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Bioinformatics News 03/2009 (Page 4)

Funding Update (GenomeWeb News)
The investigators recently demonstrated a "correlation between kinetic stability and a protein's resistance to the detergent sodium dodecyl sulfate" according to the abstract, and developed a simple diagonal 2D SDS-polyacrylamide gel electrophoresis method for the identification of kinetically stable proteins in complex mixtures.

Science or Snake Oil? (GenomeWeb News)
There has long been a sort of parallel industry trying to capitalize on genomic advances — companies that promise to find your perfect mate through DNA matching, and other services of dubious quality. (Remember genetically tailored, personalized skin creams?)

LabVantage, Waters Integrate Software (GenomeWeb News)
NEW YORK (GenomeWeb News) – Waters and LabVantage Solutions have partnered to integrate lab and data management software platforms, the firms said today.

NHLBI Set to Start Third Major Proteomics Program (GenomeWeb News)
With its two major proteomics programs winding down, the National Heart Lung and Blood Institute is embarking on its next major program, which calls for researchers to develop proteomics technologies and apply them to solve clinical puzzles.

Foundation Working with NCGR on Multiplex Genetic Test for Rare Diseases (GenomeWeb News)
NEW YORK (GenomeWeb News) – a newly formed foundation said this week that it is working with researchers at the National Center for Genome Resources on a multiplex test for rare genetic diseases.

Venter, Somerville and Church highlight DOE/JGI genomics of energy and environment meeting (EurekAlert!)
( DOE/Joint Genome Institute ) Keynote addresses by genomics pioneers J. Craig Venter, Energy Bioscience Institute's Chris Somerville and Harvard's George Church will highlight the US Department of Energy Joint Genome Institute annual Genomics of Energy and Environment User Meeting March 25-27, 2009, in Walnut Creek, Calif.

Working Well With Others (GenomeWeb News)
In response to a post at Nature 's Nautilus that scoffs at papers with more than 20 contributing authors , blogger RPM points out that some disciplines need a lot of people to complete a project.

The Follow-On to the Follow-On to the Follow-On to 23andMe (GenomeWeb News)
Family Tree DNA is now offering DNATraits , a personal genomics service that specializes in DNA testing for specific diseases, says The Genetic Genealogist . The company offers individual tests, group tests, and even a membership plan, all for relatively cheap prices compared to the other companies offering genome-wide SNP scans.

Here's an Idea: Stop Looking for Cancer and You Won't Find Any (GenomeWeb News)
In this opinion piece that ran in the Washington Post , physicians write that the goal in testing for cancer shouldn't be finding all cases, but rather finding those particular cases that need treatment. "The goal is not to find more cancer. The goal is to save lives.

He'll Always Be the SARS Guy to Us (GenomeWeb News)
Jonathan Eisen has a blog post congratulating UCSF's Joe DeRisi on winning the Heinz Award -- and, since it's Eisen, reminding us that DeRisi is " one of the true pioneers of Open Science , not only promoting Open Access publishing but also promoting open sharing of methods, equipment, data, and everything."

Candidate Deeds to visit Blue Mountain Coffee (The Staunton News Leader)
STAUNTON — As the June 9 primary clock ticks down, Democratic Party gubernatorial-nomination candidate Creigh Deeds will arrive for a noon meeting today at the Blue Mountain Coffee at 12 Byers St. in downtown Staunton.

CombiMatrix to Present At Invest Northwest 2009 Conference (GlobeNewswire via Yahoo! Finance)
MUKILTEO, Wash., March 6, 2009 -- CombiMatrix Corporation today announced Dr. Amit Kumar, President and CEO, will present at the Invest Northwest 2009 Conference on March 18, 2009, at 10:10 a.m. , in the Bay Auditorium at the Bell Harbor International Conference Center located in Seattle, Washington.

Transgenomic Gets California OK for Clinical Lab (GenomeWeb News)
NEW YORK (GenomeWeb News) – California health officials have cleared Transgenomic to offer its molecular lab services in the state by certifying its lab, the company said today.

BioFocus' 2008 Revenues Increase 16 Percent (GenomeWeb News)
NEW YORK (GenomeWeb News) – BioFocus DPI, the drug discovery products and services division of Belgian firm Galapagos, brought in revenues of €56.4 million ($71.7 million) for full-year 2008, the firm announced today.

NIGMS Offers $3M for PGx Knowledge Base (GenomeWeb News)
NEW YORK (GenomeWeb News) – The National Institute of General Medical Sciences will grant up to $3 million this year to fund one pharmacogenomics knowledge resource that will "serve the needs of the entire research community" through a National Institutes of Health funding opportunity.

