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Bioinformatics News Jul 2008

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Scientists uncover proteins in seminal fluid that may affect odds of conceiving
Washington, July 29 : Scientists at the University of Washington (UW) have uncovered over 80 proteins in seminal fluid that can affect the likelihood of producing offspring. (Wed, 30 Jul 2008 05:02:02 GMT)

Defining DNA Differences To Track And Tackle Typhoid
For the first time, next-generation DNA sequencing technologies have been turned on typhoid fever -- a disease that kills 600,000 people each year. The study sets a new standard for analyzing the evolution and spread of a disease-causing bacterium: it is the first study of multiple samples of any bacterial pathogen at this level of detail. The results will help to improve diagnosis, tracking the ... (Wed, 30 Jul 2008 05:11:07 GMT)

Being A Control Freak Aids Dividing Cells
A dividing cell tags more than 14,000 different sites on its proteins with phosphate, a molecule that typically serves as a signal for a variety of biological processes. This preponderance of signals -- more than twice the number identified by past studies -- suggests that the cell may become a control freak during the division process, regulating each of its parts, no matter how obscure. ... (Wed, 30 Jul 2008 05:12:38 GMT)

Cruzado takes reins as interim
• To see a brief bio of Waded Cruzado, click here. To view a résumé, click here and for her list of priorities for NMSU, click here. (Wed, 30 Jul 2008 08:16:32 GMT)

New Frontiers In Single Cell Analysis
Since the advent of proteomics in the 1970-1980s and genomics in the 1990s, these disciplines have developed in ways that emphasize the rate and volume of data acquisition and analysis. (Wed, 30 Jul 2008 11:10:26 GMT)

New Future For Kiwifruit- Fruit Scientists Uncover DNA Behind Colour, Flavour, Shape, Nutrition And Ripening
Kiwifruit lovers can look forward to new, novel forms of their favourite fruit thanks to the release this week of crucial genetic data which fruit breeders say will help them naturally breed new varieties with increased health properties and exciting colours and flavours. (Wed, 30 Jul 2008 11:12:37 GMT)

Roche NimbleGen CGH Arrays Enable Detection of the Genomic Disorder Resulting in Diabetes
MADISON, Wis.----Chromosomal rearrangements leading to genomic disorders are often mediated by low-copy repeat regions of the genome . Roche NimbleGen CGH arrays offer expanded probe coverage in these regions. (Wed, 30 Jul 2008 12:00:00 GMT)

UCSF researchers identify virus behind mysterious parrot disease
Researchers at the University of California, San Francisco, have identified a virus behind the mysterious infectious disease that has been killing parrots and exotic birds for more than 30 years. (Wed, 30 Jul 2008 12:51:23 GMT)

Ludesi Introduces Low Cost 2D Gel Image Analysis Service "Ludesi Basic" to Meet Broader Market Demand
Ludesi Corporation, developer of the award-winning Ludesi Image Analysis Service for 2-dimensional electrophoresis gels, today announced "Ludesi Basic" -- a lightweight version of Ludesi's industry-leading 2D Gel Image Analysis Service that provides better data quality than conventional 2D gel software and comes at a $50.00 USD per gel price level that most researchers, institutions, and ... (Wed, 30 Jul 2008 13:15:00 GMT)

UC San Diego's GreenLight Project To Improve Energy Efficiency Of Computing
The GreenLight project gets its name from its plan to connect scientists and their labs to more energy-efficient 'green' computer processing and storage systems using photonics - light over optical fiber. (Wed, 30 Jul 2008 13:55:52 GMT)

Large study uncovers surprisingly diverse genome alterations that contribute to schizophrenia
A multinational group of investigators has discovered that people suffering from schizophrenia are far more likely to carry rare chromosomal structural changes of all types, particularly those that have the potential to alter gene function. (Wed, 30 Jul 2008 17:07:16 GMT)

deCODE and SGENE Consortium Discover Deletions in the Human Genome Linked to Risk of Schizophrenia
In a major paper published today in the online edition of the journal Nature, scientists from deCODE genetics and the University of Iceland, along with academic colleagues from the deCODE-led European SGENE consortium, China and the United States, report the discovery of three rare deletions in the human genome that confer risk of schizophrenia. (Wed, 30 Jul 2008 17:25:00 GMT)

