Bioinformatics News Mar 2009: bioinformatics, genomics, proteomics, microarray, etc.

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Funding Update
The investigators recently demonstrated a "correlation between kinetic stability and a protein's resistance to the detergent sodium dodecyl sulfate" according to the abstract, and developed a simple diagonal 2D SDS-polyacrylamide gel electrophoresis method for the identification of kinetically stable proteins in complex mixtures. (Thu, 05 Mar 2009 19:53:29 GMT)

Science or Snake Oil?
There has long been a sort of parallel industry trying to capitalize on genomic advances — companies that promise to find your perfect mate through DNA matching, and other services of dubious quality. (Remember genetically tailored, personalized skin creams?) (Thu, 05 Mar 2009 20:08:19 GMT)

LabVantage, Waters Integrate Software
NEW YORK (GenomeWeb News) – Waters and LabVantage Solutions have partnered to integrate lab and data management software platforms, the firms said today. (Thu, 05 Mar 2009 20:23:53 GMT)

NHLBI Set to Start Third Major Proteomics Program
With its two major proteomics programs winding down, the National Heart Lung and Blood Institute is embarking on its next major program, which calls for researchers to develop proteomics technologies and apply them to solve clinical puzzles. (Thu, 05 Mar 2009 20:38:09 GMT)

Foundation Working with NCGR on Multiplex Genetic Test for Rare Diseases
NEW YORK (GenomeWeb News) – a newly formed foundation said this week that it is working with researchers at the National Center for Genome Resources on a multiplex test for rare genetic diseases. (Thu, 05 Mar 2009 20:53:10 GMT)

Venter, Somerville and Church highlight DOE/JGI genomics of energy and environment meeting
( DOE/Joint Genome Institute ) Keynote addresses by genomics pioneers J. Craig Venter, Energy Bioscience Institute's Chris Somerville and Harvard's George Church will highlight the US Department of Energy Joint Genome Institute annual Genomics of Energy and Environment User Meeting March 25-27, 2009, in Walnut Creek, Calif. (Thu, 05 Mar 2009 21:23:26 GMT)

Working Well With Others
In response to a post at Nature 's Nautilus that scoffs at papers with more than 20 contributing authors , blogger RPM points out that some disciplines need a lot of people to complete a project. (Fri, 06 Mar 2009 03:23:09 GMT)

The Follow-On to the Follow-On to the Follow-On to 23andMe
Family Tree DNA is now offering DNATraits , a personal genomics service that specializes in DNA testing for specific diseases, says The Genetic Genealogist . The company offers individual tests, group tests, and even a membership plan, all for relatively cheap prices compared to the other companies offering genome-wide SNP scans. (Fri, 06 Mar 2009 03:23:19 GMT)

Here's an Idea: Stop Looking for Cancer and You Won't Find Any
In this opinion piece that ran in the Washington Post , physicians write that the goal in testing for cancer shouldn't be finding all cases, but rather finding those particular cases that need treatment. "The goal is not to find more cancer. The goal is to save lives. (Fri, 06 Mar 2009 03:23:36 GMT)

He'll Always Be the SARS Guy to Us
Jonathan Eisen has a blog post congratulating UCSF's Joe DeRisi on winning the Heinz Award -- and, since it's Eisen, reminding us that DeRisi is " one of the true pioneers of Open Science , not only promoting Open Access publishing but also promoting open sharing of methods, equipment, data, and everything." (Fri, 06 Mar 2009 03:23:39 GMT)

Candidate Deeds to visit Blue Mountain Coffee
STAUNTON — As the June 9 primary clock ticks down, Democratic Party gubernatorial-nomination candidate Creigh Deeds will arrive for a noon meeting today at the Blue Mountain Coffee at 12 Byers St. in downtown Staunton. (Fri, 06 Mar 2009 08:30:41 GMT)

CombiMatrix to Present At Invest Northwest 2009 Conference
MUKILTEO, Wash., March 6, 2009 -- CombiMatrix Corporation today announced Dr. Amit Kumar, President and CEO, will present at the Invest Northwest 2009 Conference on March 18, 2009, at 10:10 a.m. , in the Bay Auditorium at the Bell Harbor International Conference Center located in Seattle, Washington. (Fri, 06 Mar 2009 11:00:00 GMT)

Transgenomic Gets California OK for Clinical Lab
NEW YORK (GenomeWeb News) – California health officials have cleared Transgenomic to offer its molecular lab services in the state by certifying its lab, the company said today. (Fri, 06 Mar 2009 15:38:08 GMT)

BioFocus' 2008 Revenues Increase 16 Percent
NEW YORK (GenomeWeb News) – BioFocus DPI, the drug discovery products and services division of Belgian firm Galapagos, brought in revenues of €56.4 million ($71.7 million) for full-year 2008, the firm announced today. (Fri, 06 Mar 2009 15:38:19 GMT)

NIGMS Offers $3M for PGx Knowledge Base
NEW YORK (GenomeWeb News) – The National Institute of General Medical Sciences will grant up to $3 million this year to fund one pharmacogenomics knowledge resource that will "serve the needs of the entire research community" through a National Institutes of Health funding opportunity. (Fri, 06 Mar 2009 15:53:09 GMT)

Getting Them to Stick
Derek Lowe tosses around some ideas for using small molecules as binding partners for immobilizing proteins to solid supports like beads and chips. Affinity chromatography is one way; surface plasmon resonance, which can tell with great sensitivity if something is sticking close to a solid surface , is another current approach that's making headway. (Fri, 06 Mar 2009 17:08:13 GMT)

Social Networking for Personal Health Records
At Life as a Healthcare CIO, John Halamka reports that yesterday, Google Health launched a "social networking" feature for its personal health records. (Fri, 06 Mar 2009 17:08:24 GMT)

