Bioinformatics News Jun 2007: bioinformatics, genomics, proteomics, microarray, etc.

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Experiments To Annotate All 399 Protein-Coding Genes - Pervasive Transcription, Fewer Boundaries
Dr. Alexandre Reymond and colleagues conducted a series of experiments to annotate all 399 protein-coding genes in the ENCODE regions. In doing so, they found that more than half of the genes produced transcripts that contained sequences mapping outside of the known boundaries of these genes. [click link for full article] (Thu, 14 Jun 2007 08:04:32 GMT)

DNA Sequences That Bind Proteins To Engage Gene Transcription - More Green Lights
Promoters, or DNA sequences that bind proteins to engage gene transcription, were the topic of focus for a team of researchers led by Drs. Zhiping Weng and Richard Myers. Using an integrated computational and experimental approach, they estimated that at least 35% more promoters exist in the human genome than are currently annotated. [click link for full article] (Thu, 14 Jun 2007 08:04:43 GMT)

Evolving Notions Of Biological Function
Dr. Elliott Margulies and colleagues sequenced the ENCODE regions in 23 mammalian species, aligned the sequences, and identified regions of evolutionary constraint (in other words, sequences that have changed little during evolutionary time). They used four different methods to align the sequences, and three different algorithms to assess constraint. [click link for full article] (Thu, 14 Jun 2007 08:04:53 GMT)

Genome Activity In Black And White
By integrating ENCODE experimental data, Dr. John Stamatoyannopoulos and his colleagues developed and employed a computational approach to classify genomic regions as "active" or "repressed." Remarkably, they found that the pattern of active versus repressed domains was strikingly conserved between different cell types, and thus may be a universal feature of human genome architecture. [click link ... (Thu, 14 Jun 2007 08:05:08 GMT)

Web Resource For Classifying, Storing, Manipulating, And Visualizing TARs - Classified Transcripts
The ENCODE Project produced an enormous amount of data on transcriptionally active regions (TARs). Because TARs are difficult to wrangle with, Dr. Mark Gerstein and colleagues constructed the Database of Active Regions and Tools (DART; http://www.dart.gersteinlab.or which is a Web resource for classifying, storing, manipulating, and visualizing TARs. [click link for full article] (Thu, 14 Jun 2007 08:05:15 GMT)

Acacia Technologies Licenses Credit Card Fraud Protection Technology to Hugo Boss
NEWPORT BEACH, Calif.----Acacia Research Corporation announced today that Financial Systems Innovation LLC, a wholly owned subsidiary of the Acacia Technologies group, a leader in technology licensing, has entered into non-exclusive licenses covering a patent that applies to credit card fraud protection technology with Hugo Boss USA, Inc. (Thu, 14 Jun 2007 10:00:00 GMT)

New Techniques Could Spot Alzheimer's Early
Three groups of researchers are reporting progress on the early detection of Alzheimer's disease -- advances that, if validated, could aid patients and drug developers alike, experts said. (Thu, 14 Jun 2007 10:08:23 GMT)

Acacia Technologies Licenses Credit Card Fraud Protection Technology to Hugo Boss
NEWPORT BEACH, Calif., (Thu, 14 Jun 2007 11:23:39 GMT)

'Junk' DNA makes compulsive reading
A mammoth investigation of human DNA finds it generates far more RNA than thought - so what is the excess for? (Thu, 14 Jun 2007 11:47:08 GMT)

Prolexys Pharmaceuticals and Columbia University Researchers Publish Study on Anti-Tumor Properties of a Selective ...
Prolexys Pharmaceuticals and Columbia University announced today a publication describing the properties of the selective small molecule anti-tumor agent, erastin. Prolexys and Columbia applied the company's chemi-proteomics technology to understand the mechanism of action of erastin. (Thu, 14 Jun 2007 12:00:00 GMT)

A Novel, High-Throughput Workflow for Discovery and Identification of Serum Carrier Protein-Bound Peptide Biomarker ...
By Lopez, Mary F Mikulskis, Alvydas; Kuzdzal, Scott; Golenko, Eva; Et al Background: Most cases of ovarian cancer are detected at later stages when the 5-year survival is ~15%, but 5-year survival approaches 90% when the cancer is detected early (stage I). (Thu, 14 Jun 2007 12:21:48 GMT)

The -256TC Polymorphism in the Apolipoprotein A-II Gene Promoter Is Associated With Body Mass Index and Food Intake in ...
By Corella, Dolores Arnett, Donna K; Tsai, Michael Y; Kabagambe, Edmond K; Et al Background: Apolipoprotein A-II (APOA2) plays an ambiguous role in lipid metabolism, obesity, and atherosclerosis. (Thu, 14 Jun 2007 12:22:08 GMT)

$4.5 million donation to aid UAMS research into bone marrow cancer
San Francisco residents Stephen and Nancy Grand have donated $4.5 million to fund cancer research at the University of Arkansas for Medical Sciences, where Stephen Grand has been treated for multiple myeloma, a bone marrow cancer. (Arkansas Democrat-Gazette Northwest Edition) (Thu, 14 Jun 2007 12:54:11 GMT)

'Junk' DNA makes compulsive reading
A mammoth investigation of human DNA finds it generates far more RNA than thought - so what is the excess for? (Thu, 14 Jun 2007 13:04:34 GMT)

Aptamers Evolved From Cultured Cancer Cells Reveal Molecular Differences of Cancer Cells in Patient Samples
By Shangguan, Dihua Cao, Zehui Charles; Li, Ying; Tan, Weihong Background: Molecular-level differentiation of neoplastic cells is essential for accurate and early diagnosis, but effective molecular probes for molecular analysis and profiling of neoplastic cells are not yet available. (Thu, 14 Jun 2007 13:13:33 GMT)

Indian biotech exports up 47% to $1.2bn
Exports revenue of Indian biotech industry grew by 47 per cent during 2006-07 at Rs 4,937 crore (USD 1.2 billion), even as the total revenue, including the domestic figures, stood at Rs 8,541 crore (Rs 85.41 billion). (Thu, 14 Jun 2007 13:51:55 GMT)

