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Bioinformatics News 07/2007

Changing one germ to another? (Daily Bulletin)
WASHINGTON - Talk about identity theft: Scientists changed one species of bacteria into another by performing a complete gene swap. It's a step in the quest to one day create artificial organisms, part of a bigger project to custom-design microbes that could produce cleaner fuels.

Training America's mathematicians (Contra Costa Times)
If there are 30 people in a room, the odds are 2 to 1 that two of them will have the same birthday. It's an amusing parlor trick, but there's some serious math behind it.

Thalassemia patients given a better chance (The Nation)
The development is still in its early stages but it could be complete in three years. Stem-cell therapy involves obtaining processed tissue from animal embryos, foetuses, or organs that are injected into a patient.

Translating form into function (EurekAlert!)
In the last 40 years, scientists have perfected ways to determine the knot-like structure of enzymes, but they’ve been stumped trying to translate the structure into an understanding of function – what the enzyme actually does in the body.

deCODE Discovers a Variation in the Sequence of the Genome Conferring Risk of Atrial Fibrillation (PR Newswire via Yahoo! Finance)
A paper published today in the journal Nature describes the discovery by scientists at deCODE genetics , in collaboration with academic colleagues in Iceland, the United States, Sweden and China, of two common single-letter variations in the genome conferring risk of atrial fibrillation .

Structure-based activity prediction for an enzyme of unknown function (Nature)
With many genomes sequenced, a pressing challenge in biology is predicting the function of the proteins that the genes encode. When proteins are unrelated to others of known activity, bioinformatics inference for function becomes problematic.

Doing nature one better: Expanding the genetic code in living mammalian cells (EurekAlert!)
La Jolla, CA — Researchers at the Salk Institute for Biological Studies have developed a novel strategy to expand the natural repertoire of 20 amino acids in mammalian cells, including neurons, and successfully inserted tailor-made amino acids into proteins in these cells.

New method for reading DNA sheds light on basis of cell identity (EurekAlert!)
As a fertilized egg develops into a full grown adult, mammalian cells make many crucial decisions — closing doors of opportunity as they adopt careers as liver cells, skin cells, or neurons.

Scientia Advisors Will be a Panelist at the Mass Medic - On the Subject of Point of Care Diagnostics & Tech (PR.com)
Scientia Advisors Management Consultant and Managing Partner, Harry Glorikian, will be a panelist at the Mass Medic - on the subject of Point of Care Diagnostics & Technology – September 12, 2007 [PR.com - June 30, 2007]

Scientia Advisors Will Speak at the Enabling Point of Care Diagnostics Meeting Held by CHI (PR.com)
Harry Glorikian, will be a speaker at Enabling Point of Care Diagnostics meeting held by CHI, Washington, DC - on Point of Care Diagnostics & Technology: The State of the Industry [PR.com - June 30, 2007]

deCODE Discovers a Variation in the Sequence of the Genome Conferring Risk of Atrial Fibrillation (FinanzNachrichten)
REYKJAVIK, Iceland, July 1 /PRNewswire-FirstCall/ -- A paper published today in the journal Nature describes the discovery by scientists at deCODE genetics ( Nachrichten ), in collaboration with academic colleagues in Iceland, the United States, Sweden and China, of two common single-letter variations in the genome (SNPs) conferring risk of atrial fibrillation (AF). AF is the most common cardiac ...

New Method for Reading DNA Sheds Light on Basis of Cell Identity (Newswise)
By using a new kind of genomic technology, a new study unveils a special code -- not within DNA, but within the so-called "chromatin" proteins surrounding it -- that could unlock the mysterious developmental choices made by mammalian cells, allowing them to assume roles as diverse as liver cells and neurons.

Doing Nature One Better: Expanding the Genetic Code in Living Mammalian Cells (Newswise)
Researchers have developed a novel strategy to expand the natural repertoire of 20 amino acids in mammalian cells, including neurons, and successfully inserted tailor-made amino acids into proteins in these cells. In a powerful demonstration of the method's versatility, they then used unnatural amino acids to determine the operating mechanism of the "molecular gates" that regulate the movement of ...

