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BioInformatics, LLC New Report - Capitalizing on New Opportunities for Stem Cell Products
BioInformatics, LLC announces the pending release of its newest report, Capitalizing on New Opportunities for Stem Cell Products. As a result of the March 9, 2009 reversal of the 2001 restrictions on federal funding of human embryonic stem cell research, suppliers of stem cell related products are in need of a fast, accurate assessment of new opportunities in the stem cell products market. (Tue, 07 Apr 2009 19:39:00 GMT)
ArrayIt Teams with Parkinson's Institute
NEW YORK (GenomeWeb News) – ArrayIt has inked a collaboration with the Parkinson's Institute to discover biomarkers for Parkinson's disease, the Sunnyvale, Calif.-based firm said today. (Tue, 07 Apr 2009 19:43:23 GMT)
Pancreatic cancer biomarkers list created
BALTIMORE, April 7 (UPI) -- A Johns Hopkins University scientist has created a compendium of 50,000 possible pancreatic cancer biomarkers and says he's asked his colleagues to study it. (Tue, 07 Apr 2009 19:45:31 GMT)
Paired Ends
Helaman Escobar is leaving his post as the director of the DNA sequencing and genomics core facility at the University of Utah in order to head the DNA sequencing operation at Eurofins' Operon/MWG in Huntsville, Ala. The University of Utah is currently seeking a replacement for his position. (Tue, 07 Apr 2009 19:58:04 GMT)
Short Reads
A new UK genome sequencing center is slated to open soon, the UK's Biotechnology and Biological Sciences Research Council said last week. BBSRC said that the Genome Analysis Centre, located in the Norwich Research Park, will become operational over the next two months and open officially in June. (Tue, 07 Apr 2009 20:13:13 GMT)
Helicos Expands Applications for HeliScope as Initial Product Revenues Trickle in
Over the last few months, Helicos has installed its single-molecule sequencer in at least two institutes. (Tue, 07 Apr 2009 20:30:03 GMT)
Pancreatic cancer biomarkers list created
A Johns Hopkins University scientist has created a compendium of 50,000 possible pancreatic cancer biomarkers and says he's asked his colleagues to study it.Associate Professor Dr. Akhilesh Pandey, founder and director of the Institute of Bioinformatics in Bangalore, India, said with limited resources available for the testing needed to be considered a bona fide biomarker of clinical value, it's ... (Tue, 07 Apr 2009 20:48:13 GMT)
Navigenics Names Jonathan Lord, MD to Serve as President and Chief Executive Officer
FOSTER CITY, Calif.----Navigenics, a leading personal genomics testing company, announced today that Jonathan "Jack" T. Lord, MD, has been appointed by the Board of Directors to serve as President and Chief Executive Officer of the firm. (Tue, 07 Apr 2009 21:00:00 GMT)
ABI/MDS Launch MALDI MS, Continuing Efforts to Reenergize Their Mass Spec Joint Venture
Life Technologies' Applied Biosystems and its mass spectrometry joint-venture partner MDS today launched the AB Sciex TOF/TOF 5800 mass spectrometer, the second major launch by the firms in the past six months as they try to turn around a slumping mass-spec operation. (Tue, 07 Apr 2009 21:27:53 GMT)
NDCR 2009 Provides First-of-its-Kind Reference for Pharmacists and Healthcare Practitioners
NDCR 2009 by Dr. Daniel A. Hussar provides a first-of-its-kind reference for pharmacists and healthcare practitioners. The book details the 158 drugs that have been marketed in the U.S. during the 2002-2008 period, and features comparisons to previously marketed drugs, specific advantages and disadvantages of each, and ratings for each new drug based on comparisons with related agents. (Tue, 07 Apr 2009 21:28:30 GMT)
Lord leaving Humana for CEO job at Navigenics
Dr. Jonathan Lord, Humana's chief innovation officer, is leaving the Louisville health insurer to be chief executive of a California genomics testing company. (Tue, 07 Apr 2009 21:29:50 GMT)
UPI NewsTrack Health and Science News
Spitzer looks for prebiotic chemicals ... Pancreatic cancer biomarkers list created ... NASA selects Orion heat shield material ... Fluorescent brain cells may guide surgeons ... Health/Science news from UPI. (Tue, 07 Apr 2009 21:45:31 GMT)
Dr. Jonathan Lord leaving Humana to join genomics firm
Humana Inc.’s senior vice president and chief innovation officer, Dr. Jonathan Lord, will leave the company May 1 to become CEO of a Navigenics Inc. in Foster City, Calif. (HUM) (Tue, 07 Apr 2009 21:47:53 GMT)
Infinity Announces Leadership Promotions
CAMBRIDGE -- Infinity Pharmaceuticals, Inc. , an innovative cancer drug discovery and development company, today announced two leadership promotions: John J. Keilty to vice president, information technology and informatics, and Joseph F. McPherson to vice president, facilities and operations. (Wed, 08 Apr 2009 02:00:37 GMT)
Poison -- It's What's For Dinner: Hunt Narrows For Genes That Let Packrats Eat Creosote
As the US Southwest grew warmer from 18,700 to 10,000 years ago, juniper trees vanished from what is now the Mojave Desert, robbing packrats of their favorite food. Now, biologists have narrowed the hunt for detoxification genes that let the rodents eat toxic creosote bushes that replaced juniper. The have identified 24 candidate genes. (Wed, 08 Apr 2009 03:30:47 GMT)
This Week in Science
After eight years at the Howard Hughes Medical Institute, Thomas Cech is stepping down . While Cech led HHMI, its endownment grew by 60 percent and it established its own research campus, Janelia Farm. Cech will be returning to his lab at the University of Colorado, Boulder, to continue his work into telomerase. (Wed, 08 Apr 2009 07:42:53 GMT)
Covaris starts DNA shearing service
Covaris Incorporated announced the introduction of DNA shearing service using Covaris instruments and technology. (Wed, 08 Apr 2009 08:46:07 GMT)
Town names streets after Terry Pratchett's Discworld books
Author visits Somerset town to unveil roads which take their names from his fantasy series If you go down to Wincanton in Somerset today you can wander down Peach Pie Street and Treacle Mine Road, named after Sir Terry Pratchett's fantasy series Discworld. Pratchett visited the town today to unveil the road names at a new housing estate, and was greeted by hundreds of fans – many dressed in ... (Wed, 08 Apr 2009 09:29:08 GMT)
SeqWright's Clinical Trial Support Contributes To The Approval Of Two HPV Diagnostic Systems