New Research on Genetic Changes in Melanomas and Teens' Use of Indoor Tanning
Melanoma, the most serious form of skin cancer, accounts for more than 75 percent of all skin cancer deaths. Despite repeated health warnings based on proven science that overexposure to ultraviolet (UV) light is the most preventable cause of all skin cancers, including melanoma, many Americans are not properly protecting themselves from this known carcinogen. (Wed, 30 Jul 2008 17:28:15 GMT)

String probes for devastating childhood digestive disease
A swallowed string may someday replace the invasive, uncomfortable endoscope now used to diagnose eosinophilic esophagitis, a devastating childhood disease of the esophagus. (Wed, 30 Jul 2008 18:02:31 GMT)

System and Methods for Detecting and Characterizing Macromolecular Interactions in Solution
The present invention relates to systems and methods for sensitive detection and characterization of macromolecular interactions in homogenous or heterogeneous solutions of biological and/or synthetic macromolecules. (Wed, 30 Jul 2008 18:10:20 GMT)

Technology Review´s EmTech Conference to Gather Leading Technology Innovators and Entrepreneurs at MIT
Technology Review, Inc., the authority on the future of technology, today announced agenda highlights (Wed, 30 Jul 2008 19:01:20 GMT)

Technology Review's EmTech Conference to Gather Leading Technology Innovators and Entrepreneurs at MIT
Technology Review, Inc., the authority on the future of technology, today announced agenda highlights of its EmTech08 Conference, to be held September 23-25, 2008, on the MIT campus in Cambridge, Mass. Now in its eighth year, EmTech continues to provide a unique forum for exploring emerging technological innovations and their impact on business and society. (Wed, 30 Jul 2008 19:08:23 GMT)

String Probes for Devastating Childhood Digestive Disease
A swallowed string may someday replace the invasive, uncomfortable endoscope now used to diagnose eosinophilic esophagitis, a devastating childhood disease of the esophagus. (Wed, 30 Jul 2008 19:55:06 GMT)

Invitrogen Licenses Stem Cell Line from Buck Institute
CARLSBAD, Calif. & NOVATO, Calif.----Invitrogen Corporation , a provider of essential life science technologies for research, production and diagnostics, has licensed an engineered stem cell line from the Buck Institute for Age Research. (Wed, 30 Jul 2008 20:03:00 GMT)

Fertility: Newly Discovered Proteins In Seminal Fluid Transferred During Mating May Affect Odds Of Producing Offspring
More than 80 new proteins, thought to play a role in reproductive success, have been discovered in the seminal fluid of fruit flies. (Wed, 30 Jul 2008 20:09:47 GMT)

Engineer Taps Heat-Loving Bacteria for Hydrogen
A North Carolina State University engineer has been awarded a $1.6 million grant from the U.S. Department of Energy to learn more about the microbiology, genetics and genomics behind how and why heat-loving bacteria called thermotogales produce large amounts of hydrogen with unusually high efficiencies. These microorganisms are found all over the globe in areas which are naturally hot - ... (Wed, 30 Jul 2008 20:33:15 GMT)

Invitrogen Licenses Stem Cell Line from Buck Institute
Invitrogen Corporation (NASDAQ:IVGN), a provider of essential life science technologies for research, production and diagnostics, has licensed an engineered stem cell line from the Buck Institute for Age Research. The stem cell line is used in the study of neural cells in neurodegenerative disease. The financial terms were not disclosed. (Wed, 30 Jul 2008 20:34:52 GMT)

Business Beat: Weak dollar boosts biotech buyouts
There has been plenty of excitement on the local biotechnology scene, with three local start-ups acquired in the past 13 months. The most recent deal has the Swiss pharmaceutical company Roche Holdings paying $125 million for Madison-based Mirus Corp. Established in 1995 based on the gene therapy work of UW-Madison scientists, Mirus has about 60 total employees here who are expected to keep ... (Wed, 30 Jul 2008 22:25:56 GMT)