Doing nature one better: Expanding the genetic code in living mammalian cells (PhysOrg)
Researchers at the Salk Institute for Biological Studies have developed a novel strategy to expand the natural repertoire of 20 amino acids in mammalian cells, including neurons, and successfully inserted tailor-made amino acids into proteins in these cells. In a powerful demonstration of the method`s versatility, they then used unnatural amino acids to determine the operating mechanism of the ...

Translating form into function (PhysOrg)
In the last 40 years, scientists have perfected ways to determine the knot-like structure of enzymes, but they`ve been stumped trying to translate the structure into an understanding of function - what the enzyme actually does in the body. This puzzle has hindered drug discovery, since many of the most successful drugs work by blocking enzyme action. Now, in an expedited article in Nature, ...

Goal for DNA research? World peace (USA Today)
Utah's richest man can't sit still for a TV program or a movie because he gets lost in the most simple plot. Yet, ideas gush from James LeVoy Sorenson like music from a savant.

Molecular & Cellular Proteomics News (Medical News Today)
Proteins' role in coronary heart disease Scientists provided the first large-scale identification of the proteins involved in coronary heart disease. The information will help to better understand the progression of the disease, improve diagnosis, and detect early pathological signs more efficiently. [click link for full article]

Current Issue: (California Aggie)
As of June 26, UC Davis researchers are partners in a new $125 million federal bioenergy research center, according to the U.S. Department of Energy.

Hughes institute funds 'real-life' science projects in N.E. (BizJournals)
Scientists at the Marine Biological Laboratory in Woods Hole won a $725,225 grant to develop a nationwide program to educate high school students and teachers about biotechnology.

Chemical giant offshoots establish local start-ups (The Philadelphia Inquirer)
Barry L. Marrs was director of life-sciences research at DuPont in 1994. Two years ago, he founded Athena Biotechnologies, which "scares" plants into secreting chemicals for potential new drugs and agriculture products. The company leases space from DuPont - which is also a customer.

Prof Samir K Brahmachari, Dr MRS Rao jointly win bio-medical research award (ANI via Yahoo! India News)
New Delhi, July 2 (ANI): Prof. Samir K Brahmachari and Dr. MRS Rao will be jointly awarded the Dr B R Ambedkar Centenary Award for the year 2005 for their outstanding contribution in the field of bio-medical research. The award carries a cash prize of rupees one lakh. Besides, the Indian Council of Medical Research (ICMR) has selected 31 biomedical scientists from across the country to be ...

Acacia Technologies Enters into License Agreement with . (Stock World)
NEWPORT BEACH, Calif.--(BUSINESS WIRE)--Acacia Research Corporation (Nasdaq:ACTG)(Nasdaq:CBMX) announced today that its Disc Link Corporation subsidiary, which is part of its Acacia Technologies group, a leader in technology licensing, has entered into a license agreement with Kofax Image Products, Inc. covering patents relating to portable storage devices with links.

Illumina Commences Shipment of the Human1M BeadChip (Stock World)
The Industrys First Single-Chip DNA Analysis Solution to Contain More Than One Million SNPs SAN DIEGO--(BUSINESS WIRE)--Illumina, Inc. (NASDAQ:ILMN) announced today that it began shipment of the new Human1M DNA Analysis BeadChip last week, a solution that contains more than one million single-nucleotide polymorphisms (SNPs) on a single chip.

Acacia Technologies Licenses Credit Card Fraud Protectio. (Stock World)
NEWPORT BEACH, Calif.--(BUSINESS WIRE)--Acacia Research Corporation (Nasdaq:ACTG)(Nasdaq:CBMX) announced today that Financial Systems Innovation LLC, a wholly owned subsidiary of the Acacia Technologies group, a leader in technology licensing, has entered into a non-exclusive license covering a patent that applies to credit card fraud protection technology with Sears Holdings Management ...