British Teenage Scientists Are Not Boring Geeks
According to a story in the BBC, winners of the first national science competition for young scientists in the UK were selected. (Fri, 06 Mar 2009 17:08:34 GMT)

Going to the Extreme
In work published in Applied and Environmental Microbiology , scientists found extremophiles -- photoautotrophic microbial communities -- in the Atacama desert in Chile, the driest place on Earth and also the place that most resembles the conditions on Mars. If life could be found to exist here, the authors suppose, it could be found on Mars, too. (Fri, 06 Mar 2009 17:08:43 GMT)

This Week in Science
The speed with which funds from the stimulus package are given out by the NIH or NSF won't comprise the quality of the research , reports Science . To get the money out the door quickly and into researchers' hands, the funding agencies will look to the existing applicant pool and NIH is also soliciting for two-year challenge grants with an application deadline in late April. (Fri, 06 Mar 2009 18:38:09 GMT)

Young Investigator Profile
454 Life Sciences has hired Mort Minaee as head of regulatory affairs. Minaee joins the firm from Abbott Molecular Diagnostics , where he was director of regulatory and clinical affairs. (Fri, 06 Mar 2009 21:23:38 GMT)

In Print
Ackermann M, Strimmer K. A general modular framework for gene-set enrichment analysis . [ BMC Bioinformatics 2009, 10:47]: The authors conducted an "extensive survey" of statistical approaches for gene-set enrichment analysis and identified "a common modular structure underlying most published methods." (Fri, 06 Mar 2009 21:38:09 GMT)

Bioinformatics Briefs
The National Institute of General Medical Sciences said this week that it will grant up to $3 million this year to fund a pharmacogenomics knowledge resource that will "serve the needs of the entire research community." (Fri, 06 Mar 2009 21:38:19 GMT)

Downloads and Upgrades
Premier Biosoft International has released a new version of its AlleleID software. AlleleID 7.01 assists qPCR and microarray users in designing species-specific and targeted primers and probes. (Fri, 06 Mar 2009 21:38:29 GMT)

Young Investigator Profile
Julius Brennecke is studying small RNA pathways in Drosophila using DNA sequencing technologies, genetics, bioinformatics, and cell biology. (Fri, 06 Mar 2009 21:38:39 GMT)

Penn vet researchers identify a critical growth factor that stimulates sperm stem cells to thrive
( University of Pennsylvania ) Researchers at the University of Pennsylvania School of Veterinary Medicine and Pennsylvania State University have identified for the first time a specific "niche factor" in the mouse testes called colony stimulating factor 1, Csf1, that has a direct effect on sperm stem cell self-renewal. (Fri, 06 Mar 2009 21:41:15 GMT)

UBC's New Middleware Turns Web Service Output into Semantic Web Resource
Building on experience gained from the open source BioMoby interoperability framework, researchers at the University of British Columbia have created a new middleware platform called SADI, or Semantic Automated Discovery and Integration , which blends web services and semantic web technology to help researchers integrate disparate data resources. (Fri, 06 Mar 2009 21:53:09 GMT)

UK's Epistem Inks Two-Year Stem-Cell Drug-Discovery Collaboration With Novartis
Epistem, a Manchester, UK -based epithelial stem cell vendor, announced this week that it has entered into a research and development collaboration with Novartis to identify drugs and drug targets across a range of undisclosed disease areas. (Fri, 06 Mar 2009 22:23:29 GMT)

Tech professor under state auditor inquiry
A state auditor said Friday former Virginia Bioinformatics Institute Director Bruno Sobral has been under review for at least the past three months. Sobral is still a researcher and professor employed at Virginia Tech. (Fri, 06 Mar 2009 23:21:03 GMT)

Penn vet researchers identify a critical growth factor that stimulates sperm stem cells to thrive
Researchers at the University of Pennsylvania School of Veterinary Medicine and Pennsylvania State University have identified for the first time a specific "niche factor" in the mouse testes called colony stimulating factor 1, Csf1, that has a direct effect on sperm stem cell self-renewal. Moreover, the study shows that the origin of this growth factor is the Leydig cell - located in the testes ... (Sat, 07 Mar 2009 00:20:26 GMT)

Better Sequence Searches Of Genes And Proteins Devised
Often, the sequences of genes and proteins can suggest to us what their function is -- especially if we compare them with known sequences. Researchers have now developed a method that makes such analyses significantly more sensitive. (Sat, 07 Mar 2009 01:25:43 GMT)

On Sale Now: Ethics
The New York Times reports that Virginia Commonwealth University signed a deal with Philip Morris that prevents professors from publishing or discussing their research without the tobacco giant's permission -- contrary to the school's own rules. (Sat, 07 Mar 2009 03:23:08 GMT)

Linnaeus, Meet the Web
Announcing their plans in May to build an online Encyclopedia of Life , evolutionary biologists hope to create a comprehensive, online catalog of the genome and phylogeny of all known species on the planet. (Sat, 07 Mar 2009 03:23:19 GMT)

Here in the US, It's Politics Aplenty
We're aflutter with politics today. First, people are flocking to ScienceDebate2008, a group attempting to get clear stances from political candidates about their scientific views. Barack Obama stepped up and answered the group's 14 questions (John McCain has said he will answer them too). (Sat, 07 Mar 2009 03:23:29 GMT)

In This Case, Being Lucky Takes a Whole Lot of Work
Northwestern University's Richard Silverman and his work leading to the discovery and marketing of Pfizer's blockbuster, Lyrica, are profiled in this Chicago Tribune article. (Sat, 07 Mar 2009 03:23:39 GMT)

Fumes From SJ Biochemical Firm Hospitalize Three
SAN JOSE, Calif. -- A biochemical firm was shut down Friday by San Jose firefighters after fumes from a chemical leak sent two inspectors and a facility employee to the hospital, a fire captain said. (Sat, 07 Mar 2009 04:51:28 GMT)

