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Bioinformatics News 01/2009 (Page 4)

Team pinpoints gene that helps breast cancer tumors spread (Pioneer Press)
HACKENSACK, N.J. — A gene that makes breast cancer tumors more likely to resist chemotherapy and to spread to other organs has been identified by a team of New Jersey researchers.

Area school selected to participate in national genomic research project (Quincy Herald-Whig)
CANTON, Mo. -- Culver-Stockton College is one of 16 colleges to be selected to participate in the Howard Hughes Medical Institute's Science Education Alliance, which engages students in real-world scientific research as part of the National Genomic Research Initiative.

Sirius Genomics Teams with UK Genomics Group on Test for Infection-Drug Response (GenomeWeb News)
GenomeWeb Daily News You are not logged in. Existing subscribers login here . New to GenomeWeb Daily News? Register quickly here for your free subscription.

CombiMatrix Announces $1.5 Million Redemption of Auction Rate Securities (GlobeNewswire via Yahoo! Finance)
MUKILTEO, Wash., Jan. 9, 2009 -- CombiMatrix Corporation announced today that all of its $1.5 million in auction rate securities were recently liquidated at par value. Earlier in 2008, CombiMatrix had reported that these securities had become illiquid due to the global financial credit crisis.

The maintenance economy (Canadian Business)
Some (faint) hope for the new year.

Sequenom bids for Exact Science (San Diego Daily Transcript via Yahoo! News)
San Diego genomics company Sequenom Inc. (Nasdaq: SQNM) has made a move to acquire Exact Sciences Corp. (Nasdaq: EXAS), a genomics company in Marlborough, Mass., developing DNA-based technologies for cancer detection.

A*STAR to work on R&D partnerships with Belgium biologic firm (Channel NewsAsia via Yahoo! Singapore News)
SINGAPORE: A*STAR’s Bioprocessing Technology Institute (BTI) will be collaborating with GSK Biologicals SA Belgium in three vaccine and adjuvant system related research projects.

A*STAR to work on R&D partnerships with Belgium biologic firm (Channel NewsAsia via Yahoo! Malaysia News)
SINGAPORE: A*STAR’s Bioprocessing Technology Institute (BTI) will be collaborating with GSK Biologicals SA Belgium in three vaccine and adjuvant system related research projects.

Researchers find gene that helps breast cancer tumors spread (Newsday)
N.J. -- A gene that makes breast cancer tumors more likely to resist chemotherapy and to spread to other organs has been identified by a team of New Jersey researchers.

My Genome, My Self? (Slashdot)
theodp writes "After baring his DNA for the world to see, Steven Pinker follows up in the NYT Magazine with his take on the coming era of consumer genetics. Pinker comes away less wide-eyed than Time Magazine about the current predictive ability of $399 genetic tests, but is convinced enough to opt out of learning whether he has a gene that increases the risk of Alzheimer's and believes that ...

We are subgroups of one 'race' (The Cincinnati Enquirer)
The 1953 discovery of DNA as a linear string of bases, the ability to sequence these bases in the 1970s, and incredible advances in DNA sequencing techniques, combined with bioinformatics computer software during the past decade, have led to fantastic breakthroughs in our understanding of evolution and racial differences.

Study Of Dietary Fats Finds That Longer May Not Be Better (Medical News Today)
Researchers have uncovered why some dietary fats, specifically long-chain fats, such as oleic acid (found in olive oil), are more prone to induce inflammation. Long-chain fats, it turns out, promote increased intestinal absorption of pro-inflammatory bacterial molecules called lipopolysaccharides (LPS). This study appears in the January issue of JLR.

My genome, my self (International Herald Tribune)
In the coming era of consumer genetics, your DNA will have much to tell you about the biological bases of your health, your physique and even your personality.

My Genome, My Self (New York Times)
In the coming era of consumer genetics, your DNA will have much to tell you about the biological bases of your health, your physique and even your personality. But will this knowledge really amount to self-knowledge?

U-M researchers discover new genes that fuse in cancer (EurekAlert!)
( University of Michigan Health System ) Using new technologies that make it easier to sequence the human genome, researchers at the University of Michigan Comprehensive Cancer Center have identified a series of genes that become fused when their chromosomes trade places with each other. These recurrent gene fusions are thought to be the driving mechanism that causes certain cancers to develop.

Sunday, January 11, 2009 (GenomeWeb News)
2009 is likely to be a busy year for array manufacturers as firms with different resources and strengths seek to make good on previous promises to launch new chips and platforms, acquire complementary companies and technologies, and push new array-based tests out into the molecular diagnostics market.

Sunday, January 11, 2009 (GenomeWeb News)
At last week's High Content Analysis Conference in San Francisco, vendors presented new software to help scientists more deeply mine data from high-throughput workflows and to better manage, analyze, and store data flooding from high-content screening experiments.

Sunday, January 11, 2009 (GenomeWeb News)
In the study, which is based on data generated last spring and was published in Public Library of Science One two weeks ago, scientists from Columbia University found that the SOLiD platform led to fewer false-positive variants than the GA, while the GA called fewer false-negative variants compared to the SOLiD.