Acacia Technologies Licenses Pop-up Advertisement Tech. (Stock World)
NEWPORT BEACH, Calif.--(BUSINESS WIRE)--Acacia Research Corporation (Nasdaq:ACTG)(Nasdaq:CBMX) announced today that InternetAd Systems, LLC, a wholly owned subsidiary that is part of the Acacia Technologies group, a leader in technology licensing, has entered into a release and license Agreement with JBS Sports, Inc. dba Rivals.com, covering a portfolio of patents that apply to Pop-Up Advertising.

Acacia Technologies Enters into License Agreement with . (Stock World)
NEWPORT BEACH, Calif.--(BUSINESS WIRE)--Acacia Research Corporation (Nasdaq:ACTG)(Nasdaq:CBMX) announced today that its Disc Link Corporation subsidiary, which is part of its Acacia Technologies group, a leader in technology licensing, has entered into a license agreement with Nuance Communications, Inc. covering patents relating to portable storage devices with links.

Acacia Technologies Enters into License Agreement with . (Stock World)
NEWPORT BEACH, Calif.--(BUSINESS WIRE)--Acacia Research Corporation (Nasdaq:ACTG)(Nasdaq:CBMX) announced today that its Disc Link Corporation subsidiary, which is part of its Acacia Technologies group, a leader in technology licensing, has entered into a license agreement with Palo Alto Software, Inc. covering patents relating to portable storage devices with links.

Acacia Technologies Licenses Credit Card Fraud Protection Technology to Sears (Broadcast Newsroom)
NEWPORT BEACH, Calif.,

Tycoon succeeds in 'genome transplant' (New Scientist)
US genomics pioneer Craig Venter has turned one species of bacterium into another – another step towards his goal of creating a synthetic life-form

Invitrogen to Host Annual Investor Day Thursday, August 16, 2007 (Business Wire via Yahoo! Finance)
CARLSBAD, Calif.----Invitrogen Corporation announced that it will be hosting its 2007 Annual Investor Day conference on Thursday, August 16, 2007, at its Molecular Probes facility in Eugene, Oregon.

Goal for DNA research? World peace (USATODAY.com via Yahoo! News)
SALT LAKE CITY - Utah's richest man can't sit still for a TV program or a movie because he gets lost in the most simple plot. Yet, ideas gush from James LeVoy Sorenson like music from a savant.

Genetic Association Information Network Selects Affymetrix SNP Array 6.0 for Latest Series of Studies (FinanzNachrichten)
Affymetrix Inc. ( Nachrichten ) (Nasdaq:AFFX) today announced that the Genetic Association Information Network (GAIN) will use the recently launched Genome-Wide Human SNP Array 6.0 for a series of studies designed to identify the genetic causes of common, complex diseases such as schizophrenia and bipolar disorder.

'Junk' DNA makes compulsive reading (New Scientist)
A mammoth investigation of human DNA finds it generates far more RNA than thought - so what is the excess for?

Angry reception greets patent for synthetic life (New Scientist)
Controversial tycoon Craig Venter raises a storm of protest by applying for a patent on a minimal genome which could be used to create life

Scientists Discover Role Of Enzyme In DNA Repair (Medical News Today)
Scientists from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Cancer Institute (NCI), and Integrative Bioinformatics Inc. have made an important discovery about the role of an enzyme called ataxia telangiectasia mutated protein (ATM) in the body's ability to repair damaged DNA. NIAMS and NCI are part of the National Institutes of Health (NIH). [click ...

SeedQuest - Central information website for the global seed industry (SeedQuest)
The European Technology Platform (ETP) ‘ Plants for the Future ’ launched its Strategic Research Agenda (SRA) on 25 June 2007 at the European Parliament. This is yet another milestone on the road to putting plant sciences back on the agenda in Europe and its Member States.

Cantor Fitzgerald initiates coverage of Rosetta Genomics (Globes Online)
The investment house gives the micro-RNA drug company a "buy" rating and price target of $15.

