Bioinformatics News Mar 2009: bioinformatics, genomics, proteomics, microarray, etc.

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Suddenly, Twitter's the rage with D.C. politicos
Missouri's U.S. senator becomes the latest to make waves with the microblogging site--this time suggesting when Obama would announce his choice for Health and Human Services head. (Sun, 01 Mar 2009 00:31:02 GMT)

Origin of Life On Earth: Scientists Unlock Mystery Of Molecular Machine
A major mystery about the origins of life may have been resolved. Scientists have proposed a new theory for how a universal molecular machine, the ribosome, managed to self-assemble as a critical step in the genesis of all life on Earth. (Sun, 01 Mar 2009 01:26:46 GMT)

This Week in Nature
In early online publication, UCLA researchers have constructed a global map of human genetic variation using large-scale genotyping data. (Sun, 01 Mar 2009 02:23:29 GMT)

Ring in the New Year and the Ouija Board, Too
It's that time again -- when half the people think about the year in retrospect and the other half of the people start thinking about what's going to happen next year. (Sun, 01 Mar 2009 02:23:49 GMT)

The case against enterprise micro-blogging
Twitter and its clones seem like a good idea for the enterprise-until you realize that the short message format is just no good for business. (Sun, 01 Mar 2009 02:24:08 GMT)

At ASMS, Mass-Spec Vendors Debut Tools to Meet Growing Demand for Better Performance
DENVER — As mass-spectrometry vendors search for the next breakthrough in instrument technology, a number of them unveiled a host of new tools this week they claim offer greater mass accuracy and resolution, depth of coverage, and sensitivity. (Sun, 01 Mar 2009 02:38:09 GMT)

Sreelatha Menon: Researchers sans borders
A global net-based project for finding a new TB drug sets the pace for research into poor man's diseases that don't attract big money. Call it Science 2.0 or merely science without borders. (Sun, 01 Mar 2009 06:51:51 GMT)

FE Editorial : Poll vaults
A Politically-savvy Martian arriving in India last week would have known elections must be due; such was the extraordinary energy the government displayed in making decisions, and announcing and clearing projects. (Sun, 01 Mar 2009 20:30:24 GMT)

At Scripps Meeting, Speakers See Optimistic Future for Genomic Medicine Despite Challenges Ahead
SAN DIEGO (GenomeWeb News) – Genomic information is already having an impact on medical practice, and advances in technologies such as next-generation sequencing will only accelerate the advance of genomic medicine, according to speakers at a conference here this week. (Sun, 01 Mar 2009 21:23:08 GMT)

Apple gives up a little Internet usage share
Use of the Mac operating system to access the Web slides a little, but Apple's iPhone "dominates" the mobile browsing market, new reports indicate. (Sun, 01 Mar 2009 22:26:05 GMT)

CollabRx Launches Personal Genomics Service to Target 'Long Tail' of Disease
NEW YORK (GenomeWeb News) – CollabRx last week threw its hat in the personal genomics market with the launch of a new service designed to provide cancer patients with information about specific treatment options that their physicians might otherwise overlook. (Mon, 02 Mar 2009 01:23:09 GMT)

Make your own shoe phone online
Aussie computer scientist develops a real version of Maxwell Smart's phone. (Mon, 02 Mar 2009 03:28:42 GMT)

Malaria Parasite Zeroes In On Molecule To Enhance Its Survival
Scientists have found that the parasite that causes malaria breaks down an important amino acid in its quest to adapt and thrive within the human body. By depleting this substance called arginine, the parasite may trigger a more critical and deadlier phase of the disease. The work may point the way to better treatments. (Mon, 02 Mar 2009 04:13:46 GMT)

Genome Sequencing Of Fungus With Biotechnological Applications
Researchers Antonio G. Pisabarro (Professor of Microbiology) as well as José Luis Lavín and José Antonio Oguiza, from the Genetic and Microbiology Group at the Public University of Navarre, have taken part in the international project for the sequencing of the genome of the Postia placenta fungus. (Mon, 02 Mar 2009 04:59:24 GMT)

BioScience tip sheet, March 2009
( American Institute of Biological Sciences ) The press release provides a listing of peer-reviewed research articles published in the March 2009 issue of BioScience, the journal of the American Institute of Biological Sciences. The journal's tag line is "Organisms from Molecules to the Environment." (Mon, 02 Mar 2009 05:14:48 GMT)

Mining MIT for Neurotechnical Know-How
Where do innovative ideas come from and how can we accelerate them? That's the challenge and mandate of MIT's McGovern Institute Neurotechnology (MINT) program. MINT supports innovative new projects that can drive the future development of neuroscience. (Mon, 02 Mar 2009 05:36:59 GMT)

Researchers fear 'stagnation' under Tories
Warn that Ottawa's approach will make it tough for Canada to recruit or retain top talent (Mon, 02 Mar 2009 06:34:33 GMT)

Epistem Announces Research and Development Collaboration With a Major Pharmaceutical Company
MANCHESTER, England, March 2 /PRNewswire/ -- Epistem Plc (LSE:EHP) the UK biotechnology and research services company announced today that they have signed a research and development collaboration with Novartis to identify new drug targets and therapeutics across a variety of disease areas. (Mon, 02 Mar 2009 07:19:30 GMT)

Report: Intel, TSMC tie-up targets Atom chip
Intel and Taiwan Semiconductor Manufacturing Company will collaborate on Atom chip manufacturing, according to reports. (Mon, 02 Mar 2009 07:39:08 GMT)

Aussie boffin cobbles together Get Smart shoe phone
Forty years after clumsy agent Maxwell Smart immortalised the shoe phone, an Australian computer scientist has developed a real-life version. (Mon, 02 Mar 2009 09:33:18 GMT)