Rosetta Genomics Licenses microRNAs From Rockefeller University
GenomeWeb Daily News You are not logged in. Existing subscribers login here . New to GenomeWeb Daily News? Register quickly here for your free subscription. (Thu, 14 Jun 2007 14:29:35 GMT)

India's biotech exports reach $1.2 bn in 2006-07: survey
New Delhi, June 14 (IANS) Revenues from India's biotech industry exports grew by 47 percent to reach $1.2 billion in the financial year ending March 2007, according to a survey. (Thu, 14 Jun 2007 15:57:53 GMT)

Screening approach leads to discovery of gene linked to breast cancer
BOSTON -- Using a novel three-part screening process, scientists at Dana-Farber Cancer Institute have identified a gene that is made inappropriately in about a third of all breast cancers. (Thu, 14 Jun 2007 16:08:39 GMT)

Casting the molecular net
(Toronto/Heidelberg/Cambridge, June 12, 2007) – Scientists at the Samuel Lunenfeld Research Institute of Mount Sinai Hospital (Canada), European Molecular Biology Laboratory (Germany), and Massachusetts Institute of Technology (USA) have created a new computational method called NetworKIN. (Thu, 14 Jun 2007 16:10:12 GMT)

Prolexys Pharmaceuticals and Columbia University Researchers Publish Study on Anti-Tumor Properties of a Selective ...
SALT LAKE CITY, June 14 /PRNewswire/ -- Prolexys Pharmaceuticals and Columbia University announced today a publication describing the properties of the selective small molecule anti-tumor agent, erastin. (Thu, 14 Jun 2007 16:13:39 GMT)

Screening Approach Leads To Discovery Of Gene Linked To Breast Cancer
Using a novel three-part screening process, scientists have identified a gene that is made inappropriately in about a third of all breast cancers. Unlike breast cancer-susceptibility genes such as BRCA1 and BRCA2, the newly identified gene, called IKBKE, is not inherited in a mutated form that increases the risk of developing breast cancer at an early age. Rather, the mutation arises during a ... (Thu, 14 Jun 2007 17:07:26 GMT)

Screening approach leads to discovery of gene linked to breast cancer
Using a novel three-part screening process, scientists at Dana-Farber Cancer Institute have identified a gene that is made inappropriately in about a third of all breast cancers. The discovery, reached in collaboration with researchers at Brigham and Women's Hospital (BWH) and the Broad Institute of Harvard and MIT, is reported in the June 15, 2007 issue of the journal Cell. (Thu, 14 Jun 2007 17:49:08 GMT)

DNA Decoding Landmark
Researchers say they have decoded the first 1% of the human genetic code, and the results already are rewriting the rules of biology. (Thu, 14 Jun 2007 18:26:47 GMT)

Human Genome Yields Up More Secrets
Title: Human Genome Yields Up More Secrets Category: Health News Created: 6/14/2007 2:00:00 AM Last Editorial Review: 6/14/2007 (Thu, 14 Jun 2007 19:30:16 GMT)

South Korea to Co-Lead Int'l Stem Cell Proteomics Initiative; Commits $138M
GenomeWeb Daily News You are not logged in. Existing subscribers login here . New to GenomeWeb Daily News? Register quickly here for your free subscription. (Thu, 14 Jun 2007 19:30:24 GMT)

AB&C adds KFDunn to its healthcare offerings
Aloysius Butler & Clark ( http://www.a-b-c.com (AB&C)), healthcare marketing and KFDunnhave merged to form KFDunn Life Sciences, a division of AB&C. Kathleen F. Dunn will serve as the president of the new division. (Thu, 14 Jun 2007 20:03:19 GMT)

Celera and Collaborators Discover a Genetic Marker Associated with Severe Coronary Artery Disease
ROCKVILLE, Md.----Celera , an Applera Corporation business, and its collaborators at the Cleveland Clinic, University of California, San Francisco , the Scripps Institute, and Queens University, Canada, today announced the publication of a paper describing a novel variant of the LPA gene that is associated with an approximate 3-fold increased risk of severe coronary artery disease . (Thu, 14 Jun 2007 20:05:00 GMT)

First Personal Automation System Medical Device for Clinical Labs
Promega Corporation announces availability of the first fully integrated Personal Automation™ System that meets regulatory requirements for clinical diagnostic DNA purification in the United States. (Thu, 14 Jun 2007 20:24:47 GMT)

Time for a genetics rethink
WASHINGTON: An in-depth examination of the human DNA map has turned basic biology concepts upside-down and may even rewrite the book on evolution and some causes of disease, researchers said on Wednesday. (Thu, 14 Jun 2007 21:17:34 GMT)

Tiny electronic hearing devices
More than three decades ago, scientists pursued the then-radical idea of implanting tiny electronic hearing devices in the inner ear to help profoundly deaf people. (Thu, 14 Jun 2007 22:34:18 GMT)

Staphylococcus aureus hides out in cells
A major cause of human and animal infections, Staphylococcus aureus bacteria may evade the immune system's defences and dodge antibiotics by climbing into our cells and then lying low to avoid detection. New research in the online open access journal BMC Genomics shows how S. aureus makes itself at home in human lung cells for up to two weeks. (Thu, 14 Jun 2007 23:08:10 GMT)

Research finds that circadian rhythms dominate all life functions
FORT COLLINS -- New research from Colorado State University shows that the function of all genes in mammals is based on circadian -- or daily -- rhythms. (Fri, 15 Jun 2007 00:10:12 GMT)

BP strikes deal with Synthetic Genomics
Companies to study microbes, find ways to exploit certain properties on an industrial scale--work that's part of an emerging field not without controversy. (Fri, 15 Jun 2007 01:20:39 GMT)

Pharmacogenomics: Decreasing Drug Toxicity Through Personalized Medicine EHA Congress 2007
Pharmacogenomics offers the promise of individualized drug therapies based on a patient's genetic make-up and that of the tumor cells. Such tailor-made drug regimes hold the promise to further increase survival rates for cancer. [click link for full article] (Fri, 15 Jun 2007 07:06:12 GMT)