SeqWright Inc., an international leader in the field of contract genomic services, announced today its involvement in Hologic's (formerly Third Wave Technologies) successful clinical trials of two Human Papillomavirus (HPV) in vitro diagnostic tests. (Wed, 08 Apr 2009 10:15:53 GMT)
Australia pick Symonds to face Pakistan
• Troubled all-rounder returns after counselling • Ponting, Hussey and Johnson rested ahead of Ashes Andrew Symonds has been included in Australia's squad for their limited-overs series against Pakistan, which starts this month. The injured fast bowler Brett Lee and all-rounder Shane Watson have also been recalled but Ricky Ponting, Mike Hussey and Mitchell Johnson have been left out, with a ... (Wed, 08 Apr 2009 10:19:20 GMT)
McLaren charged over Hamilton row
• Team accused of breaching International Sporting Code • Sacking of sporting director is confirmed McLaren will appear before an extraordinary meeting of the FIA World Motorsport Council in Paris on 29 April to answer charges relating to being in breach of the International Sporting Code, the FIA has confirmed. The summons follows Lewis Hamilton's exclusion from the Australian grand prix for ... (Wed, 08 Apr 2009 10:26:12 GMT)
Civil legal aid gap being plugged by private cover, critics warn
• 'After the event' insurance funding high-profile cases • Experts say trend may harm access to justice Government plans to rely on private companies funding the cost of civil cases are failing to address the gap in accessing justice, experts say, as pressure on public funding available for civil legal aid continues. Cases being funded by "after the event insurance" (ATE), where insurers cover ... (Wed, 08 Apr 2009 10:37:43 GMT)
Scientists Use Advanced Genomic Technology from Applied Biosystems to Uncover Profiles of Gene Activity from Single ...
CARLSBAD, Calif.----Applied Biosystems, a division of Life Technologies Corporation today announced that researchers have discovered comprehensive profiles of gene activity from single cells using the SOLiD™ System, its next-generation genomic analysis platform. (Wed, 08 Apr 2009 11:30:00 GMT)
BioInformatics, LLC New Report - Capitalizing On New Opportunities For Stem Cell Products
BioInformatics, LLC announces the pending release of its newest report, Capitalizing on New Opportunities for Stem Cell Products. As a result of the March 9, 2009 reversal of the 2001 restrictions on federal funding of human embryonic stem cell research, suppliers of stem cell related products are in need of a fast, accurate assessment of new opportunities in the stem cell products market. (Wed, 08 Apr 2009 12:15:32 GMT)
Komen to Fund Cancer PGx Research through New Grants
NEW YORK (GenomeWeb News) – Susan G. Komen for the Cure, a non-profit organization dedicated to funding breast cancer research and education, has awarded $60 million in grants to US and international researchers, including nearly $19 million to fund research into pharmacogenomics. (Wed, 08 Apr 2009 14:27:53 GMT)
SeqWright to Take Stake in LaserGen
NEW YORK (GenomeWeb News) – SeqWright is set to make an undisclosed equity investment in LaserGen, a Houston-based developer of chemistries for next-generation sequencing applications. (Wed, 08 Apr 2009 14:43:34 GMT)
Gen-Probe Completes Tepnel Acquisition
NEW YORK (GenomeWeb News) – Gen-Probe today said that it has completed its acquisition of Tepnel Life Sciences for £92.8 million (US$136.4 million). (Wed, 08 Apr 2009 14:43:57 GMT)
Navigenics names Jonathan Lord CEO
Personal genomics testing company Navigenics Inc. named Dr. Jonathan Lord president and chief executive. (Wed, 08 Apr 2009 14:55:18 GMT)
TRADE NEWS: Agilent Technologies Appoints The Research Institute at Nationwide Children's Hospital as Certified ...
SANTA CLARA, Calif., & COLUMBUS, Ohio----Agilent Technologies Inc. today announced that The Research Institute at Nationwide Children's Hospital has achieved Certified Service Provider status for Agilent microarrays. (Wed, 08 Apr 2009 15:00:00 GMT)
CLC bio Enjoys Playing the (April) Fool
Bio-IT World | Today's announcement from Danish informatics firm CLC bio that licenses for its flagship Genomics Workbench product were out of stock due to a glitch with a Russian supplier was a successful April's Fool. (Wed, 08 Apr 2009 15:09:09 GMT)
Dietrich Stephan Plans Individualized Health Institute in Virginia
Washingon Business Journal| Dietrich Stephan, co-founder of personal genomics company Navigenics, is drawing up plans for a $245-million research institute in Northern Virginia -- the Ignite Institute for Individualized Health. (Wed, 08 Apr 2009 15:09:40 GMT)
The Bourne Commendation: Open Access Evangelist Wins 2009 Benjamin Franklin Award
Bio-IT World | Australian open-access evangelist Philip Bourne, a prolific computational biologist at UCSD, journal editor and co-founder of SciVee.tv, has been selected to win the 2009 Benjamin Franklin Award, which will be presented on Tuesday April 28 at the Bio-IT World Expo. (Wed, 08 Apr 2009 15:09:50 GMT)
Lordy Me: Navigenics Names Jonathan Lord New CEO
Bio-IT World | Navigenics marked the first anniversary of its personal genomics service by appointing ex-Humana executive Jonathan Lord as its new president and CEO, succeeding Mari Baker. (Wed, 08 Apr 2009 15:10:10 GMT)
Women the World Over Rejoice
A new DNA test from Qiagen outperforms Pap smears in detecting the virus behind cervical cancer, reports the New York Times . An article in the New England Journal of Medicine looks into the effectiveness of human papillomavirus testing versus cytologic testing versus visual inspection of the cervix with acetic acid on of cervical cancer incidence and death in India. (Wed, 08 Apr 2009 15:58:02 GMT)
Adding the 'Visual' to the 'Mapper'
Attila Chordash has been playing around with 23andMe's new Haplogroup Tree Mutation Mapper that is part of the company's new Labs section. Chordash compares the section to Google Labs and at the 23andMe blog they say this section of their service will be "less refined" and "somewhat more fluid." (Wed, 08 Apr 2009 15:58:14 GMT)
A New One Steps In
On its blog, Navigenics has announced that its new president and CEO will be Jonathan Lord . Previously, Lord was the chief innovation officer at Humana in Louisville, and before that he was president of Boston's Health Dialog. (Wed, 08 Apr 2009 15:58:26 GMT)
This Week in Genome Research
