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Bioinformatics News 12/2006 (Page 5)

Protein's Tail May Be Flu Virus's Achilles Heel (Science Daily)
New research from Rice University and the University of Texas at Austin (UT) has revealed a potential new target that drug makers can use to attack several strains of influenza, including those that cause bird flu. The research, published online December 6 by Nature, offers evidence of a potential drug target in a flu protein that plays a vital role in all strains of influenza A, including Hong

Researchers Create Model Of Key Immune-system Component (Science Daily)
Researchers at Université de Montréal, working with teams at Massachusetts General Hospital and Johns Hopkins University, have made a major breakthrough in understanding an essential aspect of the immune system. For the first time, using a systems biology approach, they have developed a model that facilitates the study of the function of the phagosome. The results of their study were published

Researchers Developing Molecular Delivery Vehicles For Genetic Therapies (Science Daily)
Researchers at New York University are working to develop molecular delivery vehicles that can be used to transport nucleic acids into diverse cell types, which may lead to eventual applications in genetic therapies. Their work is described as part of the cover story in the November 13 issue of the American Chemical Society publication Chemical and Engineering News.

Solving Darwin's Dilemma: Oxygen May Be The Clue To First Appearance Of Large Animals (Science Daily)
The sudden appearance of large animal fossils more than 500 million years ago -- a problem that perplexed even Charles Darwin and is commonly known as "Darwin's Dilemma" -- may be due to a huge increase of oxygen in the world's oceans, says Queen's paleontologist Guy Narbonne, an expert in the early evolution of animals and their ecosystems.

Breast-Cancer Survival Predicted By Protein-Based Tumor Biomarker (Medical News Today)
The first and largest clinical trial of its kind confirms that a protein called p27 may be a valuable tool for predicting survival after a diagnosis of breast cancer.The findings, by lead author Peggy Porter, M.D., of Fred Hutchinson Cancer Research Center, in collaboration with colleagues from nine other institutions, appear in the Dec. 6 issue of the Journal of the National Cancer Institute.

Finding Stress Points in Apple's Business Strategy (TechNewsWorld.com)
The collective Apple community has been so intoxicated by the iPod, the success of the iTunes Store, MacBook sales, and excellent Mac OS X security that no one is reflecting on the areas where Apple is vulnerable. Perhaps it's unpleasant to think about, but neither do we want to live in a state of denial. So here are some areas where I think Apple should pay more attention.

NIAID media availability: Examining genetic variability of malaria parasite offers insight (EurekAlert!)
WHAT: Back-to-back papers published online this week in Nature Genetics reveal important new details about the genetic variability of the malaria parasite and provide new clues for how it causes disease.

Genetic map offers new tool for malaria research (EurekAlert!)
Boston, MA and Cambridge, MA, Sun. December 10, 2006 -- An international research team announced today the completion of a genome-wide map that charts the genetic variability of the human malaria parasite Plasmodium falciparum.

Dr. S.M. Faruque, Scientist and Head, Molecular Genetics Laboratory of LSD, ICDDR,B received TWAS Award in Brazil (News From Bangladesh)
TWAS, the Academy of Sciences for the Developing World, has announced its 2005 prize winners. The annual TWAS Prizes, awarded in eight fields of scientific research, rank among the highest scientific accolades given to scientists in developing countries.

Genetic Map Offers New Tool for Malaria Research (Newswise)
Scientists create genome-scale map of genetic variation for malaria parasite; initial use unlocks genes involved in drug resistance.

Banner Health OKs Valley Cancer Center: Facility to Be State's 2nd; Patients to Have Access to Clinical Trials (RedNova)
By Jill Redhage, The Tribune, Mesa, Ariz. Dec. 10--A unanimous vote Saturday morning by the 15 board members of Banner Health made plans a "go" for the creation of the Valley's first comprehensive cancer center.

Discovery of new protein may help in Alzheimer's treatments (Milwaukee Journal Sentinel)
After decades of going after a sticky substance called beta amyloid that accumulates in the brains of Alzheimer's...

Blood test in the works to detect breast cancer (The Arizona Republic)
Phoenix company is conducting a clinical trial for a blood test to detect breast cancer. The plan is to offer the test widely next year.

Three Bay Area labs bid for energy research cash (BizJournals)
Just when we finally started to understand proteomics and gene splicing, it turns out biopharma is so last year. Now, three national laboratories are hoping to use the same technologies to turn alternative energy into the Bay Area's next boom industry.

Gene Discovered by Researchers Tied to Pancreatic Cancer (Newswise)
A gene discovered by researchers at the University of North Carolina at Chapel Hill School of Medicine has been associated with two forms of pancreatic cancer, according to a study by an international group of researchers.

A Brassy Move (The Harvard Crimson)
The sound of a trumpet no longer echoes through Harvard’s Center for Systems Biology. After nearly three decades of work in science, the center’s executive director left Harvard to become a professional musician.

