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Experiments To Annotate All 399 Protein-Coding Genes - Pervasive Transcription, Fewer Boundaries (Medical News Today)
Dr. Alexandre Reymond and colleagues conducted a series of experiments to annotate all 399 protein-coding genes in the ENCODE regions. In doing so, they found that more than half of the genes produced transcripts that contained sequences mapping outside of the known boundaries of these genes. [click link for full article]
(Jun 14, 2007)
DNA Sequences That Bind Proteins To Engage Gene Transcription - More Green Lights (Medical News Today)
Promoters, or DNA sequences that bind proteins to engage gene transcription, were the topic of focus for a team of researchers led by Drs. Zhiping Weng and Richard Myers. Using an integrated computational and experimental approach, they estimated that at least 35% more promoters exist in the human genome than are currently annotated. [click link for full article]
(Jun 14, 2007)
Evolving Notions Of Biological Function (Medical News Today)
Dr. Elliott Margulies and colleagues sequenced the ENCODE regions in 23 mammalian species, aligned the sequences, and identified regions of evolutionary constraint (in other words, sequences that have changed little during evolutionary time). They used four different methods to align the sequences, and three different algorithms to assess constraint. [click link for full article]
(Jun 14, 2007)
Genome Activity In Black And White (Medical News Today)
By integrating ENCODE experimental data, Dr. John Stamatoyannopoulos and his colleagues developed and employed a computational approach to classify genomic regions as "active" or "repressed." Remarkably, they found that the pattern of active versus repressed domains was strikingly conserved between different cell types, and thus may be a universal feature of human genome architecture. [click link ...
(Jun 14, 2007)
Web Resource For Classifying, Storing, Manipulating, And Visualizing TARs - Classified Transcripts (Medical News Today)
The ENCODE Project produced an enormous amount of data on transcriptionally active regions (TARs). Because TARs are difficult to wrangle with, Dr. Mark Gerstein and colleagues constructed the Database of Active Regions and Tools (DART; http://www.dart.gersteinlab.or which is a Web resource for classifying, storing, manipulating, and visualizing TARs. [click link for full article]
(Jun 14, 2007)
Acacia Technologies Licenses Credit Card Fraud Protection Technology to Hugo Boss (Business Wire via Yahoo! Finance)
NEWPORT BEACH, Calif.----Acacia Research Corporation announced today that Financial Systems Innovation LLC, a wholly owned subsidiary of the Acacia Technologies group, a leader in technology licensing, has entered into non-exclusive licenses covering a patent that applies to credit card fraud protection technology with Hugo Boss USA, Inc.
(Jun 14, 2007)
New Techniques Could Spot Alzheimer's Early (iVillage Total Health)
Three groups of researchers are reporting progress on the early detection of Alzheimer's disease -- advances that, if validated, could aid patients and drug developers alike, experts said.
(Jun 14, 2007)
Acacia Technologies Licenses Credit Card Fraud Protection Technology to Hugo Boss (Broadcast Newsroom)
NEWPORT BEACH, Calif.,
(Jun 14, 2007)
'Junk' DNA makes compulsive reading (New Scientist)
A mammoth investigation of human DNA finds it generates far more RNA than thought - so what is the excess for?
(Jun 14, 2007)
Prolexys Pharmaceuticals and Columbia University Researchers Publish Study on Anti-Tumor Properties of a Selective ... (PR Newswire via Yahoo! Finance)
Prolexys Pharmaceuticals and Columbia University announced today a publication describing the properties of the selective small molecule anti-tumor agent, erastin. Prolexys and Columbia applied the company's chemi-proteomics technology to understand the mechanism of action of erastin.
(Jun 14, 2007)
A Novel, High-Throughput Workflow for Discovery and Identification of Serum Carrier Protein-Bound Peptide Biomarker ... (RedNova)
By Lopez, Mary F Mikulskis, Alvydas; Kuzdzal, Scott; Golenko, Eva; Et al Background: Most cases of ovarian cancer are detected at later stages when the 5-year survival is ~15%, but 5-year survival approaches 90% when the cancer is detected early (stage I).