Getting Them to Stick (GenomeWeb News)
Derek Lowe tosses around some ideas for using small molecules as binding partners for immobilizing proteins to solid supports like beads and chips. Affinity chromatography is one way; surface plasmon resonance, which can tell with great sensitivity if something is sticking close to a solid surface , is another current approach that's making headway.

Social Networking for Personal Health Records (GenomeWeb News)
At Life as a Healthcare CIO, John Halamka reports that yesterday, Google Health launched a "social networking" feature for its personal health records.

British Teenage Scientists Are Not Boring Geeks (GenomeWeb News)
According to a story in the BBC, winners of the first national science competition for young scientists in the UK were selected.

Going to the Extreme (GenomeWeb News)
In work published in Applied and Environmental Microbiology , scientists found extremophiles -- photoautotrophic microbial communities -- in the Atacama desert in Chile, the driest place on Earth and also the place that most resembles the conditions on Mars. If life could be found to exist here, the authors suppose, it could be found on Mars, too.

This Week in Science (GenomeWeb News)
The speed with which funds from the stimulus package are given out by the NIH or NSF won't comprise the quality of the research , reports Science . To get the money out the door quickly and into researchers' hands, the funding agencies will look to the existing applicant pool and NIH is also soliciting for two-year challenge grants with an application deadline in late April.

Young Investigator Profile (GenomeWeb News)
454 Life Sciences has hired Mort Minaee as head of regulatory affairs. Minaee joins the firm from Abbott Molecular Diagnostics , where he was director of regulatory and clinical affairs.

In Print (GenomeWeb News)
Ackermann M, Strimmer K. A general modular framework for gene-set enrichment analysis . [ BMC Bioinformatics 2009, 10:47]: The authors conducted an "extensive survey" of statistical approaches for gene-set enrichment analysis and identified "a common modular structure underlying most published methods."

Bioinformatics Briefs (GenomeWeb News)
The National Institute of General Medical Sciences said this week that it will grant up to $3 million this year to fund a pharmacogenomics knowledge resource that will "serve the needs of the entire research community."

Downloads and Upgrades (GenomeWeb News)
Premier Biosoft International has released a new version of its AlleleID software. AlleleID 7.01 assists qPCR and microarray users in designing species-specific and targeted primers and probes.

Young Investigator Profile (GenomeWeb News)
Julius Brennecke is studying small RNA pathways in Drosophila using DNA sequencing technologies, genetics, bioinformatics, and cell biology.

Penn vet researchers identify a critical growth factor that stimulates sperm stem cells to thrive (EurekAlert!)
( University of Pennsylvania ) Researchers at the University of Pennsylvania School of Veterinary Medicine and Pennsylvania State University have identified for the first time a specific "niche factor" in the mouse testes called colony stimulating factor 1, Csf1, that has a direct effect on sperm stem cell self-renewal.

UBC's New Middleware Turns Web Service Output into Semantic Web Resource (GenomeWeb News)
Building on experience gained from the open source BioMoby interoperability framework, researchers at the University of British Columbia have created a new middleware platform called SADI, or Semantic Automated Discovery and Integration , which blends web services and semantic web technology to help researchers integrate disparate data resources.

UK's Epistem Inks Two-Year Stem-Cell Drug-Discovery Collaboration With Novartis (GenomeWeb News)
Epistem, a Manchester, UK -based epithelial stem cell vendor, announced this week that it has entered into a research and development collaboration with Novartis to identify drugs and drug targets across a range of undisclosed disease areas.

Tech professor under state auditor inquiry (WSLS Newschannel 10 Roanoke)
A state auditor said Friday former Virginia Bioinformatics Institute Director Bruno Sobral has been under review for at least the past three months. Sobral is still a researcher and professor employed at Virginia Tech.

Penn vet researchers identify a critical growth factor that stimulates sperm stem cells to thrive (PhysOrg)
Researchers at the University of Pennsylvania School of Veterinary Medicine and Pennsylvania State University have identified for the first time a specific "niche factor" in the mouse testes called colony stimulating factor 1, Csf1, that has a direct effect on sperm stem cell self-renewal. Moreover, the study shows that the origin of this growth factor is the Leydig cell - located in the testes ...

Better Sequence Searches Of Genes And Proteins Devised (Science Daily)
Often, the sequences of genes and proteins can suggest to us what their function is -- especially if we compare them with known sequences. Researchers have now developed a method that makes such analyses significantly more sensitive.