Join in a mass 'denimstration'
HUNTER New England Health is hosting a mass Denimstration this Friday, August 1 in the Manning and Great Lakes area, as part of the 50th birthday celebrations of the Children’s Medical Research Institute – which is the institute that benefits from us all wearing our jeans and buying a badge or t-shirt as part of Jeans 4 Genes Day. (Thu, 31 Jul 2008 00:35:26 GMT)

Berry & Associates signs supply agreement with Applied Biosystems
Berry & Associates has signed an agreement with Applied Biosystems to supply a key reagent for Applied Biosystemss genomic analysis platform, the SOLiD system. (Thu, 31 Jul 2008 00:38:27 GMT)

Cruzado takes reins as interim
• To see a brief bio of Waded Cruzado, click here. To view a résumé, click here and for her list of priorities for NMSU, click here. (Thu, 31 Jul 2008 02:15:16 GMT)

Deaths Draw Attention to Triathlon Swim
While triathlon deaths remain rare, a puzzling resemblance is beginning to present itself: all recorded deaths in the last two years have happened during the swim portion of the event. (Thu, 31 Jul 2008 05:13:03 GMT)

Cruzado takes reins as interim
• To see a brief bio of Waded Cruzado, click here. To view a résumé, click here and for her list of priorities for NMSU, click here. (Thu, 31 Jul 2008 06:02:56 GMT)

JBNI Releases 100 Percent Natural Herbal Medicines ('Herbal Foods' within USA) and Sports Formulas Challenging Public ...
The public's perception that Chinese Herbal Medicine is healthy but not dramatically effective has been building since the western introduction of Traditional Chinese Medicine's or TMC Herbal Medicine in the 1970's. (Thu, 31 Jul 2008 07:01:00 GMT)

Citizens' Inquiry calls for more public information and oversight of National DNA Database
The police National DNA Database should be placed under the control of an independent statutory authority, says the Human Genetics Commission . And there should be a vigorous nationwide information campaign to explain why DNA samples are taken, how they are used and why they are retained. (Thu, 31 Jul 2008 07:13:43 GMT)

MicroRNAs Tune Protein Synthesis
Researchers at the Max Delbruck Center for Molecular Medicine (MDC) Berlin-Buch, Germany, have generated new findings on how microRNAs (miRNA) regulate protein expression. Two teams lead by Matthias Selbach (Proteomics) and Nikolaus Rajewsky (Systems Biology) have shown that a single miRNA can directly regulate synthesis of hundreds of different proteins. (Thu, 31 Jul 2008 08:09:37 GMT)

Illumina to Present at the Leerink Swann Life Science Tools Roundtable Conference
SAN DIEGO----Illumina, Inc. announced today that the Company will webcast its presentation at the Leerink Swann Life Science Tools Roundtable Conference on Thursday, August 7, 2008 in New York, NY. (Thu, 31 Jul 2008 10:00:00 GMT)

Ore Pharmaceuticals Acquires Repositioned Clinical-Stage Drug Candidate from Roche
GAITHERSBURG, Md.----Ore Pharmaceuticals Inc. announced today that it has acquired from Roche the clinical-stage compound tiapamil. Ore Pharmaceuticals had previously identified potentially novel therapeutic uses for tiapamil in central nervous system disease and recently filed for patent protection regarding the use of the compound. (Thu, 31 Jul 2008 10:00:00 GMT)

DeCODE And SGENE Consortium Discover Deletions In The Human Genome Linked To Risk Of Schizophrenia
In a major paper published in the online edition of the journal Nature, scientists from deCODE genetics (Nasdaq: DCGN) and the University of Iceland, along with academic colleagues from the deCODE-led European SGENE consortium, China and the United States, report the discovery of three rare deletions in the human genome that confer risk of schizophrenia. (Thu, 31 Jul 2008 10:11:17 GMT)

Endoscope May Be Replaced By String Probe To Detect Devastating Childhood Digestive Disease
A swallowed string may someday replace the invasive, uncomfortable endoscope now used to diagnose a devastating childhood disease of the esophagus. Steven J. Ackerman of University of Illinois at Chicago College of Medicine and Dr. Glenn T. (Thu, 31 Jul 2008 12:10:06 GMT)

Affymetrix Microarray Platform Granted Clearance from FDA for Gene Expression Diagnostic Testing
SANTA CLARA, Calif.----Affymetrix Inc. announced today that the U.S. Food and Drug Administration has granted regulatory clearance to its GCS3000Dx platform for in vitro gene expression diagnostic testing. (Thu, 31 Jul 2008 13:00:00 GMT)