Thalassemia patients given a better chance (The Nation)
The development is still in its early stages but it could be complete in three years. Stem-cell therapy involves obtaining processed tissue from animal embryos, foetuses, or organs that are injected into a patient.

Dog owners eager to dig into Fido's pedigree (The Charlotte Observer)
Every morning, white postal bins stuffed with envelopes show up at MMI Genomics in Davis, Calif., posing the question asked by just about anyone who has ever marveled at a magnificent mutt. What kind of dog is that, anyway? The answer lies on tiny bristles full of dog slobber, and hopefully skin cells, collected by owners who have gently brushed the insides of their dogs' cheeks.

Expression Analysis Hires Senior Director of Quality Systems (Business Wire via Yahoo! Finance)
DURHAM, N.C.----Expression Analysis, Inc., a leading global provider of genomic services for clinical trials, including Affymetrix GeneChip® , Illumina BeadArray®, Luminex xMAP® and Applied Biosystems' TaqMan® technologies, has hired C.

Bioinformatics-related methods are featured in Cold Spring Harbor Protocols (EurekAlert!)
Cold Spring Harbor, NY – Large-scale undertakings such as the Human Genome Project have produced massive amounts of data. To make sense of it all, powerful mathematical and statistical algorithms were developed, resulting in the interdisciplinary field called “bioinformatics.”

Buzz builds for Bioscience High (The Arizona Republic)
At the new Bioscience High in Phoenix, which opens in August, students will tap data into laptop computers and splice DNA in labs that would rival what you'd see at colleges and research facilities.

How to enter biotech studies (The Arizona Republic)
Tips for getting ready for biotechnology.

Bioscience High is open to all kids (The Arizona Republic)
Starting June 21, incoming freshman, regardless of where they live, can apply to attend the new Bioscience High School in Phoenix. Until now, enrollment was limited to students who live within the Phoenix Union High School district students.

GNI Forms Alliance with BIOBASE (Business Wire via Yahoo!7 Finance)
GNI Ltd, a leading biopharmaceutical company in Asia, today announced that it has formed a technology and business alliance with BIOBASE GmbH, a leading content provider of biological databases, knowledge tools and software for the life science industry. GNI and BIOBASE will further develop and market Cell Illustrator 3.0, a biological illustration and biopathway modeling software tool.

Scientists claim cure for food allergy (The Times of India)
NEW DELHI: Those suffering from food allergy might soon be able to safely dig into the sumptuous tiger prawn that earlier made their face bloat up and their throat itch or even cherish a pack of crunchy honey dipped peanut by the lake that till now caused skin rashes and stomach cramps.

At 16, triple-degree Washington grad a big man on campus (The Post and Courier)
Andrew Hsu has not yet been on a date or taken his driving test. But he does have three degrees: in neurobiology, biochemistry and chemistry. Last month, just weeks after his 16th birthday, Andrew became the second-youngest person to graduate from the University of Washington and the youngest with a triple degree. ...

Doing Nature One Better: Expanding The Genetic Code In Living Mammalian Cells (Science Daily)
Researchers at the Salk Institute for Biological Studies have developed a novel strategy to expand the natural repertoire of 20 amino acids in mammalian cells, including neurons, and successfully inserted tailor-made amino acids into proteins in these cells. In a powerful demonstration of the method's versatility, they then used unnatural amino acids to determine the operating mechanism of the ...

Fat kills cancer (EurekAlert!)
Researchers in Slovakia have been able to derive mesenchymal stem cells from human adipose, or fat, tissue and engineer them into “suicide genes” that seek out and destroy tumors like tiny homing missiles.

Drug Discovery Research Takes a Leap Forward With Increasing Adoption of Electronic Lab Notebooks (SYS-CON Media)
The European electronic lab notebooks (ELN) market is the scene of much change today as the technology continues to develop rapidly and become more refined with each passing day. Surpassing the capabilities of traditional bound laboratory notebooks, ELNs provide a sophisticated communications platform that enables researchers to share experiment-related information seamlessly, and even improve or ...


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