Dr. Fox: Dog's mornings are gut-wrenching
DEAR DR. FOX: I hope you can shed some light on a perplexing problem we have with our 3-year-old neutered Westie. When Remy came to us, the Animal Rescue League sent him with a bag of Nutra brand lamb and rice dry food, but he wouldn't touch it. (Mon, 02 Mar 2009 09:39:53 GMT)

The Einstein Center for Epigenomics, of Albert Einstein College of Medicine, Signs Site License Agreement with CLC bio
AARHUS, Denmark----The Einstein Center for Epigenomics at the Albert Einstein College of Medicine in Bronx, New York, has entered into an agreement with CLC bio to put the company's full suite of bioinformatics tools into the hands of epigenomics researchers and other investigators at the College. (Mon, 02 Mar 2009 12:00:00 GMT)

Biotechnological Applications For Genome Sequencing Of Fungus
Researchers Antonio G. Pisabarro (Professor of Microbiology) as well as JosÃ© Luis LavÃn and JosÃ© Antonio Oguiza, from the Genetic and Microbiology Group at the Public University of Navarre, have taken part in the international project for the sequencing of the genome of the Postia placenta fungus. (Mon, 02 Mar 2009 12:16:47 GMT)

The Einstein Center for Epigenomics, of Albert Einstein College of Medicine, Signs Site License Agreement with CLC bio
The Einstein Center for Epigenomics at the Albert Einstein College of Medicine in Bronx, New York, has entered into an agreement with CLC bio to put the company's full suite of bioinformatics tools into the hands of epigenomics researchers and other investigators at the College. The suite includes CLC bio’s premier solutions for handling high-throughput sequencing data, CLC Genomics Workbench ... (Mon, 02 Mar 2009 12:30:56 GMT)

EmTech Spl: Customized medicine to be a reality?
NEW DELHI, INDIA: “Development of biological sciences –genomics, proteomics and systemic biology and their integration with allied sciences is what is going to drive the future,” these were the words with which Dr M.K.Bhan, secretary, Department of Biotechnology opened the session titled 'Advances in Biotechnology' at the first day of EmTech India 2009 organized jointly by MIT and CyberMedia in ... (Mon, 02 Mar 2009 12:47:02 GMT)

Obama: 'A cure for cancer in our time'
Echoing the words of former President Richard Nixon almost 40 years earlier, President Barack Obama last week expressed his commitment to launching a new effort to find "a cure for cancer in our time." (Mon, 02 Mar 2009 12:51:44 GMT)

Facebook investor talks about why Twitter bid failed
Peter Thiel of Clarium Capital said a few words to BusinessWeek about why a deal between the two companies wasn't going to work out. Hint: it involves Facebook's cloudy valuation. (Mon, 02 Mar 2009 13:16:38 GMT)

Microsoft and FathomDB target 'relational' clouds
Two seemingly unconnected pieces of news signal an interesting market test: can standard relational-database software be effectively delivered from the cloud? (Mon, 02 Mar 2009 13:24:08 GMT)

New antivirus software looks at behaviors, not signatures
In the war with online scammers, security vendors like AVG and Damballa are increasingly turning to software that monitors behavior of code rather than its signature. (Mon, 02 Mar 2009 14:08:22 GMT)

Are passwords our best security option?
When even the most careful and security-minded PC users fall prey to password thieves, you have to think that there must be a better way. (Mon, 02 Mar 2009 14:39:18 GMT)

Einstein College Licenses CLC Bio Packages
NEW YORK (GenomeWeb News) – Researchers at Albert Einstein College of Medicine will use two CLC Bio software platforms in its epigenomics and other research programs under a new site license agreement, the Danish company said today. (Mon, 02 Mar 2009 15:23:30 GMT)

FlexGen Closes New Round of Financing
FlexGen, a Dutch Life Sciences company, is active in the genetic research market with a proprietary custom microarray synthesis instrument. The financing will allow FlexGen to speed up the development and global commercialization of its FlexArrayer, an instrument that provides researchers with unprecedented freedom in the production of custom microarrays. (Mon, 02 Mar 2009 16:00:00 GMT)

Opinions Wanted
Russ Altman blogs that he's giving a talk "highlighting some of the most important papers in our field of translational bioinformatics" and he's looking for input . Nominate papers from the last 15 months that include molecular and clinical data with bioinformatics tools. (Mon, 02 Mar 2009 16:08:29 GMT)

Initial reactions to my Kindle 2
The Kindle 2 still has growing up to do, but this iteration is still a convenient way to read when on the go. It offers a qualitatively different experience from reading on a laptop or a phone. (Mon, 02 Mar 2009 16:09:08 GMT)

Open standards aid intracompany collaboration
Open standards aren't simply a tool with which to club competitors; they also help companies get their own product lines working together. (Mon, 02 Mar 2009 17:24:35 GMT)

Melinda Gates admits to having iPhone envy
In a recent interview with Vogue, Melinda Gates says that the Gates children aren't allowed to have iPods or iPhones--but she "acknowledges the inevitable lure of the forbidden fruit." (Mon, 02 Mar 2009 17:39:08 GMT)

Verdezyne Names VP
Carlsbad-based Verdezyne, which was formerly known as CODA Genomics, said Thursday it has named Damien Perriman as Vice President of Business Development. Verdezyne said that Perriman joins the firm from The Dow Chemical Company, and has previously served as Deputy Trade Commissioner to the Americas for the Queensland Government of Australia, along with working at Miritone. Verdezyne is ... (Mon, 02 Mar 2009 17:43:29 GMT)

TiVo partnerships target cable market
TiVo announced a couple of partnerships Monday that will help it win business cable operators. (Mon, 02 Mar 2009 19:24:28 GMT)

TiVo partnerships target cable market
Company announces a couple of deals to help make the next generation of TiVo HD products more cable friendly. (Mon, 02 Mar 2009 19:31:47 GMT)