Affymetrix gets FDA clearance for gene expression diagnostic testing
Affymetrix Inc.'s produt for in vitro gene expression diagnostic tesing has been given regulatory clearance by the U.S. Food and Drug Administration, the company said Thursday. (AFFX) (Thu, 31 Jul 2008 13:32:22 GMT)

FDA Clears Test that Helps Identify Type of Cancer in Tumor Sample
The U.S. Food and Drug Administration has cleared for marketing a test that can help health care professionals determine what type of cancer cells are present in a malignant tumor. The Pathwork Tissue of Origin test compares the genetic material of a patient's tumor with genetic information on malignant tumor types stored in a database. (Thu, 31 Jul 2008 13:51:45 GMT)

Affymetrix to Webcast Presentation at Leerink Swann Life Sciences Tools Conference
SANTA CLARA, Calif.----Affymetrix, Inc. today announced that Stephen P.A. Fodor, Ph.D., Chairman and Chief Executive Officer, will provide a company overview at the Leerink Swann Life Science Tools Roundtable Conference on August 7, 2008 in New York City, NY. (Thu, 31 Jul 2008 14:00:00 GMT)

Illumina to Present at the Leerink Swann Life Science Tools Roundtable Conference
Illumina, Inc. (NASDAQ:ILMN) announced today that the Company will webcast its presentation at the Leerink Swann Life Science Tools Roundtable Conference on Thursday, August 7, 2008 in New York, NY. The live webcast is scheduled to begin at 10:40am ET and will feature a discussion with Jay Flatley, President and Chief Executive Officer, about the Company's commercial and product development ... (Thu, 31 Jul 2008 14:24:17 GMT)

Mom's Alzheimer's May Raise Children's Risk
Adult kids of moms with late-onset Alzheimer's disease may be more likely to have brain metabolism changes tied to Alzheimer's, new research shows. (Thu, 31 Jul 2008 15:00:05 GMT)

FDA has cleared the The Pathwork Tissue of Origin test
Not all breast tumors are the same. Nor are all bladder tumors. Nor are all colorectal tumors. Yet medicine has considered them such for years. Treatments have focused on which organ the tumor resides in, yet we know that no single treatment works for all tumors found in a certain organ. (Thu, 31 Jul 2008 15:14:22 GMT)

FDA approves tumor identification test
WASHINGTON, July 31 (UPI) -- The U.S. Food and Drug Administration has approved a test that can identify cancer cells contained within a malignant tumor. (Thu, 31 Jul 2008 15:23:41 GMT)

FDA approves tumor identification test
The U.S. Food and Drug Administration has approved a test that can identify cancer cells contained within a malignant tumor.The FDA said the Pathwork Tissue of Origin test compares the genetic material of a patient's tumor with genetic information on malignant tumor types stored in a database. It uses a microarray technology to analyze thousands of pieces of genetic material at one time. The ... (Thu, 31 Jul 2008 15:34:57 GMT)

Affymetrix Microarray Platform Granted Clearance from FDA for Gene Expression Diagnostic Testing
Affymetrix Inc. (Nasdaq:AFFX) announced today that the U.S. Food and Drug Administration (FDA) has granted regulatory clearance to its GCS3000Dx (GCSDx) platform for in vitro gene expression diagnostic testing. The microarray system was granted clearance along with the Pathwork(R) Tissue of Origin (TOO) Test from Pathwork Diagnostics Inc. This test analyzes a tumor's gene expression profile to ... (Thu, 31 Jul 2008 15:39:26 GMT)

FDA clears new cancer test
The U.S. Food and Drug Administration has cleared for marketing a test that can help health care professionals determine what type of cancer cells are present in a malignant tumor. (Thu, 31 Jul 2008 16:02:20 GMT)

Recent Triathlon Deaths Have Experts Searching for Answers
While triathlon deaths remain rare, a puzzling resemblance is beginning to present itself: all recorded deaths in the last two years have happened during the swim portion of the event. (Thu, 31 Jul 2008 16:08:51 GMT)

