Bioinformatics News Apr 2008: bioinformatics, genomics, proteomics, microarray, etc.

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Gene-environment Interaction In Yeast Gene Expression
Researchers have shown that gene-environment interaction is a common phenomenon in the regulation of gene expression. In a new study, they describe how different classes of genetic variants affect the nature of the interactions, and provide detailed molecular examples of interactions. (Mon, 14 Apr 2008 13:22:59 GMT)

Roswell Park's Norma Nowak, PhD, Part of the Award Winning Team
Norma J. Nowak, PhD, a nationally recognized leader in genomic technology and cancer genetics research at Roswell Park Cancer Institute (RPCI), joined colleagues from the University of California, San Francisco, Comprehensive Cancer Center and Lawrence Berkeley National Laboratory in accepting the AACR Team Science Award at the 2008 annual meeting of the American Association for Cancer Research ... (Mon, 14 Apr 2008 13:26:16 GMT)

Power3 Medical Products Receives CLIA Compliance Recertification
Power3 Medical Products, Inc. (OTCBB: PWRM, https://www.power3medical.com) a leading proteomics company specializing in the development and commercialization of diagnostic tests for the early detection of breast cancer and neurodegenerative diseases, has received its CLIA compliance recertification following a CLIA regulatory inspection. (Mon, 14 Apr 2008 13:48:48 GMT)

Method To Deliver Molecules Within Embryonic Stem Cells Improves Differentiation
New research shows that delivering molecules within aggregates of embryonic stem cells via biodegradable microspheres enhances the efficiency and purity of differentiation. (Mon, 14 Apr 2008 14:07:59 GMT)

Rosetta Genomics Signs Agreement With West Coast CLIA Certified Lab To Develop And Validate Tests Applying Company's ...
Rosetta Genomics, Ltd., a leader in the development of microRNA-based diagnostic and therapeutic products, announced it has signed an agreement with University of California, Irvine School of Medicine (UC Irvine), relating to the development and validation of diagnostic tests based on the company's microRNA technology (Mon, 14 Apr 2008 14:28:48 GMT)

SeqWright Expands Next Generation Lineup With The Addition Of 454's GS FLX System
SeqWright Inc., a leading Genomics CRO, has added 454's GS FLX system to increase the breadth of its next generation offerings and to provide genomic researchers with more cost effective genomics solutions (Mon, 14 Apr 2008 14:28:58 GMT)

UC Irvine to Validate MicroRNA Dx Tests for Rosetta Genomics
GenomeWeb Daily News You are not logged in. Existing subscribers login here . New to GenomeWeb Daily News? Register quickly here for your free subscription. (Mon, 14 Apr 2008 14:51:13 GMT)

(AFX UK Focus) 2008-04-14 16:05 GMT: TFN NEWS BRIEFING: Mergers and acquisitions highlights to 15:50 BST
2008-04-14 15:37:49 Blockbuster offers to buy Circuit City (Mon, 14 Apr 2008 15:23:12 GMT)

Keynote Panel at Bio-IT World Expo to Feature Six Leaders in the Field of "Personal Genomics"
A plenary panel discussion on the exciting field of "personal genomics," featuring six of the most outstanding scientists, physicians and commentators in the field, is among the highlights of the 2008 Bio-IT World Conference & Expo being held April 28 - 30 at the World Trade Center in Boston. (Mon, 14 Apr 2008 15:30:00 GMT)

febit First to Offer miRBase 11.0 Biochip
febit today announced its newest miRNA Biochip based on the new miRBASE version 11.0 which has been released by the Wellcome Trust Sanger Institute yesterday. The new Geniom® Biochip opens up the most up-to-date scientific information for miRNA microarray experiments. (Mon, 14 Apr 2008 15:40:00 GMT)

Genome scans go deep into your DNA
Dad's cholesterol? Grandma's hypertension? Extensive genetic scans can tell us who we really are inside. However, there is such a thing as TMI. MY MATERNAL grandmother had Alzheimer's disease. Before she died, she forgot our names, our faces and, eventually, how to speak and think. But my grandfather's heartbreak was the most painful to witness. I remember watching the two of them on the sofa ... (Mon, 14 Apr 2008 16:51:40 GMT)

Tomato pathogen genome may offer clues about bacterial evolution
The availability of new genome sequencing technology has prompted a Virginia Tech plant scientist to test an intriguing hypothesis about how agriculture`s early beginnings may have impacted the evolution of plant pathogens. (Mon, 14 Apr 2008 20:12:40 GMT)

Blood urate levels associated with the progression of Parkinson's disease
Higher blood levels of the compound urate, a salt derived from uric acid that is associated with gout, may be associated with a slower progression of Parkinson's disease, according to an article posted online today that will appear in the June 2008 print issue of Archives of Neurology, one of the JAMA/Archives journals. (Mon, 14 Apr 2008 20:17:15 GMT)

Affymetrix Announces Preliminary First Quarter Revenue
Affymetrix, Inc. (Nasdaq:AFFX), today reported that based on preliminary financial data, the Company expects total revenue for the first quarter of 2008 to be approximately $170 million, including an intellectual property payment of $90 million received by the Company in connection with a previously announced settlement of patent litigation. (Mon, 14 Apr 2008 20:29:47 GMT)

Buck Institute and Q Therapeutics Form Stem Cell Collaboration to Combat Parkinson's Disease
The Buck Institute for Age Research and Q Therapeutics, Inc. announced today an agreement to collaborate on novel routes to combat Parkinson's disease. (Mon, 14 Apr 2008 21:00:06 GMT)

AVEO Pharmaceuticals' Novel Triple VEGF Receptor Inhibitor Shows Tumor Regression in Patients with Advanced Renal ...
AVEO Pharmaceuticals, Inc., a biotechnology company leveraging breakthrough discoveries in cancer biology to discover, develop and commercialize targeted oncology therapies, today announced that their novel oral triple VEGF receptor inhibitor AV-951 shows clinical activity in multiple advanced solid tumor types including renal, colon and lung cancers and is well tolerated according to new data ... (Mon, 14 Apr 2008 22:14:15 GMT)

AVEO Pharmaceuticals´ Novel Triple VEGF Receptor Inhibitor Shows Tumor Regression in Patients with Advanced Renal ...
AVEO Pharmaceuticals, Inc., a biotechnology company leveraging breakthrough discoveries in cancer (Mon, 14 Apr 2008 22:19:41 GMT)