JCVI program trains USDA scientists on eukaryotic genome analysis
( J. Craig Venter Institute ) As part of the ongoing mission to train and educate scientists on the latest tools, methods and advances in genomics, the J. Craig Venter Institute's Eukaryotic Genome Annotation and Analysis Team will travel to Lubbock, Texas, March 3-5 to train 40 US Department of Agriculture scientists at the Agricultural Research Service. (Mon, 02 Mar 2009 20:12:44 GMT)

Microsoft to start testing 'Kumo' search service
Beginning this week, some of Redmond's employees will get access to the new look for Microsoft's Live Search, CNET News has learned. (Mon, 02 Mar 2009 20:24:28 GMT)

USDA Grants $11M for Livestock Genomics
NEW YORK (GenomeWeb News) – Universities and research centers in 15 states will receive a total of $11 million from the US Department of Agriculture for livestock genomics research projects and the development of technologies under a Cooperative State Research, Education, and Extension Service program. (Mon, 02 Mar 2009 20:38:19 GMT)

Microsoft enthusiasts atwitter at MVP summit
The gathering with tech enthusiasts is closed to the press, but there are hundreds of tweets an hour discussing everything from the food to the allegedly secret content. (Mon, 02 Mar 2009 20:46:02 GMT)

Researchers discover gene variant associated with cocaine dependence, cocaine induced paranoia
Researchers from Boston University School of Medicine and Yale University School of Medicine and the University of Connecticut School of Medicine, have discovered that variants in the a-endomannosidase gene are associated with cocaine addiction and cocaine-induced paranoia in European American and African American populations. These findings appear in the March issue of the Archives of General ... (Mon, 02 Mar 2009 21:33:39 GMT)

New Forensic Method Aims to Predict What a Person Looks Like from DNA Sample
(PhysOrg.com) -- A University of Arizona research team recently completed a study looking at the DNA blueprint of almost 1,000 individuals and comparing that to detailed measurements of their hair, skin and eye color. (Mon, 02 Mar 2009 23:19:43 GMT)

Quest for young talent
KUALA LUMPUR: Nine million children aged below 14 will be tested by a local university for their intelligence and creativity under a programme to identify and developed talented youths. (Mon, 02 Mar 2009 23:49:45 GMT)

Boffin cobbles together shoe phone
An Australian computer scientist has developed a mobile phone housed in a shoe. (Tue, 03 Mar 2009 09:18:51 GMT)

Genetic variant linked to cocaine addiction identified
Washington, Mar 3 : In a novel study, an international team of researchers has identified a genetic variant linked to cocaine addiction and cocaine-induced paranoia. (Tue, 03 Mar 2009 09:23:44 GMT)

HP and Partners HealthCare Extend Collaboration in Support of Personalized Medicine
HP (NYSE:HPQ) and Partners HealthCare today announced the extension of a successful five-year, multi-million dollar agreement to develop software and implement hardware and services supporting Partners’ efforts to accelerate clinical genomics and advance personalized medicine. (Tue, 03 Mar 2009 12:58:06 GMT)

Complete Genomics Announces Collaboration With the Broad Institute to Conduct Human Sequencing Studies
MOUNTAIN VIEW, Calif.----Complete Genomics Inc., a recently launched, third-generation human genome sequencing company, today announced a collaboration with the Broad Institute of MIT and Harvard to conduct complete human genome sequencing pilot studies of two cancers -- glioblastoma and melanoma. (Tue, 03 Mar 2009 13:00:00 GMT)

Abraxis BioScience Reports 2008 Fourth Quarter and Full-Year Financial Results
LOS ANGELES----Abraxis BioScience, Inc. , a fully integrated biotechnology company, today reported financial results for the fourth quarter and full year ended December 31, 2008. (Tue, 03 Mar 2009 13:05:00 GMT)

Latest Tools And Methods For Eukaryotic Genome Analysis: J. Craig Venter Institute To Train USDA Scientists
As part of the ongoing mission to train and educate scientists on the latest tools, methods and advances in genomics, the J. Craig Venter Institute's (JCVI) Eukaryotic Genome Annotation and Analysis Team will travel to Lubbock, TX March 3rd-5th to train 40 United States Agriculture Department (USDA) scientists at the Agricultural Research Service. (Tue, 03 Mar 2009 13:16:16 GMT)

Abraxis BioScience Reports 2008 Fourth Quarter and Full-Year Financial Results
Abraxis BioScience, Inc. (NASDAQ: ABII), a fully integrated biotechnology company, today reported financial results for the fourth quarter and full year ended December 31, 2008. (Tue, 03 Mar 2009 13:44:17 GMT)

HP, Partners HealthCare in collaboration
Hewlett-Packard Co. and Partners HealthCare on Tuesday announced an agreement to develop software and implement hardware and services they said will focus on clinical genomics and advance personalized medicine. (HPQ) (Tue, 03 Mar 2009 14:17:02 GMT)

Complete Genomics collaborates in cancer studies
Complete Genomics Inc. on Tuesday announced a collaboration with the Broad Institute of MIT and Harvard to conduct complete human genome sequencing pilot studies of glioblastoma and melanoma. (Tue, 03 Mar 2009 14:37:34 GMT)

Sigma-Aldrich Buys NextGen's Electrophoresis Business
NEW YORK (GenomeWeb News) – NextGen Sciences said today that it has sold its electrophoresis business to Sigma-Aldrich for an undisclosed sum. The Ann Arbor, Mich.-based company said the deal is part of its strategic realignment plan to pare back its operations and focus on its biomarker services. (Tue, 03 Mar 2009 15:53:20 GMT)