Beats, Booze and Brains: Where Nerds Party
Club for fun-loving nerds aims to make science cool in the Big Apple. (Sat, 07 Mar 2009 06:01:07 GMT)

Be indispensable: Skills to beat the recession
It's going to be a very different world out there. Here are some hints for preparing for it. (Sat, 07 Mar 2009 18:28:44 GMT)

Be indispensable: Skills to beat the recession
It's going to be a very different world out there. Here are some hints for preparing for it. (Sat, 07 Mar 2009 19:54:23 GMT)

Harvard Scientists’ Discovery Opens Door to Synthetic Life
March 7 (Bloomberg) -- Harvard University scientists are a step closer to creating synthetic forms of life, part of a drive to design man-made organisms that may one day be used to help produce new fuels and create biotechnology drugs. (Sat, 07 Mar 2009 23:10:58 GMT)

Lab Cartoon
Julius Brennecke is studying small RNA pathways in Drosophila using DNA sequencing technologies, genetics, bioinformatics, and cell biology. (Sun, 08 Mar 2009 03:38:09 GMT)

Pacific Biosciences, Beijing Genomics Institute Shenzhen, Fluidigm, Stanford University, Sequenom, Chinese University ...
Menlo Park, Calif.-based Pacific Biosciences said two weeks ago that it recently received $20 million in funding from new investor Blackstone Cleantech Venture Partners. (Sun, 08 Mar 2009 03:38:19 GMT)

Welcome to Your 15 Minutes
Over at Buzzyeah, Andrew Meyer blogs about his weekend stint being interviewed on a radio show about genetic testing. The segment also included a VP from DNA Direct, says Meyers, who recently got his genome results from 23andMe. (Sun, 08 Mar 2009 03:38:39 GMT)

On This Slide, You See...
We've all been there, at a conference where the speakers use so much text on their slides that it is barely legible — not that you have enough time to read it because the moderator didn't really moderate and the speaker has to fly through his talk. (Sun, 08 Mar 2009 03:38:49 GMT)

Pledge from Obama ignites new hope among cancer researchers, survivors
CHICAGO — Echoing the words of former President Richard Nixon almost 40 years earlier, President Barack Obama in his speech to Congress last month expressed his commitment to launching an effort to find "a cure for cancer in our time." (Sun, 08 Mar 2009 06:12:44 GMT)

Be indispensable: Skills to beat the recession
It's going to be a very different world out there. Here are some hints for preparing for it. (Sun, 08 Mar 2009 06:52:28 GMT)

Be indispensable: Skills to beat the recession
It's going to be a very different world out there. Here are some hints for preparing for it. (Sun, 08 Mar 2009 10:49:36 GMT)

Shanghai Team Analyzes Mechanism That Enables Adult Cells To Behave Like Embryonic Stem Cells
Agilent Technologies Inc. (NYSE:A) today announced its collaboration with a team from the Shanghai Institutes for Biological Sciences and Tongi University that has achieved new insight into how adult cells can be induced to act like embryonic stem cells (ESC), with the ability to form any type of tissue known as "pluripotency. (Sun, 08 Mar 2009 11:19:13 GMT)

State needs new economic plan
Right now, our state is in the thick of an economic hurricane. As job opportunities spiral downward and the unemployment rate climbs higher, it is clear that we need an updated statewide economic strategy. (Sun, 08 Mar 2009 13:41:51 GMT)

Be indispensable: Skills to beat the recession
It's going to be a very different world out there. Here are some hints for preparing for it. (Sun, 08 Mar 2009 16:37:55 GMT)

INNOVATION:
Harvard University scientists are a step closer to creating synthetic forms of life, part of a drive to design man-made organisms that may one day be used to help produce new fuels and create biotechnology drugs. (Sun, 08 Mar 2009 18:49:18 GMT)

Saudi woman appointed editor of medical journal
RIYADH: A Saudi scientist has been appointed as associate editor of prestigious BMC Genomics, an online journal published by the UK-based BioMed Central. (Mon, 09 Mar 2009 00:09:38 GMT)

Engineered cell engine is step to artificial life
U.S. scientists said they have taken an important step toward making an artificial life form by making a ribosome -- the cell's factory. (Mon, 09 Mar 2009 01:07:15 GMT)

Engineered cell engine is step to artificial life
WASHINGTON (Reuters) - U.S. scientists said they have taken an important step toward making an artificial life form by making a ribosome -- the cell's factory. (Mon, 09 Mar 2009 01:07:15 GMT)

Biomarkers Going Mainstream
In a Wall Street Journal article today, columnist Sharon Begley introduces readers to the concept of biomarker tests. The hope and hype are both familiar to the scientific community but, until recently, have remained under the radar of the general public. (Mon, 09 Mar 2009 03:38:09 GMT)

The Sweet Smell of Posterboard
ScienceWoman is spending the day judging entries to the Intel International Science and Engineering Fair. On her blog, she posts some pictures of the entries from these young whippersnappers. (Mon, 09 Mar 2009 03:38:19 GMT)

Talk About High Performance
SiCortex unveiled a new high-performance computer, an SC648, that can analyze complex genomics at the rate of billions of calculations per second. And all of this is -- wait for it -- powered by eight to 10 bicyclists . The bike team rides to generate power to meet the consumption demands of the supercomputer and keep the calculations moving quickly. (Mon, 09 Mar 2009 03:38:29 GMT)

When It Comes To Blogging, Trackbacks Are Important, Too!
At A Blog Around the Clock, the online community manager over at PLoS ONE tallies up the number of comments already posted to the first Journal Club discussion this fall, led by Jonathan Eisen. (Mon, 09 Mar 2009 03:38:39 GMT)