Scientists Discover Breast Cancer Gene By Mining Genome In A Novel Way
US scientists using a novel combination of gene study methods to mine the human genome have shown that a gene called IKBKE is implicated in a third of all breast cancers.The results of their findings are published in the journal Cell. [click link for full article] (Fri, 15 Jun 2007 08:04:11 GMT)

Colorado State University Research Finds That Circadian Rhythms Dominate All Life Functions, Play Significant Role In ...
New research from Colorado State University shows that the function of all genes in mammals is based on circadian - or daily - rhythms. The study, publishing in PLoS Computational Biology on June 15, refutes the current theory that only 10 percent to 15 percent of all genes were affected by nature's clock. [click link for full article] (Fri, 15 Jun 2007 08:06:58 GMT)

Biotech registers 40 % growth in 2006-07, export earnings Rs 4,937 cr
The Indian biotechnology industry has registered a growth of40 per cent with a total revenue of Rs 8,541 crore in 2006-07. The export earnings is Rs 4,937 crore with a 47 per cent growth, according to a survey by BioSpectrum and the Association of Biotechnology-Led Enterprises (ABLE). (Fri, 15 Jun 2007 09:49:12 GMT)

Acacia Technologies Licenses Graphical User Interface Technology to Apple Inc.
NEWPORT BEACH, Calif.----Acacia Research Corporation announced today that IP Innovation, a wholly owned subsidiary that is a part of the Acacia Technologies group, has entered into a Settlement and License Agreement with Apple Inc. covering patents that relate to graphical user interface systems. (Fri, 15 Jun 2007 10:00:00 GMT)

Acacia Technologies Licenses Graphical User Interface Technology to Apple Inc.
NEWPORT BEACH, Calif., (Fri, 15 Jun 2007 11:23:29 GMT)

Invitrogen Launches New Engineered Stem Cell Line
CARLSBAD, Calif.----Invitrogen Corporation , a provider of essential life science technologies for disease research and drug discovery, today announced it has launched a new engineered stem cell line that will allow scientists to monitor the pluripotency of human embryonic stem cells without sacrificing those cells. (Fri, 15 Jun 2007 12:00:00 GMT)

CLC bio, Aarhus University sign site license agreement for bioinformatics software solution
CLC bio and the Department of Molecular Biology, University of Aarhus, have signed a site license agreement for CLC bio's premier bioinformatics software solution, CLC Combined Workbench, in combination with CLC bio's brand new Educational Package, which offers a solid backbone for bioinformatics courses. (Fri, 15 Jun 2007 12:34:03 GMT)

Circadian Rhythms Dominate All Life Functions, According To Study
New research shows that the function of all genes in mammals is based on circadian -- or daily -- rhythms. The study refutes the current theory that only 10 percent to 15 percent of all genes were affected by nature's clock. (Fri, 15 Jun 2007 13:08:07 GMT)

India's biotech exports reach $1.2 bn in 2006-07: survey
New Delhi: Revenues from India's biotech industry exports grew by 47 percent to reach $1.2 billion in the financial year ending March 2007, according to a survey. (Fri, 15 Jun 2007 13:13:32 GMT)

BP invests in microbe specialist
BP, Synthetic Genomics aim to exploit properties of microbes on an industrial scale; research is part of an emerging field not without controversy. (Fri, 15 Jun 2007 13:50:39 GMT)

Exploring the Dark Matter of the Genome
Not so long ago, the difficult-to-sequence, highly repetitive, gene-poor DNA found in regions of chromosomes known as heterochromatin was called "junk." Like dark matter in the universe, the true nature of heterochromatin was unknown. (Fri, 15 Jun 2007 14:03:58 GMT)

Exploring 'Junk DNA' In The Genome
"Junk DNA" is what biologists used to call heterochromatin, the highly repetitive, gene-poor DNA concentrated near the centromeres and telomeres of chromosomes. With the publication of version 5.1 of the genome of the fruit fly, Drosophila melanogaster the term "junk" will be heard less often. Heterochromatin, it appears, is crucial to genome maintenance and cell biology. (Fri, 15 Jun 2007 14:06:47 GMT)

Clinical Data Implements Luminex xMAP Solution, Expanding Breadth Of Its Genotyping Services
Clinical Data, Inc. announced today that its Cogenics division, a provider of comprehensive pharmacogenomics and molecular biology services, has implemented a Luminex xMAP multiplexing system to expand its genotyping service offerings and advance its clinical and agricultural genotyping franchises (Fri, 15 Jun 2007 15:32:04 GMT)

Tiny Slice Of Genome Reveals Bustling Activity In The Gaps Between Genes - Scientific American
The first results from a massive project to exhaustively catalogue all the functions of the human genome reveal a hotbed of activity in the gaps between genes. An international consortium of researchers sifted through 1 percent of the genome looking for pieces of DNA that are copied by the cell or help to control gene activity. [click link for full article] (Fri, 15 Jun 2007 16:04:36 GMT)

Oil giant BP invests in microbe specialist
BP and Synthetic Genomics aim to exploit microbes on an industrial scale; research is part of an emerging field not without controversy. (Fri, 15 Jun 2007 17:05:39 GMT)

NIH Awards Nearly $21 Million To Fund Cutting-Edge Research Equipment
The National Center for Research Resources (NCRR), a part of the National Institutes of Health (NIH), has announced that it will provide $20.65 million for 14 High-End Instrumentation (HEI) grants that will fund cutting-edge equipment required to advance biomedical research. [click link for full article] (Fri, 15 Jun 2007 20:04:18 GMT)

Chr. Hansen teams up with CLC bio for identifying new bacteria genes
The Denmark-based Chr Hansen A/S (Christian Hansen Company), natural ingredients health products supplier, has entered into a tie up with CLC bio, the leading bioinformatics solution provider and Roskilde University in an effort to understand the genetic make-up of bacteria to improve performance of probiotic products. (Sat, 16 Jun 2007 02:34:24 GMT)

Research Finds That Circadian Rhythms Dominate All Life Functions, Play Significant Role In Metabolism
New research from Colorado State University shows that the function of all genes in mammals is based on circadian or daily rhythms. The study, publishing in PLoS Computational Biology on June 15, refutes the current theory that only 10 percent to 15 percent of all genes were affected by nature's clock. [click link for full article] (Sat, 16 Jun 2007 07:07:25 GMT)

