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Bioinformatics News 11/2006 (Page 4)

Nature's nanomachines harnessed to make drugs (PhysOrg)
Many bacteria produce toxins that can threaten human health, however new research into how bacteria secrete these substances is giving clues as to how scientists could harness these processes to produce biopharmaceuticals. Researchers at the John Innes Centre (JIC) in Norwich have used state-of-the-art technology to study a nanomachine in soil bacteria called the Tat system, which the bacteria

Tumor Suppressor Gene Protects Against Pre-cancerous Development (Science Daily)
Cell biologists have provided further evidence that a gene thought to play a role in suppressing tumors actually protects against the development of pre-cancerous cell growth as well. The researchers say that the gene, caveolin-1, which they found in two major types of breast cells, could be a potential target for future drugs aimed at preventing breast cancer. The work also suggests a

Matritech, Inverness partner on OTC bladder cancer test (BizJournals)
Two Bay State biotechnology firms have teamed to bring a urine test for bladder cancer to the over-the-counter market.

QuantRx(R) Biomedical to Participate in MEDICA, International Medical Trade Fair, in Duesseldorf, Germany (RedNova)
QuantRx(R) Biomedical Corporation (OTCBB: QTXB)

Pet-friendly donations (Herald Democrat)
With Thanksgiving just around the corner, I can’t help but feel grateful for the good health of family, friends and the pets of my world. The past year, I’ve written about a variety of subjects, but none garnered as much response as Darcy’s story and helping pets through their own grief.

QuantRx(R) Biomedical to Participate in MEDICA, International Medical Trade Fair, in Düsseldorf, Germany (SYS-CON Media)
QuantRx® Biomedical Corporation (OTCBB: QTXB), an emerging leader in the research and development of medicaldiagnostic platforms and products, today announced that the company willparticipate in MEDICA 2006, the world's leading medical trade fair, to beheld November 15-18, 2006, at the Düsseldorf Trade Fair Centre in Germany.

NCI Scientists Launch Spotlight on Molecular Profiling (National Cancer Institute)
Researchers at the National Cancer Institute (NCI), part of the National Institutes of Health (NIH), and their colleagues today introduced a new series of research articles, "Spotlight on Molecular Profiling," in the November 7, 2006, issue of Molecular Cancer Therapeutics *. The series will highlight molecular profiling studies that provide broad-spectrum genomic and proteomic data that could

The Prairie Star (Prairie Star)
It's not your dad's corn hybrid anymore. Despite hot and dry conditions this summer, corn yields across the U.S. in 2006 will average 153.5 bushels/acre. Those high yields are due, in part, to superior genetics.

Why The Flu Makes Some People Sicker Than Others - Identifying Key Genes Could Help Identify Those Most At Risk (Medical News Today)
With lessons from the 1918 flu pandemic in the rearview mirror and the avian flu a looming obstacle in the road ahead, researchers from Southern Illinois University School of Medicine are trying to understand why a flu virus kills some people but not others. [click link for full article]

Anti-Inflammatory Drug Reduces Nerve Death in Mouse Model of Parkinson's Disease (Newswise)
Using a mouse model of Parkinson's disease, scientists at the Buck Institute have shown for the first time that neurons associated with PD die due to inflammation. The study also shows that treatment with anti-inflammatory drug minocycline, reduced neuronal death in these mice.

GenoLogics Closes Additional Financing (CanadaIT.com)
Vancouver, BC, November 6, 2006--(T-Net)--GenoLogics Life Sciences Software, a leading developer of lab and scientific data management solutions, today announced it has completed a second round of financing led by OVP Venture Partners in Seattle , along with Growth Works and Yaletown Venture Partners.

Neuron Cell Stickiness May Hold Key To Evolution Of The Human Brain (Medical News Today)
The stickiness of human neurons may have been a key factor in why the human brain evolved beyond the brains of our primate relatives. In a study comparing the genomes of humans, chimpanzees, mice and other vertebrates, researchers at the U.S. [click link for full article]

Agendia's MammaPrint(R) Micro-Array Test Confirmed to Be a Reliable Diagnostic Tool for Breast Cancer (Market Wire via Yahoo! Finance)
In a publication entitled 'Converting a breast cancer microarray signature into a high-throughput diagnostic test' in the international journal BMC Genomics, made available online on October 31 2006, it is shown that micro-array technology can be a reliable tool for use in a clinical diagnostic setting.

Agendia's MammaPrint(R) Micro-Array Test Confirmed to Be a Reliable Diagnostic Tool for Breast Cancer (RedNova)
In a publication entitled 'Converting a breast

NCI Scientists Launch Spotlight on Molecular Profiling (Kansas City InfoZine)
'This emphasis on molecular profiling reflects a shift in research from small-scale to large-scale efforts..."

Illumina Genotyping Technology Selected by Erasmus MC for Europe's Largest Cohort Study (Business Wire via Yahoo! Finance)
SAN DIEGO----Illumina, Inc. announced today that Erasmus MC, University Medical Centre in Rotterdam, the Netherlands' largest and most multi-faceted academic medical facility has purchased two fully automated BeadStations that will use the Infinium HumanHap550 BeadChip to genotype more than 10,000 samples.