Watch Out for the Falling Axe
In the latest round of job cuts in the pharma sector, Bristol-Myers Squibb announced it will be cutting 10 percent more of its 37,000-person workforce (they had a 10 percent reduction last year), according to the Wall Street Journal 's Health Blog. "Add in weak pipelines of new drugs, tough regulatory scrutiny, and pricing pressure from big purchasers, and it's clear why the industry is seeing ... (Mon, 09 Mar 2009 03:38:49 GMT)

The Short Read Headache
One of the biggest challenges these days for next-gen sequencing is informatics, and that ranges from primary analysis to secondary alignment and assembly. (Mon, 09 Mar 2009 03:53:09 GMT)

Sanger Institute Adds 11 Illumina GAs; Broad to Test Five Additional SOLiDs
This article has been updated from a previous version to clarify the Broad's prior installed base of SOLiDs. The institute had three systems, not two as initially reported. (Mon, 09 Mar 2009 03:53:19 GMT)

Early detection: Dr. Jon Klein’s lab works on a test for those at risk of diabetes
In the tradition of collaboration that medical practitioners and academicians so frequently tout, Dr. Jon B. Klein’s team of researchers has contributed to many studies, including those related to such illnesses as cancer and Alzheimer’s disease. (Mon, 09 Mar 2009 05:02:08 GMT)

Be indispensable: Skills to beat the recession
It's going to be a very different world out there. Here are some hints for preparing for it. (Mon, 09 Mar 2009 05:53:46 GMT)

Critical Growth Factor That Stimulates Sperm Stem Cells To Thrive Identified By Penn Veterinary Researchers
Researchers at the University of Pennsylvania School of Veterinary Medicine and Pennsylvania State University have identified for the first time a specific "niche factor" in the mouse testes called colony stimulating factor 1, Csf1, that has a direct effect on sperm stem cell self-renewal. (Mon, 09 Mar 2009 10:17:44 GMT)

LifeSciences BC Announces Recipients of the 2009 LifeSciences British Columbia Awards
VANCOUVER, British Columbia----LifeSciences British Columbia today announced the recipients of the 2009 LifeSciences British Columbia Awards. They are: (Mon, 09 Mar 2009 11:00:00 GMT)

Bruker Launches Numerous New High-Performance Scientific Instruments and Innovative Analytical Solutions at Pittcon®
At Pittcon 2009, Bruker Corporation (NASDAQ: BRKR) launches numerous new scientific and analytical products and solutions. The new systems and solutions introduced today are focused on bringing more productivity and specificity to confident routine analysis, and on opening new horizons for advanced research applications. (Mon, 09 Mar 2009 11:29:40 GMT)

Translational Genomics Research Institute and Applied Biosystems Accelerate Use of Genomics Research for Medical ...
CARLSBAD, Calif.----Applied Biosystems, a division of Life Technologies Corporation , and the Translational Genomics Research Institute today announced a strategic alliance designed to accelerate research into complex diseases and medical conditions. (Mon, 09 Mar 2009 11:30:00 GMT)

Translational Genomics Research Institute and Applied Biosystems Accelerate Use of Genomics Research for Medical ...
Applied Biosystems, a division of Life Technologies Corporation (NASDAQ:LIFE), and the Translational Genomics Research Institute today announced a strategic alliance designed to accelerate research into complex diseases and medical conditions. As part of this alliance, a team of scientists from TGen and Applied Biosystems will employ the SOLiD™ 3 System, Applied Biosystems’ next-generation ... (Mon, 09 Mar 2009 11:43:20 GMT)

EXACT Sciences Receives NASDAQ Compliance Notice
EXACT Sciences Corporation (NASDAQ: EXAS) today announced that, on March 6, 2009, the Company received notice from the Listing Qualifications Staff of The NASDAQ Stock Market (the “Staff”) that the Company no longer satisfies Marketplace Rule 4310(c)(3), which requires a listed security to maintain a minimum $35 million in market value of listed securities, or stockholders' equity of at least ... (Mon, 09 Mar 2009 12:28:09 GMT)

Virginia Tech professor under state auditor inquiry
A state auditor said Friday former Virginia Bioinformatics Institute Director Bruno Sobral has been under review for at least the past three months. Sobral is still a researcher and professor employed at Virginia Tech. (Mon, 09 Mar 2009 13:21:11 GMT)

We Predict Serious Competition in Sequencing Service Shops
Keith Robison has a post at Omics! Omics! about Cofactor Genomics, a next-gen sequencing services company based in St. Louis, Mo. The company's currently offering to "generate & assemble 680Mb of sequence (from an Illumina machine) for the paltry sum of $4.7K," Robison writes. (Mon, 09 Mar 2009 14:08:08 GMT)

Applied Biosystems, TGen Form Sequencing Alliance
NEW YORK (GenomeWeb News) – Applied Biosystems, a business of Life Technologies, announced today that has formed a strategic alliance with the Translational Genomics Research Institute. (Mon, 09 Mar 2009 14:38:29 GMT)

NCGR Using Kognitio's Database
NEW YORK (GenomeWeb News) – The National Center for Genome Resources is using an analytical database made by the UK bioinformatics firm Kognitio, NCGR said today. (Mon, 09 Mar 2009 14:38:39 GMT)

On the Block
Merck and Schering-Plough will be joining forces in a $41.1 billion cash-and-stock deal, reports the Wall Street Journal . The Journal adds that pharma companies are suffering from a host of problems, "from product pipelines that likely won't be able to offset companies' blockbusters that will lose patent protection in the coming years to the potential of increased government pressure to lower ... (Mon, 09 Mar 2009 15:23:09 GMT)

Get Your Applications Together
At his blog, Juniorprof wonders if new investigators without R01s are essentially out of luck when it comes to receiving stimulus funding. Capital improvement grants, he says, are targeted to those already with a large grant, while the challenge grants pose the problem of experience. (Mon, 09 Mar 2009 15:23:29 GMT)