ChemGenex Reports Oral Bioavailability of Omacetaxine and Expands on Mechanism of Action
ChemGenex Pharmaceuticals Limited (ASX:CXS) (NASDAQ:CXSP) announced today that pre-clinical data characterizing the bioavailability and mechanism of action of omacetaxine mepesuccinate (formerly known as Ceflatonin(R)) were presented on Monday local time at the American Association of Cancer Research (AACR) 99th Annual Meeting in San Diego, California. (Mon, 14 Apr 2008 23:00:00 GMT)

TRADE NEWS: Agilent's Stratagene Announces Expanded Line of QPCR, QRT-PCR Reagents at American Association for Cancer ...
SAN DIEGO----Stratagene, an Agilent Technologies Inc. company, announced today it has launched an expanded line of quantitative PCR reagents with enhanced sensitivity of detection. This new line of Brilliant II QPCR and QRT-PCR reagents was developed specifically to provide improved performance on the Stratagene Mx systems. (Mon, 14 Apr 2008 23:47:00 GMT)

New insights into the genetic basis of resistance to chemotherapy in children with acute leukemia
In a new study published in PLoS Medicine, William Evans of St Jude Children’s Research Hospital, Memphis, and colleagues provide new insight into resistance to the widely-used cancer drug methotrexate (MTX) in patients with acute lymphoblastic leukaemia (ALL), the most common cancer in children. (Tue, 15 Apr 2008 00:13:46 GMT)

TRADE NEWS: Agilent's Stratagene Announces Expanded Line of QPCR, QRT-PCR Reagents at American Association for Cancer ...
Stratagene, an Agilent Technologies Inc. (NYSE:A) company, announced today it has launched an expanded line of quantitative PCR reagents with enhanced sensitivity of detection. This new line of Brilliant II QPCR and QRT-PCR reagents was developed specifically to provide improved performance on the Stratagene Mx systems. The launch of Brilliant II is the first major product introduction by ... (Tue, 15 Apr 2008 00:14:04 GMT)

Skin Cancer Breakthrough? New Molecule Shows Promise In Patients With Advanced Basal Cell Carcinoma
A novel molecule, GDC-0449, shrinks tumors for patients with advanced basal cell carcinoma with limited side effects, suggesting a viable new treatment option for patients with the advanced form of this cancer. "Basal cell carcinoma affects about one million people a year, and a very small fraction of these patients have disease that is not curable with surgery. We currently do not have any ... (Tue, 15 Apr 2008 04:25:50 GMT)

Lawmaker Urges Passage of Tobacco Regulation Bill
A New York lawmaker is calling on Congress to pass legislation that would further regulate how tobacco products are sold and marketed to children. Rep. Vito Fossella, a Republican of Staten Island, along with representatives from the American Cancer Society, lobbied on behalf of the legislation, which would ban the sale of cigarettes to children, restrict marketing targeting children, ban fruit- ... (Tue, 15 Apr 2008 06:19:06 GMT)

San Francisco
SAN DIEGO , April 15 /PRNewswire-FirstCall/ -- Systems Medicine LLC (SM), a wholly owned subsidiary of Cell Therapeutics, Inc. (CTI) (Nasdaq and MTAX: CTIC ), presented data from a preclinical study demonstrating that the Company's experimental drug candidate, brostallicin, killed colon and ovarian cancer cells regardless of their p53 status. (Tue, 15 Apr 2008 06:25:44 GMT)

New Gene Discovery Suggests Which Patients CTI's Brostallicin May Benefit
Systems Medicine LLC (SM), a wholly-owned subsidiary of Cell Therapeutics, Inc. (CTI) (Nasdaq and MTAX: CTIC), presented data from a preclinical study identifying the genetic markers in patients more likely to respond to treatment with the experimental drug, brostallicin, at the 2008 American Association for Cancer Research (AACR) annual meeting. (Tue, 15 Apr 2008 08:15:45 GMT)

MWG Biotech Purchases Second Genome Sequencer FLX System to Expand Capacities in Line with Growing Sequencing Demand
454 Life Sciences, a centre of excellence of Roche Applied Science, today announced that MWG Biotech, a European market leader in genome sequencing services, is further expanding its 454 Sequencing capacity in order to meet the demands of a steadily increasing number of sequencing customers across Europe. (Tue, 15 Apr 2008 09:29:14 GMT)

AltheaDx Named Affymetrix Authorized Service Provider
AltheaDx, a leading provider of contract testing services to the pharmaceutical and biotechnology industry, today announced a supply and service provider agreement with Affymetrix Inc. (NASDAQ: AFFX). The agreement enables AltheaDx to offer complete biomarker discovery and development services based on the Affymetrix GeneChip® microarray platform. (Tue, 15 Apr 2008 10:00:00 GMT)

Portsmouth area community calendar
Portsmouth (Tue, 15 Apr 2008 10:09:34 GMT)

New Molecule Shows Promise In Patients With Advanced Basal Cell Carcinoma
A novel molecule, GDC-0449, shrinks tumors for patients with advanced basal cell carcinoma with limited side effects, suggesting a viable new treatment option for patients with the advanced form of this cancer, according to research presented at the 2008 Annual Meeting of the American Association for Cancer Research. (Tue, 15 Apr 2008 10:14:14 GMT)

The Scripps Translational Science Institute Joins The MetaMiner Cardiac Consortium
GeneGo, Inc., the leading systems biology tools company, announced today that The Scripps Translational Science Institute has joined the MetaMiner Cardiac Consortium. The goal of the Consortium is to build the first systems biology and pathway analysis platform for cardiovascular diseases in the world. (Tue, 15 Apr 2008 11:00:00 GMT)

Calibrant Biosystems Announces Appointment of Dr. Satya Saxena as Vice-President of Research
GAITHERSBURG, Md.----Calibrant Biosystems today announced the appointment of Dr. Satya Saxena as its Vice-President of Research. Dr. Saxena will lead Calibrant's proteomic technology and product development programs. (Tue, 15 Apr 2008 11:30:00 GMT)