DNAPrint Genomics EuroDNA(TM) Test Used as Basis for Reality Show on British Television (Market Wire via Yahoo! Finance)
DNAPrint Genomics, Inc. today announced that the Company's EuroDNA(TM) product has been employed as an integral part of the British television reality program, "100% English," and that a recent episode of the program has prompted speculation that Dame Margaret Thatcher, Baroness of Kesteven and former Prime Minister of Great Britain, may have Middle Eastern DNA, according to an Oct. 29 article

Agendia's MammaPrint(R) Micro-Array Test Confirmed to Be a Reliable Diagnostic Tool for Breast Cancer (SYS-CON Media)
In a publication entitled'Converting a breast cancer microarray signature into a high-throughputdiagnostic test' in the international journal BMC Genomics, made availableonline on October 31 2006, it is shown that micro-array technology can be areliable tool for use in a clinical diagnostic setting.

Lumera Reports Third Quarter 2006 Results and Progress in Product Development (Business Wire via Yahoo! Finance)
BOTHELL, Wash.----Lumera Corporation , a leader in the emerging field of nanotechnology, today reported financial results for the third quarter of 2006 and released information regarding its current product development progress.

Health and Meat Animal Production (Agricultural Research Magazine)
An ounce of prevention is worth a pound of cure—particularly when it comes to medicine. This maxim is at the heart of many Agricultural Research Service (ARS) animal health programs, which aim to prevent illness whenever possible and treat it quickly when it does arise.

Agendia's MammaPrint(R) Micro-Array Test Confirmed to Be a Reliable Diagnostic Tool for Breast Cancer (SYS-CON Media)
In a publication entitled'Converting a breast cancer microarray signature into a high-throughputdiagnostic test' in the international journal BMC Genomics, made availableonline on October 31 2006, it is shown that micro-array technology can be areliable tool for use in a clinical diagnostic setting.

Affymetrix to Webcast Presentations at Two November Financial Conferences (Business Wire via Yahoo! Finance)
SANTA CLARA, Calif.----Affymetrix, Inc. today announced that company management will provide an overview of Affymetrix and outline future growth opportunities at two upcoming financial conferences.

The genomics revolution (OECD Observer)
What do worms, fruit flies and people have in common? In fact, humans have a great deal in common genetically with other organisms, even "primitive" ones. Apart from that, they share the distinction of being among the first DNA blueprints to have been mapped and published.

Pet-friendly donations (Herald Democrat)
With Thanksgiving just around the corner, I can’t help but feel grateful for the good health of family, friends and the pets of my world. The past year, I’ve written about a variety of subjects, but none garnered as much response as Darcy’s story and helping pets through their own grief.

DNAPrint Genomics EuroDNA(TM) Test Used as Basis for Reality Show on British Television (SYS-CON Media)
DNAPrint Genomics, Inc. (OTCBB: DNAG) todayannounced that the Company's EuroDNA(TM) product has been employed as anintegral part of the British television reality program, '100% English,'and that a recent episode of the program has prompted speculation that DameMargaret Thatcher, Baroness of Kesteven and former Prime Minister of GreatBritain, may have Middle Eastern DNA, according to an Oct. 29

Alcohol Bad For Lungs As Well As Liver (Medical News Today)
Chronic alcohol abuse disrupts the proteins that keep fluids out of the lung, lowers a protective antioxidant, disrupts immune defenses and can lead to a condition known as 'alcoholic lung,' according to research to be presented at the conference, "Physiological Genomics and Proteomics of Lung Disease. [click link for full article]

Vaccine-producing 'Plant-factories' (Science Daily)
A research team has discovered a new route for the transport of proteins in plant cells, a discovery that will enable the biotechnological design of plant factories.

Applied Genomics gets boost (The Huntsville Times)
The biotech industry is developing rapidly and the Huntsville Angel Network expects biotech companies to gain momentum during the next few years.

'Muscle' protein drives prostate cancer (EurekAlert!)
Researchers at the Johns Hopkins Kimmel Cancer Center have for the first time implicated the muscle protein myosin VI in the development of prostate cancer and its spread.

NIDDK's Genomics Lab to Offer Microarray Services to All of NIH (GenomeWeb News)
GenomeWeb Daily News You are not logged in. Existing subscribers login here . New to GenomeWeb? Register quickly here for your free subscription.

The Prairie Star (Prairie Star)
It's not your dad's corn hybrid anymore. Despite hot and dry conditions this summer, corn yields across the U.S. in 2006 will average 153.5 bushels/acre. Those high yields are due, in part, to superior genetics.

Why A Flu Virus Kills Some People But Not Others (Medical News Today)
With lessons from the 1918 flu pandemic in the rearview mirror and the avian flu a looming obstacle in the road ahead, researchers from Southern Illinois University School of Medicine are trying to understand why a flu virus kills some people but not others. [click link for full article]

S&P: Fear Not for Big Pharma (BusinessWeek)
Democrats' electoral gains may pressure drug stocks, but S&P thinks investor worries are overblown and keeps a positive outlook on the sector

India established 35 research networks in 3 years:ICAR (New Kerala)
New Delhi, Nov 8: India has established nearly 35 strategic research networks during the last three years in areas such as genomics, gene pyramiding, molecular breeding and integrated disease management, said a top official of Indian Council of Agricultural Research.