In early online edition this week, Canadian scientists used whole genome sequencing on three strains of Streptococcus pneumoniae that had been made resistant to the antibiotic linezolid . Comparative analysis revealed mutations in the 23S rRNA gene in all mutants and at G2576T, a previously recognized resistance mutation. (Wed, 08 Apr 2009 15:58:36 GMT)
NSF ... NSFW
Senators Charles Grassley (R-Iowa) and Barbara Mikulski (D-Md) say in a letter that NSF has not responded adequately to their investigation into NSF employees who viewed pornographic material while at work . According to the New York Times , the allegations involve more than 30 employees and extend over 10 years. (Wed, 08 Apr 2009 16:12:53 GMT)
The New Monolith
Pfizer unveils what the company's structure will look like after it swallows up Wyeth . According to the Wall Street Journal , Pfizer will be splitting its research and development efforts in two: the small molecule section will be overseen by Pfizer's current R&D chief Martin Mackay, and the biologic section will be led by Wyeth's R&D chief Mikael Dolsten. (Wed, 08 Apr 2009 16:13:03 GMT)
Infinity Announces Leadership Promotions
CAMBRIDGE -- Infinity Pharmaceuticals, Inc. , an innovative cancer drug discovery and development company, today announced two leadership promotions: John J. Keilty to vice president, information technology and informatics, and Joseph F. McPherson to vice president, facilities and operations. (Wed, 08 Apr 2009 16:18:50 GMT)
Young Investigator Profile
Qian's lab is focused on better understanding cell signaling and discovering diagnostic protein biomarkers for human diseases, such as diabetes, through the development and application of novel mass spectrometry-based proteomics approaches capable of measuring changes in protein abundances and post-translational modifications from mammalian cells, tissues, and biofluids. (Wed, 08 Apr 2009 17:43:03 GMT)
Experts Review Cancer Genomics Progress
Wellcome Trust Sanger Institute Cancer Genome Project members Michael Stratton, Peter Campbell, and Andrew Futreal penned the review, which discuss everything from the general role of somatic mutations in cancer to cancer genome sequencing. (Wed, 08 Apr 2009 17:58:00 GMT)
Ohio Hospital Named Agilent CSP for Assays
NEW YORK (GenomeWeb News) – The Research Institute at Nationwide Children's Hospital has been named a certified service provider for Agilent Technologies' array-based comparative genomic hybridization and gene expression assays on the Agilent platform. (Wed, 08 Apr 2009 17:58:10 GMT)
U of Cincinnati Lands $22.7M from NCRR
NEW YORK (GenomeWeb News) – The University of Cincinnati will use $22.7 million from the National Institutes of Health to start a translational research center that will partner with hospitals in the region to delve into a variety of biomedical science areas including studies that involve proteomics, gene transfer, bioinformatics, imaging, and other applications. (Wed, 08 Apr 2009 17:58:20 GMT)
Helicos Appeals European Patent Held by Illumina
NEW YORK (GenomeWeb News) - Helicos BioSciences has decided to appeal a European Patent Office decision to maintain, in an amended form, a sequencing-related patent owned by Illumina, Helicos said in a filing with the US Securities and Exchange Commission last week. (Wed, 08 Apr 2009 18:42:53 GMT)
Canada Grants Millions for 'Omics Research
NEW YORK (GenomeWeb News) - The Canada Foundation for Innovation has granted C$26 million (US$21.1 million) to a number of institutions and centers to support a broad array of research that includes many biomedical studies involving proteomics, genetics, molecular biology, and biomedical imaging projects. (Wed, 08 Apr 2009 18:43:03 GMT)
Nuvera, J&J's Veridex Ink Deal to Develop, Market Breast Cancer Drug Response Dx
Nuvera Biosciences has penned a licensing agreement with Veridex to develop and commercialize assays to gauge treatment response to tamoxifen and taxane-containing chemotherapies, the companies said this week. (Wed, 08 Apr 2009 18:58:06 GMT)
Selling Genomics Services Unit to Beckman, Clinical Data Focuses on Rx, Biomarker Programs
Clinical Data's sale of its genomic services unit to Beckman Coulter will not affect its pharmacogenomics efforts, but will enable it to better focus on its drug development and biomarker discovery programs, the company said this week. (Wed, 08 Apr 2009 18:58:17 GMT)
Investment Bank Reports Advantage of CLIA Labs in Driving Adoption of OncotypeDX
The US Food and Drug Administration's stalled attempt to regulate complex laboratory-developed genetic tests has helped Genomic Health's Oncotype DX assay to attain dominance in the breast cancer-recurrence screening market, according to a report by investment bank Thomas Weisel Partners. (Wed, 08 Apr 2009 18:58:27 GMT)
Scoop!: How two students set up an ice cream business
Two years ago Carlo Del Mistro, 27, from Lake Como in northern Italy, was working as a strategist with Lehman Brothers in London – but he didn't see his future in banking. He left to take a full-time MBA at London Business School, where his wife Simone was also doing a one-year Masters in finance course. (Wed, 08 Apr 2009 23:31:38 GMT)
NCBS scientists undertake research on cancer pathway based on Hedgehogs protein
Scientists at National Centre for Biological Sciences (NCBS) have discovered a new twist to a crucial signalling pathway, involved in development, based on the protein Hedgehog. This pathway could possibly have an impact on future cancer research. (Thu, 09 Apr 2009 02:46:13 GMT)
OncQuest Labs novel tests covering grey areas in cancer biology
OncQuest Laboratories Ltd, a pioneer and the leader in the Indian Oncology clinical testing market, has expanded its test-range covering grey areas of cancer biology. (Thu, 09 Apr 2009 02:46:44 GMT)
College course to focus on stem cells
A new course of study at California State University Channel Islands this fall will train students to conduct research that could lead to cures for diabetes, spinal cord injuries or cancer. The California Institute for Regenerative Medicine recently awarded the Camarillo-based university a threeyear, $1. (Thu, 09 Apr 2009 03:24:33 GMT)
Latest Developments In Microplate Technology
Porvair Sciences has announced that it will showcase its latest developments in microplate technology at the forthcoming Achema 2009 exhibition in Frankfurt, Germany. (Thu, 09 Apr 2009 05:23:00 GMT)
We've changed our look!
