Previous 1 2 3 4 5 Next
DNA analysis could boost accuracy of thyroid tests
By fine-tuning "fine-needle aspiration" biopsies with a super-fast genetic microarray technology, a team of surgeons from NewYork-Presbyterian Hospital/Weill Cornell Medical Center in New York City says they can greatly enhance the accuracy of these tests. (Tue, 14 Nov 2006 18:07:29 GMT)
Jordanian scientists in Bridging the Rift project come to Cornell for training in analyzing biological data
A group of 15 prominent Jordanian scientists visited Cornell Nov. 2 to begin work on a long-term project to study life forms that live in extreme conditions. (Tue, 14 Nov 2006 19:03:39 GMT)
Study reveals 'signature of heart failure'
Tell-tale pattern of RNA expression could lead hunt for better treatments. (Tue, 14 Nov 2006 19:52:23 GMT)
Spot-Swap Among The World's Fastest Supercomputers
The Top 500 list of the world's most powerful shows some shakeup -- after No. 1 BlueGene/L. (Tue, 14 Nov 2006 19:58:33 GMT)
Johns Hopkins Proteomics Center to Use Ludesi's Gel-Imaging Software
GenomeWeb Daily News You are not logged in. Existing subscribers login here . New to GenomeWeb? Register quickly here for your free subscription. (Tue, 14 Nov 2006 20:02:03 GMT)
ServerWatch > News
The End of the Proprietary Era Businesses are moving away from proprietary architectures to reduce their TCO and improve performance, scalability, and availability. (Tue, 14 Nov 2006 20:43:44 GMT)
RNA Map Provides First Comprehensive Understanding Of Alternative Splicing
It's biology's version of the director's cut. In much the same way that numerous films could be stitched together from a single reel of raw footage, a molecular process called alternative splicing enables a single gene to produce multiple proteins. [click link for full article] (Tue, 14 Nov 2006 21:08:06 GMT)
Taking "Chips" to the Next Level of Gene Hunting
Researchers at the Johns Hopkins' High Throughput Biology Center have invented two new gene "chip" technologies that can be used to help identify otherwise elusive disease-causing mutations in the 97 percent of the genome long believed to be "junk." (Tue, 14 Nov 2006 22:17:29 GMT)
DNA Analysis Could Boost Accuracy of Thyroid Tests
By fine-tuning "fine-needle aspiration" biopsies with a super-fast genetic microarray technology, a team of surgeons from NewYork-Presbyterian Hospital/Weill Cornell Medical Center in New York City says they can greatly enhance the accuracy of these tests. (Tue, 14 Nov 2006 22:29:49 GMT)
New Technology Expected To Help Rapidly Identify Avian Flu Strains
Scientists from the University of Colorado at Boulder and the Centers for Disease Control and Prevention in Atlanta have developed a novel "gene chip" based on a single influenza virus gene that is expected to allow scientists to quickly identify specific flu viruses, including avian influenza H5N1. (Tue, 14 Nov 2006 22:39:32 GMT)
Sun Bulks Up HPC Offerings
At the Supercomputing 2006 show, the OEM rolls out a host of hardware, software and services aimed at the high-performance computing space. (Tue, 14 Nov 2006 23:24:29 GMT)
Free article by Nobel laureate available
The U.S. journal Molecular and Cellular Proteomics has made an article published by Nobel Laureate Andrew Fire available free to the public. (Tue, 14 Nov 2006 23:24:46 GMT)
Panasas Launches New ActiveStor Storage Cluster Solutions
Panasas announced the third generation of the company's operating environment, ActiveScale 3.0. The ActiveScale 3.0 operating environment adds several new features to the established PanFS parallel file system that Panasas has deployed in top companies and scientific organizations around the world. (Wed, 15 Nov 2006 00:00:49 GMT)
Stanford Gets $20M Cancer-Stem Cell Site
Stanford University has received a $20 million grant to establish a new research center specializing in cancer-stem cell research. The cells are believed to be at the heart of most cancers, and learning to destroy them could yield potential cancer treatments, the university said Tuesday. (Wed, 15 Nov 2006 00:18:55 GMT)
Johns Hopkins Bayview Proteomics Center chooses Ludesi
(Full text of statement. Contact details below.) (Wed, 15 Nov 2006 03:26:49 GMT)
Bio-Rad acquires Ciphergen's ProteinChip systems business