Biotherapy, a new wave of medicine for cancer treatment
The doctor’s pronouncement of cancer still strikes fear in people’s hearts like few other diseases do. And with good reason. After all, cancer is caused by the abnormal and uncontrolled division of the body’s own cells and despite unparalleled advancements in medicine, is often a death sentence. (Tue, 15 Apr 2008 11:39:07 GMT)

Affymetrix Extends Collaborations in Cancer Research Program to North America
SANTA CLARA, Calif.----Affymetrix Inc. today extended its Collaborations in Cancer Research Program to North America, forming an alliance between Affymetrix and 25 leading cancer researchers. (Tue, 15 Apr 2008 12:00:00 GMT)

Calibrant Biosystems Announces Appointment of Dr. Satya Saxena as Vice-President of Research
Calibrant Biosystems today announced the appointment of Dr. Satya Saxena as its Vice-President of Research. Dr. Saxena will lead Calibrant's proteomic technology and product development programs. His primary focus will include expanding and validating the Gemini(TM) platform technology beyond the initial programs in oncology. He will also oversee the continuing drug development efforts involving ... (Tue, 15 Apr 2008 12:00:15 GMT)

Synthetic Biology: Its Promise And The Challenge
Synthetic biology is a new area of biotechnology research that holds a great deal of promise and controversy. Using in-depth understanding of genomes, scientists are now designing and building DNA from scratch. The results are useful organisms that can efficiently produce advanced biofuels and medicines. (Tue, 15 Apr 2008 12:15:15 GMT)

Early Planting Increases Soy Yields
Getting beans in the ground earlier in the spring will benefit come harvest time, according to University of Nebraska research. (Tue, 15 Apr 2008 14:00:56 GMT)

Munich, Germany
April 15, 2008. MWG Biotech , European market leader in genome sequencing and leading expert in next generation sequencing is further expanding its capacities in order to meet the demands of a steadily increasing number of sequencing customers across Europe. (Tue, 15 Apr 2008 16:02:29 GMT)

2 new therapies show promise for cancer patients
San Diego and Phoenix—April 15, 2008—Clinical researchers at Scottsdale Healthcare and TGen today announced the results of two clinical trials that show promise for patients battling cancer. (Tue, 15 Apr 2008 16:59:04 GMT)

St. Jude Gene Study Reveals Basis of Anti-Cancer Drug Resistance in Childhood Leukemia
The findings provide new insights into genomic basis of methotrexate resistance and differences in methotrexate response (Tue, 15 Apr 2008 18:09:00 GMT)

Gene Study Reveals Basis of Anti-Cancer Drug Resistance in Childhood Leukemia
The first analysis of the genetic determinants of resistance to the anti-cancer drug methotrexate in childhood acute lymphoblastic leukemia (ALL) could offer a pathway to predicting such resistance and treatments to overcome it, according to a St. Jude Children's Research Hospital study. (Tue, 15 Apr 2008 18:17:36 GMT)

Health disparities: genetics plays an important role in cancer detection, prognosis among minorities
SAN DIEGO – Research reported at the 2008 Annual Meeting of the American Association for Cancer Research, April 12-16, suggests that poorer outcomes for breast cancer and prostate cancer among minorities may be due to biologic factors. (Tue, 15 Apr 2008 19:09:16 GMT)

Health Disparities: Genetics Plays an Important Role in Cancer Detection, Prognosis Among Minorities
Research reported at the 2008 Annual Meeting of the American Association for Cancer Research, April 12-16, suggests that poorer outcomes for breast cancer and prostate cancer among minorities may be due to biologic factors. In addition, researchers present a new theory on why a recent decline in breast cancer rates was less pronounced among African-American women, and offer data on a relatively ... (Tue, 15 Apr 2008 19:17:56 GMT)

On The Release of His New Book Biotech 2008, Biotech Visionary G. Steven Burrill Will Discuss the Transformation That ...
SAN FRANCISCO----The convergence of genomics, info- and nanotechnologies will radically alter every aspect of the healthcare system from the way companies develop and market drugs to the way individuals pay for and receive medical services, according to G. (Tue, 15 Apr 2008 19:19:00 GMT)

On The Release of His New Book Biotech 2008, Biotech Visionary G. Steven Burrill Will Discuss the Transformation That ...
The convergence of genomics, info- and nanotechnologies will radically alter every aspect of the healthcare system from the way companies develop and market drugs to the way individuals pay for and receive medical services, according to G. Steven Burrill author of Biotech 2008 --Life Sciences: A 20/20 Vision for 2020(1). (Tue, 15 Apr 2008 19:44:22 GMT)

Lexicon Presents Clinical Data for LX6171, a Drug Candidate for Cognitive Disorders
THE WOODLANDS, Texas, April 15, 2008 -- Lexicon Pharmaceuticals, Inc. , a leader in genomics-based drug discovery, presented data today describing the target of LX6171 and initial Phase 1 clinical results at the American Academy of Neurology in Chicago. (Tue, 15 Apr 2008 20:00:00 GMT)

CDC's Genomics Office to Grant Around $3.6M to Translate Genomics to Practice
GenomeWeb Daily News You are not logged in. Existing subscribers login here . New to GenomeWeb Daily News? Register quickly here for your free subscription. (Tue, 15 Apr 2008 20:05:43 GMT)

Clinton Delivers Remarks at Associated Press Annual Meeting
SEN. HILLARY RODHAM CLINTON, D-N.Y.: I know that in this audience there are members of the media from New York, including Margaret Sullivan from the Buffalo News and Arthur Salzberger from the New York Times and others who I don't have on this card, but I am very pleased to be here with all of yo... (Tue, 15 Apr 2008 23:24:52 GMT)

Cancer-drug trials show promise
Two Arizona-based cancer drug trials show early favorable results. (Wed, 16 Apr 2008 03:46:20 GMT)

5-year-old gene-based research institution fights for funding
TGen is competing for a dwindling supply of contributions to pursue its medical advancements. (Wed, 16 Apr 2008 03:46:40 GMT)

Global Molecular Diagnostics Market to Reach $3.67 Billion by 2010, According to New Report by Global Industry ...
World molecular diagnostics market is projected to touch $3.67 billion by 2010. Molecular diagnostics is a rapidly advancing market within the medical diagnostics market, backed by hectic activity in the biomarker research arena, and exploding new applications for these tests. (Wed, 16 Apr 2008 07:01:00 GMT)