JCVI to Train USDA Scientists in Eukaryotic Genome Analysis
NEW YORK (GenomeWeb News) - The J. Craig Venter Institute will train a group of US Department of Agriculture scientists in genomic annotation and analysis methods that they may use later in their own research projects, JCVI said Monday. (Tue, 03 Mar 2009 15:53:30 GMT)

TRADE NEWS: Agilent Technologies Introduces Next-Generation Microarrays, Quadrupling Probe Density
SANTA CLARA, Calif.----Agilent Technologies Inc. today announced the introduction of its SurePrint G3 Microarrays. These third-generation Agilent microarrays contain up to one million probes on a standard 1in. x 3 in. glass slide. (Tue, 03 Mar 2009 16:00:00 GMT)

Harold Varmus Rocks
In case you missed Harold Varmus' appearance on the Daily Show last night, you can check out the video clip here . Jon Stewart had a good time pointing out that Varmus was considered a key scientist by the Clinton administration and now again by Obama's team -- but he had no such role during the Bush years. (Tue, 03 Mar 2009 16:08:20 GMT)

Mar 03rd
Despite the challenging backdrop, the East of England's companies continue to defy the global economic slowdown. Nowhere is this more evident than in the shortlist for Business Weekly's East of England Business Awards - announced today. (Tue, 03 Mar 2009 16:12:01 GMT)

TRADE NEWS: Agilent Technologies Introduces Next-Generation Microarrays, Quadrupling Probe Density
Agilent Technologies Inc. (NYSE:A) today announced the introduction of its SurePrint G3 Microarrays. These third-generation Agilent microarrays contain up to one million probes on a standard 1in. x 3 in. glass slide. Initial applications are array-based comparative genomic hybridization (aCGH) and copy number variation (CNV), with other applications to follow. (Tue, 03 Mar 2009 16:13:49 GMT)

The Complete Five
Over at Genetic Future, Daniel MacArthur blogs about Complete Genomics and its deal to sequence five genomes for the Broad Institute -- one genome of a well-studied test case, and four from "tumor and matched-pair normals" to study glioblastoma and melanoma. (Tue, 03 Mar 2009 16:23:19 GMT)

This Week in PLoS
Scientists have performed a comparative functional analysis of the C. elegans and D. melanogaster proteomes. Their work was published this week in PLoS Biology . Using shotgun proteomics, they identified more than half of all predicted C. elegans proteins. (Tue, 03 Mar 2009 16:53:09 GMT)

Research and Markets: Gene Expression Profiling Life Science
DUBLIN, Ireland----Research and Markets has announced the addition of the "Gene Expression Profiling Life Science Dashboard Series 2" report to their offering. (Tue, 03 Mar 2009 17:06:00 GMT)

All systems go
Some peculiar microorganisms are showing systems biology can color in what's missing from models of biochemical and cellular networks (Tue, 03 Mar 2009 17:12:33 GMT)

Best New Product Awards Winners Named at Molecular Medicine Tri-Conference
Products from AnaSpec, Accelrys, Almac Diagnostics, Seahorse Biosciences, BioFortis recognized for their innovation across the life industry. (Tue, 03 Mar 2009 18:05:00 GMT)

New study shows how spikes in nitrite can have
( Boston University ) A new study provides insight into how a short burst in nitrite can exert lasting beneficial effects on the heart, protecting it from stress and assaults such as heart attacks. In this study,researchers at Boston University School of Medicine have demonstrated for the first time that short elevations in circulating levels of this simple anion are sufficient to have a lasting ... (Tue, 03 Mar 2009 18:33:59 GMT)

New Products
Epicentre Biotechnologies has launched CircLigase II single-stranded DNA ligase. According to the company, the enzyme efficiently catalyzes the circularization of single-stranded DNA longer than 15 bases with no need for oligo bridges and virtually no linear or circular concatamers being produced. (Tue, 03 Mar 2009 19:23:09 GMT)

Paired Ends
Mort Minaee has joined 454 Life Sciences as head of regulatory affairs. He will be responsible for the regulatory approval process as the company prepares for the diagnostic use of the 454 sequencing technology. (Tue, 03 Mar 2009 19:23:19 GMT)

Protein function and chromatin structure methods featured in Cold Spring Harbor Protocols
Two new methods for analyzing the roles played by proteins in cells are featured in the March issue of Cold Spring Harbor Protocols. (Tue, 03 Mar 2009 19:48:39 GMT)

IP Roundup
Seiko Epson of Tokyo has received US Patent No. 7,497,544, "Droplet discharging head, droplet discharging device and manufacturing method of microarray." (Tue, 03 Mar 2009 20:08:09 GMT)

BioArray Briefs
Febit said this week that it will make its HybSelect target enrichment application for use by researchers involved in the EU-funded READNA Consortium. (Tue, 03 Mar 2009 20:08:19 GMT)

New Product Watch
BASE 2.10 has been released. New features include a Biomaterial LIMS system. BASE is a free web-based database solution for microarray analysis data developed at Lund University . (Tue, 03 Mar 2009 20:08:29 GMT)

In Print
Journal: Analytical Biochemistry . 2009 Feb 15;385(2):203-7. Title: Correlation analysis of external RNA controls reveals its utility for assessment of microarray assay. (Tue, 03 Mar 2009 20:38:41 GMT)

DNAPrint Genomics Goes Bust
NEW YORK (GenomeWeb News) – Genetic testing company DNAPrint Genomics has shut down its operations, according to a notice on its website. The Sarasota, Fla.-based firm shut down operations sometime during the past month. (Tue, 03 Mar 2009 20:53:10 GMT)

Sequenom Hires PDI to Launch and Sell Prenatal Test
NEW YORK (GenomeWeb News) – Sequenom today said that it has inked a contract with sales and marketing services firm PDI to provide the sales force that will launch and commercialize the firm's SEQureDx non-invasive prenatal genetic screening tests. (Tue, 03 Mar 2009 20:53:19 GMT)