Muscle protein linked to prostate cancer spread (New Kerala)
Washington, Nov 9: Researchers at the Johns Hopkins Kimmel Cancer Centre have found a potential link between the muscle protein myosin VI and prostate cancer.

Business briefs (The Herald-Tribune)
SARASOTA

Stellar Pharmaceuticals Announces 2006 Third Quarter Financial Results (Market Wire via Yahoo! Finance)
Stellar Pharmaceuticals Inc.(OTC.BB: SLXCF), a Canadian pharmaceutical developer and marketer of high quality, cost-effective products for select health care markets, today announced financial results for the third quarter ended September 30, 2006.

Software aids in protein identification and quantitation. (ThomasNet)
Featuring PepQuan capabilities, BioWorks(TM) v3.3 allows automated quantitative analysis of iTRAQ(TM), SILAC(TM), and ICAT® labeled samples, as well as label-free quantitation techniques. SEQUEST® protein search algorithm identifies proteins by comparing experimental tandem mass spectrometry data with standard protein and DNA databases. Software features pre- and post- search filters that remove

GC/MS System detects low levels of dioxins and furans. (ThomasNet)
Helping governmental, industrial, and commercial laboratories meet strict US EPA and EU directives, DFS High Resolution GC/MS System performs precise confirmation analyses of dioxins and furans in low femtogram range. Two Trace GC Ultras(TM) and TriPlus(TM) Autosampler achieve low LOQs, enabling rapid sample preparation. System features Multiple Ion Detection, which allows scan-to-scan monitoring

Matritech Promotes Bladder Cancer Awareness November 12-18 and Encourages People at Risk for the Cancer to be Tested (Business Wire via Yahoo! Finance)
NEWTON, Mass.----Matritech, Inc. a leading developer of protein-based diagnostic products for the early detection of cancer has joined forces for the second consecutive year with leading urologists, urology nurses, community based healthcare providers, bladder cancer patient advocates, and firefighters to raise awareness of bladder cancer during National Bladder Health Awareness Week, November

Research targets viruses (UB Reporter)
Researchers at CUBRC and UB's New York State Center of Excellence in Bioinformatics and Life Sciences are developing radically new drugs designed to cure viruses ranging from the deadly Ebola virus to the common cold, thanks to a major $8.2 million grant from the U.S. Department of Defense.

Selecting life: Scientists find new way to search for origin of life (EurekAlert!)
Washington, D.C. -- Over the last half century, researchers have found that mineral surfaces may have played critical roles organizing, or activating, molecules that would become essential ingredients to all life--such as amino acids (the building blocks of proteins) and nucleic acids (the essence of DNA). But which of the countless possible combinations of biomolecules and mineral surfaces were

DNA microarrays in IVD applications (Medical Device Link)
Molecular diagnostics is an emerging segment of the IVD market that is growing rapidly and garnering attention due to its potential to revolutionize disease management.

Matritech Promotes Bladder Cancer Awareness November 12-18 and Encourages People at Risk for the Cancer to Be Tested (RedNova)
Matritech, Inc. (Amex: MZT) a leading developer

Pharmaceutical, Healthcare & Life Sciences (Mondaq)
The world is witnessing the big bang of scientific discovery in the medical device sector.

Starbridge and Impulse Collaborate on C-to-FPGA Acceleration (Business Wire via Yahoo! Finance)
KIRKLAND, Wash. & SALT LAKE CITY----Starbridge Systems and Impulse Accelerated Technologies today announced a joint initiative to provided graphical and C-language tools for high-performance, FPGA-based computing.

Selecting life: Scientists find new way to search for origin of life (PhysOrg)
Over the last half century, researchers have found that mineral surfaces may have played critical roles organizing, or activating, molecules that would become essential ingredients to all life--such as amino acids (the building blocks of proteins) and nucleic acids (the essence of DNA). But which of the countless possible combinations of biomolecules and mineral surfaces were key to this

Illumina to Present at the Lehman Brothers Third Annual Small Cap Conference (Business Wire via Yahoo! Finance)
SAN DIEGO----Illumina, Inc. announced today that Jay Flatley, President and Chief Executive Officer, will present an overview of the Company's commercial and product development activity at the upcoming Lehman Brothers Small Cap Conference in Dana Point, California.

Decoded Sea Urchin Genome Shows Surprising Relationship To Humans (Science Daily)
The Sea Urchin Genome Sequencing Project consortium, led by the Human Genome Sequencing Center at Baylor College of Medicine in Houston, announced today the decoding and analysis of the genome sequence of the sea urchin, Strongylocentrotus purpuratus.

RNA Map Provides First Comprehensive Understanding of Alternative Splicing (Newswise)
A new RNA map shows for the first time how the specific location of short snippets of RNA affects the way that alternative splicing is controlled in the brain.


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