St. Jude Gene Study Reveals Basis Of Anti Cancer Drug Resistance In Childhood Leukemia
The first analysis of the genetic determinants of resistance to the anti-cancer drug methotrexate in childhood acute lymphoblastic leukemia (ALL) could offer a pathway to predicting such resistance and treatments to overcome it, according to a St. Jude Children's Research Hospital study. (Wed, 16 Apr 2008 08:14:35 GMT)

Top European Service Provider GATC Biotech Ramps Up Its Fleet of Next-Gen Sequencers with Second Genome Sequencer FLX ...
BRANFORD, Conn.----454 Life Sciences, a centre of excellence of Roche Applied Science, today announced that GATC Biotech, one of Europe's leading sequencing service providers, has acquired a second Genome Sequencer FLX System. (Wed, 16 Apr 2008 11:00:00 GMT)

Top European Service Provider GATC Biotech Ramps Up Its Fleet of Next-Gen Sequencers with Second Genome Sequencer FLX ...
454 Life Sciences, a centre of excellence of Roche Applied Science, today announced that GATC Biotech, one of Europe's leading sequencing service providers, has acquired a second Genome Sequencer FLX System. GATC Biotech's decision to add an additional Genome Sequencer FLX System to its service offering was based both on soaring demand for ultra high-throughput sequencing services as well as the ... (Wed, 16 Apr 2008 11:29:35 GMT)

OpenHelix Joins Coalition For Genetic Fairness
OpenHelix joins forces with other academic and industry luminaries in effort to pass Genetic Information Nondiscrimination Act (GINA). (Wed, 16 Apr 2008 12:00:00 GMT)

Buck Institute And Q Therapeutics Form Stem Cell Collaboration To Combat Parkinson's Disease
The Buck Institute for Age Research and Q Therapeutics, Inc. announced an agreement to collaborate on novel routes to combat Parkinson's disease. The Buck Institute and Q Therapeutics will use their expertise in differentiating stem cells to provide key cell types needed to study Parkinson's disease. (Wed, 16 Apr 2008 12:13:24 GMT)

Illumina Launches The IScan(TM) System
Illumina, Inc. (NASDAQ:ILMN) launched the iScan System, a next-generation scanner that provides researchers conducting genotyping and gene expression studies with significantly greater throughput, enhanced automation, and improved ease of use. (Wed, 16 Apr 2008 12:16:16 GMT)

Gene Network Sciences Names New CSO and Announces New Scientific Advisory Board
Gene Network Sciences, Inc. today announced the creation of the new position of Chief Scientific Officer and a newly constituted Scientific Advisory Board of world class experts from both the biopharmaceutical industry and leading academic organizations. (Wed, 16 Apr 2008 14:17:00 GMT)

Health Disparities: Genetics Plays An Important Role In Cancer Detection, Prognosis Among Minorities
Research reported at the 2008 Annual Meeting of the American Association for Cancer Research, April 12-16, suggests that poorer outcomes for breast cancer and prostate cancer among minorities may be due to biologic factors. (Wed, 16 Apr 2008 15:13:55 GMT)

Measuring medicine: How new technologies could help doctors predict patient outcomes
SAN DIEGO – As potential cancer therapies proliferate, researchers and clinicians are striving to measure their effectiveness and to more accurately predict which patients will receive the most benefit. (Wed, 16 Apr 2008 15:32:28 GMT)

Measuring Medicine: How New Technologies Could Help Doctors Predict Patient Outcomes
As potential cancer therapies proliferate, researchers and clinicians are striving to measure their effectiveness and to more accurately predict which patients will receive the most benefit. At the American Association for Cancer Research 2008 Annual Meeting, April 12-16, 2008, researchers present data on a new role for MRI in brain cancer, how doctors can more effectively measure response to ... (Wed, 16 Apr 2008 16:17:36 GMT)

5-year-old TGen fights for funding
Institution is competing for a dwindling supply of contributions. (Wed, 16 Apr 2008 17:22:25 GMT)

Luminex Corporation First Quarter Earnings Release Scheduled for May 8, 2008
Luminex Corporation (NASDAQ:LMNX) today announced that it expects to report first quarter results on Thursday, May 8, 2008. Results are scheduled for release after the close of trading. (Wed, 16 Apr 2008 17:29:15 GMT)

Nucleosome organization in the Drosophila genome
Comparative genomics of nucleosome positions provides a powerful means for understanding how the organization of chromatin and the transcription machinery co-evolve. (Wed, 16 Apr 2008 17:42:58 GMT)

Molecule Delivery Method Improves Embryonic Stem Cell Differentiation, Georgia Tech-Emory Researchers Say
Editor’s note: This article is part of WRAL Local Tech Wire’s highlighting of research at universities across the Carolinas and Georgia. ATLANTA - Embryonic stem cell therapies have been proposed for regenerative medicine and tissue replacement after injury or disease. (Wed, 16 Apr 2008 18:27:38 GMT)

Bayhill Therapeutics Presents Data From a Phase II Trial of BHT-3009 in Multiple Sclerosis at American Academy of ...
Bayhill Therapeutics, Inc. today announced that the Company's co-founder and Vice President of Research, Hideki Garren, M.D., Ph.D., gave a podium presentation at the American Academy of Neurology 60th Annual Meeting (AAN) in Chicago. Dr. Garren's presentation, "Results from a Phase II Trial of a Myelin Basic Protein Encoding DNA Vaccine for Relapsing Multiple Sclerosis," provides further ... (Wed, 16 Apr 2008 19:44:35 GMT)

Sigma(R) Launches Innovative ChIP Kit Technology For Epigenetic Research
Sigma-Aldrich today announced the launch of its Imprint Chromatin Immunoprecipitation Kit for epigenetic research . (Wed, 16 Apr 2008 20:15:00 GMT)

Danong Chen appointed CEO of Theranostics Health
The Board of Managers of Theranostics Health, LLC, is pleased to announce that Dr. Danong Chen has been elected as the new President and CEO of Theranostics Health. Dr. Chen was previously the President and CEO of Tanox Inc., a publicly held biopharmaceutical company which was acquired by Genentech in 2007. (Wed, 16 Apr 2008 20:30:00 GMT)