Bio-Rad Laboratories, Inc. a multinational manufacturer and distributor of life science research and clinical diagnostics products, has completed the purchase of Ciphergen Biosystems, Inc.'s ProteinChip Systems business and worldwide technology rights to its Surface Enhanced Laser Desorption/Ionization (SELDI) for approximately $20 million in cash. (Wed, 15 Nov 2006 03:52:27 GMT)
Talent leads dancer in all directions
Twenty-year-old Kyan Unstad has been dancing nearly her whole life. (Wed, 15 Nov 2006 05:30:27 GMT)
Herzenberg accepts Kyoto Prize
The Inamori Foundation presented its 22nd annual Kyoto Prize in Advanced Technology on Nov. 10 to Leonard Herzenberg, PhD, professor of genetics, emeritus (active). (Wed, 15 Nov 2006 07:05:24 GMT)
Ludwig Fund gives $20 million for cancer research
The medical school has received a $20 million gift to establish a world-class research enterprise to study cancer stem cells, which are believed to be at the heart of most cancers. (Wed, 15 Nov 2006 07:06:47 GMT)
Illumina Technology Selected by Johns Hopkins University School of Medicine for Major Public Health Study
SAN DIEGO----Illumina, Inc. announced today an agreement with the Johns Hopkins University School of Medicine, in collaboration with researchers at the National Human Genome Center at Howard University, to utilize the Infinium® HumanHap650Y BeadChip for an asthma study of over 2,000 individuals and their families. (Wed, 15 Nov 2006 11:00:00 GMT)
Gene Silencing Technology Is Quietly Moving Toward The Clinic
The gene silencing technology showcased in the 2006 Nobel Prize in Physiology or Medicine is on an amazingly fast track toward use in treating a variety of serious diseases, according to an article scheduled for the Nov. 13 issue of the ACS's weekly newsmagazine, Chemical & Engineering News. (Wed, 15 Nov 2006 11:11:45 GMT)
Gene Machine: Cells Engineered To Prevent Sepsis Win Synthetic Biology Competition
A team of eight undergraduates from the University of Ljubljana in Slovenia won the grand prize earlier this Month at the international Genetically Engineered Machine (iGEM) competition at MIT. The group explored a way to use engineered cells to intercept the body's excessive response to infection, which can lead to a fatal condition called sepsis. (Wed, 15 Nov 2006 11:11:57 GMT)
Newly Discovered Proteins Associated With Cystic Fibrosis
Researchers have found a highly unusual distribution of proteins in the lungs and airways of people with cystic fibrosis. The discovery is preliminary, but intriguing: Finding out more about the proteins could help sort out the immune system's role in the disease. The study will be presented at a meeting of the American Physiological Society, "Physiological Genomics and Proteomics of Lung (Wed, 15 Nov 2006 11:13:08 GMT)
New Insights on Metastasis Formation in Colon Cancer
The prognosis for colon cancer depends on whether the tumor develops metastases. (Wed, 15 Nov 2006 11:35:49 GMT)
Pathbreaking Research Initiatives in the Nanobiotechnology Field
DUBLIN, Ireland----Research and Markets has announced the addition of "NanoBioTechnology: Trends and Technological Developments" to their offering. (Wed, 15 Nov 2006 13:20:00 GMT)
Los Alamos National Laboratory Completes Successful Analysis of Antibodies Using Lumera Corporation Technology
BOTHELL, Wash.----Lumera Corporation , an emerging leader in the field of nanotechnology, announced today that its proprietary Heterodimer Protein Technology and ProteomicProcessor were both successfully used to analyze single chain antibodies from Los Alamos National Laboratory . (Wed, 15 Nov 2006 13:45:00 GMT)
Purdue University Explores SGI RASC Technology to Lower Costs in Scientific Production Environments
SUPERCOMPUTING 2006, Booth #905 -- How do you run more code for more users and lower your electric bill at the same time? How do you economically serve science gateways with tens of thousands or perhaps a hundred thousand users? (Wed, 15 Nov 2006 14:00:00 GMT)
DNA Print Genomics Recommends Several Federal Sources For Funding of DNA "Cold Case" Tests
DNAPrint Genomics, Inc. today announced that, in order to encourage the use of DNA testing in the solving of so-called "cold cases," the National Institute of Justice has awarded grants to 38 police agencies across the U.S., enabling these agencies to petition the NIJ through the Grant Adjustment Notice to include DNAWitness(TM) and other DNAPrint products and services in their efforts. (Wed, 15 Nov 2006 15:01:00 GMT)