Welcome to our brand new look. We've redesigned our site to give you quicker and clearer access to the information you need. Let us know if you like it, and even more so if you'd like us to fine tune it further. (Thu, 09 Apr 2009 09:33:43 GMT)
BioTek Instruments Awarded Best Large Company In VBM's 2009 Best Places To Work
As a first-time participant, BioTek Instruments, Inc., recently secured top honors in the Best Places to Work Awards, Large Companies category. (Thu, 09 Apr 2009 09:41:03 GMT)
Rhythmic Genomics -- The Yeast Metronome And The Walk Of Life
New genome sequence information from the humble baker's yeast has revealed surprising variation in a set of genes that can be thought of as nature's oldest clock. In a paper published in Genome Research scientists show how ribosomal RNA genes that are essential to all Earth's organisms provide insight into how genomes maintain their integrity on their evolutionary journey. (Thu, 09 Apr 2009 10:13:42 GMT)
Agilent Tech Bets New Array-Analysis Software Will Woo Systems Biologists
Agilent Technologies this week launched GeneSpring GX 10.0, the next generation of its gene-expression bioinformatics platform. GeneSpring GX 10 offers tools for systems-level data interpretation and pathway analysis and was designed with systems biologists in mind, company officials said. (Thu, 09 Apr 2009 10:16:18 GMT)
So Snoopy Couldn't Run (At Least He Could Fly)
In whippets, a type of racing dog, a single copy of a mutated gene for myostatin helps them be the fastest sprinters on the track, report researchers led by Elaine Ostrander from the National Human Genome Research Institute. (Thu, 09 Apr 2009 10:16:30 GMT)
Tough Times for GWAS
Here's a post from the Annals of Neurology blog reacting to the problems that arose as scientists realized they could identify individuals even from seemingly "anonymized" pooled DNA samples. (Thu, 09 Apr 2009 10:16:41 GMT)
Genetic Links for Lupus
The Wall Street Journal covers news from Genentech , which tracked two genes related to lupus, "raising hopes of earlier diagnosis and better targeted treatment of the auto-immune disease," the article says. (Thu, 09 Apr 2009 10:17:03 GMT)
This Week in PLoS
Princeton researchers report in PLoS Computational Biology that they developed a model of cellular growth in Saccharomyces cerevisiae that's based on the expression levels of a set of small genes. (Thu, 09 Apr 2009 10:17:16 GMT)
TcLand Expression, Leader in Gene Expression Biomarkers in Immunology, Strengthens Its Board of Directors
NANTES, France----TcLand Expression, a world-leading company in the field of gene expression biomarkers in immunology, is honoured to announce the appointment of Mr Patrick F. Terry as new member of its Board of Directors. (Thu, 09 Apr 2009 11:00:00 GMT)
New Genomics Tools from Applied Biosystems Broaden Applications of RNA Expression Analysis
CARLSBAD, Calif.----Applied Biosystems, a division of Life Technologies Corporation , today announced the release of a new set of genomic analysis tools to aid disease research and agricultural studies. (Thu, 09 Apr 2009 11:30:00 GMT)
Jivan Focuses on Solutions for Transcriptome Sequencing
Jivan announced today that it will provide bioinformatics solutions for high-throughput transcriptome sequencing and expression. Leveraging Jivan's industry-leading bioinformatics infrastructure for analysis of mRNA in biological samples, Jivan will provide (Thu, 09 Apr 2009 12:15:00 GMT)
NIAID Funding Malaria Genomics, Field Studies
NEW YORK (GenomeWeb News) – The National Institute of Allergy and Infectious Diseases will give $13.8 million in grants in the next year to support the creation of centers that will use molecular, clinical, and field research approaches to develop greater knowledge about malaria. (Thu, 09 Apr 2009 14:02:05 GMT)
GenoLogics Integrates Lab Software with ABI's SOLiD
NEW YORK (GenomeWeb News) – GenoLogics and Applied Biosystems have struck a partnership to integrate GenoLogics' lab and data management solution with the ABI SOLiD System. (Thu, 09 Apr 2009 14:16:13 GMT)
Cell Biosciences Raises $10M in Private Financing
NEW YORK (GenomeWeb News) – Cell Biosciences has raised $10 million through a Series C private financing, the Palo Alto, Calif.-based firm said today. (Thu, 09 Apr 2009 14:16:23 GMT)
Cell Biosciences raises $10M in 3rd round
Cell Biosciences Inc., a provider of nanoproteomic analysis systems to life science researchers, said Thursday it closed a third round of funding with $10 million. (Thu, 09 Apr 2009 14:21:28 GMT)
7th [BC]2 Basel Computational Biology Conference
( Swiss Institute of Bioinoformatics ) The seventh Basel Computational Biology Conference 2009 "Molecular Evolution" celebrates Charles Darwin's 200th birthday and the 150th anniversary of the publication of "On the Origin of Species." (Thu, 09 Apr 2009 14:48:37 GMT)
This Week in Nature
HHMI researcher Vivian Cheung led a study that looked at gene expression differences among people in response to exposure to radiation . In performing genetic linkage and association studies to map regulators of different gene expression phenotypes, the researchers found that for more than 1,200 of these, there was linkage to a specific chromosome region and that nearly all of the regulators are ... (Thu, 09 Apr 2009 16:01:13 GMT)
Final Results Year Ended 31 October 2008
ANTNANO PLC FINAL RESULTS FOR THE YEAR ENDED 31 OCTOBER 2008 AntNano Plc ("AntNano", or "the Company"), the specialist developer of highly-advanced equipment for detecting biochemicals and chemicals with applications in the industrial hygiene, medical and homeland security sectors, announces its Consolidated Annual Results for the year end 31 October 2008. Financial Highlights (compared to ... (Thu, 09 Apr 2009 16:07:52 GMT)
Products & Services
According to the company, the assays can be used to evaluate levels of RNA expression in model organisms including cows, chickens, horses, pigs, rabbits, and rice. (Thu, 09 Apr 2009 17:16:23 GMT)
Q&A: Johns Hopkins' Joshua Mendell on Global Activation of miRNA Biogenesis
Johns Hopkins researcher Joshua Mendell and colleagues have published new data showing that when a diversity of cell lines are grown to increasing density, microRNA biogenesis is globally activated, driving up levels of mature miRNAs and enhancing the suppression of their targets. (Thu, 09 Apr 2009 17:16:33 GMT)