HP, Partners HealthCare Extend Personalized Medicine Collaboration
NEW YORK (GenomeWeb News) – Hewlett Packard and Partners HealthCare have extended an ongoing agreement to develop software and implement hardware and services supporting Partners' personalized medicine and clinical genomics program, HP said today. (Tue, 03 Mar 2009 20:53:29 GMT)

Complete Genomics, Broad to Study Cancer Genomes
For the project, Complete Genomics will use its DNA sequencing technology to sequence five samples provided by the Broad Institute. The first genome will be a sample that has already been studied extensively by the scientific community. (Tue, 03 Mar 2009 20:53:39 GMT)

LabCorp Collaborates with Duke in Operating Biorepository
NEW YORK (GenomeWeb News) – LabCorp said today that it has struck a collaborative agreement with Duke University covering operations at its Biorepository in Kannapolis, NC. (Tue, 03 Mar 2009 20:53:49 GMT)

FlexGen Raises Financing to Commercialize Arrayer, Develop Applications
FlexGen this week announced that it has closed "several million euros" in private-equity financing and said it plans to use the cash to further optimize its arrayer for use in a number of applications including genomic selection for second-generation sequencing and biomarker validation. (Tue, 03 Mar 2009 20:53:59 GMT)

LC Sciences Joins Agilent, NimbleGen, Febit, and Others in the Nascent Target Enrichment Market
LC Sciences, a Houston, Texas-based genomics and proteomics company, last week launched a custom target enrichment service for next-generation sequencing applications. (Tue, 03 Mar 2009 21:08:10 GMT)

Completing Platform Upgrade, Agilent Launches High-Density CGH and CNV Chips and Promises More
Agilent Technologies this week rolled out its SurePrint G3 microarray platform, which contains up to one million probes on a standard 1x3 inch glass slide — up from 244,000 probes on the last version of its chips. (Tue, 03 Mar 2009 21:38:09 GMT)

UB and AHRM, Inc. help Buffalo join the electronic medical revolution
The Obama administration's push to move health care from handwritten charts and prescriptions into the electronic age is getting a boost in Western New York with new funding to establish a Medication Management Research Network in the University at Buffalo's New York State Center of Excellence in Bioinformatics and Life Sciences. (Tue, 03 Mar 2009 22:07:03 GMT)

UNC Charlotte’s Five Ventures® Business Plan Competition Announces Keynote Speaker – Dr. Joshua Boger, CEO & Founder ...
Five Ventures® has announced its keynote speaker for April 9 th at UNC Charlotte – Dr. Joshua Boger, CEO and Founder of Vertex Pharmaceuticals, Inc. Dr. Boger, a native of Concord North Carolina, is one of the most respected biotechnology entrepreneurs in the world. Dr. Boger is the author of over 50 scientific publications, holds 31 issued U.S. patents in pharmaceutical discovery and ... (Tue, 03 Mar 2009 22:13:56 GMT)

New study shows how spikes in nitrite can have
A new study provides insight into how a short burst in nitrite can exert lasting beneficial effects on the heart, protecting it from stress and assaults such as heart attacks. In this study, just published in Circulation Research, researchers at Boston University School of Medicine have demonstrated for the first time that short elevations in circulating levels of this simple anion are ... (Tue, 03 Mar 2009 23:19:43 GMT)

Harvard's Sunyaev on the Evolution of Exon Resequencing's Ability to Find Human Trait Genes
Shamil Sunyaev's research at Harvard Medical School focuses on analyzing human resequencing data from an evolutionary, functional, and medical-genetics perspective, and on developing methods for predicting functional effects of mutations. (Tue, 03 Mar 2009 23:23:29 GMT)

CombiMatrix to Co-Market Strand Genomics Microarray Analysis Software
NEW YORK, July 9 (GenomeWeb News) - Acacia's CombiMatrix group will market Strand Genomics' microarray analysis software, the companies said yesterday. (Wed, 04 Mar 2009 03:09:01 GMT)

Centergy to present economic development initiatives to lawmakers
MARSHFIELD -- A regional partnership designed to spur economic development in central Wisconsin plans to lobby later this month for financial support for renewable energy, construction and health care initiatives. (Wed, 04 Mar 2009 10:41:14 GMT)

Illumina to Present at Upcoming Investment Conferences in March
Illumina, Inc. (NASDAQ:ILMN) today announced that the Company will webcast its presentations at two upcoming investment conferences. (Wed, 04 Mar 2009 11:14:00 GMT)

Breakthrough in Culturing Intracellular Bacteria Aided by Biolog's Phenotype MicroArray Technology
HAYWARD, Calif.----A major breakthrough publication, published last Friday in the February 27 early edition of the Proceedings of the National Academy of Sciences, describes studies that were greatly aided by utilizing Biolog Phenotype MicroArray technology to advance our understanding of an important class of pathogenic bacteria. (Wed, 04 Mar 2009 12:45:00 GMT)

Breakthrough in Culturing Intracellular Bacteria Aided by Biolog’s Phenotype MicroArray™ Technology
A major breakthrough publication, published last Friday in the February 27 early edition of the Proceedings of the National Academy of Sciences, describes studies that were greatly aided by utilizing Biolog Phenotype MicroArray technology to advance our understanding of an important class of pathogenic bacteria. (Wed, 04 Mar 2009 12:58:10 GMT)

Center of Excellence project will serve as statewide model, reduce errors, boost efficiency
BUFFALO, N.Y. -- The Obama administration's push to move health care from handwritten charts and prescriptions into the electronic age is getting a boost in Western New York with new funding to establish a Medication Management Research Network in the University at Buffalo's New York State Center of Excellence in Bioinformatics and Life Sciences. (Wed, 04 Mar 2009 14:20:30 GMT)