Human genome blue print view challenged
An international research consortium published a set of papers that promise to reshape our understanding of how the human genome functions. (Sat, 16 Jun 2007 08:34:40 GMT)

Scientist at CSU making strides in biological research
A Colorado State University scientist has broken new ground in biological research that could help scientists understand weight loss, jet lag and sleep patterns. (Sat, 16 Jun 2007 11:17:42 GMT)

UK Aging Research Receives Major Boost With 5.9 Million Pound Award
Research into ageing has received a major boost thanks to a 5.9 million pound Strategic Award from the Wellcome Trust, the UK's largest medical research charity. It is hoped that the award will help strengthen the UK's position in this rapidly developing field of research and will help scientists understand what it means to age. [click link for full article] (Sat, 16 Jun 2007 19:04:12 GMT)

1-week DNA workshop is for science teachers
High school science teachers can learn about introducing students to the cutting-edge, high-demand field of DNA analysis during a workshop next week at the University of Indianapolis. (Sat, 16 Jun 2007 19:18:55 GMT)

Oldest varsity to be Bihar’s newest one
NALANDA - WORLD HERITAGE SITE?... Nalanda, one of the world’s oldest universities, is being revived by the Bihar government. (Sat, 16 Jun 2007 19:53:26 GMT)

PG education losing sheen and lustre?
The number of aspirants applying for admission to the PG courses in Patna University is any indication of the postgraduate education in Bihar. (Sat, 16 Jun 2007 22:06:29 GMT)

Surprises Related To Organization And Function Of Human Genetic Blueprint Uncovered
The ENCyclopedia Of DNA Elements (ENCODE), an international research consortium organised by the National Human Genome Research Institute (NHGRI), part of the National Institutes of Health (NIH), has published the results of its exhaustive, four-year effort to build a "parts list" of all biologically functional elements in 1 percent of the human genome in the journal Nature. [click link for full ... (Sun, 17 Jun 2007 02:04:13 GMT)

Bayer HealthCare AG Renews and Expands its License for Ariadne Pathway Studio and MedScan Technology
Ariadne today announced that Bayer HealthCare AG will renew and expand its license for Ariadne Pathway Studio software powered by MedScan Technology till the end of 2010 to use for pathway research, toxicology studies and microarray data analysis. (Sun, 17 Jun 2007 07:01:00 GMT)

Mayo Clinic Researchers Use 'Genomic Pathway' To Predict Parkinson's
Findings detect 90-fold increased risk of developing disease; predict age of onsetA new Mayo Clinic study, published June 15 in PLoS Genetics, provides strong evidence that the joint effects of common DNA variations in several genes that encode proteins within a well-defined biological pathway la [click link for full article] (Sun, 17 Jun 2007 07:04:12 GMT)

Powering Up: Livewire Lifescience Signs on First Customer
RALEIGH — Livewire Lifescience Solutions Inc., a three-person company founded November last year, has landed a customer for its Linux-based high performance computer clusters. (Sun, 17 Jun 2007 07:35:08 GMT)

Breathing easier
Trees, grass, pollen, pork, beef, dairy products, most animals, insects – Susie Beetham is allergic to just about everything. (Sun, 17 Jun 2007 10:06:28 GMT)

Program lures new scientists to poor nations
A new program launched in Asia is encouraging some of the world’s best and brightest young scientists to consider careers helping developing nations, instead of taking jobs focused on the developed world. (Sun, 17 Jun 2007 13:57:07 GMT)

Deobagkar appointed Goa University V-C
PROF Dileep Deobagkar of the University of Pune has been appointed as Vice-Chancellor of Goa University. He will take over from V-C PS Zacharias on June 20. Deobagkar is a Shivaji University alumni and has done his PhD in molecular biology from Indian Institute of Science, Bangalore. He joined the UoP in 1985 and is director, Institute of Bioinformatics & Biotechnology. He has taught subjects in ... (Sun, 17 Jun 2007 18:53:26 GMT)

DNA results to be added to family tree Web sites
For less than $200 (150 EUR) and a cheek-swiped cotton swab, amateur historians will soon add DNA results to family tree Web sites. The rapidly growing field of online genealogical searches is expanding to genetic testing, courtesy of a new partnership between the Internet's largest family history Web site, Ancestry.com , and Sorenson Genomics , a privately held DNA research firm. (Sun, 17 Jun 2007 22:41:42 GMT)

Link between restless legs syndrome and hypertension
An international team of researchers, led by Emory University clinician scientists, has found evidence that people suffering from moderate to severe cases of restless legs syndrome (RLS) are at significantly increased risk for developing hypertension. (Mon, 18 Jun 2007 00:19:07 GMT)

IntegraGen Becomes First Certified French Service Provider for Illumina GoldenGate and Infinium Genotyping
SAN DIEGO----Concurrent with the annual European Human Genetics Conference in Nice, France, Illumina, Inc. announced today that IntegraGen SA, a personalized healthcare company focused on the development and commercialization of molecular diagnostic tests for complex diseases and provider of genetic services, has received Illumina Certified Service Provider (CSPro) certification for GoldenGate® ... (Mon, 18 Jun 2007 04:00:00 GMT)

From Leftovers to Energy
Scientists develop microbes that convert food scraps into energy. (Mon, 18 Jun 2007 04:01:54 GMT)

IntegraGen Becomes First Certified French Service Provider for Illumina GoldenGate and Infinium Genotyping
Concurrent with the annual European Human Genetics Conference in Nice, France, Illumina, ( Nachrichten ) Inc. (NASDAQ:ILMN) announced today that IntegraGen SA, a personalized healthcare company focused on the development and commercialization of molecular diagnostic tests for complex diseases and provider of genetic services, has received Illumina Certified Service Provider (CSPro â„¢ ) ... (Mon, 18 Jun 2007 04:06:34 GMT)

(2º) Illumina GoldenGate and Infinium Genotyping
IntegraGen Becomes First Certified French Service Provider for . (Mon, 18 Jun 2007 04:25:02 GMT)