The $100 Genome
Forget the $1,000 genome. Some companies are looking far past that goal in the hope of creating a really inexpensive sequencing technology. (Thu, 17 Apr 2008 04:29:29 GMT)

FDA soon may support biomarker tests
The Food and Drug Administration is poised to throw its support behind a powerful new method of predicting the safety of experimental drugs, a step that could help pharmaceutical companies bring treatments to market more quickly - and reduce patients' risk.... (Thu, 17 Apr 2008 04:43:34 GMT)

Basis of anticancer drug resistance in childhood leukaemia found
Washington, Apr 16 : In a new study, researchers at St. Jude Children's Research Hospital have found the basis of resistance provided by anticancer drug, methotrexate in childhood acute lymphoblastic leukemia (ALL). (Thu, 17 Apr 2008 05:17:51 GMT)

New England Peptide Names Antibody Program Manager
New England Peptide, LLC (NEP), has named Kristin Byrne antibody program manager. (Thu, 17 Apr 2008 07:01:00 GMT)

Talks/Authors
The Human Genome Professor Richard Myers, chair of Stanford's Human Genome Center, will present a Powerpoint lecture on "How Human Genomics is Revolutionizing Medicine and Our Understanding of Human Biology." (Thu, 17 Apr 2008 08:26:05 GMT)

Bio lab develops crucial gene software
Through research in the private and academic sectors, scientific efforts have recently succeeded in sequencing the human genome. Only a few people have had their genomes sequenced so far - including Nobel laureate James Watson, who is famous for discovering the helical structure of DNA along with Francis Crick, and geneticist J.Craig Venter, who founded The Institute for Genomic Research. In ... (Thu, 17 Apr 2008 08:28:15 GMT)

Global Molecular Diagnostics Market To Reach 3.67 Billion Dollars By 2010, According To New Report By Global Industry ...
Molecular diagnostics market is being driven by several growth factors, which include the need for automated and easy-to-handle techniques, which combine optimized sample preparation, analysis, and data evaluation, and the growing availability of molecular diagnostic tests for monitoring the therapeutic efficacy of expensive drugs. (Thu, 17 Apr 2008 09:16:29 GMT)

Lexicon's Drug Candidate for Rheumatoid Arthritis, LX2931, Shows Positive Results in Phase 1 Clinical Trial
THE WOODLANDS, Texas, April 17, 2008 -- Lexicon Pharmaceuticals, Inc. , a leader in genomics-based drug discovery, announced today that it has obtained positive results from its initial Phase 1 clinical trial of LX2931, an orally-delivered, small molecule drug candidate for the treatment of rheumatoid arthritis and other autoimmune conditions. (Thu, 17 Apr 2008 10:30:00 GMT)

Cardiac center for campus gets big boost
The state health commissioner has given his crucial backing to the proposed cardiovascular institute on the Buffalo Niagara Medical Campus, generating visions of a world-class health care center downtown staffed by top physicians and offering both treatment and research. (Thu, 17 Apr 2008 10:48:38 GMT)

How New Technologies Could Help Doctors Predict Patient Outcomes
As potential cancer therapies proliferate, researchers and clinicians are striving to measure their effectiveness and to more accurately predict which patients will receive the most benefit. (Thu, 17 Apr 2008 12:13:55 GMT)

The Detection And Prediction Of Circulating Tumor Cells In Breast Cancer Patients
Researchers report a new, noninvasive method for measuring circulating tumor cells in patients with breast cancer, information which can be used to predict the likelihood that cancer will spread. The technique detects circulating tumor cells with 100 percent specificity and 88 percent sensitivity, researchers report. (Thu, 17 Apr 2008 12:15:45 GMT)

Genomics Likely to Replace Traditional Drug Therapies in Treating CHF
The market for congestive heart failure drug treatments was estimated at $18 billion in 2007, and is expected to reach $30 billion by 2017, according to a new report by Kalorama Information, Congestive Heart Failure: Major World Markets, Volume I: Pharmaceutical Management. (Thu, 17 Apr 2008 14:51:00 GMT)

Inbred males' scent gives them away
Female mice can steer clear of inbred males on the basis of their scent alone, according to evidence presented online on April 17th in Current Biology, a Cell Press publication. (Thu, 17 Apr 2008 16:10:04 GMT)

Genomics: Our oil-crunch cure?
Researchers are 'rewriting the software of life,' working to transform artificial DNA into synthetic fuel. This could revolutionize the production of energy. (Thu, 17 Apr 2008 16:49:52 GMT)

Medcotek licenses UB technology
Local company Medcotek Inc. has signed a licensing agreement with UB for use of a new technology that will advance the company’s entry into the lucrative teleradiology market. (Thu, 17 Apr 2008 18:32:35 GMT)

Healthcare Is Undergoing a ‘Metamorphosis,’ FDA Commissioner Says
Cary, N.C. — Healthcare is in the midst of a “metamorphosis” that is changing it from a “caterpillar into a butterfly,” and technology is an essential part of that process, Food and Drug Commissioner Andrew von Eschenbach said Thursday. (Thu, 17 Apr 2008 18:57:39 GMT)

Chemical Genomics Reveals Importance of 'Nonessential' Yeast Genes
GenomeWeb Daily News You are not logged in. Existing subscribers login here . New to GenomeWeb Daily News? Register quickly here for your free subscription. (Thu, 17 Apr 2008 19:51:03 GMT)

Italy eyes bilateral tie-up with India
Italian companies are scouting for markets in India for sale of products like farm implements and machinery and food processing technology. Italy too is planning to boost its exports of a number of food products in which it is competitive. (Thu, 17 Apr 2008 20:58:59 GMT)

North of Boston Business Plan Competition Announces 6 Semi-Finalists 6 Entrepreneurs and New Growth Business Named ...
The North of Boston Business Plan Competition today announced the six semifinalists who will compete for $20,000 in prize money. Hosted by the Enterprise Center at Salem State College, the Merrimack Valley Economic Development Council and the Merrimack Valley Venture Forum, the competition showcases new growth companies in the North of Boston area including the North Shore and Merrimack Valley. ... (Thu, 17 Apr 2008 21:06:00 GMT)

Interaction networks: the new path to drug discovery
Although the pharmaceutical industry has dedicated enormous research efforts over the last 50 years to identify new targets and develop new active ingredients, these efforts have met with limited success. (Fri, 18 Apr 2008 02:34:40 GMT)

