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Bioinformatics News 07/2007 (Page 3)

Gene mutation affecting cancer treatment found (PharmaBiz)
Researchers from Eli Lilly & Company and the Phoenix-based Translational Genomics Research Institute (TGen) announced finding a novel recurring mutation of the gene AKT1 in breast, colorectal and ovarian cancers.

SuperGen Reports Dosing Of First Patient In Phase I Trial Of Novel Tyrosine Kinase Inhibitor (Medical News Today)
SuperGen, Inc. (Nasdaq: SUPG) today announced that collaborators at The Translational Genomics Research Institute (TGen) and TGen Clinical Research Services (TCRS) at Scottsdale Healthcare in Scottsdale, Arizona, have dosed the first patient in a Phase I clinical trial of MP470, a novel, oral, multi-targeted tyrosine kinase inhibitor (TKI). [click link for full article]

Yale Leaders In 6 Million Dollars International Effort To Fight Hypertension (Medical News Today)
Leading researchers in Switzerland, France, Mexico, and at Yale School of Medicine, are pooling efforts under a five-year, 6 million dollars grant from the Leducq Foundation to pinpoint the kidney's role in high blood pressure. [click link for full article]

Expanding The Genetic Code In Living Mammalian Cells (Medical News Today)
Researchers at the Salk Institute for Biological Studies have developed a novel strategy to expand the natural repertoire of 20 amino acids in mammalian cells, including neurons, and successfully inserted tailor-made amino acids into proteins in these cells. [click link for full article]

Waters Redefines Molecular Characterization Science at ASMS 2007 (ThomasNet)
New Innovations Push Limits of Biological and Chemical Molecular Science for Improved Discovery and Qualification MILFORD, Mass., May 31 / - Waters Corporation will highlight new mass spectrometry (MS), proteomics and software innovations focused on characterizing and visualizing molecules at the 55th annual American Society for Mass Spectrometry, June 3-7, in Indianapolis, Ind. Complete ...

Newly discovered gene mutation gives insight into cancers (The Indianapolis Star)
INDIANAPOLIS -- Researchers from Eli Lilly and Co. helped discover a gene mutation that provides insights in fighting breast, colorectal and ovarian cancers, the company said Wednesday. The Indianapolis drug maker and Phoenix-based Translational Genomics Research Institute made the finding.

Visual Sciences Research Center Receives 3.2M Dollars Award (Medical News Today)
The Visual Sciences Research Center (VSRC) of Case Western Reserve University School of Medicine and the Research Institute of University Hospitals Case Medical Center has been awarded a 3.2 million dollars renewal over 5 years of their Core Grant from the National Eye Institute (NEI), one of the government's National Institutes of Health. [click link for full article]

Around Pasadena (Pasadena Star-News)
ARCADIA - Altadena-based Art Aids Art will present a screening of the new documentary "Bigger than Barbie," featuring the 450 female artists of Monkeybiz Bead Project.

Two Bioinformatics-Related Software Programs Featured In This Month's Cold Spring Harbor Protocols (Medical News Today)
Large-scale undertakings such as the Human Genome Project have produced massive amounts of data. To make sense of it all, powerful mathematical and statistical algorithms were developed, resulting in the interdisciplinary field called 'bioinformatics. [click link for full article]

Around Pasadena (Pasadena Star-News)
ARCADIA - Altadena-based Art Aids Art will present a screening of the new documentary "Bigger than Barbie," featuring the 450 female artists of Monkeybiz Bead Project.

Around Pasadena (Pasadena Star-News)
ARCADIA - Altadena-based Art Aids Art will present a screening of the new documentary "Bigger than Barbie," featuring the 450 female artists of Monkeybiz Bead Project.

Genetically, sea anemone has human complexity (Honolulu Star-Bulletin)
Scientists studying a starlet sea anemone thought that since it's a simple animal it would have a simple genome. The tiny creature fooled them.

The second wave (Express India)
You could call IT an inspiration. As the Indian tech industry reaffirmed its $50 billion promise last week, the fledgling biotech sector seems to be getting ready to raise the bar too.