(Jun 14, 2007)
The -256TC Polymorphism in the Apolipoprotein A-II Gene Promoter Is Associated With Body Mass Index and Food Intake in ... (RedNova)
By Corella, Dolores Arnett, Donna K; Tsai, Michael Y; Kabagambe, Edmond K; Et al Background: Apolipoprotein A-II (APOA2) plays an ambiguous role in lipid metabolism, obesity, and atherosclerosis.
(Jun 14, 2007)
$4.5 million donation to aid UAMS research into bone marrow cancer (NWAnews.com)
San Francisco residents Stephen and Nancy Grand have donated $4.5 million to fund cancer research at the University of Arkansas for Medical Sciences, where Stephen Grand has been treated for multiple myeloma, a bone marrow cancer. (Arkansas Democrat-Gazette Northwest Edition)
(Jun 14, 2007)
'Junk' DNA makes compulsive reading (New Scientist)
A mammoth investigation of human DNA finds it generates far more RNA than thought - so what is the excess for?
(Jun 14, 2007)
Aptamers Evolved From Cultured Cancer Cells Reveal Molecular Differences of Cancer Cells in Patient Samples (RedNova)
By Shangguan, Dihua Cao, Zehui Charles; Li, Ying; Tan, Weihong Background: Molecular-level differentiation of neoplastic cells is essential for accurate and early diagnosis, but effective molecular probes for molecular analysis and profiling of neoplastic cells are not yet available.
(Jun 14, 2007)
Indian biotech exports up 47% to $1.2bn (rediff.com)
Exports revenue of Indian biotech industry grew by 47 per cent during 2006-07 at Rs 4,937 crore (USD 1.2 billion), even as the total revenue, including the domestic figures, stood at Rs 8,541 crore (Rs 85.41 billion).
(Jun 14, 2007)
Rosetta Genomics Licenses microRNAs From Rockefeller University (GenomeWeb News)
GenomeWeb Daily News You are not logged in. Existing subscribers login here . New to GenomeWeb Daily News? Register quickly here for your free subscription.
(Jun 14, 2007)
India's biotech exports reach $1.2 bn in 2006-07: survey (IANS via Yahoo! India News)
New Delhi, June 14 (IANS) Revenues from India's biotech industry exports grew by 47 percent to reach $1.2 billion in the financial year ending March 2007, according to a survey.
(Jun 14, 2007)
Screening approach leads to discovery of gene linked to breast cancer (EurekAlert!)
BOSTON -- Using a novel three-part screening process, scientists at Dana-Farber Cancer Institute have identified a gene that is made inappropriately in about a third of all breast cancers.
(Jun 14, 2007)
Casting the molecular net (EurekAlert!)
(Toronto/Heidelberg/Cambridge, June 12, 2007) – Scientists at the Samuel Lunenfeld Research Institute of Mount Sinai Hospital (Canada), European Molecular Biology Laboratory (Germany), and Massachusetts Institute of Technology (USA) have created a new computational method called NetworKIN.
(Jun 14, 2007)
Prolexys Pharmaceuticals and Columbia University Researchers Publish Study on Anti-Tumor Properties of a Selective ... (RedNova)
SALT LAKE CITY, June 14 /PRNewswire/ -- Prolexys Pharmaceuticals and Columbia University announced today a publication describing the properties of the selective small molecule anti-tumor agent, erastin.
(Jun 14, 2007)
Screening Approach Leads To Discovery Of Gene Linked To Breast Cancer (Science Daily)
Using a novel three-part screening process, scientists have identified a gene that is made inappropriately in about a third of all breast cancers. Unlike breast cancer-susceptibility genes such as BRCA1 and BRCA2, the newly identified gene, called IKBKE, is not inherited in a mutated form that increases the risk of developing breast cancer at an early age. Rather, the mutation arises during a ...
(Jun 14, 2007)
Screening approach leads to discovery of gene linked to breast cancer (PhysOrg)
Using a novel three-part screening process, scientists at Dana-Farber Cancer Institute have identified a gene that is made inappropriately in about a third of all breast cancers. The discovery, reached in collaboration with researchers at Brigham and Women's Hospital (BWH) and the Broad Institute of Harvard and MIT, is reported in the June 15, 2007 issue of the journal Cell.
(Jun 14, 2007)
DNA Decoding Landmark (CBS News)
Researchers say they have decoded the first 1% of the human genetic code, and the results already are rewriting the rules of biology.