Noticias Infobolsa / Titulares
IntegraGen Becomes First Certified French Service Provider for . Illumina GoldenGate and Infinium Genotyping Illumina GoldenGate and Infinium Genotyping 18/06/2007 04:00:00 Business Wire US4523271090 Concurrent with the annual European Human Genetics Conference in Nice, France, Illumina, Inc. (Mon, 18 Jun 2007 04:25:12 GMT)

Ancestry.com adding DNA test results to help unlock family history
WASHINGTON (AP) - For less than $200 US and a cheek-swiped cotton swab, amateur historians will soon be able to add DNA results to family tree websites. (Mon, 18 Jun 2007 04:27:00 GMT)

Ancestry.com adding DNA test results
For less than $200 and a cheek-swiped cotton swab, amateur historians will soon be able to add DNA results to family tree Web sites. (Mon, 18 Jun 2007 04:32:45 GMT)

Ancestry.com adding DNA test results
For less than $200 and a cheek-swiped cotton swab, amateur historians will soon be able to add DNA results to family tree Web sites. The rapidly growing field of online genealogical searches is expanding to genetic testing, courtesy of a new partnership between the Internet's largest family history Web site, Ancestry.com, and Sorenson Genomics, a privately held DNA research firm. Sorenson and ... (Mon, 18 Jun 2007 04:42:00 GMT)

Healthy business: Medical research builds local fitness industry
The age-old notion that exercise is good for you may not be rocket science. But the stream of Genomics Age research explaining the hows and whys of fitness while uncovering unexpected new benefits has several fitness-related business opportunities poised for liftoff. (Mon, 18 Jun 2007 04:50:59 GMT)

Biotech association opens office at UAlbany
The New York Biotechnology Association has opened an office at the Center for Functional Genomics on the University at Albany's East Campus. (Mon, 18 Jun 2007 05:14:02 GMT)

Biotech progress report
According to the Arizona's Bioscience Roadmap, commissioned and coordinated by the Flinn Foundation, there are four main strategies the state needs to focus on to develop a strong bioscience hub. Here are those strategies and how Arizona fared in the second quarter of 2007. (Mon, 18 Jun 2007 05:18:54 GMT)

Codon Devices to double presence in Cambridge
Codon Devices Inc. plans to relocate more than half of its staff members to a separate building in Cambridge next month in anticipation of major growth. (Mon, 18 Jun 2007 05:41:53 GMT)

INTERVIEW Innogenetics targets data on partner for therapeutics ops in August
BRUSSELS (Thomson Financial) - Belgian biotechnology group Innogenetics NV ( Nachrichten ) expects to make concrete progress in its search for a strategic partner for its ailing therapeutics business in August, with a result geared to towards increasing shareholder value, said chief executive Frank Morich. (Mon, 18 Jun 2007 05:51:26 GMT)

DNA takes genealogy to new level
In less than three weeks, people will be able to find distant relatives by clicking a mouse. And they can be sure that their supposed family members are related to them because instead of using old documents, people will locate their relatives through DNA tests. (Mon, 18 Jun 2007 06:28:50 GMT)

Indiana Noteworthy
The Canary Foundation presented a team of researchers from Indiana University and Purdue University with a $25,000 bioinformatics research award. (Mon, 18 Jun 2007 06:58:49 GMT)

The Cytoprotective Chaperone, Clusterin, Is Associated With Docetaxel-Resistance In Prostate Cancer Cell Lines
UroToday.com - Researchers stated that the efficacy of docetaxel chemotherapy in hormone refractory prostate cancer (HRPC) is limited by de novo drug resistance or the development of the cellular-resistant phenotype during treatment. [click link for full article] (Mon, 18 Jun 2007 07:07:33 GMT)

Differential Expression Of Ral Gtpases And Their Effectors In Bladder Cancer
UroToday.com - By way of introduction, transformation of human cells by Ras depends on activation of the Ral GTPase pathway; however, no report exists which explores the expression state of these key mediators and their effectors in human cancer. Steven Smith, Gary Oxford, and Dan Theodorescu, MD, PhD. from the University of Virginia. [click link for full article] (Mon, 18 Jun 2007 07:08:43 GMT)

3 degrees aren't enough for 16-year-old UW grad
Andrew Hsu has not yet been on a date or taken his driving test. But he does have three degrees — in neurobiology, biochemistry and... (Mon, 18 Jun 2007 07:08:55 GMT)

India's biotech export touches $1.2 billion
India's export revenue from biotechnology grew by 47 per cent to reach to 1.2 billion dollars in the financial year ended March 2007, a survey said. (Mon, 18 Jun 2007 07:22:05 GMT)

AnaSpec Introduces Twenty-Six New Catalog Peptides AnaSpec Inc. Posted on: 15 Jun 07
This week AnaSpec, one of the world’s largest providers of custom and catalog peptides, introduced twenty-six (26) new peptides for drug discovery research. (Mon, 18 Jun 2007 08:45:58 GMT)

Ancestry.com adding DNA results
For less than $200 and a cheek-swiped cotton swab, amateur historians will soon be able to add DNA results to family tree Web sites. The rapidly growing field of online genealogical searches is expanding to genetic testing, courtesy of a new partnership between the Internet's largest family history Web site, Ancestry.com, and Salt Lake City-based Sorenson Genomics, a privately held DNA research ... (Mon, 18 Jun 2007 10:32:47 GMT)

Staphylococcus Aureus Hides Out In Cells
A major cause of human and animal infections, Staphylococcus aureus bacteria may evade the immune system's defences and dodge antibiotics by climbing into our cells and then lying low to avoid detection. New research in the online open access journal BMC Genomics shows how S. aureus makes itself at home in human lung cells for up to two weeks. [click link for full article] (Mon, 18 Jun 2007 11:04:27 GMT)

Ancestry.com Enters DNA Genealogy Field Through Exclusive Partnership With Sorenson Genomics
A new partnership seeks to reunite families through science. The Generations Network, parent company of Ancestry.com, has announced it will combine its unrivaled collection of online family trees and historical documents with Sorenson Genomics' precision ancestral DNA testing. (Mon, 18 Jun 2007 12:08:00 GMT)