Spikes In Nitrite Can Have Lasting Protective Impact On The Heart
A new study provides insight into how a short burst in nitrite can exert lasting beneficial effects on the heart, protecting it from stress and assaults such as heart attacks. Researchers have demonstrated for the first time that short elevations in circulating levels of this simple anion are sufficient to have a lasting impact on the heart by modulating its oxidation status and its protein ... (Wed, 04 Mar 2009 15:12:24 GMT)

Good News for Cancer Patients (the Ones in Boston, Anyway)
This article from the Boston Globe reports that Massachusetts General Hospital will begin to routinely perform genetic screens on "nearly all new patients' tumors, a novel strategy designed to customize treatment." (Wed, 04 Mar 2009 15:23:09 GMT)

Sequenom Adopts Shareholder Rights Plan
NEW YORK (GenomeWeb News) – Sequenom today said that its board of directors has approved the adoption of a share purchase rights plan, under which shareholders of record at the close of business on March 20, will receive rights to purchase shares of a new series of preferred stock. (Wed, 04 Mar 2009 15:38:09 GMT)

Rutgers to Build $55M Proteomics Building
NEW YORK (GenomeWeb News) – Rutgers University plans to use a portion of money from a recent capital campaign to fund construction of a $55 million proteomics research center it has been planning to build since 2006. (Wed, 04 Mar 2009 15:38:29 GMT)

Removing the Guesswork
A paper published this week in PNAS from scientists at the Broad Institute looks at how to better identify the proteins to which small molecules and drugs bind to effect their mechanism of action. (Wed, 04 Mar 2009 15:53:09 GMT)

Mar 04th
As production of one of the world’s most important food crops fails to keep up with demand, threatened by droughts and new diseases, a team of British scientists is undertaking important genetic research on wheat that is hoped will help underpin food security in the UK. (Wed, 04 Mar 2009 15:57:11 GMT)

Safeway gives $685,000 to TGen for breast cancer research
( The Translational Genomics Research Institute ) Despite a down economy, Safeway Inc. presented a $685,236 check this week for breast cancer research at the Translational Genomics Research Institute (TGen).Dan Valenzuela, President of Safeway's Phoenix Division, which includes 116 stores throughout Arizona, thanked the grocery chain's customers and employees for stepping up for scientific ... (Wed, 04 Mar 2009 16:47:33 GMT)

Rosetta Genomics to Hold Fourth Quarter Conference Call on March 26
REHOVOT, Israel & PHILADELPHIA----Rosetta Genomics today announced it will release financial results for the fourth quarter of 2008 on March 26, 2009 before the opening of NASDAQ trading, and will host a conference call and webcast to discuss those results and answer questions beginning at 8:30 a.m. (Wed, 04 Mar 2009 16:57:00 GMT)

Rosetta Genomics to Hold Fourth Quarter Conference Call on March 26
Rosetta Genomics (NASDAQ: ROSG) today announced it will release financial results for the fourth quarter of 2008 on March 26, 2009 before the opening of NASDAQ trading, and will host a conference call and webcast to discuss those results and answer questions beginning at 8:30 a.m. Eastern time that same day. (Wed, 04 Mar 2009 17:13:35 GMT)

Luminex Unveils Keynote Speakers for Planet xMAP USA 2009
AUSTIN, Texas----Luminex Corporation , the worldwide leader in multiplexed solutions, today unveiled the keynote speakers for its sixth annual Planet xMAP USA 2009 multiplexing symposium. (Wed, 04 Mar 2009 18:00:00 GMT)

Protein Function And Chromatin Structure Methods Featured In Cold Spring Harbor Protocols
Two new methods for analyzing the roles played by proteins in cells are featured in the March issue of Cold Spring Harbor Protocols. Thomas J. Wandless and colleagues from Stanford University provide detailed instructions for Regulating Protein Stability in Mammalian Cells Using Small Molecules. (Wed, 04 Mar 2009 18:02:24 GMT)

Luminex Unveils Keynote Speakers for Planet xMAP USA 2009
Luminex Corporation (Nasdaq: LMNX), the worldwide leader in multiplexed solutions, today unveiled the keynote speakers for its sixth annual Planet xMAP USA 2009 multiplexing symposium. Planet xMAP USA 2009 will feature keynote addresses from Dr. Mark McClellan, Dr. Francis Collins, and Dr. Andrea Ferreira-Gonzalez. The Luminex hosted symposium will be held May 4-6, 2009, at the Hyatt Regency ... (Wed, 04 Mar 2009 18:13:52 GMT)

UPVCC needs P490M for bldg. on SRP lot
THE University of the Philippines in the Visayas Cebu College (UPVCC), who received from the Cebu City Government five hectares of the South Road Properties (SRP) for its graduate school campus, needs P490.1 million in financial requirements for Phase I alone. (Wed, 04 Mar 2009 18:31:49 GMT)

People Transfer
Fate Therapeutics, a company founded in late 2007 to commercialize stem-cell technology from several US academic institutions, said this week that it has added Dan Shoemaker as its chief technology officer. (Wed, 04 Mar 2009 19:23:41 GMT)

Researchers at Signature Characterize Previously Unrecognized DNA Gains on Human Chromosome 22
SPOKANE, Wash.----Researchers at Signature Genomic Laboratories recently characterized 18 individuals with submicroscopic gains of DNA on chromosome 22 and suggest that duplication alone may not account for the clinical features in those individuals. (Wed, 04 Mar 2009 20:00:00 GMT)

Grocer Gives TGen $685K for Breast Cancer Research
NEW YORK (GenomeWeb News) – The Translational Genomics Research Institute today said that it has received a gift of $685,236 from the supermarket chain Safeway for its breast cancer research programs. (Wed, 04 Mar 2009 20:23:12 GMT)