Monday, January 19, 2009 (GenomeWeb News)
While anticipated increases in government funding, next-generation sequencing, and emerging economies were highlighted as sources for maintaining financial equilibrium in 2009, proteomics was not at this week's JPMorgan Healthcare Conference.

Sunday, January 11, 2009 (GenomeWeb News)
Excuse us a moment while we toot our own horn, but GenomeWeb has a fancypants new website and we're pretty psyched about it. You probably already noticed the new look for your Daily Scan e-mail bulletin, and there's loads of new stuff on our website as well.

In this issue of Pharmacogenomics Reporter (GenomeWeb News)
Sequenom has submitted an offer to acquire Exact Sciences in an all-stock transaction valued at $41 million. CombiMatrix said that all of its $1.5 million worth of auction rate securities were recently liquidated.

Protein Forest Opens UK Office (GenomeWeb News)
NEW YORK (GenomeWeb News) – Protein Forest said this week that it has opened a European division headquartered in Newcastle upon Tyne, UK.

FDA Hopes to Publish MAQC II Results by End of ’09; Begins Sequencing QC Project (GenomeWeb News)
The second phase of the US Food and Drug Administration-hosted Microarray Quality Control project is on schedule to wrap up by the end of 2009 when the results of the effort are likely to be published in a major journal, such as Nature Biotechnology , according to MAQC II coordinator Leming Shi.

Bar Harbor Biotech Plans Three Product Launches to Reach Pharma, Academics (GenomeWeb News)
Bar Harbor Biotechnology , a two-year-old Jackson Laboratory spinout based in Trenton, Maine, that launched a suite of gene-expression-related products in late 2007, plans to begin selling a number of new tools this year.

Usability Analysis Could Bring Benefits to Bioinformatics Portals and Research (GenomeWeb News)
Usability should be engineered into the development process of web-based bioinformatics resources, particularly because databases and applications don’t grow in linear patterns, according to a team of researchers from the UK, the US, and Italy.

Q&A: Adding Theory to Experiment May Lend Another View of Stem-Cell Research (GenomeWeb News)
From Jan. 12-14 , the EuroSyStem Workshop in Leipzig, Germany, will explore methods, data-management tools, and theoretical approaches in the area of computational stem-cell biology.

FDA's SEQC Study to Assess Second-Gen Techs, Data Analysis for RNA Sequencing (GenomeWeb News)
The US Food and Drug Administration is organizing a new research study to “objectively assess the technical performance of different next-generation sequencing technologies” for DNA and RNA analyses, and to evaluate the pros and cons of various data analysis methods, according to a notice published in the Federal Register last month.

Protagen Closing in on Fourth Funding Round To Develop Biomarker-Based Diagnostics (GenomeWeb News)
Aiming to join the diagnostics field, German protein-analysis firm Protagen is preparing to close its fourth financing round to help it develop its diagnostics platform, its new CEO, Stefan Müllner, told ProteoMonitor this week.

NIH Dollars Not Expected to Offer Much Lift To Big-Ticket Vendors in ‘09, Report Says (GenomeWeb News)
Capital equipment firms such as mass-spectrometry makers are not likely to have an immediate benefit from an expected increase in National Institutes of Health funding in coming years, although other life-science vendors are, according to investment bank Leerink Swann Research.

Seppro Tech Buy Adds to Sigma-Aldrich’s Protein-Depletion, Antibody Product Lines (GenomeWeb News)
Sigma-Aldrich this week said it has expanded its protein-depletion and antibody product line by acquiring GenWay Biotech’s Seppro technology.

Personal Genomics on the Upswing (GenomeWeb News)
Harvard's Steven Pinker has an article in the New York Times Magazine describing his experience having his genome sequenced as one of the first 10 volunteers in George Church's Personal Genome Project.

Tecan May Increase Sales, Marketing Staff in New Shanghai Base in 2009 (GenomeWeb News)
Tecan will likely increase its array tools-related sales and marketing presence in China next year to accommodate what it calls a growing customer base, company officials said this week.

Illumina Rolls Out Certified Provider Program for Sequencing (GenomeWeb News)
NEW YORK (GenomeWeb News) – Illumina today rolled out a new certified service provider program for organizations offering next-generation sequencing services on its Genome Analyzer.

The Key to Affy's Lowered Prices? A New and Improved Genotyping Algorithm (GenomeWeb News)
Affymetrix this week said that it has reduced the price of its two-chip 500K SNP genotyping set to $250, and that it will offer the 500K set as a single array by the end of the year and will launch a million-SNP product by the first quarter of 2007.

NCI to Provide $90M for Cancer Genome Atlas Centers (GenomeWeb News)
NEW YORK (GenomeWeb News) — The National Cancer Institute has committed up to $90 million over the next five years to support between four and ten new centers to advance its Cancer Genome Atlas program.