Mapping Complex Diseases (Technology Review)
A computer model of epidemiological data from 1.5 million people illuminates the genetic origins of many common diseases.

Jefferson oncologists show breast cancers to be more aggressive in African-American women (EurekAlert!)
(PHILADELPHIA) A study of more than 2,200 women at the Kimmel Cancer Center at Jefferson in Philadelphia shows that African American women have more advanced breast cancer at the time of diagnosis than Caucasian women.

Size and positioning of floral anthers facilitates pollen collection by bees (EurekAlert!)
Unlike moths and butterflies that are often brilliantly colored to warn potential predators that they carry toxins, flowers and the fruits they produce have brilliant colors and unusual shapes because they want to attract the attention of pollinators and frugivores who will disperse their pollen and seed, thus guaranteeing the next generation.

TGen discovers cancer treatment breakthrough (BizJournals)
Researchers from the Translational Genomics Research Institute and Eli Lilly & Co. have discovered what bioscience experts say may be a major breakthrough in cancer treatment.

Danish Biotech Company Egalet Strengthens Management by Appointing Internationally Experienced CFO (PR Newswire via Yahoo! Finance)
Danish specialty pharmaceutical company Egalet has appointed Mr Bertrand Damour as its Chief Financial Officer and Executive Vice President. Mr Damour has extensive experience in the international financial markets and biotechnology industry and will reinforce Egalet's position in the global pharmaceutical and biotechnology sector.

Researchers Identify Genetic Mutation That May Alter Patients' Response To Cancer Therapeutics (Medical News Today)
Researchers from Eli Lilly & Company and the Phoenix-based Translational Genomics Research Institute (TGen) today announced finding a novel recurring mutation of the gene AKT1 in breast, colorectal and ovarian cancers. The altered form of AKT1 appears to cause tumor cell proliferation and may play a role in making cells resistant to certain types of therapies. [click link for full article]

Now every dog can have its DNA . . . tested (Philly.com)
In the genes: Vernita Gundy's Chihuahua Coco is ferocious enough to scare Robin Tower's Old English sheepdog Bleu as they meet near Rittenhouse Square.

Research & IdeasAnemone Genome More Similar To Humans’ Than Expected (The Daily Californian)
Sea anemones and human beings have much more in common biologically than outward appearances would suggest, according to research from UC Berkeley scientists published Friday in Science Magazine.

09 July 2007 (PharmiWeb)
Danish specialty pharmaceutical company Egalet has appointed Mr Bertrand Damour as its Chief Financial Officer and Executive Vice President.

DNAPrint(R) Genomics Announces Acceptance of Studies for Publication (SYS-CON Media)
DNAPrint® Genomics (OTCBB: DNAG), which holds two patents and has seven patent applications pending related to genetic markers, today announced that two studies performed by Company Founder and Chief Science Officer Tony Frudakis, Ph.D., will be published in peer reviewed scientific journals in the coming months.

Affymetrix Launches European Cytogenetic Research Initiative (Business Wire via Yahoo! Finance)
SANTA CLARA, Calif.----Affymetrix Inc. today announced the launch of the European Cytogenetic Research Initiative, a collaboration between Affymetrix, the University of Nijmegen in the Netherlands, the University of Tuebingen in Germany and the NHS Regional Genetics Laboratory in Birmingham, U.K.

Merrimack Pharmaceuticals Reduces Drug Discovery Time with SimBiology (Business Wire via Yahoo! Finance)
NATICK, Mass.----The MathWorks today announced that Merrimack Pharmaceuticals is using SimBiology® to streamline the research and development of therapeutics to treat autoimmune disease and cancer.

Merrimack Pharmaceuticals Reduces Drug Discovery Time with SimBiology: Pharmaceutical Research Company Uses MathWorks ... (PRWeb)
The MathWorks(tm) today announced that Merrimack Pharmaceuticals is using SimBiology(R) to streamline the research and development of therapeutics to treat autoimmune disease and cancer. (PRWeb Jul 9, 2007) Post Comment:Trackback URL: http://www.prweb.com/pingpr.ph

Affymetrix Launches European Cytogenetic Research Initiative (FinanzNachrichten)
Affymetrix Inc. ( Nachrichten ) (Nasdaq:AFFX) today announced the launch of the European Cytogenetic Research Initiative, a collaboration between Affymetrix, the University of Nijmegen in the Netherlands, the University of Tuebingen in Germany and the NHS Regional Genetics Laboratory in Birmingham, U.K. The collaborators are using Affymetrix microarray technology to identify the specific ...

