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Bioinformatics News 07/2008

Migraine Mutations Reveal Clues To Biological Basis Of Disorder (Science Daily)
By studying a rare, inherited form of migraine, researchers at Vanderbilt University Medical Center have found clues to the biological basis of the painful, debilitating disorder.

New Electrostatic-based DNA Microarray Technique Could Revolutionize Medical Diagnostics (Science Daily)
Researchers have invented a technique in which DNA assays -- the key to personalized medicine -- can be read and evaluated with no need of elaborate chemical labeling or sophisticated instrumentation. Based on electrostatic repulsion that yields images visible to the naked eye, the technique could revolutionize the use of DNA microarrays for both research and diagnostics.

QIAGEN Acquires Corbett Life Science (PrimeNewswire via Yahoo! Finance)
VENLO, The Netherlands, July 1, 2008 -- QIAGEN N.V. today announced that it has acquired Corbett Life Science Pty. Ltd. , a privately-held developer, manufacturer, and distributor of life sciences instrumentation headquartered in Sydney, Australia.

QIAGEN Acquires Corbett Life Science (Fox News)
Transaction Adds Proprietary Real-Time PCR Detection Technologies to QIAGEN's Portfolio of Molecular Testing Solutions

01.07.2008 - DJ HUGIN NEWS/QIAGEN Acquires Corbett Life Science (4investors)
Corporate news announcement processed and transmitted by Hugin ASA. The issuer is solely responsible for the content of this announcement. =----------------------------- =-------------

Clinical Data Secures EU Patent For MDR1 - A Key Multi-Drug Resistance Gene (Medical News Today)
Clinical Data, Inc. (NASDAQ: CLDA), a leader in the development of targeted therapeutics and predictive tests from its growing portfolio of proprietary genetic biomarkers, announced today that the European Patent Office has granted Patent No.

Migraine Mutations Reveal Clues To Biological Basis Of Disorder (Medical News Today)
Fifteen percent to 20 percent of people worldwide suffer from migraines excruciating headaches often presaged by dramatic sensations, or "auras." By studying a rare, inherited form of migraine, researchers at Vanderbilt University Medical Center have found clues to the biological basis of the painful, debilitating disorder.

SIRS-Lab Pre-Announces Biomarker Based Sepsis Test (Business Wire via Yahoo! Finance)
JENA, Germany----SIRS-Lab introduces a new diagnostic concept for the early prediction and reliable monitoring of sepsis. The molecular diagnostic test “SIQNATURE” delivers the earliest possible information about the potential development of a systemic infection.

Simple method may revolutionise genetic profiling, disease detection (New Kerala)
London, July 1 : Researchers at the U.S. Department of Energy's Lawrence Berkeley National Laboratory (Berkeley Lab) claim to have invented a simple and inexpensive method for reading DNA (or RNA) microarrays within minutes.

The Wellcome Trust Case Control Consortium (WTCCC) Selects Illumina Infinium High-Density (HD) DNA Analysis Products ... (Business Wire via Yahoo! Finance)
SAN DIEGO----Illumina, Inc. today announced that researchers participating in a new initiative funded by the Wellcome Trust selected Illumina's Infinium HD BeadChips to analyze 90,000 DNA samples.

Migraines linked to genetic mutations (New Kerala)
Washington, July 1 : Researchers from Vanderbilt University Medical Centre have revealed that migraines might be linked to genetic mutations.

Ore Pharmaceuticals Files Investigational New Drug Application with FDA (Centre Daily Times)
Ore Pharmaceuticals Inc. (NASDAQ:ORXE) announced today that it has filed an investigational new drug (IND) application with the U.S. Food and Drug Administration (FDA) for GL1001, the first clinical-stage inhibitor of the ACE2 enzyme. This orally administered small molecule is being developed primarily for inflammatory bowel disease (IBD). Treatment with GL1001 has decreased several disease ...

The Wellcome Trust Case Control Consortium (WTCCC) Selects Illumina Infinium High-Density (HD) DNA Analysis Products ... (Centre Daily Times)
Illumina, Inc. (NASDAQ:ILMN) today announced that researchers participating in a new initiative funded by the Wellcome Trust selected Illumina's Infinium HD BeadChips to analyze 90,000 DNA samples. This new initiative aims to decipher the molecular basis of human disease and includes participation from leading research groups around the globe. Together, researchers at the Wellcome Trust Case ...

Duke offers free health seminars in Kannapolis (The Salisbury Post)
By Emily Ford [email protected] KANNAPOLIS — Residents will meet the scientists who will study this city for the next several years when Duke ...

The Wellcome Trust Case Control Consortium (WTCCC) Selects Illumina Infinium High-Density (HD) DNA Analysis Products ... (Fox News)
The Wellcome Trust Case Control Consortium (WTCCC) Selects Illumina Infinium High-Density (HD) DNA Analysis Products to Study 90,000 Samples

New DNA Microarray Technique Based on Electrostatics (AnandTech)
Detecting specific genes and pathogens in DNA and RNA is typically quite expensive and time consuming. But that's about to change....