Invitrogen Licenses Stem Cell Line From Buck Institute
Invitrogen Corporation (NASDAQ:IVGN), a provider of essential life science technologies for research, production and diagnostics, has licensed an engineered stem cell line from the Buck Institute for Age Research (Thu, 31 Jul 2008 16:10:42 GMT)

Affymetrix to Webcast Presentation at Leerink Swann Life Sciences Tools Conference
Affymetrix, Inc. (Nasdaq:AFFX) today announced that Stephen P.A. Fodor, Ph.D., Chairman and Chief Executive Officer, will provide a company overview at the Leerink Swann Life Science Tools Roundtable Conference on August 7, 2008 in New York City, NY. A live webcast of the presentation will take place at 1:30 p.m. ET. (Thu, 31 Jul 2008 16:11:13 GMT)

FDA approves Affymetrix gene expression diagnostic testing
Affymetrix Inc. 's product for in vitro gene expression diagnostic tesing has been given regulatory clearance by the U.S. Food and Drug Administration, the company said Thursday. (AFFX) (Thu, 31 Jul 2008 16:49:24 GMT)

J. Craig Venter Institute Launches New Genomics Education Program in California
Program will give San Diego area teachers in-depth information about exciting advances in genomics (Thu, 31 Jul 2008 16:56:00 GMT)

Plant Breeding Electronic Journal Club
The GIPB Knowledge Resource Center is launching the , a virtual place that allows communities to meet and critically evaluate plant breeding and related fields' articles in the scientific literature. (Thu, 31 Jul 2008 17:06:10 GMT)

Washington, DC July 31, 2008
Agriculture Under Secretary for Research, Education and Economics Gale Buchanan and Energy Department (DOE) Under Secretary for Science Raymond Orbach and today announced plans to award 10 grants totaling more than $10 million to accelerate fundamental research in the development of cellulosic biofuels. (Thu, 31 Jul 2008 17:06:54 GMT)

July, 2008
The Plant Genome is an international open-access electronic journal published by the Crop Science Society of America . The goal of The Plant Genome is to provide the readership with a short submission-to-online publication of the latest advances and breakthroughs in plant genomics research. (Thu, 31 Jul 2008 17:07:09 GMT)

Viterbi Algorithm goes quantum
The Viterbi Algorithm, the elegant 41-year-old logical tool for rapidly eliminating dead end possibilities in data transmission, has a new application to go alongside its ubiquitous daily use in cell phone communications, bioinformatics, speech recognition and many other areas of information technology. (Thu, 31 Jul 2008 19:47:12 GMT)

DOE, USDA Granting More Than $10M to Ten Biofuel Genomics Studies
GenomeWeb Daily News You are not logged in. Existing subscribers login here . New to GenomeWeb Daily News? Register quickly here for your free subscription. (Thu, 31 Jul 2008 19:55:33 GMT)

Strategic Diagnostics Reports Second Quarter 2008 Results
NEWARK, Del.----Strategic Diagnostics Inc. - a leading provider of biotechnology-based detection solutions for a broad range of food, water, agricultural, industrial, environmental and scientific applications, today reported financial results for the quarter and six months ended June 30, 2008. (Thu, 31 Jul 2008 20:00:00 GMT)

Strategic Diagnostics Reports Second Quarter 2008 Results
Strategic Diagnostics Inc. (NASDAQ: SDIX) - a leading provider of biotechnology-based detection solutions for a broad range of food, water, agricultural, industrial, environmental and scientific applications, today reported financial results for the quarter and six months ended June 30, 2008. Revenues for the quarter decreased 2% to $6.6 million, compared to $6.7 million for the same period in ... (Thu, 31 Jul 2008 20:24:24 GMT)

Deaths Draw Attention to Triathlon Swim
While triathlon deaths remain rare, a puzzling resemblance is beginning to present itself: all recorded deaths in the last two years have happened during the swim portion of the event. (Thu, 31 Jul 2008 21:52:51 GMT)

FDA clears test that determines what type of cancer cells are present in a malignant tumor
The U.S. Food and Drug Administration has cleared for marketing a test that can help health care professionals determine what type of cancer cells are present in a malignant tumor. (Thu, 31 Jul 2008 22:40:38 GMT)

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