GeneLink Raises $2.4M in Private Placements
NEW YORK (GenomeWeb News) – GeneLink today said that it has raised $2.4 million through two private placements of its stock. (Wed, 04 Mar 2009 20:23:21 GMT)

Genescient Teams with Kronos on Alzheimer’s Research
NEW YORK (GenomeWeb News) – Genescient and Kronos Science Laboratory will collaborate to identify genes that may be involved in Alzheimer’s disease, Genescient said today. (Wed, 04 Mar 2009 20:23:33 GMT)

200,000 rice mutants available worldwide for scientific investigation
( Virginia Tech ) Researchers have estimated the number of different rice mutants needed to have a mutant for every gene as somewhere between 180,698 and 460,000. Two hundred thousand rice mutants are now available and have been mapped. (Wed, 04 Mar 2009 20:49:03 GMT)

CombiMatrix Corporation Reports Fourth Quarter and Year-End 2008 Financial Results
MUKILTEO, Wash., March 4, 2009 -- CombiMatrix Corporation today reported financial results for the three and 12 months ended December 31, 2008. Key highlights for the fourth quarter and through the date of this release include: (Wed, 04 Mar 2009 21:00:00 GMT)

Affymetrix to Webcast Presentations at Two March Financial Conferences
Affymetrix, Inc. (NASDAQ:AFFX) today announced that company management will provide a corporate overview at two upcoming financial conferences. (Wed, 04 Mar 2009 21:14:42 GMT)

Pressure BioSciences' Q4 Revenues Nearly Double
NEW YORK (GenomeWeb News) – Pressure BioSciences today reported that its fourth-quarter revenues nearly doubled and its net loss declined 8 percent year over year, amid a restructuring that included the firm cutting its workforce by 40 percent. (Wed, 04 Mar 2009 21:23:08 GMT)

Barcelona Genomics Center Buys Genomatix Analyzer
NEW YORK (GenomeWeb News) – A Barcelona biomedical research center focused on genomic studies has bought a Genomatix Genome Analyzer for use in its disease and epigenetics studies, Genomatix said today. (Wed, 04 Mar 2009 21:23:18 GMT)

CombiMatrix Presents Preliminary Data on Comprehensive Cancer Array Test
An investigational microarray test that measures miRNA expression patterns to detect the presence of cancer and distinguish between cancers has yielded promising preliminary data, according to CombiMatrix. (Wed, 04 Mar 2009 21:23:29 GMT)

ICx Wins Mass Spec Contract for South Korea
NEW YORK (GenomeWeb News) – ICx Technologies has been awarded a multi-year contract worth up to $40 million to work with partners to develop a biological and chemical mass spectrometer for use by the South Korean military. (Wed, 04 Mar 2009 21:38:55 GMT)

Helicos Co-Founder Says He Sequenced Own Genome on Company's Platform
Helicos BioSciences co-founder Steve Quake has sequenced his own genome using the Helicos Genetic Analysis System, the first human genome reported to be sequenced using the company's single-molecule platform. (Wed, 04 Mar 2009 22:08:30 GMT)

200,000 rice mutants available worldwide for scientific investigation
Scientists across the world are building an extensive repository of genetically modified rice plants in the hope of understanding the function of the approximately 57,000 genes that make up the genome of Oryza sativa. (Wed, 04 Mar 2009 22:36:33 GMT)

Wonder If There's Johnnie Walker, Too
In a festive Thanksgiving mood , Sandra Porter decided to find out more about turkeys. After looking up wild turkeys in NCBI, she found a lot of interesting taxonomic information, including pictures of different species. (Thu, 05 Mar 2009 03:08:29 GMT)

This Week in Nature
Nature hits the newsstands today, which means we hit the books to bring you our weekly round-up of articles worth reading. In news this week, the magazine checks in on metabolomics. (Thu, 05 Mar 2009 03:08:39 GMT)

That Would Explain the Zebra Fish Boom in Home Aquariums
Hey, zebra fish researchers: you've got a new set of admirers. The New York Times offers this Q&A with biologist Steven Farber , who in his spare time heads up a nonprofit group that brings zebra fish to inner-city classrooms in an attempt to teach kids about genetics and the scientific approach in general. (Thu, 05 Mar 2009 03:08:49 GMT)

Top 10 Innovations for 2008
Bitesize Bio's Nick points readers to The Scientist magazine's list of the top 10 innovations in the life sciences in 2008. While you have to subscribe to view the list in its entirety, Nick rounds up the highlights: an in vivo multispectral imaging system that can view molecular movement in small animals in nearly real time; a Fucci (fluorescent ubiquitination-based cell cycle indicator)-based ... (Thu, 05 Mar 2009 03:08:59 GMT)

Einstein Center for Epigenomics signs site license agreement with CLC bio
The Einstein Center for Epigenomics at the Albert Einstein College of Medicine in Bronx, New York, has entered into an agreement with CLC bio to put the company's full suite of bioinformatics tools into the hands of epigenomics researchers and other investigators at the College. (Thu, 05 Mar 2009 08:49:31 GMT)

Research and Markets: New Opportunities for Novel Diagnostic Approaches and Therapies within Neural Signaling
DUBLIN, Ireland----Research and Markets has announced the addition of John Wiley and Sons Ltd's new report "Neural Signaling: Opportunities for Novel Diagnostic Approaches and Therapies" to their offering. (Thu, 05 Mar 2009 09:51:00 GMT)

5th Biomarker Workshop at the NMI in Reutlingen another Success
The Biomarker Workshop held at the NMI has become a fixed date for many researchers from a number of countries. This year, the one-day workshop took place on 4th March and welcomed about 80 guests and eight speakers. (Thu, 05 Mar 2009 10:44:15 GMT)