Basis Of Anticancer Drug Resistance In Childhood Leukemia Revealed
The first analysis of the genetic determinants of resistance to the anti-cancer drug methotrexate in childhood acute lymphoblastic leukemia could offer a pathway to predicting such resistance and treatments to overcome it, according to a St. Jude Children's Research Hospital study. (Fri, 18 Apr 2008 03:38:49 GMT)

CORRECTING and REPLACING Illumina Launches the iScan(TM) System
SAN DIEGO----Please replace the release dated April 14, 2008 with the following corrected version due to revisions to the second and fifth grafs. (Fri, 18 Apr 2008 09:00:00 GMT)

Blood Test For Aggressive Breast Cancer Sought By Research Collaboration
Mammography and biopsies help find breast cancer, but even biopsies won't tell the doctor if the cancer will spread. Now, a two-year research project hopes to find proteins in blood that could alert doctors to patients harboring not just breast cancer, but the nastiest versions of the disease. (Fri, 18 Apr 2008 09:14:24 GMT)

Study Probes Pure Oxygen's Healing Properties
Pure oxygen therapy is reputed to have many medical benefits, including saving limbs from amputation, and a QUT researcher is setting out to explore its healing properties.PhD researcher James Broadbent, from Queensland University of Technology's School of Life Sciences, is studying pure oxygen, or hyperbaric, therapy's effects on chronic wounds. (Fri, 18 Apr 2008 09:14:34 GMT)

Merial Selects Genostar's IOGMA Metabolic Pathway Builder Bioinformatics Software
Genostar, a developer of bioinformatics software that enables biologists and bioinformaticians to expertly mine and analyze diverse biological data, announced that Merial, a world leader in animal health, has purchased its IOGMA(R) 3.4 Metabolic Pathway Builder software. Genostar's IOGMA(R) 3. (Fri, 18 Apr 2008 09:15:45 GMT)

Bruker Daltonik GmbH Receives ISO 13485 Certification for Development, Manufacturing and Distribution of Mass ...
BARCELONA, Spain----Before the 18th European Congress of Clinical Microbiology and Infectious Disease opening here tomorrow, Bruker Daltonics announces that it has received EN ISO 13485 certification for its German operations. (Fri, 18 Apr 2008 10:00:00 GMT)

Portsmouth area community calendar
Portsmouth (Fri, 18 Apr 2008 10:07:23 GMT)

Bruker Daltonik GmbH Receives ISO 13485 Certification for Development, Manufacturing and Distribution of Mass ...
Before the 18th European Congress of Clinical Microbiology and Infectious Disease (ECCMID) opening here tomorrow, Bruker Daltonics announces that it has received EN ISO 13485 certification for its German operations. This ISO 13485 certification is an important milestone in the development of the Bruker Daltonics in vitro diagnostics (IVD) business, particularly in the fields of clinical ... (Fri, 18 Apr 2008 10:14:25 GMT)

This Practical Guide Describes the Development, Optimization and Validation of Cell-Based Assays
DUBLIN, Ireland----Research and Markets has announced the addition of "Validation of Cell-Based Assays in the GLP Setting: A Practical Guide" to their offering. (Fri, 18 Apr 2008 11:53:00 GMT)

Female mice can identify inbred males by their scent
Scientists at the University of Liverpool have found that female mice avoid mating with inbred males by 'sensing' the diversity of a protein type in their urine. (Fri, 18 Apr 2008 13:32:31 GMT)

Beijing Genomics Institute adds AB SOLiD system to its next generation sequencing technologies
The Beijing Genomics Institute announced today that BGI has added Applied Biosystems SOLiD System to BGI's rapidly expanding next-generation sequencing technologies. (Fri, 18 Apr 2008 13:37:49 GMT)

Mouse Studies Show Tumors Suppress Cells Responsible for Regulating the Immune System
New research has shown that the function of a type of cell that helps modulate immune responses is impaired inside tumors in mice. (Fri, 18 Apr 2008 13:38:30 GMT)

Health Disparities: Genetics Plays An Important Role In Cancer Detection, Prognosis Among Minorities
Poorer outcomes for breast cancer and prostate cancer among minorities may be due to biologic factors, new research suggests. In addition, researchers present a new theory on why a recent decline in breast cancer rates was less pronounced among African-American women, and offer data on a relatively simple means of reducing racial disparities in breast cancer care. ... (Fri, 18 Apr 2008 14:40:02 GMT)

Genomics partnership finds hopeful antibody for MS treatment
An antibody to fight multiple sclerosis might be the first potential treatment coming from a five-year-old state partnership between Mayo Clinic and the University of Minnesota (Fri, 18 Apr 2008 16:29:27 GMT)

Life Sciences Discovery Fund allots $22M in grants
Five Washington health research organizations have received $22 million in funding from the state's Life Sciences Discovery Fund. (Fri, 18 Apr 2008 17:26:20 GMT)

Washington State Funnels $10M into Two Genomics Programs
GenomeWeb Daily News You are not logged in. Existing subscribers login here . New to GenomeWeb Daily News? Register quickly here for your free subscription. (Fri, 18 Apr 2008 19:36:03 GMT)

Takeda Licenses Use of Kinaxo Proteomics Platform
GenomeWeb Daily News You are not logged in. Existing subscribers login here . New to GenomeWeb Daily News? Register quickly here for your free subscription. (Fri, 18 Apr 2008 19:36:23 GMT)

New York State Warns Consumer Genomics Services Firms about Offering Tests
GenomeWeb Daily News You are not logged in. Existing subscribers login here . New to GenomeWeb Daily News? Register quickly here for your free subscription. (Fri, 18 Apr 2008 21:50:43 GMT)

F&M grant will help develop new major
Franklin & Marshall College has been awarded more than $164,000 to help develop a curriculum for a relatively new — and spar (Sat, 19 Apr 2008 05:07:05 GMT)

world travelers
If cat owners know anything about their pets, it's how enigmatic they can be. But scientists have begun to pull back the feline veil, using the latest molecular tools to peek at their origins. (Sat, 19 Apr 2008 07:11:29 GMT)