State officially launches the ECMC-Kaleida consolidation (The Buffalo News)
The state signed on Monday as an enthusiastic supporter of the plan to combine Kaleida Health and Erie County Medical Center under one administration, with Dr. Richard F. Daines, state health commissioner, the top cheerleader.

Researchers Are First To Simulate The Binding Of Molecules To A Protein (Medical News Today)
You may not know what it is, but you burn more than your body weight of it every day. Adenosine triphosphate (ATP), a tiny molecule that packs a powerful punch, is the primary energy source for most of your cellular functions. Now researchers at the University of Illinois have identified a key step in the cellular recycling of ATP that allows your body to produce enough of it to survive.

Pacific Rim Summit Will Showcase Advanced Biotech Tools for Renewable Fuels and Chemicals (ThomasNet)
At Pacific Rim Summit, scheduled for Sept 10-12 in Vancouver, research scientists and industry leaders will present progress in developing advanced biotech fuels and chemicals through genomics, synthetic biology, and genetic engineering. Scheduled plenary speaker, Drew Endy, Assistant Professor of Bioengineering at Stanford University, will discuss how new understanding of genomic information is ...

Hybrigenics And Dualsystems Enter Into Strategic Partnership For Yeast Two-Hybrid Screens Of Full Membrane Proteins (BioresearchOnline)
Hybrigenics, a listed bio-pharmaceutical company with a focus on research and development of new cancer treatments and specialized in protein interactions, announced that it has formed a strategic partnership to complement Hybrigenics' portfolio with Dualsystems' DUALmembrane yeast two-hybrid technology especially designed for full membrane proteins

Supercomputer Used To Track Pathways In Myoglobin (Medical News Today)
Some 50 years ago, after decades of effort, John Kendrew determined the structure of the small globular protein, myoglobin, which is responsible for oxygen storage in cells. For this discovery, he shared the Nobel Prize in chemistry with Max Perutz, who did similar work on hemoglobin.

BioTrove, Gene Express Awarded NIH Grant to Develop Novel Standardized Genetic Profiling Test (Centre Daily Times)
BioTrove, Inc. and Gene Express, Inc. today announced their receipt of a two-year National Institutes of Health (NIH) grant, awarded in support of their proposed novel research of genetic biomarkers for lung cancer. Part of the NIH competitive grant program "Innovative Technologies for Molecular Analysis of Cancer," the project will combine for the first time BioTrove's OpenArray(TM) nanofluidic ...

Medical Diagnostics Could Be Revolutionized By New Electrostatic-Based DNA Microarray Technique (Medical News Today)
The dream of personalized medicine - in which diagnostics, risk predictions and treatment decisions are based on a patient's genetic profile - may be on the verge of being expanded beyond the wealthiest of nations with state-of-the-art clinics. A team of researchers with the U.S.

Celera makes split official, moves to California (BizJournals)
Celera Corp. has separated from its parent company and ended its run as a high-flying local biotech. (CRA)

Celera makes split official, moves to California (BizJournals)
Celera Corp. has separated from its parent company and ended its run as a high-flying local biotechnology firm. (CRA) (OFC)

IBT Laboratories Names Maureen Loftus President and Chief Operating Officer (PR Newswire via Yahoo! Finance)
IBT Laboratories, a leading global clinical-diagnostics and biomedical-research laboratory specializing in immunology and allergy assays, announced that Maureen Loftus has joined the company as president and chief operating officer.

State officially launches the ECMC-Kaleida consolidation (The Buffalo News)
The state signed on Monday as an enthusiastic supporter of the plan to combine Kaleida Health and Erie County Medical Center under one administration, with Dr. Richard F. Daines, state health commissioner, the top cheerleader.

Genomics Research Focuses on Rice Variety Improvement (PhysOrg)
Crop varieties can be improved through the study of genomics without creating genetically transformed varieties. That is the mission of a multistate research project led by the University of Arkansas System`s Division of Agriculture.

Pediatric researchers find possible 'master switch' gene in juvenile arthritis (EurekAlert!)
PHILADELPHIA, July 1, 2008 – Researchers have found that a gene region known to play a role in some varieties of adult rheumatoid arthritis is also present in all types of childhood arthritis.

Fungi the cause of many outbreaks of disease but mostly ignored (EurekAlert!)
There is a serious lack of scientific data to support any stance with respect to indoor mold toxicity or remediation. More effort should be devoted to testing and long-term monitoring of mold contamination and human health in New Orleans and other areas flooded by Hurricane Katrina.

Frontiers in Psychiatric Research (Psychiatric Times)
These are exciting times for genetics research: Science magazine chose our new appreciation of human genetic diversity as the scientific breakthrough of the year 2007. 1 The year brought a new genetic bonanza with the announcement of the 1000 Genome Project, a plan to capture human diversity by obtaining the entire genome sequence information of 1000 individuals.