(Jun 14, 2007)
Human Genome Yields Up More Secrets (MedicineNet.com)
Title: Human Genome Yields Up More Secrets Category: Health News Created: 6/14/2007 2:00:00 AM Last Editorial Review: 6/14/2007
(Jun 14, 2007)
South Korea to Co-Lead Int'l Stem Cell Proteomics Initiative; Commits $138M (GenomeWeb News)
GenomeWeb Daily News You are not logged in. Existing subscribers login here . New to GenomeWeb Daily News? Register quickly here for your free subscription.
(Jun 14, 2007)
AB&C adds KFDunn to its healthcare offerings (The Delaware Business Ledger)
Aloysius Butler & Clark ( http://www.a-b-c.com (AB&C)), healthcare marketing and KFDunnhave merged to form KFDunn Life Sciences, a division of AB&C. Kathleen F. Dunn will serve as the president of the new division.
(Jun 14, 2007)
Celera and Collaborators Discover a Genetic Marker Associated with Severe Coronary Artery Disease (Business Wire via Yahoo! Finance)
ROCKVILLE, Md.----Celera , an Applera Corporation business, and its collaborators at the Cleveland Clinic, University of California, San Francisco , the Scripps Institute, and Queens University, Canada, today announced the publication of a paper describing a novel variant of the LPA gene that is associated with an approximate 3-fold increased risk of severe coronary artery disease .
(Jun 14, 2007)
First Personal Automation System Medical Device for Clinical Labs (RedNova)
Promega Corporation announces availability of the first fully integrated Personal Automation™ System that meets regulatory requirements for clinical diagnostic DNA purification in the United States.
(Jun 14, 2007)
Time for a genetics rethink (The Times of India)
WASHINGTON: An in-depth examination of the human DNA map has turned basic biology concepts upside-down and may even rewrite the book on evolution and some causes of disease, researchers said on Wednesday.
(Jun 14, 2007)
Tiny electronic hearing devices (News-Medical-Net)
More than three decades ago, scientists pursued the then-radical idea of implanting tiny electronic hearing devices in the inner ear to help profoundly deaf people.
(Jun 14, 2007)
Staphylococcus aureus hides out in cells (EurekAlert!)
A major cause of human and animal infections, Staphylococcus aureus bacteria may evade the immune system's defences and dodge antibiotics by climbing into our cells and then lying low to avoid detection. New research in the online open access journal BMC Genomics shows how S. aureus makes itself at home in human lung cells for up to two weeks.
(Jun 14, 2007)
Research finds that circadian rhythms dominate all life functions (EurekAlert!)
FORT COLLINS -- New research from Colorado State University shows that the function of all genes in mammals is based on circadian -- or daily -- rhythms.
(Jun 15, 2007)
BP strikes deal with Synthetic Genomics (CNET)
Companies to study microbes, find ways to exploit certain properties on an industrial scale--work that's part of an emerging field not without controversy.
(Jun 15, 2007)
Pharmacogenomics: Decreasing Drug Toxicity Through Personalized Medicine EHA Congress 2007 (Medical News Today)
Pharmacogenomics offers the promise of individualized drug therapies based on a patient's genetic make-up and that of the tumor cells. Such tailor-made drug regimes hold the promise to further increase survival rates for cancer. [click link for full article]
(Jun 15, 2007)
Scientists Discover Breast Cancer Gene By Mining Genome In A Novel Way (Medical News Today)
US scientists using a novel combination of gene study methods to mine the human genome have shown that a gene called IKBKE is implicated in a third of all breast cancers.The results of their findings are published in the journal Cell. [click link for full article]
(Jun 15, 2007)
Colorado State University Research Finds That Circadian Rhythms Dominate All Life Functions, Play Significant Role In ... (Medical News Today)
New research from Colorado State University shows that the function of all genes in mammals is based on circadian - or daily - rhythms. The study, publishing in PLoS Computational Biology on June 15, refutes the current theory that only 10 percent to 15 percent of all genes were affected by nature's clock. [click link for full article]
(Jun 15, 2007)
Biotech registers 40 % growth in 2006-07, export earnings Rs 4,937 cr (PharmaBiz)
The Indian biotechnology industry has registered a growth of40 per cent with a total revenue of Rs 8,541 crore in 2006-07. The export earnings is Rs 4,937 crore with a 47 per cent growth, according to a survey by BioSpectrum and the Association of Biotechnology-Led Enterprises (ABLE).