Jury acquits US marine of Iraq detainee's murder
A military jury has acquitted a US marine sergeant on charges of murdering an unarmed detainee during battle in Fallujah, Iraq. The jury at Camp Pendleton, California, also acquitted Sergeant Ryan Weemer today of dereliction of duty in the November 2004 death. (Thu, 09 Apr 2009 17:38:32 GMT)
New Products
Also called protein transduction domains, the peptides are carriers with small peptide domains that can "freely cross cell membranes," the company said in a statement. Such functionality is needed to deliver the functional domain of a selected protein from the outside to the inside of intact cells. (Thu, 09 Apr 2009 18:01:15 GMT)
Recent Research Papers of Note
In previous work, authors determined that methanol-assisted solubilization facilitates the identification of both hydrophobic and hydrophilic membrane proteins compared to Brij-58 solubilization. The method was particularly effective for leucine-rich repeat receptor-like kinases, they said. (Thu, 09 Apr 2009 18:01:25 GMT)
Q&A: Mass Spec Study Says Nicotine May Affect Cell Interactions More Broadly Than Thought
The alpha-7 nicotinic acetylcholine receptor is an established high-affinity alpha bungarotoxin-binding protein in mammalian brain associated with learning and memory. (Thu, 09 Apr 2009 18:16:16 GMT)
Majority of Proteomic Stimulus Winners Not Likely to Buy Equipment, Analyst Report Finds
Proteomic tool vendors may not see much benefit from the $10.4 billion stimulus package passed by the US government in February, according to a report from an investment firm. (Thu, 09 Apr 2009 18:16:25 GMT)
Mo. Senate stalls again on tax-break legislation
Gridlock prevailed over compromise in the Missouri Senate early Thursday, resulting in another failed effort to pass job-creation incentives supported by Gov. Jay Nixon and legislative leaders. (Thu, 09 Apr 2009 18:24:56 GMT)
Fisher Scientific Inks Supply Deal with Mass Bio Council
NEW YORK (GenomeWeb News) – The Massachusetts Biotechnology Council has inked a five-year deal with Fisher Scientific to be the primary supplier for the MBC Purchasing Consortium. (Thu, 09 Apr 2009 18:31:13 GMT)
Golden Helix Hires Distributor for India
NEW YORK (GenomeWeb News) – Golden Helix said today that it has tapped Spinco Biotech to distribute its genetic analysis software in India. (Thu, 09 Apr 2009 18:31:34 GMT)
New funding allows UC Davis researchers to develop simple diagnostic test for kidney cancer
"We want to be able to find these tumors as early as possible by quickly screening for them in primary care clinics." (Fri, 10 Apr 2009 00:35:58 GMT)
One Year After Roche Acquisition, NimbleGen Forges Ahead with New Business Initiatives
One year after Roche acquired NimbleGen Systems — the same year that unfavorable market conditions drove Applied Biosystems, Nanogen, and GE Healthcare to abandon the array space — Roche NimbleGen continues to expand. (Fri, 10 Apr 2009 10:16:13 GMT)
Tailored to You
In this segment , NPR's Morning Edition discusses personalized medicine. (Fri, 10 Apr 2009 10:16:24 GMT)
Changing the Definition of Extinct
MD Anderson scientists have put the DNA of the extinct Tasmanian tiger back into transgenic mice to see how it would function, according to a paper published in PLoS ONE . Finding that thylacine Col2A1 enhancer directed chondrocyte-specific expression in the tiger the same way it does in mice, this is the first time that DNA from an extinct species has been used to examine function in a living ... (Fri, 10 Apr 2009 10:16:34 GMT)
Meanwhile, the Pricing Folks at Nature and Science Rejoice
Peter Suber, who spends his days thinking about open access issues, posted this entry on his blog -- it's an excerpt from a press release issued by Yale explaining its libraries' decision to stop supporting BioMed Central's Open Access publishing effort. (Fri, 10 Apr 2009 10:16:44 GMT)
Array Firms Scramble to Make New Chips As Sanger’s MicroRNA Database Expands
Within hours of the twelfth version of the miRBase database of published miRNA sequences and annotation going online Sept. 1, a host of array companies began pledging to update their miRNA offerings to reflect the most up-to-date content available. (Fri, 10 Apr 2009 10:46:13 GMT)
Opportunistic Investor's Moat Philosophy
Look for growing moats instead of wide moats. (Fri, 10 Apr 2009 11:00:00 GMT)
6th Annual World Congress Of IBMISPS To Be Co-Hosted By Elsevier And Brain Mapping Foundation
Elsevier, the world-leading publisher of scientific, technical and medical information products and services and Brain Mapping Foundation, has announced that it will Co-host the 6th Annual World Congress for Brain Mapping and Image Guided Therapy, August 26-29, 2009 at Harvard Medical School, Boston, USA. (Fri, 10 Apr 2009 11:15:42 GMT)
MDRNA, Inc. Complies With NASDAQ Marketplace Rule 4350(b)(1)(B)
MDRNA, Inc. announced today that the Company's independent registered public accounting firm included an explanatory paragraph in their opinion on the Company's financial statements included in the recently filed Annual Report on Form 10-K for the year ended December 31, 2008, relating to the Company's ability to continue as a going concern. (Fri, 10 Apr 2009 12:00:00 GMT)
MDRNA, Inc. Complies With NASDAQ Marketplace Rule 4350(b)(1)(B)
BOTHELL, WA--(Marketwire - April 10, 2009) - MDRNA, Inc. ( NASDAQ : MRNA ) announced today that the Company's independent registered public accounting firm included an explanatory paragraph in their opinion on the Company's financial statements included in the recently filed Annual Report on Form 10-K for the year ended December 31, 2008, relating to the Company's ability to continue as a going ... (Fri, 10 Apr 2009 12:07:48 GMT)
Cloud computing brings cost of protein research down to Earth
( Medical College of Wisconsin ) Medical College of Wisconsin researchers have developed a set of free tools called ViPDAC (virtual proteomics data analysis cluster), for use in combination with Amazon's inexpensive "cloud computing" service, providing the option to rent processing time on its powerful servers; and free software from the NIH and the University of Manitoba, to put this very ... (Fri, 10 Apr 2009 13:48:47 GMT)