Family Trees 2.0
In January, Bob Warden of Santa Rosa, Calif., received a rare e-mail from his 25-year-old nephew Christian. A link in the message directed him to Geni.com, a social-networking site where Christian had assembled a virtual family tree with names, pictures, birth dates, and e-mail addresses of the Warden clan, mapped out in pink and blue boxes. But Uncle Bob's help was needed: The tree was missing ... (Mon, 18 Jun 2007 12:08:41 GMT)

New Findings Challenge Beliefs About DNA
By Rick Weiss WASHINGTON -- The first concerted effort to understand all the inner workings of the DNA molecule is overturning a host of long- held assumptions about the nature of genes and their role in human health and evolution, scientists reported Wednesday. (Mon, 18 Jun 2007 12:17:26 GMT)

DNAPrint(R) Genomics Releases EuroDNA(TM) 2.0
DNAPrint® Genomics today announced the release of the long-awaited EuroDNA(TM) 2.0 (http://ancestrybydna.com/welc ancestry indicator, which complements DNAPrint®'s powerful line of ancestry testing products. (Mon, 18 Jun 2007 12:23:00 GMT)

Geneaology Site To Include DNA Results Online
The rapidly growing field of online genealogical searches is expanding to genetic testing, courtesy of a new partnership between the Internet's largest family history Web site, Ancestry.com, and Sorenson Genomics, a privately held DNA research firm. (Mon, 18 Jun 2007 13:10:00 GMT)

Agilent Technologies Expands Informatics Portfolio with Electronic Notebook for Life Sciences, Chemical Analysis After ...
Agilent Technologies Inc. ( Nachrichten ) (NYSE:A) today announced it has acquired the Klee Group ' s Kalabie Electronic Laboratory Notebook (ELN). The focus for this product, which is Agilent ' s first electronic notebook, will be on the pharmaceutical market and some chemical applications. (Mon, 18 Jun 2007 13:23:54 GMT)

Intel and IRCSET in research link-up
Intel and the Irish Research Council for Science, Engineering and Technology (IRCSET) are co-operating on a research project to help older people. (Mon, 18 Jun 2007 14:09:40 GMT)

Gene Logic Collaboration Reveals Genomic Predictors of Parkinson's Disease
Gene Logic Inc. ( Nachrichten ) (NASDAQ:GLGC) announced today that a collaborative study between its Genomics Division and Mayo Clinic has found biomarkers that predict susceptibility to Parkinson ' s disease and age of disease onset. (Mon, 18 Jun 2007 15:24:42 GMT)

Frost & Sullivan Honored Companies for Innovative Technologies
Frost & Sullivan recognized companies for innovation and leadership at the annual Frost & Sullivan Excellence in Emerging Technologies Awards Banquet held in Newport Beach, California last week. (Mon, 18 Jun 2007 17:10:00 GMT)

Ludesi CEO to Lecture on Quality Control & Reproducibility in 2D Gel Image Analysis at NIH BIO-TRAC Training Courses
Ludesi AB, developer and provider of the world's leading 2D Gel Image Analysis Service, today announced that its Founder and CEO Ola Forsstrom-Olsson will lecture at the upcoming BIO-TRAC Biotechnology Training Courses at the National Institutes of Health on June 25-29, 2007. Mr. (Mon, 18 Jun 2007 17:10:03 GMT)

A Light On The Dark Matter Of The Genome
Not so long ago, the difficult-to-sequence, highly repetitive, gene-poor DNA found in regions of chromosomes known as heterochromatin was called "junk." Like dark matter in the universe, the true nature of heterochromatin was unknown (Mon, 18 Jun 2007 17:32:04 GMT)

ENCODE Map Changes View Of The Human Genome Landscape
Since the completion of the Human Genome Project in 2003, research efforts have been aimed at analyzing the functions of various sequences in the genome, using both experimental and computational strategies. The June issue of Genome Research (http://www.genome. [click link for full article] (Mon, 18 Jun 2007 18:04:19 GMT)

16-year-old graduates Univ of Washington with 3 degrees
Andrew Hsu has not yet been on a date or taken his driving test. (Mon, 18 Jun 2007 21:31:53 GMT)

Discovery of IKBKE gene linked to breast cancer
Using a novel three-part screening process, scientists at Dana-Farber Cancer Institute have identified a gene that is made inappropriately in about a third of all breast cancers. (Mon, 18 Jun 2007 23:35:06 GMT)

STEM CELLS(R) and Invitrogen Present the 2nd Annual STEM CELLS(R) Young Investigator Award
The senior editors of the journal STEM CELLS(R) today announced Noatsugu Haraguchi, MD, PhD, from Kyushu University in Japan, as the winner of the 2nd Annual STEM CELLS(R) Young Investigator Award, sponsored by Invitrogen. The $10,000 award is given to a scientist age 40 or younger who is the principal author of the qualifying STEM CELLS(R) paper from the past year judged to be most important by ... (Tue, 19 Jun 2007 02:01:00 GMT)

On the Brink of Artificial Life
Craig Venter says success is near, but critics blast efforts to patent synthetic organisms (Tue, 19 Jun 2007 04:27:04 GMT)

Circadian rhythms and genetics
New research from Colorado State University shows that the function of all genes in mammals is based on circadian -- or daily -- rhythms. The study, publishing in PLoS Computational Biology on June 15, refutes the current theory that only 10 percent to 15 percent of all genes were affected by nature's clock. (Tue, 19 Jun 2007 04:49:26 GMT)

Small product, big impact
When Integrated DNA Technologies moved to Coralville’s Commercial Park in 1989, the building was 10,293 square feet. (Tue, 19 Jun 2007 08:36:39 GMT)

Agilent Technologies Expands Informatics Portfolio with Electronic Notebook For Life Sciences, Chemical Analysis After ...
Agilent Technologies Inc.recently announced it has acquired the Klee Group's Kalabie Electronic Laboratory Notebook (ELN). The focus for this product, which is Agilent's first electronic notebook, will be on the pharmaceutical market and some chemical applications (Tue, 19 Jun 2007 09:18:01 GMT)