National Center for Genome Resources Chooses Kognitio WX2
Kognitio has announced that the National Center for Genome Resources (NCGR) has deployed Kognitio’s WX2 purpose-built database to handle the analytical processing of multiple terabytes of research data in order to improve human health and crop improvement through genome sequencing and analysis. read more (Mon, 09 Mar 2009 16:05:45 GMT)

Signature Genomic Laboratories to Present at Invest Northwest 2009
Signature Genomic Laboratories, LLC, today announced an executive from the company will present a corporate update and an overview of the company at Invest Northwest 2009 in Seattle, Wash. (Mon, 09 Mar 2009 16:29:09 GMT)

Transport behavior of E. coli varies depending on manure source
( Crop Science Society of America ) New research was conducted studying the transport behavior of different strains of E. coli in an attempt to understand their movement through water supplies. Commonly only a single strain of E. coli is used in these studies, but with research showing that a significant amount of genetic variability exists among various strains, a more detailed study was ... (Mon, 09 Mar 2009 16:30:49 GMT)

Proteome Sciences Secures German ISO Certification
NEW YORK (GenomeWeb News) – Proteome Sciences said today that it has received ISO certification in Germany for its contract research lab in Frankfurt. (Mon, 09 Mar 2009 18:23:09 GMT)

Seahorse Bioscience Acquires BioProcessors; Raises Private Cash
NEW YORK (GenomeWeb News) – Seahorse Biosciences has acquired BioProcessors, a manufacturer of systems for developing and optimizing production of biological products from mammalian cell culture, for an undisclosed sum. (Mon, 09 Mar 2009 18:38:09 GMT)

Obama Signs Memo to "Protect" Science
NEW YORK (GenomeWeb News) – At the White House signing this afternoon of an executive order to overturn the previous administration's ban on using human embryonic stem cells in research, US President Barack Obama also signed a memorandum that he said is aimed at insulating science from politics. (Mon, 09 Mar 2009 18:53:10 GMT)

SBIR, STTR Bypassed in Stimulus Package
NEW YORK (GenomeWeb News) – Although none of the $10.4 billion in National Institutes of Health funding from the $787 billion stimulus package was marked to go to the two small business research funding efforts that NIH is supposed to fund, small businesses are invited to apply for funding through the $200 million the institutes have set aside for the new Challenge Grants program. (Mon, 09 Mar 2009 19:53:14 GMT)

Study Published by Rosetta Genomics and Collaborators in the Journal of Clinical Oncology Shows MicroRNA-based ...
PHILADELPHIA & REHOVOT, Israel----Rosetta Genomics Ltd. and collaborators announced today the results of a research study, showing for the first time that a microRNA-based diagnostic test can objectively identify squamous lung cancer with 96% sensitivity. (Mon, 09 Mar 2009 20:12:00 GMT)

Study Published by Rosetta Genomics and Collaborators in the Journal of Clinical Oncology Shows MicroRNA-based ...
Rosetta Genomics Ltd. (Nasdaq:ROSG) and collaborators announced today the results of a research study, showing for the first time that a microRNA-based diagnostic test can objectively identify squamous lung cancer with 96% sensitivity. The study, posted today on the Journal of Clinical Oncology’s Web site, [1] was carried out in collaboration with researchers at Columbia University, NYU Cancer ... (Mon, 09 Mar 2009 20:30:30 GMT)

Around the Regions
The nation's largest biotechnology clusters, and a smaller cluster with an established institute for regenerative medicine, on Monday projected their economies would benefit from President Obama's lifting of federal restrictions on human embryonic stem cell, or hESC, research, implemented in 2001 by predecessor George W. Bush. (Mon, 09 Mar 2009 21:38:29 GMT)

The curious chromosomes of a curious fruit
Incipient sex chromosomes have been found in New Zealand's eponymous export, the kiwifruit. Researchers writing in the open-access journal BMC Genomics have mapped the kiwifruit genome and pin-pointed the sex-determining locus. (Mon, 09 Mar 2009 23:33:48 GMT)

200,000 Rice Mutants Available Worldwide For Scientific Investigation
Researchers have estimated the number of different rice mutants needed to have a mutant for every gene as somewhere between 180,698 and 460,000. Two hundred thousand rice mutants are now available and have been mapped. (Tue, 10 Mar 2009 03:25:43 GMT)

NIH Grants in Bioinformatics Awarded Sept. — Oct. 2008
Marian Walhout is focused on using an innovative method she helped develop to elucidate differential gene expression in C. elegans . Instead of starting with a transcription factor of interest and then proceeding to locate its binding site in the genome, Walhout’s method starts with a piece of DNA and then attempts to discover the transcription factors that bind to it. (Tue, 10 Mar 2009 03:38:08 GMT)

National Genomegraphic
National Geographic 's February issue features a couple of articles for the genomics crowd. The short interview with Francis Collins covers a lot of ground, including genetic determinism, neurotheology, and, of course, the problem of evil. (Tue, 10 Mar 2009 03:38:19 GMT)

Another Acquisition in Next-Gen Sequencing
So here's a circular post if ever there was one. We're sending you to the Omics! Omics! blog from Keith Robison, which in turn refers to a few news items from our sister publication GenomeWeb Daily News. (Tue, 10 Mar 2009 03:38:29 GMT)

Monsanto's Historic R&D Investment has Contributed to Mid-20s Gross Profit Growth for Its Seeds and Genomics Segment
Tolerance Technology Crosses Another Key Regulatory Milestone (Tue, 10 Mar 2009 08:00:00 GMT)