NIH Outlines Stimulus Challenge Grants for Genomics
NEW YORK (GenomeWeb News) – Some of the $200 million in American Recovery and Reinvestment Act funding that has been marked for the National Institutes of Health's Challenge Grants program will go for research areas that generally come under the National Human Genome Research Institute's domain. (Fri, 10 Apr 2009 14:01:19 GMT)
Helicos Updates Filing for Selling Shareholders
NEW YORK (GenomeWeb News) – Helicos BioSciences has filed a new preliminary prospectus with the US Securities and Exchange Commission for the sale of around 9.6 million shares by shareholders of the firm. (Fri, 10 Apr 2009 14:01:30 GMT)
NIAID's HIV-1 Program Funds Genetics
NEW YORK (GenomeWeb News) – The National Institute of Allergy and Infectious Diseases will give grants to investigators who will use various methods to understand HIV-1 persistence in patients using anti-retroviral therapy, and to generate information that can be used to develop new assays or treatments. (Fri, 10 Apr 2009 14:01:44 GMT)
Beckman Coulter Buys Genomics Unit
Boston Business Journal | Clinical Data has sold its outsourced genomics division, Cogenics, to Beckman Coulter for $17 million. (Fri, 10 Apr 2009 15:24:10 GMT)
Economics of Personal Genomics
MSN Money | Would you pay $99,000 to know your past and your future? That's what Knome charges for full genetic mapping. (Fri, 10 Apr 2009 15:24:22 GMT)
Venture Capital on The Table
An opinion piece in the Wall Street Journal says venture capital firms don't need to be registered with the Securities and Exchange Commission as Treasury Secretary Timothy Geithner suggested. (Fri, 10 Apr 2009 15:46:17 GMT)
This Week in Science
A special section on protein dynamics presents several review articles exploring how protein-protein interactions and protein conformation relate to function. (Fri, 10 Apr 2009 16:01:13 GMT)
Just Keep Bidding
If you're feeling a bit low on funds to keep your lab running, try taking David Ng's approach . He was looking into whether a layman could set up a molecular biology lab -- and it appears to be fairly straightforward, if you use eBay: a microcentrifuge for $45.99, an agarose gel box for $99.99, or a PCR thermal cycler for $149.99. All in all, Ng finds it would take less than $1,000 to get much ... (Fri, 10 Apr 2009 16:01:30 GMT)
Like the Kevin Bacon Game, But More Depressing
With all the people, foundations, and their beneficiaries (PDF file) that have lost money to Bernard Madoff's Ponzi scheme, John Fossella at Genes to Brains to Mental Health wondered what his institution's exposure was . Using a relationship tracking tool from Muckety , Fossella found one connection between Mount Sinai School of Medicine and Madoff, a person who is a trustee and patron for both ... (Fri, 10 Apr 2009 16:01:33 GMT)
Cloud computing brings cost of protein research down to Earth
Researchers at the Medical College of Wisconsin Biotechnology and Bioengineering Center in Milwaukee have just made the very expensive and promising area of protein research more accessible to scientists worldwide. (Fri, 10 Apr 2009 16:11:24 GMT)
UC Santa Cruz team creates tool to view cancer research data
SANTA CRUZ -- Researchers at UC Santa Cruz have created a browser that provides a new way of seeing and studying data from some cancer studies. (Fri, 10 Apr 2009 16:13:35 GMT)
Collaboration Leads to Success: Most Powerful Computer of its Kind in WNY Available World-Wide
Local scientist Dr. Russ Miller is leading the rollout of "Magic," one of the most powerful computers in New York State to qualified users worldwide for solving computationally-demanding problems. (Fri, 10 Apr 2009 18:02:00 GMT)
People in the News
NEW YORK (GenomeWeb News) - Navigenics has appointed Jack Lord to take over the office of president and CEO, which was vacated by Mari Baker , who has taken the CEO job at PlayFirst. Lord was chief innovation officer at Humana, and before that he was president of Health Dialog. (Fri, 10 Apr 2009 18:16:52 GMT)
In Brief This Week: 454 Life Sciences; BioReference Laboratories; Sidmap; IDBS; GeneNews; and More
NEW YORK (GenomeWeb News) – Roche said this week that a paper published in the most recent issue of the Journal of Infectious Disease demonstrated that ultra-deep sequencing with 454 Life Sciences' sequencing system was able to identify low-frequency hepatitis B virus drug-resistant mutations in infected samples, including mutations that were undetected using standard direct PCR sequencing ... (Fri, 10 Apr 2009 18:31:13 GMT)
Complete Genomics Cuts Wages, Other Costs as Financing Round is Delayed
NEW YORK (GenomeWeb News) - In response to a delay in the closing of its Series D financing round, Complete Genomics has cut its costs, including staff salaries, GenomeWeb Daily News sister publication In Sequence reported today. (Fri, 10 Apr 2009 19:01:13 GMT)
Bioinformatics Briefs
Dana-Farber Cancer Institute said this week that it is opening a Center for Cancer Computational Biology that will offer researchers access to data-analysis and -interpretation services. (Fri, 10 Apr 2009 19:01:24 GMT)
Downloads & Upgrades
BioDiscovery has launched Nexus Copy Number Version 4 , a platform-independent application for DNA copy-number analysis of microarray-derived data. (Fri, 10 Apr 2009 19:01:34 GMT)
People in the News
The annual award is given to a scientist "who epitomizes the open-source values" espoused by Benjamin Franklin, Bioinformatics.Org said in a statement. Bourne will be presented with the award at the 2009 Bio-IT World Conference & Expo in Boston on April 28. (Fri, 10 Apr 2009 19:01:44 GMT)
Funding Update
Yao and his team are focused on investigating the plasma membrane expression of CFTR, the critical gene linked to cystic fibrosis, using a specially designed mass spec assay developed through a partnership with the Cystic Fibrosis Foundation. (Fri, 10 Apr 2009 19:16:14 GMT)
Complete Genomics Cuts Wages, Other Costs as it Seeks to Close Series D Financing Round
