicine, the University of Manchester in the United Kingdom, and the Virginia Bioinformatics Institute at Virginia Tech have taken the first steps toward constructing a systems biology map of iron metabolism. (Wed, 29 Apr 2009 16:18:47 GMT)
What MS Downturn? Bruker is Latest to Launch New Instrument with ultraXtreme MALDI-TOF/TOF
Despite an environment that is shaking out to be one of the most challenging for the mass spectrometry business in recent memory, vendors are continuing to push out new instruments. (Wed, 29 Apr 2009 16:47:53 GMT)
NCI 'GO' Grant Providing $10M for Cancer Proteomics
This week the National Cancer Institute issued a request for applications for exploratory research in human cancer proteomics as part of its participation in the Research and Research Infrastructure Grand Opportunities Program. (Wed, 29 Apr 2009 16:48:03 GMT)
Young Investigator Profile
Greg Cooper is doing a joint postdoc project with Evan Eichler and Debbie Nickerson in which he aims to connect structural variation data from the human genome to the common traits linked to them. To this end, studying variation in HapMap samples has become a major focus of Cooper’s lab work. (Wed, 29 Apr 2009 18:03:04 GMT)
New Releases
Personal genomics company Matrix Genomics is offering DNA home testing kits for Alzheimer's disease, breast cancer and heart attack risk. (Wed, 29 Apr 2009 18:03:14 GMT)
New computer program promises to be 'Rosetta Stone' for chemical names
In an advance that will help speed global development of new drugs and patenting of new commercial and industrial products, a scientist in New Mexico is reporting development of the first computer program that can quickly and accurately translate complex chemical names from one language into another. (Wed, 29 Apr 2009 18:15:47 GMT)
Hamner Scientists Receive Multiple Awards At The Society of Toxicology 48th Annual Meeting & ToxExpo
RESEARCH TRIANGLE PARK , N.C . – Multiple scientists at The Hamner Institutes for Health Sciences (The Hamner) were recently recognized at the Society of Toxicology (SOT) 48 th Annual Meeting and ToxExpo for their contributions to the toxicology and risk assessment. (Wed, 29 Apr 2009 18:33:42 GMT)
Luminex Settles Dispute with SUNY, University of Illinois
NEW YORK (GenomeWeb News) – Luminex today said that it had settled pending litigation with the Research Foundation for the State University of New York and the Board of Trustees of the University of Illinois, under which it will pay the universities a one-time cash payment of $4.35 million with no admission of guilt. (Wed, 29 Apr 2009 19:02:53 GMT)
Quest Licenses Clinical Genomics' Biomarkers
NEW YORK (GenomeWeb News) – Quest Diagnostics has licensed Clinical Genomics' biomarkers associated with colorectal cancer in order to develop them as a detection tool, Clinical Genomics said today. (Wed, 29 Apr 2009 19:03:03 GMT)
VCU Opens Molecular Medicine Research Center
NEW YORK (GenomeWeb News) – The Virginia Commonwealth University School of Medicine has opened a new medical research facility that will house a variety of studies that will involve genomics, DNA sequencing, and proteomics efforts. (Wed, 29 Apr 2009 19:03:13 GMT)
U of Arizona OTT, Pacific Northwest VC Shop Aim to Develop Startups Based on UA Inventions
The University of Arizona Office of Technology Transfer said yesterday that it has signed a memorandum of understanding with Pacific Northwest-based venture-development firm the University Funds to create startup companies based on research at the university. (Wed, 29 Apr 2009 19:32:53 GMT)
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