Portables will relieve the squeeze on UC Merced
MERCED -- Portable buildings aren't stylish, but they will be needed this fall at the University of California at Merced as the three-year-old campus hits capacity. (Sat, 19 Apr 2008 09:25:48 GMT)

How an old man's DNA could save your life
James Watson won a Nobel prize for his role in the discovery of DNA in the 1950s. Now analysis of his genetic code could lead to medical breakthroughs for the rest of us, writes Jonathan Leake (Sat, 19 Apr 2008 20:59:42 GMT)

Childhood in Africa thrilling
Robyn Scott, author of the delightful "Twenty Chickens for a Saddle: The Story of an African Childhood," now lives in London. She spent her first six years of life in lush New Zealand, then her family decided to move to a cow shed in Botswana, partly because of family connections there and because her mother and father loved a challenge. (Sun, 20 Apr 2008 06:27:30 GMT)

'World-class, top-tier research'
The opportunity to quickly turn genomic research into diagnostic tools and treatments to improve the human condition attracted world-renowned scientific leader Richard M. Myers to the HudsonAlpha Institute for Biotechnology. (Sun, 20 Apr 2008 09:19:42 GMT)

HudsonAlpha associate firms
These companies are collocated in the Associates Wing of the HudsonAlpha Institute. Antarus aims to make PCR technology accessible for more students, science educators and individual scientists through the development of robust, affordable, high-quality equipment. (Sun, 20 Apr 2008 09:34:17 GMT)

HudsonAlpha's celebration makes DNA Day special
On Friday, go ahead and wish everyone a "Happy DNA Day" because it has special meaning in Huntsville. (Sun, 20 Apr 2008 09:34:37 GMT)

HudsonAlpha's scientific advisory board world-class
HudsonAlpha Director Richard M. Myers works with and is supported by six uniquely skilled and internationally known investigators and business professionals who provide objective feedback and guidance in scientific matters. (Sun, 20 Apr 2008 09:34:47 GMT)

Genetic variant mimics effect of heart failure medications
A genetic variation, found predominantly in African Americans, protects some people with heart failure, enabling them to live longer than expected. (Sun, 20 Apr 2008 17:03:16 GMT)

Many African-Americans have a gene that prolongs life after heart failure
About 40 percent of African-Americans have a genetic variant that can protect them after heart failure and prolong their lives, according to research conducted at Washington University School of Medicine in St. Louis and collaborating institutions. (Sun, 20 Apr 2008 17:03:17 GMT)

Many African-Americans Have a Gene That Prolongs Life After Heart Failure
About 40 percent of African-Americans have a genetic variant that can protect them after heart failure and prolong their lives, according to research conducted at Washington University School of Medicine in St. Louis and collaborating institutions. The new study offers a reason why beta blockers don't appear to benefit some African-Americans. (Sun, 20 Apr 2008 17:17:36 GMT)

Scientists discover drops of truth in medieval belief in urine
Medieval physicians believed that they could diagnose disease by holding up a flask of the patient’s urine to the light and squinting at it. According to scientists at Imperial College London they could have been on to something. (Sun, 20 Apr 2008 20:29:33 GMT)

Genetic Variant Mimics Effect Of Heart Failure Medications
A genetic variation, found predominantly in African Americans, protects some people with heart failure, enabling them to live longer than expected. Researchers found that the genetic variation acts just like beta-blockers, a class of drugs used to treat chronic heart failure. The researchers say their discovery adds to the accumulating evidence that genetic differences contribute to the way ... (Sun, 20 Apr 2008 20:37:49 GMT)

Many African-Americans Have A Gene That Prolongs Life After Heart Failure
About 40 percent of African-Americans have a genetic variant that can protect them after heart failure and prolong their lives, according to new research. The new study offers a reason why beta blockers don't appear to benefit some African-Americans. (Sun, 20 Apr 2008 20:37:59 GMT)

Ed Pilkington on eating meat from cloned animals
Cloned animals and their offspring have been declared safe to eat; in a matter of months their meat will be on sale in the US. Ed Pilkington reports on a PR timebomb that's about to blow (Sun, 20 Apr 2008 23:12:32 GMT)

Would you eat cloned animal meat?
Meat from cloned animals and their offspring will be on sale in the US in months. Ed Pilkington reports on a PR timebomb that's about to blow (Sun, 20 Apr 2008 23:24:04 GMT)

U.S. Patent Disclosures
Morphotek Inc. , of Exton, Pa., was issued U.S. Patent No. 6,982,169, covering the use of chemical inhibitors to enhance evolution of target host cell genomics by reversibly regulating mismatch repair in vivo. (Mon, 21 Apr 2008 03:08:45 GMT)

Discovery day in Indiana Township to focus on genetics, genomics
More than 120 students from 12 area middle schools will take part in a day of scientific discovery today at Fox Chapel Area's Dorseyville Middle School. (Mon, 21 Apr 2008 04:39:16 GMT)

Bruker Daltonik GmbH Receives ISO 13485 Certification For Development, Manufacturing, And Distribution Of Mass ...
Before the 18 th European Congress of Clinical Microbiology and Infectious Disease (ECCMID) opening here tomorrow, Bruker Daltonics announced that it has received EN ISO 13485 certification for its German operations. (Mon, 21 Apr 2008 04:59:31 GMT)

Some doubt genome's value as health tool
Dr. David Altshuler is a leader in the recent explosion of research linking genes to the risk of common diseases. But if, today, someone came into his airy office at the Broad Institute in Cambridge and dropped a $1,000 read-out of Altshuler's own disease-related genes onto his desk, he says he wouldn't even look at it. (Mon, 21 Apr 2008 05:54:59 GMT)

Back to Beantown: Genstruct Buys Incellico Assets
RESEARCH TRIANGLE PARK — Editor's note: RTP Beat is a regular feature on Thursdays. Bioinformatics software provider Incellico has returned to its roots. Originally founded in Boston in 2000, the company moved to Research Triangle later that year. (Mon, 21 Apr 2008 06:12:58 GMT)

Finnish Biotech Company Sets World Record by Detecting 50 Dangerous Bacteria With Single Test in Quest to Battle Sepsis
The Finnish biotechnology company Mobidiag announced today the Prove-it Bacteria test that sets a world record by being able to detect 50 dangerous bacteria simultaneously - including the widespread "superbug" MRSA. (Mon, 21 Apr 2008 08:00:00 GMT)