Addiction Research and Treatment (Psychiatric Times)
The nation's leading causes of death are related to alcohol and drug use, tobacco smoke exposure, and behavioral addictions. Each year, more than 400,000 Americans die as a result of smoking, overeating, substance use, and related accidents and suicide.

Relaxation response can influence expression of stress-related genes (EurekAlert!)
How could a single, nonpharmacological intervention help patients deal with disorders ranging from high blood pressure, to pain syndromes, to infertility, to rheumatoid arthritis?

Designer diet for prostate cancer (EurekAlert!)
For the first time, a research group at the Institute of Food Research led by Professor Richard Mithen has provided an explanation of how eating broccoli might reduce cancer risk based upon studies in men, as opposed to trying to extrapolate from animal models. Prostate cancer is the most common non-skin cancer for males in western countries. The research has provided an insight into why eating ...

Designer diet for prostate cancer (News-Medical-Net)
Eating one or more portions of broccoli every week can reduce the risk of prostate cancer, and the risk of localised cancer becoming more aggressive.

BioWorld International Correspondent (BioWorld)
BRUSSELS, Belgium - There is a slowdown in the volume of useful new drugs on the European market, and biotech is in part to blame, according to the leading European pharmaceutical industry association.

Waters India to tap proteomics research prospects with its package of solutions (PharmaBiz)
Waters India is now is aggressively pursuing opportunities to expand its proteomics business in the country.

Footrot vaccine closer than ever (EurekAlert!)
Monash University scientists have started clinical trials to find a successful vaccine against footrot in sheep.

DNA Technology Posts Exponential Speed Increases (Wired News)
A prominent genetics research facility, the Wellcome Trust Sanger Institute, recently sequenced its trillionth base pair of DNA, illustrating the exponential increases in speed that new DNA sequencers have made possible.

Search begins for new UA vice president (The Arizona Republic)
The medical school's dean is set to resign.

Sequenom Launches iSEQ Application (Business Wire via Yahoo! Finance)
SAN DIEGO----Sequenom, Inc. , a leading provider of genetic analysis solutions, today announced the launch of the iSEQ™ application software, a MassARRAY® comparative sequence analysis application for automated, high-throughput identification and typing of microbes and viruses, as well as human disease-related molecular markers.

Sequenom Launches iSEQ Application (Centre Daily Times)
Sequenom, Inc. (NASDAQ: SQNM), a leading provider of genetic analysis solutions, today announced the launch of the iSEQ(TM) application software, a MassARRAY(R) comparative sequence analysis application for automated, high-throughput identification and typing of microbes and viruses, as well as human disease-related molecular markers. This product is directed toward the infectious disease market ...

New High-Tech Imaging Center "TIGA" At The University Of Heidelberg / Robot "NanoZoomer" Shows High-Resolution Images ... (Medical News Today)
"TIGA," the new high-tech imaging center at the University of Heidelberg founded in cooperation with the Japanese company Hamamatsu, provides deep insights: a high-tech robot makes it possible for the first time to automatically reproduce and evaluate tissue slices only micromillimeters thick - an im

Massachusettsfirm purchases Open Biosystems (The Huntsville Times)
Open Biosystems, one of Huntsville's leading biotechnology companies, has been acquired by Thermo Fisher Scientific in Massachusetts. Open Biosystems, based at the HudsonAlpha Institute for Biotechnology, produces genomic research tools.

Designer diet for prostate cancer (PhysOrg)
Eating one or more portions of broccoli every week can reduce the risk of prostate cancer, and the risk of localised cancer becoming more aggressive.

Eating broccoli can reduce prostate cancer risk (New Kerala)
Washington, July 2 : Eating a broccoli-rich diet can reduce the risk of deadly prostate cancer, according to researchers.

Footrot vaccine closer than ever (PhysOrg)
Monash University scientists have started clinical trials to find a successful vaccine against footrot in sheep.

Relaxation response can influence expression of stress-related genes (PhysOrg)
How could a single, nonpharmacological intervention help patients deal with disorders ranging from high blood pressure, to pain syndromes, to infertility, to rheumatoid arthritis? That question may have been answered by a study finding that eliciting the relaxation response - a physiologic state of deep rest - influences the activation patterns of genes associated with the body's response to ...

Eating broccoli can reduce cancer risk 2 Jul 2008, 1546 hrs IST,ANI (The Times of India)
WASHINGTON: Eating a broccoli-rich diet can reduce the risk of deadly prostate cancer, according to researchers. What's more, the consumption of one or more portions of the green veggie can lessen the risk of localized cancer becoming more aggressive.

VLST Corporation Appoints Internationally Recognized Researcher Paul J. Carter, Ph.D. as Chief Scientific Officer (Business Wire via Yahoo! Finance)
SEATTLE----VLST Corporation, a Seattle-based biotechnology company focused on the development of therapeutics for autoimmune and inflammatory disorders, today announced that Paul J.


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