Neah Power Announces Fuel Cell Development Executive Promotion (Business Wire via Yahoo! Finance)
BOTHELL, Wash.----Neah Power Systems, Inc. , a leading developer of fuel cells for military applications, notebook computers and portable electronic devices, announced today that David Wine, former Director of Cell and Stack Development, has been promoted to Vice President of Development.

Lab-on-Chip and Microfluidics Technologies' Capability to Reduce Costs and Time-to-Market Drive Uptake in Drug ... (PR Newswire via Yahoo! Finance)
The adoption of microfluidics not only provides pharmaceuticals companies multiple benefits such as improved data quality and economized reagent consumption, but also significantly reduces the time and cost of producing large amounts of biological material, which helps drug developing companies to reduce initial expenses of drug development.

Naren Ramakrishnan Recognized by Computerworld (Newswise)
Naren Ramakrishnan, associate professor of computer science at Virginia Tech, has been named as one of Computerworld's "40 innovative IT people to watch, under the age of 40." The award recognizes contributions to the areas of data mining, personalization, and problem solving environments. In particular, he is being recognized for the data mining paradigm called "storytelling."

Decoding The Evolution Of Flowers: From Genomes To Petals (Science Daily)
Unlike moths and butterflies that are often brilliantly colored to warn potential predators that they carry toxins, flowers and the fruits they produce have brilliant colors and unusual shapes because they want to attract the attention of pollinators and frugivores who will disperse their pollen and seed, thus guaranteeing the next generation. It turns out that the sizes and positioning of the ...

TRADE NEWS: Agilent Technologies Licenses Kreatech Technology, Enabling First CGH Microarrays Optimized for FFPE Samples (Business Wire via Yahoo! Finance)
SANTA CLARA, Calif., & AMSTERDAM, The Netherlands----Agilent Technologies Inc. and Kreatech Biotechnology B.V. announced today that Agilent has licensed novel labeling technology from Kreatech, which will optimize Agilent's array-based comparative genomic hybridization platform for DNA from formalin-fixed paraffin-embedded tissue samples.

Affymetrix technology to be used in mental retardation research (bizjournals.com via Yahoo! Finance)
Affymetrix Inc. is collaborating with universities and laboratories to launch the European Cytogenetic Research Initiative to investigate causes of mental retardation, the company said Monday.

Venter Takes Step Toward Synthetic Cells (Forbes)
The experiment is part of an explosion in the new field of synthetic biology.

First Winner of Minority Scholar Award to Begin Clinical Research (PR Newswire via Yahoo! News)
Christopher Flowers, MD, the first winner of the ASH-AMFDP, an award designed to help increase the number of underrepresented minority scholars in the field of hematology, begins his research award this month (in July). The award, the result of a partnership between the American Society of Hematology (ASH) and the Harold Amos Medical Faculty Development Program (AMFDP) of the Robert Wood Johnson ...

Roche in $272m NimbleGen buy (Financial Times)
Roche continued its strategy of selective small acquisitions on Tuesday with the $272.5m purchase of NimbleGen Systems, a US genomics research company.

'Virtual' mouse brains now available online (EurekAlert!)
DURHAM, N.C. -- A multi-institutional consortium including Duke University has created startlingly crisp 3-D microscopic views of tiny mouse brains -- unveiled layer by layer -- by extending the capabilities of conventional magnetic resonance imaging.