DNA results to be added to family tree Web sites
For less than $200 (150 EUR) and a cheek-swiped cotton swab, amateur historians will soon add DNA results to family tree Web sites. The rapidly growing field of online genealogical searches is expanding to genetic testing, courtesy of a new partnership between the Internet's largest family history Web site, Ancestry.com, and Sorenson Genomics, a privately held DNA research firm. Sorenson and ... (Tue, 19 Jun 2007 09:52:29 GMT)

Helicos BioSciences Strengthens Executive Management Team in Preparation for Commercial Launch
CAMBRIDGE, Mass.----Helicos BioSciences Corporation announced today the addition of new members to its executive management team as a key step in building a commercial organization. (Tue, 19 Jun 2007 11:00:00 GMT)

The Power Of Networks Lets Scientists Unravel The Complex Control Of Biological Processes
Scientists at the Samuel Lunenfeld Research Institute of Mount Sinai Hospital (Canada), European Molecular Biology Laboratory (Germany), and Massachusetts Institute of Technology (USA) have created a new computational method called NetworKIN. This method uses biological networks to better identify relationships between molecules. [click link for full article] (Tue, 19 Jun 2007 11:04:12 GMT)

Applied Biosystems Opens New Application Support Center
FOSTER CITY, Calif.----Applied Biosystems , an Applera Corporation business, today announced the opening of an Application Support Center located at its research and development headquarters in Foster City, Calif. (Tue, 19 Jun 2007 11:30:00 GMT)

Monarch LifeSciences Enters Agreement With GeneGo to Provide Pathway Analysis Services Using 1-2-3 Workflow
GeneGo, Inc., the leading systems biology tools company, announced today that Monarch LifeSciences will be offering pathway analysis add on services to their customers. (Tue, 19 Jun 2007 12:00:00 GMT)

STEM CELLS(R) and Invitrogen Present the 2nd Annual STEM CELLS(R) Young Investigator Award
CAIRNS, Australia----The senior editors of the journal STEM CELLS® today announced Noatsugu Haraguchi, MD, PhD, from Kyushu University in Japan, as the winner of the 2nd Annual STEM CELLS® Young Investigator Award, sponsored by Invitrogen. (Tue, 19 Jun 2007 12:01:00 GMT)

True nature of heterochromatin revealed
Not so long ago, the difficult-to-sequence, highly repetitive, gene-poor DNA found in regions of chromosomes known as heterochromatin was called "junk." Like dark matter in the universe, the true nature of heterochromatin was unknown. (Tue, 19 Jun 2007 12:19:37 GMT)

deCODE genetics to Webcast Presentations at its Annual R&D Event
deCODE genetics today announced that it will webcast live the presentations at the company's annual R&D event being held in Reykjavik on Monday, June 25, 2007. (Tue, 19 Jun 2007 12:47:00 GMT)

Roche to buy NimbleGen for $272.5M
NimbleGen Systems Inc., a Madison company that had filed for an initial public offering of common stock in March, will instead be acquired by Swiss life sciences and pharmaceutical giant Roche. (Tue, 19 Jun 2007 15:13:19 GMT)

First prize in DSM Science & Technology Awards (South) 2007 goes to Swiss researcher Bernd Bodenmiller
Swiss researcher Bern Bodenmiller today won the first prize in the DSM Science & Technology Awards 2007. An international judging committee, chaired by Dr Manfred Eggersdorfer, R&D Director at DSM Nutritional Products, selected Bernd Bodenmiller, who will obtain his doctorate from the Swiss Federal Institute of Technology (ETH) Zurich in November 2007 for his PhD thesis entitled 'Quantitative ... (Tue, 19 Jun 2007 15:20:00 GMT)

First prize in DSM Science & Technology Awards (South) 2007 goes to Swiss researcher Bernd Bodenmiller
Swiss researcher Bern Bodenmiller today won the first prize in the DSM Science & Technology Awards (South) 2007. An international judging committee, chaired by Dr Manfred Eggersdorfer, R&D Director at DSM Nutritional Products, selected Bernd Bodenmiller, who will obtain his doctorate from the Swiss Federal Institute of Technology (ETH) Zurich in November 2007 for his PhD thesis entitled ... (Tue, 19 Jun 2007 15:36:00 GMT)

Monarch LifeSciences Enters Agreement With GeneGo To Provide Pathway Analysis Services Using 1-2-3 Workflow
GeneGo, Inc., a systems biology tools company, announced today that Monarch LifeSciences will be offering pathway analysis add on services to their customers (Tue, 19 Jun 2007 16:03:44 GMT)

The 21st century CAVEman
Over the past decade the medical world has been the beneficiary of some of the most promising advances in virtual reality technologies, transforming the lives of patients and medical students as well as equipping doctors with more efficient tools and means of treatment. (Tue, 19 Jun 2007 16:10:29 GMT)

BP's New Design
A deal with a private biotech company offers great promise. (Tue, 19 Jun 2007 16:25:00 GMT)

Ryoka Systems and BiosolveIT Sign Comprehensive Distribution Contract
TOKYO & ST. AUGUSTIN, Germany----Ryoka Systems Inc. in Tokyo, Japan has signed a software distribution agreement with renowned cheminformatics provider BioSolveIT GmbH headquartered in St. (Tue, 19 Jun 2007 16:26:00 GMT)

Studying Genes of Desert Fruit Flies
Researchers at the University of Arkansas and University of Nevada-Las Vegas will study the genetics of fruit flies in desert habitats to determine how they developed the ability to survive under stressful conditions. (Tue, 19 Jun 2007 16:34:08 GMT)

Monarch Life Sciences to Offer GeneGo's Proteomics Data Services as Add-On
GenomeWeb Daily News You are not logged in. Existing subscribers login here . New to GenomeWeb Daily News? Register quickly here for your free subscription. (Tue, 19 Jun 2007 19:29:37 GMT)

Work with Universities
Our research extends beyond the boundaries of our labs. We work with our colleagues in university labs and regularly publish papers with them. We also foster collaborative relationships through Fellowships, grants and shared research programs. (Tue, 19 Jun 2007 20:18:51 GMT)

Local News Fresh blood at Genesis Genomics
As Thunder Bay's economy continues its drive towards diversification, a local company is making a splash with the hiring of a new leader. (Tue, 19 Jun 2007 21:30:01 GMT)