On Sale Now: Ethics (GenomeWeb News)
The New York Times reports that Virginia Commonwealth University signed a deal with Philip Morris that prevents professors from publishing or discussing their research without the tobacco giant's permission -- contrary to the school's own rules.

Linnaeus, Meet the Web (GenomeWeb News)
Announcing their plans in May to build an online Encyclopedia of Life , evolutionary biologists hope to create a comprehensive, online catalog of the genome and phylogeny of all known species on the planet.

Here in the US, It's Politics Aplenty (GenomeWeb News)
We're aflutter with politics today. First, people are flocking to ScienceDebate2008, a group attempting to get clear stances from political candidates about their scientific views. Barack Obama stepped up and answered the group's 14 questions (John McCain has said he will answer them too).

In This Case, Being Lucky Takes a Whole Lot of Work (GenomeWeb News)
Northwestern University's Richard Silverman and his work leading to the discovery and marketing of Pfizer's blockbuster, Lyrica, are profiled in this Chicago Tribune article.

Fumes From SJ Biochemical Firm Hospitalize Three (KTVU 2 San Francisco)
SAN JOSE, Calif. -- A biochemical firm was shut down Friday by San Jose firefighters after fumes from a chemical leak sent two inspectors and a facility employee to the hospital, a fire captain said.

Beats, Booze and Brains: Where Nerds Party (ABC News)
Club for fun-loving nerds aims to make science cool in the Big Apple.

Fumes From SJ Biochemical Firm Hospitalize Three (FOX 11 Reno)
SAN JOSE, Calif. -- A biochemical firm was shut down Friday by San Jose firefighters after fumes from a chemical leak sent two inspectors and a facility employee to the hospital, a fire captain said.

Be indispensable: Skills to beat the recession (National Post)
It's going to be a very different world out there. Here are some hints for preparing for it.

Be indispensable: Skills to beat the recession (National Post)
It's going to be a very different world out there. Here are some hints for preparing for it.

Harvard Scientists’ Discovery Opens Door to Synthetic Life (Bloomberg)
March 7 (Bloomberg) -- Harvard University scientists are a step closer to creating synthetic forms of life, part of a drive to design man-made organisms that may one day be used to help produce new fuels and create biotechnology drugs.

Lab Cartoon (GenomeWeb News)
Julius Brennecke is studying small RNA pathways in Drosophila using DNA sequencing technologies, genetics, bioinformatics, and cell biology.

Pacific Biosciences, Beijing Genomics Institute Shenzhen, Fluidigm, Stanford University, Sequenom, Chinese University ... (GenomeWeb News)
Menlo Park, Calif.-based Pacific Biosciences said two weeks ago that it recently received $20 million in funding from new investor Blackstone Cleantech Venture Partners.

Welcome to Your 15 Minutes (GenomeWeb News)
Over at Buzzyeah, Andrew Meyer blogs about his weekend stint being interviewed on a radio show about genetic testing. The segment also included a VP from DNA Direct, says Meyers, who recently got his genome results from 23andMe.

On This Slide, You See... (GenomeWeb News)
We've all been there, at a conference where the speakers use so much text on their slides that it is barely legible — not that you have enough time to read it because the moderator didn't really moderate and the speaker has to fly through his talk.

Pledge from Obama ignites new hope among cancer researchers, survivors (Pioneer Press)
CHICAGO — Echoing the words of former President Richard Nixon almost 40 years earlier, President Barack Obama in his speech to Congress last month expressed his commitment to launching an effort to find "a cure for cancer in our time."

Pledge from Obama ignites new hope among cancer researchers, survivors (Pioneer Press)
CHICAGO — Echoing the words of former President Richard Nixon almost 40 years earlier, President Barack Obama in his speech to Congress last month expressed his commitment to launching an effort to find "a cure for cancer in our time."

Be indispensable: Skills to beat the recession (National Post)
It's going to be a very different world out there. Here are some hints for preparing for it.

Be indispensable: Skills to beat the recession (National Post)
It's going to be a very different world out there. Here are some hints for preparing for it.

Shanghai Team Analyzes Mechanism That Enables Adult Cells To Behave Like Embryonic Stem Cells (Medical News Today)
Agilent Technologies Inc. (NYSE:A) today announced its collaboration with a team from the Shanghai Institutes for Biological Sciences and Tongi University that has achieved new insight into how adult cells can be induced to act like embryonic stem cells (ESC), with the ability to form any type of tissue known as "pluripotency.


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