New Nanomechanical Method For Detecting Disease- And Treatment-Relevant Genes (Medical News Today)
Innovative technique offers new possibilities for matching drug treatments more closely to patient needsResearchers from the National Centre of Competence in Research at the newly established Swiss Nanoscience Institute (SNI) in Basel, together with Roche scientists, have developed an innovative method for the rapid and sensitive detection of disease- and treatment-relevant genes. [click link for

(AFX UK Focus) 2006-12-11 08:03 GMT: Galapagos to get up to 2.4 mln eur to work on medicines for Lou Gehrig disease (Interactive Investor)
AMSTERDAM (AFX) - Galapagos Genomics NV said it has signed a two-year agreement worth up to 2.4 mln eur with The ALS Association of the US, which has the goal of finding medicines to treat amyotrofic lateral sclerosis (ALS), better known as Lou Gehrig's disease.

Genting Consortium: Resorts World at Sentosa will boost economy (Channel NewsAsia)
SINGAPORE: The Genting International-Star Cruises Consortium, who on Friday won the bid to build the Integrated Resort at Sentosa, has said its proposed Resorts World at Sentosa will bring significant contributions to the Singapore economy.

NIH Funds Are for Research (Wired News)
Naysayers argue that embryonic stem-cell research deserves no federal funding because it has shown no success. Neither have other heavily funded research programs. By Brandon Keim.

iHorizons to develop home-grown software at Qatar Science & Technology Park (AME Info)
Qatari software company iHorizons announced today that it will establish a research and development company at Qatar Science & Technology Park.

AutoGenomics Submits 510K to the FDA For 2C9 / VKORC1 to Assess Warfarin Sensitivity (PR Newswire via Yahoo! Finance)
AutoGenomics, a leader in developing automated molecular testing solutions, announced today that it has submitted a 510K application to the FDA in October 2006 for its CYP450 2C9 / VKORC1 assay on its INFINITI System.

Research and Markets: Gain Insight into the Historical Perspective to Drug Discovery, Such as the Pioneering Work of (Business Wire via Yahoo! Finance)
DUBLIN, Ireland----Research and Markets has announced the addition of Novel Targets in Drug Discovery to their offering.

The MBAs who changed the world? (CNN.com)
When most MBA students take on practical business exercises their main ambitions are a bit of useful experience and a good grade.

Bionovo Expands Scientific Advisory Board (PR Newswire via Yahoo! Finance)
Bionovo Inc. announced today that Dr. Terry Speed will join the company's scientific advisory board.

Invitrogen Features New Scientific Online Resources at American Society for Cell Biology (ASCB) Meeting (Business Wire via Yahoo! Finance)
SAN DIEGO----Invitrogen Corporation , a leader in life science research, today introduced the newest member of its free online scientific resource collection, iGene, a platform that allows researchers to conveniently search for experimental reagents by gene or protein.

American Chemical Society's Weekly PressPac -- December 6, 2006 (EurekAlert!)
Here is the latest American Chemical Society (ACS) News Service Weekly press package (PressPac) with reports selected from 35 major peer-reviewed journals and Chemical & Engineering News.

AutoGenomics Submits 510K to the FDA For 2C9 / VKORC1 to Assess Warfarin Sensitivity (RedNova)
CARLSBAD, Calif., Dec. 11 /PRNewswire/ -- AutoGenomics, a leader in developing automated molecular testing solutions, announced today that it has submitted a 510K application to the FDA in October 2006 for its CYP450 2C9 / VKORC1 assay on its INFINITI(TM) System.

Covalys Announces CTI Project Targeting First Use of SNAP-tag in Living Mice (PR Web via Yahoo! News)
Witterswil, Switzerland (PRWeb) December 11, 2006 -- Covalys (www.

Fear of migraine destroys quality of life for men (EurekAlert!)
The unpredictability of symptoms and apprehension associated with living with migraine is limiting mens' lives, according to research from Griffith University’s Genomics Research Centre.

Mutant mouse provides insights into breast cancer (PhysOrg)
By discovering a mutant mouse that is highly susceptible to mammary tumors, Cornell researchers have found a novel potential link between genetic defects in DNA replication (copying) and breast cancer.

Invitrogen Features New Scientific Online Resources At American Society For Cell Biology (ASCB) Meeting (BioresearchOnline)
Invitrogen Corporation, a leader in life science research, today introduced the newest member of its free online scientific resource collection, iGene, a platform that allows researchers to conveniently search for experimental reagents by gene or protein

Covalys Announces CTI Project Targeting First Use of SNAP-tag in Living Mice (PR Web)
Covalys announces a joint CTI-project with the Ecole Polytechnique Fédérale de Lausanne targeting the use of ‘SNAP-tag for selective labeling of fusion proteins in living mice’. (PRWeb Dec 11, 2006) Post Comment:Trackback URL: http://www.prweb.com/chachingp

AMEX Accepts Matritech's Plan to Regain Compliance with Continued Listing Standards (Business Wire via Yahoo! Finance)
NEWTON, Mass.----Matritech , a leading marketer and developer of protein-based diagnostic products for the early detection of cancer, today announced that the American Stock Exchange has accepted the Company's plan to regain compliance with continued listing standards of AMEX.