Many African Americans Have A Gene That Prolongs Life After Heart Failure
About 40 percent of African Americans have a genetic variant that can protect them after heart failure and prolong their lives, according to research conducted at Washington University School of Medicine in St. Louis and collaborating institutions.The genetic variant has an effect that resembles that of beta blockers, drugs widely prescribed for heart failure. (Mon, 21 Apr 2008 08:17:09 GMT)

KINAXO Biotechnologies Enters Agreement with Takeda
Martinsried, Germany, April 21st, 2008. KINAXO Biotechnologies announced today that it has entered an agreement with Takeda San Diego, Inc., a wholly owned subsidiary of Takeda Pharmaceutical Company Limited Osaka, Japan. (Mon, 21 Apr 2008 09:03:59 GMT)

Can IT fuel the race to the $1,000 human genome?
Ever wonder if you have a genetic disposition to a certain disease, or why a medicine works for your friend, but not for you? (Mon, 21 Apr 2008 09:18:50 GMT)

UH redraws sequence of animals' evolution
The humble sponge, scientists long believed, was at the base of the animal kingdom's evolutionary tree. (Mon, 21 Apr 2008 09:55:38 GMT)

Illumina Announces the HumanHT-12 Gene Expression BeadChip
SAN DIEGO----Illumina, Inc., at its Annual North American User Group Meeting, introduced the HumanHT-12 BeadChip, a twelve sample product designed to accelerate whole genome expression and expression-based Quantitative Trait Loci studies. (Mon, 21 Apr 2008 10:00:00 GMT)

OTI rising from the ashes
Just when everyone thought it was dead, the Ottawa Talent Initiative (OTI) is staging a comeback. (Mon, 21 Apr 2008 10:04:18 GMT)

Potential MS Therapy Advanced By Minnesota Partnership
A production laboratory founded by the Minnesota Partnership has transferred its first potential therapy - a medication for multiple sclerosis - to a processing plant in Minnesota. This step will complete purification of material to fully enable translation from preclinical to clinical development. (Mon, 21 Apr 2008 10:13:24 GMT)

Technology To Detect Liver Disease Via Blood Test To Be Developed
No simple blood test exists to determine which of the millions of people infected with hepatitis C virus will develop cirrhosis of the liver or cancer. Now, researchers are developing new technology to find blood proteins that herald the earliest signs of chronic liver disease. (Mon, 21 Apr 2008 10:13:54 GMT)

Awards To Launch Health Research Granted By Life Sciences Fund
The Life Sciences Discovery Fund (LSDF) has awarded $22 million in grant funding to 5 Washington State-based life sciences organizations and their partners. The newly-funded health research initiatives focus on the areas of medical genetics, autoimmunity, cancer clinical trials, proteomics-based diagnostics and early learning and brain development (See Backgrounder Information). (Mon, 21 Apr 2008 10:14:14 GMT)

AB SOLiD System Added To Beijing Genomics Institute's Next Generation Sequencing Technologies
The Beijing Genomics Institute has announced that BGI has added Applied Biosystems SOLiD System to BGI's rapidly expanding next-generation sequencing technologies.Two AB SOLiD Systems have been installed and were thoroughly tested by the BGI researchers. The AB SOLiD System generated high-throughput high quality mate-pair data with read lengths up to 25 bp. (Mon, 21 Apr 2008 10:15:51 GMT)

Illumina Announces the HumanHT-12 Gene Expression BeadChip
Illumina, Inc., (NASDAQ:ILMN) at its Annual North American User Group Meeting, introduced the HumanHT-12 BeadChip, a twelve sample product designed to accelerate whole genome expression and expression-based Quantitative Trait Loci (eQTL) studies. The HumanHT-12 BeadChip includes over 48,000 probes per sample and is priced at $75, supporting a total cost of $100 per sample including labeling ... (Mon, 21 Apr 2008 10:29:45 GMT)

Mouse Studies Show Tumors Suppress Cells Responsible For Regulating The Immune System
New research has shown that the function of a type of cell that helps modulate immune responses is impaired inside tumors in mice. Researchers also identified several factors that may contribute to an accumulation of these cells, called T regulatory cells (Tregs), within and around the tumor, which may be how they respond to their loss of functionality. (Mon, 21 Apr 2008 12:14:24 GMT)

Power3 Medical Products Issues Letter to Shareholders
HOUSTON----Power3 Medical Products, Inc. , a leading proteomics company specializing in the development and commercialization of diagnostic tests for the early detection of breast cancer and neurodegenerative diseases, is pleased to issue a letter to its shareholders, providing an overview of recent developments, from Steve Rash, Chief Executive Officer of Power3. (Mon, 21 Apr 2008 12:45:00 GMT)

ots: Strong alliance to fight fungal infections
------------------------------ ots.CorporateNews transmitted by euro adhoc. The issuer is responsible for the content of this announcement. (Mon, 21 Apr 2008 12:47:09 GMT)

Strong alliance to fight fungal infections
» Intercell and its partner institutions are awarded an EU grant for targeting research and novel treatments of fungal infections » Intercell further strengthens its fungal franchise by supporting the new Christian Doppler Laboratory “PathoFUN” focusing on the research of fungal pathogens ... (Mon, 21 Apr 2008 13:07:57 GMT)

Power3 Medical Products Issues Letter to Shareholders
Power3 Medical Products, Inc. (OTCBB: PWRM, https://www.power3medical.com) a leading proteomics company specializing in the development and commercialization of diagnostic tests for the early detection of breast cancer and neurodegenerative diseases, is pleased to issue a letter to its shareholders, providing an overview of recent developments, from Steve Rash, Chief Executive Officer of ... (Mon, 21 Apr 2008 13:14:25 GMT)

Digilab Genomic Solutions(R) Inks Distribution and Supply and License and Supply Agreements with CyBio AG
Digilab Genomic Solutions(R) (DGS) today announced it has entered into Distribution and Supply and License and Supply Agreements with CyBio AG. (Mon, 21 Apr 2008 13:46:21 GMT)

Strong alliance to fight fungal infections
DJ Strong alliance to fight fungal infections =- ots.CorporateNews transmitted by euro adhoc. The issuer is responsible for the content of this announcement. ... (Mon, 21 Apr 2008 13:50:37 GMT)

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