Many of the areas of the human genome previously thought to be deserts are in fact teeming with life
Most known human genes in the genome map are still incompletely annotated, says Professor Alexandre Reymond, from the Centre for Integrative Genomics, University of Lausanne, Switzerland and the Department of Genetic Medicine, University of Geneva, Geneva, Switzerland. (Wed, 20 Jun 2007 00:34:12 GMT)

Roche set to buy NimbleGen for $272.5 million
Roche has agreed to buy US microarray maker NimbleGen for $272.5 million in order to expand its presence in the genomics research market. (Wed, 20 Jun 2007 01:27:13 GMT)

Roche acquires NimbleGen to enter high-growth research microarrray market
Roche and NimbleGen Systems Inc. have signed a definitive agreement under which Roche will acquire 100 per cent of NimbleGen, a privately held, Madison, Wisconsin, USA-based company active in high-density DNA microarrays. (Wed, 20 Jun 2007 04:34:05 GMT)

Growing Demand for Advanced Data Handling Tools in Drug Discovery Creates Growth Potential for Bioinformatics
The European bioinformatics industry is competing in a growing market, which is dominated by a few large vendors. Bioinformatics has varied applications in the drug discovery market, including proteomic, genomic and information manipulation applications. (Wed, 20 Jun 2007 07:01:00 GMT)

Screening Approach Leads To Discovery Of Gene Linked To Breast Cancer
Using a novel three-part screening process, scientists at Dana-Farber Cancer Institute have identified a gene that is made inappropriately in about a third of all breast cancers. The discovery, reached in collaboration with researchers at Brigham and Women's Hospital (BWH) and the Broad Institute of Harvard and MIT, is reported in the June 15, 2007 issue of the journal Cell. [click link for full ... (Wed, 20 Jun 2007 09:04:21 GMT)

Acacia Technologies Licenses Credit Card Fraud Protection Technology to Goodyear Tire
NEWPORT BEACH, Calif.----Acacia Research Corporation announced today that Financial Systems Innovation LLC, a wholly owned subsidiary of the Acacia Technologies group, a leader in technology licensing, has entered into non-exclusive licenses covering a patent that applies to credit card fraud protection technology with Goodyear Tire & Rubber Company. (Wed, 20 Jun 2007 10:00:00 GMT)

DNAPrint(R) Genomics to Present at ValueRich Small-Cap Financial Expo
DNAPrint Genomics, Inc. today announced that President and Chief Executive Officer Richard Gabriel will present an overview of the Company to investors at the ValueRich Small-Cap Financial Expo on Thursday, June 21 at 11:40 a.m. (Wed, 20 Jun 2007 11:00:00 GMT)

AlgoNomics To Raise 1.5 million Euro
GHENT, Belgium----AlgoNomics NV, the immunoprofiling company, announced today that it raised 1.5 million euro to further accelerate the development of its in vitro screening platform that expands the company's existing immunogenicity screening services and tools. (Wed, 20 Jun 2007 11:00:00 GMT)

Ingenuity Systems Chosen to be Sole Pathways Provider for Integromics in Andalusian Core Facility
Ingenuity Systems, the leading provider of information solutions for the exploration, interpretation, and analysis of experimental data for life sciences researchers, today announced that it has been awarded a new, five-year contract with Integromics, one of the foremost life science IT companies in Spain and the service provider to the Genomics, Proteomics and Bioinformatics Core Facility of ... (Wed, 20 Jun 2007 11:02:57 GMT)

Scientists Discover New Role for MicroRNAs in Stopping Tumor Cell Growth
FOSTER CITY, Calif.----Scientists at Cold Spring Harbor Laboratory , Howard Hughes Medical Institute , and Applied Biosystems , an Applera Corporation business, have discovered that a family of small RNA molecules known as microRNAs are components in a well-studied tumor suppressor network, the p53 pathway, that stops the growth of tumor cells in mice. (Wed, 20 Jun 2007 11:30:00 GMT)

Acacia Technologies Licenses Credit Card Fraud Protection Technology to Goodyear Tire
NEWPORT BEACH, Calif., (Wed, 20 Jun 2007 11:39:08 GMT)

Mercury Computer Systems and PNNL Leverage Gaming Technology to Develop Solutions for National Security, Cyberspace, ...
The same computing power used in millions of game consoles may soon help tackle computational challenges in national security, cyberspace, and bioinformatics. Mercury Computer Systems, Inc. and Pacific Northwest National Laboratory are collaborating to apply multicore technology such as Graphics Processing Units and the Cell Broadband Engine processor to these critical applications. (Wed, 20 Jun 2007 12:57:00 GMT)

New Tumour Markers 'Spot The Differences'
Pancreatic cancer has the poorest prognosis of all cancers: the survival rate after five years with the disease is less than five percent and on average, patients who have been diagnosed with it do not live longer than six months. New findings reveal some of the orders that allow pancreatic tumours to grow quickly, feed and invade other tissues. This research may help with developing new ... (Wed, 20 Jun 2007 15:06:36 GMT)

Research Triangle Park, North Carolina and St. Louis, Missouri June 20, 2007
Athenix Corp . and Monsanto Company today announced they have entered into a three-year research collaboration for insect control on a key class of insects that affects a number of Monsanto's major crops of interest. Financial terms of the agreement were not disclosed. (Wed, 20 Jun 2007 15:09:31 GMT)

Teenager to present research paper at int'l conferences
SINGAPORE: An 18-year-old will present a research paper at an international conference this month, and another one next month. (Wed, 20 Jun 2007 15:17:05 GMT)

AlgoNomics To Raise 1.5 Million Euro
AlgoNomics NV, the immunoprofiling company, announced today that it raised 1.5 million euro (about 2.0 million USD) to further accelerate the development of its in vitro screening platform that expands the company's existing immunogenicity screening services and tools. (Wed, 20 Jun 2007 15:24:48 GMT)

Ames, Iowa June 20, 2007 The Iowa State University
Department of Agronomy has named two new endowed chairs in the areas of crop genomics and biorenewable crop research. The George F. Sprague Endowed Chair will be filled by William Beavis, chief science officer at the National Center for Genome Resources. (Wed, 20 Jun 2007 18:24:28 GMT)

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