Spikes In Nitrite Can Have Heart Benefits
A new study provides insight into how a short burst in nitrite can exert lasting beneficial effects on the heart, protecting it from stress and assaults such as heart attacks. (Thu, 05 Mar 2009 11:17:43 GMT)

Bruker Daltonics Announces Opening of maXis U.S. Demonstration Facility and Installations in Top-tier Laboratories ...
BILLERICA, Mass.----Bruker Daltonics today announced the opening of its Massachusetts demonstration facility for the ultra-high resolution time-of-flight maXis™ mass spectrometer, as well as several maXis installations in top-tier U.S. life-science research laboratories. (Thu, 05 Mar 2009 12:00:00 GMT)

Children at Kids' Tech University learn why computer programs can be so frustrating
BLACKSBURG — Saturday, about 400 children descended on the Haymarket Theater in Virginia Tech's Squires Student Center to take part in Kids' Tech University. (Thu, 05 Mar 2009 12:00:58 GMT)

Bruker Daltonics Announces Opening of maXis™ U.S. Demonstration Facility and Installations in Top-tier Laboratories ...
Bruker Daltonics today announced the opening of its Massachusetts demonstration facility for the ultra-high resolution time-of-flight (UHR-TOF) maXis™ mass spectrometer , as well as several maXis installations in top-tier U.S. life-science research laboratories. The revolutionary maXis , which Bruker will exhibit at PITTCON 2009 next week in Chicago, is the only high-performance mass ... (Thu, 05 Mar 2009 12:28:50 GMT)

Breast Cancer Research: Safeway Gives $685,000 To TGen
Despite a down economy, Safeway Inc. presented a $685,236 check this week for breast cancer research at the Translational Genomics Research Institute (TGen). Dan Valenzuela, President of Safeway's Phoenix Division, which includes 116 stores throughout Arizona, thanked the grocery chain's customers and employees for stepping up for scientific research. (Thu, 05 Mar 2009 13:17:13 GMT)

Bruker Daltonics Announces Opening Of maXis™ U.S. Demonstration Facility And Installations In Top-tier Laboratories ...
Bruker Daltonics today announced the opening of its Massachusetts demonstration facility for the ultra-high resolution time-of-flight (UHR-TOF) maXisT mass spectrometer, as well as several maXis installations in top-tier U.S. life-science research laboratories. (Thu, 05 Mar 2009 13:18:47 GMT)

Bruker Opens Mass Spec Demo Facility
NEW YORK (GenomeWeb News) – Bruker said today that its Bruker Daltonics business has opened a demonstration facility in Massachusetts for its ultra-high resolution time-of-flight maXis mass spectrometer. (Thu, 05 Mar 2009 14:53:20 GMT)

Promega GoTaq® Goes Green with Latest Hot Start Offer
Promega Corporation, a global leader in DNA and RNA Analysis, will plant a tree for each GoTaq ® Hot Start product purchased through May 31st. This green initiative is designed to compliment the mission of life scientists around the world – to improve the lives of others now and for generations to come. The benefits of planting trees bring a long lasting impact much like the work and ... (Thu, 05 Mar 2009 16:14:37 GMT)

Shanghai Team Analyzes Mechanism That Enables Adult Cells to Behave Like Embryonic Stem Cells
Agilent Technologies Inc. (NYSE:A) today announced its collaboration with a team from the Shanghai Institutes for Biological Sciences and Tongi University that has achieved new insight into how adult cells can be induced to act like embryonic stem cells (ESC), with the ability to form any type of tissue known as “pluripotency.” (Thu, 05 Mar 2009 16:14:47 GMT)

You May Have to Build Your Own Desk, But It's Worth It
At Discovering Biology in a Digital World, Sandra Porter blogs about the excitement, adventure, and stomach-churning nerves that go along with starting a new company . Her startup aims "to develop instructional materials that help students and researchers use biological data," she writes, noting that a principal concern is getting people to pay for these materials. (Thu, 05 Mar 2009 16:53:09 GMT)

Just What You Needed: More Stats to Learn
A post from blogger Agnostic at Gene Expression asks whether the use of information criteria -- that is, how well an observation fits a statistical model with given hypotheses -- is beginning to replace p-values . While the community leans heavily on p-values, Agnostic notes that these measures are limited by their connection to a null hypothesis: "They do not allow us to decide which of a ... (Thu, 05 Mar 2009 16:53:19 GMT)

This Week in Nature
Harold Varmus has published an autobiography, which, according to a review, "shows why he is one of Barack Obama's top science advisers in Washington DC," explains Iain Mattaj, director general of EMBL. "His ability to connect basic research to medical application is frequently evident elsewhere in the book. (Thu, 05 Mar 2009 16:53:29 GMT)

Fingers Crossed, But We're Not Holding Our Breath
Derek Lowe has a post at In the Pipeline about Merck's new venture in open access . Sage, which will be headed up by Stephen Friend, is meant to "bring together genomic studies from all sorts of laboratories into a common format and database," Lowe writes. (Thu, 05 Mar 2009 16:53:39 GMT)

"Ouch" Just About Covers It
The Guardian reports on university angst in the UK as budgets were revealed to show tough hits for research . "Top universities including Imperial College London, University College London and Cambridge face substantial cuts this year after losing out in the allocation of £1.6bn of research funding," the story says. (Thu, 05 Mar 2009 17:38:09 GMT)

IP Update
Julius Brennecke is studying small RNA pathways in Drosophila using DNA sequencing technologies, genetics, bioinformatics, and cell biology. (Thu, 05 Mar 2009 18:08:08 GMT)

Products & Services
GeneCopoeia has recently launched a collection of microRNA functional analysis reagents and tools. (Thu, 05 Mar 2009 18:08:18 GMT)

New Products
Eksigent last week introduced the cHIPLC-nanoflex system for proteomics research. (Thu, 05 Mar 2009 19:53:09 GMT)

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