Isilon and Ocarina Partner to Maximize Efficiency of File-Based Data Storage
Isilon® Systems , the proven leader in scale-out NAS, and Ocarina Networks, a leader in content-aware compression and dedupe for online storage, today announced an integrated nearline archive solution combining Isilon's new 36NL and Ocarina's ECOsystem storage optimization software. (Tue, 10 Mar 2009 10:00:00 GMT)

Isilon Spans File-Based Storage Needs With New Scale-Out NAS Products
Based Data While Reducing Capital and Operational Expenditures (Tue, 10 Mar 2009 10:00:00 GMT)

Key Challenges and Issues Facing the Dermatological Therapeutics Markets
NEW YORK----Reportlinker.com announces that a new market research report is available in its catalogue. (Tue, 10 Mar 2009 10:42:00 GMT)

Focus on the Liquid Chromatography Markets (LC, HPLC and UHPLC)
NEW YORK----Reportlinker.com announces that a new market research report is available in its catalogue. (Tue, 10 Mar 2009 10:58:00 GMT)

Photos: Making beautiful music with the earliest computers
The bleeps and beeps of the world's earliest computers are being crafted into electronic riffs for a 21st century music concert. The codebreaking computer used in World War II, the Colossus Mark II, and vintage machines ranging from the 1960s' Elliott 803 through to the 1980s' BBC Micro - will sing again as part of the Obsolete project, which is using early computers to make electronic ... (Tue, 10 Mar 2009 11:41:27 GMT)

Cell Biosciences Announces First UK System Sale
Cell Biosciences, Inc., a provider of nanoproteomic analysis systems to life science researchers, today announced the sale of its flagship protein analysis system to The University of Manchester's Stem Cell and Leukaemia Proteomics Laboratory, led by Professor Tony Whetton. (Tue, 10 Mar 2009 13:00:00 GMT)

Grain News
London— Monsanto 's historic investment in research and development in breeding and biotechnology has contributed to a 24 percent compound annual growth rate for the company's Seeds and Genomics segment since 2001. (Tue, 10 Mar 2009 13:00:29 GMT)

Rosetta Genomics Publishes Data on Lung Cancer Test
NEW YORK (GenomeWeb News) – Rosetta Genomics and its research collaborators have published in the Journal of Clinical Oncology data from a study showing that the same biomarker used in the firm's miRNA-based test for squamous lung cancer provided 96 percent sensitivity. (Tue, 10 Mar 2009 14:38:13 GMT)

Univ. of Manchester Buys Cell Biosciences System
NEW YORK (GenomeWeb News) – Cell Biosciences has sold one of its protein analysis systems to The University of Manchester, the company said today. (Tue, 10 Mar 2009 14:38:51 GMT)

Luminex Corporation to Present at Cowen and Company Annual Healthcare Conference
Luminex Corporation (NASDAQ: LMNX) today announced that management will present at the Cowen and Company 29 th Annual Healthcare Conference to be held March 16-19, 2009, in Boston. (Tue, 10 Mar 2009 14:44:10 GMT)

Study of protein structures reveals key events in evolutionary history
( University of Illinois at Urbana-Champaign ) A new study of proteins, the molecular machines that drive all life, also sheds light on the history of living organisms. (Tue, 10 Mar 2009 15:03:59 GMT)

Monsanto's historic R&D investment has contributed to mid-20s gross profit growth for its seeds and genomics segment - ...
Monsanto 's historic investment in research and development in breeding and biotechnology has contributed to a 24 percent compound annual growth rate for the company's Seeds and Genomics segment since 2001. This is one of the key messages Kerry Preete, Monsanto's Vice President of International Commercial, will tell investors today as part of a presentation at the Credit Suisse 14th Annual ... (Tue, 10 Mar 2009 15:06:03 GMT)

DNASTAR launches ArrayStar v3.0 gene expression analysis software with RNA-Seq capability
DNASTAR, Inc. , a leading bioinformatics software company, today announced the released of its latest upgrade to its gene expression analysis software. (Tue, 10 Mar 2009 15:51:37 GMT)

Interactive High-Def Cinema and Animation, Green Computing, Rural Broadband Take CENIC’s 2009 Innovations in ...
Four groundbreaking projects that focus on the innovative use and expansion of high-performance networking were honored by the Corporation for Education Network Initiatives in California (CENIC) as recipients of the 2009 Innovations in Networking Awards . (Tue, 10 Mar 2009 16:14:21 GMT)

Denator Launches Stabilizor T1 - Instant Stabilization Of Tissue Samples Upstream Enhances Quality And Value Of ...
Denator AB has laucnhed StabilizorTM T1, the company's first commercially available system for instant stabilization of tissue samples. Rapid degradation of proteins and peptides in ex vivo samples is a well known problem facing scientists trying to establish proteomic and peptidomic profiles in normal or diseased states. (Tue, 10 Mar 2009 16:18:36 GMT)

Further 100 Million Euros Allocated to Netherlands-Based R&D Targeting the Early Diagnosis and Treatment of Disease
The Center for Translational Molecular Medicine - the Dutch public-private partnership committed to the research and development of new techniques for the diagnosis and treatment of major diseases - today announced that eight new research projects will receive funding from the CTMM. (Tue, 10 Mar 2009 16:22:00 GMT)

Further 100 Million Euros Allocated to Netherlands-Based R&D Targeting the Early Diagnosis and Treatment of Disease
EINDHOVEN, The Netherlands, March 10 /PRNewswire/ -- The Center for Translational Molecular Medicine (CTMM) - the Dutch public-private partnership committed to the research and development of new techniques for the diagnosis and treatment of major diseases - today announced that eight new research projects will receive funding from the CTMM. It means that almost 250 million Euros have now been ... (Tue, 10 Mar 2009 16:34:35 GMT)