In response to a delay in the closing of its Series D financing round, Complete Genomics has cut its costs, including staff salaries, In Sequence has learned. (Fri, 10 Apr 2009 19:31:13 GMT)
US Gov't Stimulus Package Could Be 'Boon' for Bioinformatics, NIH Officials Say
The US stimulus package has created numerous opportunities for bioinformaticists — through dedicated award opportunities as well as supporting capabilities on non-computational programs. (Fri, 10 Apr 2009 20:31:23 GMT)
India's Persistent Systems Hopes Deal With Indiana U Will Bolster Its Bioinformatics Services
Persistent Systems, an IT services firm headquartered in Pune, India, is partnering with Indiana University's School of Informatics to ramp up its life sciences domain expertise. (Fri, 10 Apr 2009 20:31:31 GMT)
Stanford Students Start Consultancy to Help Stimulus Recipients Fulfill Bioinformatics Needs
Looking to capitalize on new grants that the National Institutes of Health is offering through the American Recovery and Reinvestment Act, a group of Stanford University PhD students has started a consulting company to help wet-lab biologists with the bioinformatics component of new projects. (Fri, 10 Apr 2009 20:31:41 GMT)
B vitamins may offer migraine relief
Daily vitamin supplements were found to produce a two-fold reduction in migraine disability, according to scientists from the Genomics Research Centre (GRC) at Griffith University in Brisbane. (Fri, 10 Apr 2009 21:24:09 GMT)
U.S. medical industry a long way from being paperless
Modernizing the nation's health records has become a big push of the Obama administration, with $19 billion tucked into the $787 billion stimulus package to help hospitals and doctors digitize paper charts and stem the skyrocketing cost of health care nationwide. (Sat, 11 Apr 2009 05:23:44 GMT)
University Of Michigan Installs Second Genomatix Genome Analyzer
Genomatix Software, a leading provider of complete solutions for the analysis of Next Generation Sequencing (NGS) data, has announced that the CCDU Bioinformatics Core of the Center for Computational Medicine and Biology at the University of Michigan installed a Genomatix Genome Analyzer (GGA) at its labs in Ann Arbor, MI. (Sat, 11 Apr 2009 10:15:34 GMT)
Because We're Nothing Without a Sense of Humor
Ever wonder what you could do with your genome (besides sequencing it, that is)? Here's a blog post of " 10 amusing things to do with your genome " from Nivair Gabriel at io9. (Sat, 11 Apr 2009 10:16:20 GMT)
You Don't Often Hear the Pro-Obesity Health Argument
According to this wire story , scientists in Norway homed in on epigenetic markers that indicate which stem cells are best suited for regenerating tissue. The catch? The work has been performed on liposuctioned stem cells. (Sat, 11 Apr 2009 10:16:42 GMT)
The Master of One Will Be the Master of Many
At Discovering Biology in a Digital World, Sandra Porter discusses what software biology students should be learning. (Sat, 11 Apr 2009 10:16:53 GMT)
What a 'Previvor' Learned from Her Genome
The New York Times book reviews this weekend covers Blood Matters , a book by Moscow-based journalist Masha Gessen, who describes her experiences and the effect on her family of testing positive for the BRCA1 mutation . The Times calls the book very funny and liberating, and concludes that "it's also very lucid, even when the science gets complex." (Sat, 11 Apr 2009 10:17:02 GMT)
Conference To Promote Cancer Awareness For Vast Navajo Nation
Outreach efforts by the Translational Genomics Research Institute (TGen) extend to the far corners of Arizona. For the second year, TGen will help organize a cancer awareness conference for northeastern Arizona's vast Navajo Nation. The 2nd annual Fort Defiance Cancer Awareness and Advocacy Conference, sponsored by the Arizona Myeloma Network, is planned 8:30 a.m.-5 p.m. (Sat, 11 Apr 2009 11:14:32 GMT)
University Of Cincinnati Receives $22.7 Million To Launch New Center
The National Institutes of Health has announced that the University of Cincinnati will become the 39th member of its Clinical and Translational Science Award (CTSA) consortium. (Sat, 11 Apr 2009 11:14:41 GMT)
Connecting the Dots of Medicine and Data
The push for electronic health records is causing demand to surge for health informatics specialists. (Sat, 11 Apr 2009 23:24:38 GMT)
COMMENTARY: No, future is in European style club sports system
The dye has been cast. The days of American Exceptionalism are numbered. (Sun, 12 Apr 2009 09:43:55 GMT)
Looks Like We Can't Sweep That Under the Rug
The BBC reports on a paper published in the American Journal of Human Genetics in which scientists from the Genographic Project report finding faint DNA traces "left by medieval crusaders in the Middle East," according to the article. (Sun, 12 Apr 2009 10:31:13 GMT)
As Long as It Supports Your Conclusions
DrugMonkey is continuing on the NIH grant primer series with a revised edition on how to update your grant application -- if you do an update, make it count and have it show your commitment to the project, especially if you've submitted a relevant paper. (Sun, 12 Apr 2009 10:31:43 GMT)
The Data Is Your Palette
While powerful compute muscle in the form of workstations, acceleration hardware, and sophisticated algorithms continues to help crunch data sets that seem to multiply at turbo-charged rates, it isn't becoming any easier for researchers to make sense of it all. (Sun, 12 Apr 2009 10:46:14 GMT)
Mo. Senate vows to try again on tax-break bill
Compromise has failed. So has a grueling late-night Senate session designed to wait out the opposition. (Sun, 12 Apr 2009 11:34:23 GMT)
Locking Parasites In Host Cell Could Be New Way To Fight Malaria
Researchers have discovered that parasites hijack host-cell proteins to ensure their survival and proliferation, suggesting new ways to control the diseases they cause. (Sun, 12 Apr 2009 15:28:11 GMT)
Palm genome institute to help sector raise productivity (Business Times
MALAYSIA will set up a research facility in Bangi, Selangor, to help boost the oil palm industry's productivity through a better understanding of the plant's genetic code. (Sun, 12 Apr 2009 18:57:26 GMT)
Halcyon Molecular, Caliper Life Sciences, NHGRI, RainDance Technologies, National Center for Genome Resources, SAS, ...