EU Launches Project to Improve In-Vitro Diagnostics (Marketwire via Yahoo! Finance)
QIAGEN led-consortium to develop standards for patient sample processing in order to facilitate the discovery and prediction of diseases

EU Launches Project to Improve In-Vitro Diagnostics (n-tv.de)
Venlo, The Netherlands, January 12, 2009 - The European Union launched a new research project targeting to expand the potentials and utility of in-vitro diagnostics through the creation of new standards for the collection, handling and processing of blood, tissue, tumor and other sample materials.

Illumina and Oxford Nanopore Enter into Broad Commercialization Agreement (Centre Daily Times)
Illumina (NASDAQ:ILMN) and Oxford Nanopore Technologies (“Oxford Nanopore”) today announced a strategic alliance including a commercialization agreement and equity investment. Under the terms of the commercialization agreement, Illumina will exclusively market, sell, distribute, and service BASE™ Technology products developed by Oxford Nanopore for DNA sequencing into the research and diagnostic ...

DJ HUGIN NEWS/EU Launches Project to Improve In-Vitro Diagnostics (Financial.de)
QIAGEN led-consortium to develop standards for patient sample processing in order to facilitate the discovery and prediction of diseases Venlo, The Netherlands, January 12, 2009 - The European Union launched a new research project targeting to expand the potentials and utility of in-vitro diagnostics through the creation of new standards for the collection, handling and processing of blood, ...

My Pharmiweb.com (PharmiWeb)
AnaSpec Inc. AnaSpec has announced the release of its newest collection of ClearPointTM b-Amyloid peptides.

Conference Highlights TGen's And Scottsdale Healthcare's Contributions To Molecular Oncology (Medical News Today)
'The Sixth Vital Sign' runs Jan. 22-24 at the Arizona Grand Resort Physician-scientists from the Translational Genomics Research Institute (TGen) and Scottsdale Healthcare will present their latest findings and techniques at a national conference designed to provide cancer doctors with new treatments for their patients.

Illumina Genome Analyzer Selected by Internationally Recognized Medical Center to Sequence 50 Human Genomes (Centre Daily Times)
Illumina (NASDAQ:ILMN) today announced that researchers at Duke University Medical Center will utilize Illumina’s Genome Analyzer to study the resistance to HIV infection among 50 individuals that were highly exposed to the virus, but who remain uninfected. Duke University researchers will sequence the complete genome of at least 50 individuals with the desired phenotype.

Rubicon Genomics Announces a Licensing Agreement With Abbott to Develop and Commercialize DNA Methylation Cancer Tests (PR Newswire via Yahoo! Finance)
Rubicon Genomics today announced a licensing agreement with Abbott, which marks the achievement of significant milestones within their on-going Research and Option Agreement for development and commercialization of Rubicon MethylPlex methylation detection technology for the diagnosis and prognosis of cancer.

New Technology For Detecting Gene Fusions Opens Field In Cancer Research (Medical News Today)
Using new technologies that make it easier to sequence the human genome, researchers at the University of Michigan Comprehensive Cancer Center have identified a series of genes that become fused when their chromosomes trade places with each other. These recurrent gene fusions are thought to be the driving mechanism that causes certain cancers to develop.

Thomson Reuters White Paper Explores the Role of Biomarkers in Clinical Trials and Drug Development (ITNews)
PHILADELPHIA and LONDON, January 12 /PRNewswire/ -- Thomson Reuters today announced that it has published a new white paper on the topic of biomarkers drawing on expert insight from academics and key players in the pharmaceuticals industry.

Mendel Biotechnology Yield Trait Reaches Phase III For Monsanto Soybean Products (Medical News Today)
Monsanto Company ("Monsanto") announced earlier this week that it has advanced its higher yielding soybean trait, sourced from Mendel Biotechnology, Inc. ("Mendel"), into its Phase III development stage. The technology was identified and developed through a research program funded by Monsanto, designed to leverage Mendel's expertise in regulatory pathways and network biology.

Chinese Researchers Sequence World's First Giant Panda Genome (Medical News Today)
Illumina (NASDAQ: ILMN) announced that researchers at the Beijing Genomics Institute (BGI), Shenzhen are the first to complete de novo sequencing of the giant panda genome.

NHGRI to Fund Genomics ELSI Centers (GenomeWeb News)
NEW YORK (GenomeWeb News) — The National Human Genome Research Institute has set aside $3.9 million in funding for 2010 to create several cross-disciplinary centers that will study the ethical, legal, and social implications of genomics technologies.

KeyGene and Amplicon Express announce Whole Genome Profiling, a method that enables fast and efficient Whole Genome ... (SeedQuest)
The Whole Genome Profiling (WGP) method enables the de novo construction of a complete high quality physical map. This sequence-based physical map forms the framework to construct a complete genome sequence assembly of plant and animal genomes in a fast and cost-effective manner.

Abbott Licenses Rubicon's Methylation-Detection Tech (GenomeWeb News)
NEW YORK (GenomeWeb News) — Abbott has obtained a non-exclusive license to use Rubicon Genomics' MethylPlex methylation-detection technology, which it will use to develop in vitro diagnostics that detect presence or risk of prostate, bladder, and colon cancer, Rubicon said today.


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