New Report - Prospering in a Down Market: Strategies for Life Science Suppliers
BioInformatics, LLC announces availability of its newest report, Prospering in a Down Market: (Tue, 10 Mar 2009 16:51:00 GMT)

Short Reads
Applied Biosystems, a business of Life Technologies, said this week that has formed a strategic alliance with the Translational Genomics Research Institute to sequence human disease samples on SOLiD sequencers. (Tue, 10 Mar 2009 18:08:13 GMT)

Canada Gives $2.3M Grant for Cod Genomics
NEW YORK (GenomeWeb News) – The Canadian government has given C$3 million ($2.3 million) to Genome Atlantic to conduct genomics studies of the Atlantic cod in order to understand what causes a developmental problem in the fish. (Tue, 10 Mar 2009 18:53:39 GMT)

Q&A: NCGR's Greg May on Building a Next-Gen Genome Center from Scratch
In 2007, the National Center for Genome Resources installed its first Illumina Genome Analyzer, marking a shift from pure bioinformatics research to both data production and analysis. (Tue, 10 Mar 2009 19:08:12 GMT)

New Product Watch
Febit this week said that its microRNA Geniom biochips have been updated to reflect the updated content of miRBase version 13.0, which was released by the Wellcome Trust Sanger Institute this week. (Tue, 10 Mar 2009 19:23:29 GMT)

NCGR, Beyond Batten Foundation Mull Next-Gen Sequencing for Carrier Screening Test
The National Center for Genome Resources has teamed up with the Beyond Batten Disease Foundation to develop an inexpensive carrier screening test for approximately 400 rare genetic disorders, possibly using second-generation sequencing. (Tue, 10 Mar 2009 19:38:12 GMT)

Roche NimbleGen, Neuromuscular Disorder Group to Merge CGH, Sequencing Data in Study
Roche NimbleGen announced last month that the Neuromuscular Disorder-Chip Consortium, a European Union's Seventh Framework Programme for Research and Technical Development, will use its microarrays for genetic research on neuromuscular disorders. (Tue, 10 Mar 2009 19:53:19 GMT)

Funding Update
The aim of this study is to "identify proteins with large scale changes in expression, and then focus on protein expression of classical protein kinase C (PKC) isoforms and proteins associated with these isoforms in failing human hearts." (Tue, 10 Mar 2009 19:53:29 GMT)

Recreational genomics: Will that be a paternity or cancer test today?
( University of Montreal ) Commercial genetic tests, which can verify risks of cancer risks to paternity, have become commonplace in the Western societies. Yet these tests provide little information and raise a lot more questions, says Bryn Williams-Jones, a professor at the University of Montreal Department of Social and Preventive Medicine and director of bioethics programs. (Tue, 10 Mar 2009 20:42:16 GMT)

Study of protein structures reveals key events in evolutionary history
(PhysOrg.com) -- A new study of proteins, the molecular machines that drive all life, also sheds light on the history of living organisms. (Tue, 10 Mar 2009 21:50:27 GMT)

Study of protein structures reveals key events in evolutionary history
A new study of proteins, the molecular machines that drive all life, also sheds light on the history of living organisms. (Wed, 11 Mar 2009 01:51:51 GMT)

And Still a Quarter of Them Believe the Sun Revolves Around the Earth. Ouch.
Over at his Genomics, Evolution, and Pseudoscience blog, Steven Salzberg has a post on the current public understanding of some basic scientific principles . The US National Science Board published the results of its latest report, which comes out every two years and serves as a gauge of how well Joe Consumer has learned (or has chosen to accept) fairly basic concepts. (Wed, 11 Mar 2009 03:53:19 GMT)

Protein structures reveal "big bang" of innovation in evolution
A new study of proteins, the molecular machines that drive all life, also sheds light on the history of living organisms. (Wed, 11 Mar 2009 09:51:51 GMT)

NuGEN Taps Erwin Estigarribia to Lead Manufacturing and Quality Operations
SAN CARLOS, Calif.----NuGEN Technologies, Inc., a leader in nucleic acid sample preparation announced today that it has hired Erwin V. Estigarribia to serve as the company's vice president of operations reporting to Elizabeth Hutt, chief executive officer. (Wed, 11 Mar 2009 10:00:00 GMT)

NuGEN Taps Erwin Estigarribia to Lead Manufacturing and Quality Operations
NuGEN Technologies, Inc., a leader in nucleic acid sample preparation announced today that it has hired Erwin V. Estigarribia to serve as the company’s vice president of operations reporting to Elizabeth Hutt, chief executive officer. Estigarribia will lead manufacturing and quality initiatives, and direct the company in achieving cGMP compliance by the end of 2009. (Wed, 11 Mar 2009 10:13:20 GMT)

Study Shows MicroRNA-Based Diagnostic Identifies Squamous Lung Cancer With 96% Sensitivity
Rosetta Genomics Ltd. (Nasdaq:ROSG) and collaborators announced the results of a research study, showing for the first time that a microRNA-based diagnostic test can objectively identify squamous lung cancer with 96% sensitivity. (Wed, 11 Mar 2009 10:18:04 GMT)

Video: HSBC's ethical cash Isa is helping children in Sierra Leone
Tony Levene travels to Sierra Leone to see first-hand how a new ethical investment Isa is transforming children's lives (Wed, 11 Mar 2009 12:35:37 GMT)

Gentel and Eprogen Announce Partnership to Commercialize Whole Proteome Arrays
MADISON, Wis.----Gentel® Biosciences, a protein microarray life sciences company, announces a technology partnership with Eprogen® to create products for the discovery of new autoantibody biomarkers using whole proteome microarrays. (Wed, 11 Mar 2009 13:00:00 GMT)

Agilent to Shift Life Science Focus from R&D to Profits
CHICAGO (GenomeWeb News) – Agilent Technologies is looking to generate a greater return on its R&D investments in the life science space, according to a company official. (Wed, 11 Mar 2009 13:53:09 GMT)