Startup firm Halcyon Molecular is working on an electron microscopy-based DNA sequencing technology, In Sequence has learned. (Mon, 13 Apr 2009 00:46:13 GMT)
Indian festival colors campus
Divya Sinha (senior-pre-medicine), right, gives Ravi Heerwani (senior-supply chain and information systems) his first touch of color during Holi. (Mon, 13 Apr 2009 09:09:44 GMT)
COMMENTARY: No, future is in European style club sports system
The dye has been cast. The days of American Exceptionalism are numbered. (Mon, 13 Apr 2009 09:43:55 GMT)
Connecting the Dots of Medicine and Data
The push for electronic health records is causing demand to surge for "health informatics specialists." (Mon, 13 Apr 2009 10:19:44 GMT)
Time to Keep a Closer Eye on Fifi
Soon there'll be a DNA database for anything you can imagine. Today's entry: an Israeli city near Tel Aviv is "setting up a special DNA database of local dogs," according to this BBC story . "They will use the data to match dogs' droppings to owners - and punish those who do not clean up after their pets." (Mon, 13 Apr 2009 10:31:13 GMT)
At 17, We Were Worried About Our Prom Dates
Seventeen-year-old Shivani Sud, from North Carolina, won the Intel Science Talent Search and its $100,000 scholarship, according to an article in the Boston Globe . Using information publicly available (which included clinical samples), Sud identified genetic markers that predict recurrence of stage II colon cancer. (Mon, 13 Apr 2009 10:31:23 GMT)
And That's Why They Call It Evolution
The Darwin Awards have been announced for 2006. These awards, begun in 1993, "salute the improvement of the human genome by honoring those who accidentally remove themselves from it, thus ensuring that the next generation is one idiot smarter." (Mon, 13 Apr 2009 10:31:43 GMT)
Prometheus and Rosetta Genomics Announce License and Collaboration Agreement
based Molecular Diagnostics to Mark Prometheus' Entry into Oncology Market; Rosetta to Receive Milestones and Research and Development Funding plus Future Royalties (Mon, 13 Apr 2009 11:00:00 GMT)
Signature Genomic Laboratories Announces Appointment of New Laboratory Director
SPOKANE, Wash.----Signature Genomic Laboratories has appointed Trilochan Sahoo, M.D., as a Laboratory Director. (Mon, 13 Apr 2009 13:08:00 GMT)
City's 'shocking' gender pay gap revealed in equality report
Women working full-time in the financial sector earn 55% less a year on average than their male counterparts, with those in some of the most lucrative areas, such as fund management and futures trading, suffering the greatest disparities, according to research published today. The report from the Equality and Human Rights Commission (EHRC) also contains further evidence that women struggle to ... (Mon, 13 Apr 2009 13:20:49 GMT)
Verdezyne to Optimize Genes for Novozymes
NEW YORK (GenomeWeb News) – Verdezyne said that it will optimize selected genes that encode industrial enzymes for Novozymes, under a contract announced today. (Mon, 13 Apr 2009 14:31:15 GMT)
Nanobac Pharmaceuticals and Eureka Genomics Sign Merger Agreement
Nanobac Pharmaceuticals, Inc. (Pinksheets: NNBP) and privately held Eureka Genomics announced the signing of a definitive merger agreement, which delineates the terms and conditions under which Nanobac proposes to merge with Eureka in a stock and cash transaction. (Mon, 13 Apr 2009 14:42:00 GMT)
Prometheus to Sell Rosetta Genomics' Tests; Takes Equity Stake
NEW YORK (GenomeWeb News) – Prometheus Laboratories has licensed US rights to Rosetta Genomics' recently introduced microRNA-based tests and has taken an equity stake in the molecular diagnostics firm. (Mon, 13 Apr 2009 14:46:13 GMT)
This Week in PLoS
In PLoS Biology , lead author Nikolay Ninov from the Instituto de Biología Molecular de Barcelona reports on a study of cell cycle and growth in Drosophila abdominal cells. (Mon, 13 Apr 2009 14:46:33 GMT)
Nanobac Pharmaceuticals and Eureka Genomics Sign Merger Agreement
Merger Will Create OTC-Pink Sheets-Listed Company Driving the Evolution of Next-Generation Genomics and Bioinformatics (Mon, 13 Apr 2009 14:53:02 GMT)
Movers & Shakers: Monday's biggest gaining and losing stocks
Among the companies whose shares made notable moves in the stock market Monday are Citigroup Inc., General Motors Corp., Express Scripts Inc. and Seagate Technology Inc. (Mon, 13 Apr 2009 15:42:23 GMT)
Rosetta Grants Prometheus Rights to Sell Suite of microRNA Diagnostics in US
Rosetta Genomics today announced that it has granted the right to sell its three microRNA-based diagnostics in the US to drug and diagnostic firm Prometheus Laboratories. (Mon, 13 Apr 2009 15:46:14 GMT)
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