(Jun 15, 2007)
Acacia Technologies Licenses Graphical User Interface Technology to Apple Inc. (Business Wire via Yahoo! Finance)
NEWPORT BEACH, Calif.----Acacia Research Corporation announced today that IP Innovation, a wholly owned subsidiary that is a part of the Acacia Technologies group, has entered into a Settlement and License Agreement with Apple Inc. covering patents that relate to graphical user interface systems.
(Jun 15, 2007)
Acacia Technologies Licenses Graphical User Interface Technology to Apple Inc. (Broadcast Newsroom)
NEWPORT BEACH, Calif.,
(Jun 15, 2007)
Invitrogen Launches New Engineered Stem Cell Line (Business Wire via Yahoo! Finance)
CARLSBAD, Calif.----Invitrogen Corporation , a provider of essential life science technologies for disease research and drug discovery, today announced it has launched a new engineered stem cell line that will allow scientists to monitor the pluripotency of human embryonic stem cells without sacrificing those cells.
(Jun 15, 2007)
CLC bio, Aarhus University sign site license agreement for bioinformatics software solution (PharmaBiz)
CLC bio and the Department of Molecular Biology, University of Aarhus, have signed a site license agreement for CLC bio's premier bioinformatics software solution, CLC Combined Workbench, in combination with CLC bio's brand new Educational Package, which offers a solid backbone for bioinformatics courses.
(Jun 15, 2007)
Circadian Rhythms Dominate All Life Functions, According To Study (Science Daily)
New research shows that the function of all genes in mammals is based on circadian -- or daily -- rhythms. The study refutes the current theory that only 10 percent to 15 percent of all genes were affected by nature's clock.
(Jun 15, 2007)
India's biotech exports reach $1.2 bn in 2006-07: survey (SiliconIndia)
New Delhi: Revenues from India's biotech industry exports grew by 47 percent to reach $1.2 billion in the financial year ending March 2007, according to a survey.
(Jun 15, 2007)
BP invests in microbe specialist (CNET)
BP, Synthetic Genomics aim to exploit properties of microbes on an industrial scale; research is part of an emerging field not without controversy.
(Jun 15, 2007)
Exploring the Dark Matter of the Genome (PhysOrg)
Not so long ago, the difficult-to-sequence, highly repetitive, gene-poor DNA found in regions of chromosomes known as heterochromatin was called "junk." Like dark matter in the universe, the true nature of heterochromatin was unknown.
(Jun 15, 2007)
Exploring 'Junk DNA' In The Genome (Science Daily)
"Junk DNA" is what biologists used to call heterochromatin, the highly repetitive, gene-poor DNA concentrated near the centromeres and telomeres of chromosomes. With the publication of version 5.1 of the genome of the fruit fly, Drosophila melanogaster the term "junk" will be heard less often. Heterochromatin, it appears, is crucial to genome maintenance and cell biology.
(Jun 15, 2007)
Clinical Data Implements Luminex xMAP Solution, Expanding Breadth Of Its Genotyping Services (BioresearchOnline)
Clinical Data, Inc. announced today that its Cogenics division, a provider of comprehensive pharmacogenomics and molecular biology services, has implemented a Luminex xMAP multiplexing system to expand its genotyping service offerings and advance its clinical and agricultural genotyping franchises
(Jun 15, 2007)
Tiny Slice Of Genome Reveals Bustling Activity In The Gaps Between Genes - Scientific American (Medical News Today)
The first results from a massive project to exhaustively catalogue all the functions of the human genome reveal a hotbed of activity in the gaps between genes. An international consortium of researchers sifted through 1 percent of the genome looking for pieces of DNA that are copied by the cell or help to control gene activity. [click link for full article]
(Jun 15, 2007)
Oil giant BP invests in microbe specialist (CNET)
BP and Synthetic Genomics aim to exploit microbes on an industrial scale; research is part of an emerging field not without controversy.
(Jun 15, 2007)
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