State set to revise biotech policy
With an aim of making Karnataka the leader in biotechnology sector in Asia, the state government is planning to come out with a revised ‘millennium biotech policy’ which will be announced shortly. (Wed, 11 Mar 2009 14:13:55 GMT)

Agilent Exec Says Success for Life Science Biz Means Shift from R&D Emphasis to Profits
CHICAGO – Agilent Technologies plans to focus its life science strategy on generating a greater return on its previous R&D investments in the space, according to a company official. (Wed, 11 Mar 2009 14:23:09 GMT)

Gentel, Eprogen Ink Proteome Array Pact
NEW YORK (GenomeWeb News) – Gentel Biosciences and Eprogen today said that they will collaborate on making whole proteome microarrays for identifying new autoantibody biomarkers. (Wed, 11 Mar 2009 14:39:03 GMT)

Research and Markets: Orion Genomics Product Pipeline Analysis Provides Details on Clinical Trials for Products in ...
DUBLIN, Ireland----Research and Markets has announced the addition of Global Markets Direct's new company profile "Orion Genomics Product Pipeline Analysis" to their offering. (Wed, 11 Mar 2009 15:41:00 GMT)

Research and Markets: Orion Genomics Product Pipeline Analysis Provides Details on Clinical Trials for Products in ...
Research and Markets ( http://www.researchandmarkets. ) has announced the addition of Global Markets Direct's new company profile " Orion Genomics Product Pipeline Analysis " to their offering. (Wed, 11 Mar 2009 15:51:18 GMT)

From Detection to Drugs
Giselle Knudsen wants to find a better way to detect proteins in cells. To this end, she is developing Raman spectroscopy, a detection method based on how the sample scatters light from a laser, for the life sciences, particularly proteomics and cancer drug target development. (Wed, 11 Mar 2009 16:23:12 GMT)

European Food Safety Authority: Application (Reference EFSA-GMO-NL-2008-51) for the placing on the market of ...
This document provides a scientific opinion of the Scientific Panel on Genetically Modified Organisms (GMO Panel) of the European Food Safety Authority (EFSA) on genetically modified (GM) cotton GHB614 (Unique Identifier BCS-GHØØ2-5) developed to provide tolerance to glyphosate-based herbicides. (Wed, 11 Mar 2009 17:07:00 GMT)

Dutch Translational Research Center Provides 100M Euros in Funding for Research Projects
NEW YORK (GenomeWeb News) – The Center for Translational Molecular Medicine, a Dutch public-private partnership founded a year ago, said that it has awarded a total of €100 million ($128 million) to eight new research projects targeting cancer, cardiovascular, neurodegenerative, and infectious diseases. (Wed, 11 Mar 2009 19:08:11 GMT)

People Transfer
Arizona State University said last week that it has appointed Alan Nelson as director of the Biodesign Institute. (Wed, 11 Mar 2009 19:08:29 GMT)

CollabRx Debuts Cancer Genomics Service to Distinguish Itself from DTC Genomics Firms
CollabRx said it plans to educate patients about its newly launched predictive cancer-genotyping service and link researchers through a web-based portal, but the company will not follow the direct-to-consumer model of existing personal-genomics companies. (Wed, 11 Mar 2009 19:08:40 GMT)

The medium is the message: Manipulating salmonella in spaceflight curtails infectiousness
The medium is the message: Manipulating salmonella in spaceflight curtails infectiousness (Wed, 11 Mar 2009 21:24:04 GMT)

Bioinformatics sheds light on evolutionary origin of Rickettsia virulence genes
( Virginia Tech ) Scientists from three universities have revealed that genes for a specific type of molecular secretion system in Rickettsia, a structure that is linked in many cases to virulence, have been conserved over many years of evolution. (Thu, 12 Mar 2009 00:12:24 GMT)

Students given ability to be 'Phage Hunters'
BYU freshmen and sophomores have an unprecedented opportunity to take part in a national research project next year that involves isolating and naming a new virus strain. (Thu, 12 Mar 2009 03:29:09 GMT)

The Year of Personal Genomics
A feature story in Discover magazine rounds up the progress that personal genomics companies have made in 2007, as well as what consumers should expect from them . Though some tests can make relatively concrete predictions (like Agendia's FDA-approved MammaPrint), SNP screening can only offer the probability of developing a certain disease. (Thu, 12 Mar 2009 03:53:19 GMT)

Bioinformatics sheds light on evolutionary origin of Rickettsia virulence genes
Scientists from the Virginia Bioinformatics Institute (VBI) at Virginia Tech, the University of Maryland School of Medicine, and the University of Louisville have revealed that genes for a specific type of molecular secretion system in Rickettsia, a structure that is linked in many cases to virulence, have been conserved over many years of evolution. (Thu, 12 Mar 2009 05:13:54 GMT)

Reportlinker Adds Global Biochips Market Analysis and Forecasts
NEW YORK----Reportlinker.com announces that a new market research report related is available in its catalogue. (Thu, 12 Mar 2009 09:54:00 GMT)

CombiMatrix Receives New Contract From NASA
MUKILTEO, Wash., March 12, 2009 -- CombiMatrix Corporation announced today that it has received a four year contract for $858,298 from NASA's Ames Research Center to design and test a microfluidic system that incorporates CombiMatrix's semiconductor microarray as part of an integrated genetic analysis platform that can be deployed in satellites. (Thu, 12 Mar 2009 10:00:00 GMT)

Estrogen activates critical lung genes to improve lung function following preterm birth
Estrogen may be a new postnatal therapy to improve lung function and other outcomes in preterm infants, researchers at UT Southwestern Medical Center have found in an animal study. (Thu, 12 Mar 2009 11:12:39 GMT)

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