Scientific Computing, Leopard and WWDC Slides (The Mac Observer)
A slide presentation on what's new in Leopard in the context of scientific computing has been linked at MacResearch.org by Alexander Griekspoor, European Bioinformatics Institute, Hinxton

Global community listens to TAU genetic researcher at EU Conference on Hearing Loss (EurekAlert!)
Paris -- Prof. Karen Avraham, chair of the department of human molecular genetics and biochemistry at Tel Aviv University’s Sackler School of Medicine, represented EuroHear, a consortium of 25 European, Israeli and U.K.-based research teams, at the European Union conference “Hearing and Seeing: European Research to Fight Deafness and Blindness,” held at Paris’s College de France on July 2-3, 2007.

'Virtual' Mouse Brains WIth Extraordinary Detail Available (Science Daily)
A multi-institutional consortium including Duke University has created startlingly crisp 3-D microscopic views of tiny mouse brains -- unveiled layer by layer -- by extending the capabilities of conventional magnetic resonance imaging. Using computer-guided statistical methods, the data can be segmented into more than 30 anatomical structures with quantitative volume measurements. These ...

QIAGEN Completes Acquisition of eGene (PrimeNewswire via Yahoo! Finance)
VENLO, The Netherlands, July 9, 2007 -- QIAGEN N.V. ; , the world's leading provider of sample and assay technologies for research in life sciences, applied testing and molecular diagnostics, today announced that its subsidiary QIAGEN North American Holdings, Inc. has completed its acquisition of eGene, Inc. in a transaction at $0.65 in cash and 0.0416 common shares of QIAGEN stock per share of ...

Breast Cancers Is More Aggressive In African-American Women, Study Shows (Science Daily)
A study of more than 2,200 women shows that African-Americans have more advanced breast cancer at the time of diagnosis than Caucasians. African-American women tend to have breast cancer tumor types that are more aggressive and have poorer prognoses. The findings are in line with other recent studies, and provide more evidence of the continuing need for early breast cancer screening for ...

New Angle On Our Multi-Celled Ancestors Provided By Sea Anemone Genome (Medical News Today)
The first analysis of the genome of the sea anemone shows it to be nearly as complex as the human genome, providing major insights into the common ancestor of not only humans and sea anemones, but of nearly all multi-celled animals. [click link for full article]

SUNY RESEARCHERS FUNDED TO FIGHT LEAD POISON (Palladium Times)
The National Institutes of Health has awarded a grant of more than $200,000 to researchers at SUNY Oswego to continue their investigation into the effects of low levels of lead on cardiovascular functioning in children and to look into exactly how lead produces those effects.

NIH-Funded Study Examines Lead's Effects On Children's Cardiovascular Health (Oswego Daily News)
OSWEGO, NY - National Institutes of Health has awarded a grant of more than $200,000 to researchers at SUNY Oswego to continue their investigation into the effects of low levels of lead on cardiovascular functioning in children and to look into exactly how lead produces those effects.

UW professor wins major genetics prize (Seattle Times)
A university of Washington professor who helped convince the scientific community that it would be worthwhile ...d feasible —...

Article Tools (Sunday Times)
MEXICO CITY - Scientists have mapped the corn genome, which should lead to bumper crops of Mexico’s staple vegetable, Secretary of Agriculture Alberto Cardenas announced on Monday.

Neah Power promotes David Wine to vice president of development (Fuel Cell Today)
Neah Power Systems has announced the appointment of David Wine as vice president of development. Mr Wine had previously worked for the developer of fuel cells for military applications, notebook computers and personal electronic devices as director of cell and stack development.

Mexico's National Institute of Genomic Medicine (INMEGEN) Unveils New Illumina Genotyping and Gene Expression Analysis ... (Business Wire via Yahoo! Finance)
SAN DIEGO----Illumina, Inc. today announced the opening of a Genotyping and Gene Expression Analysis Unit at the National Institute of Genomic Medicine in Mexico City. The new unit is part of a 40,000 square foot facility being constructed by INMEGEN and will house a fully-automated Illumina BeadStation.

XDx Selects Ingenuity Systems IPA 5.0 for Pathways Solution (PR Newswire via Yahoo! Finance)
Ingenuity Systems, the leading provider of solutions to explore, analyze, and interpret scientific literature and data, today announced that XDx, a leading molecular diagnostics company, has licensed Ingenuity's flagship solution IPA 5.0.


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