Evolution And The Workaround: Do Aggressive Cancers Pile Up Extra Chromosomes As Genomic ... (Science Daily)
At the American Society for Cell Biology 2006 conference, scientists will describe new research indicating that both yeast and cancer cells evolve chromosome duplications to work around lethal stresses.

Research and Markets: Key Company Data Now Available on Ariadne Genomics (Business Wire via Yahoo! Finance)
DUBLIN, Ireland----Research and Markets has announced the addition of Ariadne Genomics - Company Profile to their offering.

Regents recognize outstanding service (Eastern Arizona Courier)
Wick Communications co-owner Robert Wick was honored by the Arizona Board of Regents with the 2006 Regents’ Award for Outstanding Service to Higher Education.

Bio-IT Briefs (Bio-IT World)
December 11, 2006 | Researchers at Rensselaer Polytechnic Institute will continue to advance the frontiers of computational science with the help of IBM’s Blue Gene supercomputer.

Dr. S.M. Faruque, Scientist and Head, Molecular Genetics Laboratory of LSD, ICDDR,B received TWAS Award in Brazil (News From Bangladesh)
TWAS, the Academy of Sciences for the Developing World, has announced its 2005 prize winners. The annual TWAS Prizes, awarded in eight fields of scientific research, rank among the highest scientific accolades given to scientists in developing countries.

Dr. Hans-Joachim Bohm Named President of Roche Palo Alto (PR Newswire via Yahoo! Finance)
Roche has announced that Hans-Joachim Bohm, Ph.D., has been appointed president of Roche Palo Alto LLC. As president, Dr. Bohm is responsible for managing a research site focused on early discovery in three of Roche's therapy areas: Virology, Neurosciences and Autoimmunity, Inflammation and Transplantation.

Genomics dealing with great expectations (Gazette.Net)
That whole human genome thing may have been a big misunderstanding. In the six-plus years since researchers completed mapping the human genome to much fanfare, many high-profile companies based on the science have yet to show a profit.

Pioneers in field of functional genomics work toward gene therapy for vision defects (EurekAlert!)
"Primates and humans have three photoreceptors and can only see four basic colors, red, green, blue and yellow," says Jay Neitz, Ph.D. "Birds, fish and reptiles have four photoreceptors, allowing them to see things we cannot.

Columbia University licenses next-generation DNA sequencing technology (EurekAlert!)
Columbia University announces today that it recently executed an exclusive license agreement for a next generation DNA sequencing technology to Intelligent Bio-Systems (IBS), Inc. This innovative DNA-sequencing technology was invented by Dr. Jingyue Ju, professor of Chemical Engineering and head of DNA Sequencing and Chemical Biology at the Judith P. Sulzberger, M.D. Columbia Genome Center at

Pioneers in Field of Functional Genomics Work Toward Gene Therapy for Vision Defects (Newswise)
For millennia anglers have wondered how fish see colors, and the rainbow of lures in every bait shop reveal that we're still guessing. But, in fish, reptiles and birds, that's all we can do for now, according to husband and wife vision researchers, Drs. Jay and Maureen Neitz at the Medical College of Wisconsin in Milwaukee.

A Cryptologist Takes a Crack at Deciphering DNA?s Deep Secrets (New York Times)
Nick Patterson, a self-professed ?data-guy,? explores the link between humans and chimpanzees.

Protein Biomarker "Fingerprint" in Spinal Fluid Could Spot Alzheimer's Disease (Newswise)
Today, physicians must rely on their clinical judgment to decide whether a patient has Alzheimer's rather than some other form of dementia. In many cases, the diagnosis remains uncertain until autopsy. Now scientists have identified a neurochemical "fingerprint" which may someday be used to identify patients living with Alzheimer's disease.

Protein 'fingerprint' in spinal fluid could spot Alzheimer's disease (EurekAlert!)
ITHACA, N.Y. — Scientists collaborating at Cornell University in Ithaca and Weill Cornell Medical College in New York City have identified a panel of 23 protein biomarkers in cerebrospinal fluid that acts as a neurochemical "fingerprint," which doctors might use someday to identify patients living with Alzheimer's disease.

Spinal fluid may hold key to Alzheimer's (MSNBC)
Scientists appear to have found a fingerprint of Alzheimer’s disease lurking in patients’ spinal fluid, a step toward a long-awaited test for the memory-robbing disease that today can be diagnosed definitively only at autopsy.

Protein 'Fingerprint' in Spinal Fluid Could Spot Alzheimer's Disease (Newswise)
Scientists collaborating at Cornell University in Ithaca and Weill Cornell Medical College in New York City have identified a panel of 23 protein biomarkers in cerebrospinal fluid that acts as a neurochemical "fingerprint," which doctors might use someday to identify patients living with Alzheimer's disease. The research will be published in the December online-edition of the journal Annals of

Software firm plans technology park (Gulf Times)
Qatari software company iHorizons will establish a research and development company at Qatar Science and Technology Park (QSTP), it was announced yesterday.


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