Lungs Try To Repair Damaged Elastic Fibers
The lungs of patients suffering chronic obstructive pulmonary disease (COPD) attempt to repair damaged elastic fibers, a new finding that contradicts the conventional wisdom on the capabilities of the adult lung. The researchers found that synthesis of elastin, a gene linked to elastic fiber growth, is increased in the moderately diseased tissue of COPD patients. Elastic fibers allow the lung to (Wed, 15 Nov 2006 15:11:12 GMT)
Los Alamos National Laboratory Completes Successful Analysis of Antibodies Using Lumera Corporation Technology
Lumera Corporation (Nasdaq:LMRA), an emerging l (Wed, 15 Nov 2006 15:13:58 GMT)
In Brief
As successive file formats are superceded and become obsolete, there is a danger that information held in such older formats may become difficult or impossible to retrieve – resulting in the loss of vast amounts of unique and valuable information. (Wed, 15 Nov 2006 15:21:50 GMT)
Sun Bulks Up HPC Offerings
Sun Microsystems is lengthening its list of high-performance computer offerings with new hardware, software and services designed to let users quickly deploy the necessary technologies to build compute-intensive environments. (Wed, 15 Nov 2006 16:26:11 GMT)
Solving the Riddle of Crystalline Life Patterns
Over the last half century, researchers have found that mineral surfaces may have played critical roles organizing, or activating, molecules that would become essential ingredients to all life, such as amino acids (the building blocks of proteins) and nucleic acids (the essence of DNA). (Wed, 15 Nov 2006 18:10:42 GMT)
Scientists mapping Neanderthal genome from long-ignored bone
A bone fragment that scientists had initially ignored has begun to yield secrets of the Neanderthal genome, launching a new way to learn about the stocky and muscular relative of modern humans, scientists say. Genetic material from the bone will let researchers identify most of the genome in the next two years. (Wed, 15 Nov 2006 18:11:36 GMT)
DNA Print Genomics Recommends Several Federal Sources For Funding of DNA "Cold Case" Tests
DNAPrint Genomics, Inc. (OTCBB: DNAG) today ann (Wed, 15 Nov 2006 18:18:50 GMT)
Mobious Genomics Launches ExtendaSeq(TM) SBS Chemistry Plug-in: Application Will Increase Read Lengths by a Factor of
Mobious Genomics, in association with Mobious Biosystems, is pleased to announce the availability of its ExtendaSeq chemistry plug-in for next generation Sequencing-by-Synthesis chemistry platforms. (Wed, 15 Nov 2006 18:19:00 GMT)
Neanderthal bone gives DNA clues
NEW YORK (AP) -- A bone fragment that scientists had initially ignored has begun to yield secrets of the Neanderthal genome, launching a new way to learn about the stocky and muscular relative of modern humans, scientists say. (Wed, 15 Nov 2006 18:42:16 GMT)
Purdue University Explores SGI RASC Technology to Lower Costs in Scientific Production Environments
How do you run more code for more users and lower your electric bill at the same time? How do you economically serve science gateways with tens of thousands or perhaps a hundred thousand users? Purdue University seeks to answer those questions using recently purchased SGI high performance compute and storage technology from the SGI(R) Scientific Workflow Solutions portfolio. (Wed, 15 Nov 2006 18:57:10 GMT)
Neanderthal DNA Shows No Interbreeding With Humans
WEDNESDAY, Nov. 15 (HealthDay News) -- Cutting-edge analysis of Neanderthal bone DNA indicates that the now-extinct species shared a common ancestor with modern humans, but that the two groups parted ways about 370,000 years ago and did not interbreed. (Wed, 15 Nov 2006 19:04:40 GMT)
DNA Print Genomics Recommends Several Federal Sources For Funding of DNA "Cold Case" Tests
DNAPrint Genomics, Inc. (OTCBB: DNAG) todayannounced that, in order to encourage the use of DNA testing in the solvingof so-called 'cold cases,' the National Institute of Justice (NIJ) hasawarded grants to 38 police agencies across the U.S., enabling theseagencies to petition the NIJ through the Grant Adjustment Notice (GAN) toinclude DNAWitness(TM) and other DNAPrint products and services in (Wed, 15 Nov 2006 19:58:11 GMT)
'Gene chip' test could speed H5N1 diagnosis
Nov 15, 2006 (CIDRAP News) – Scientists say they have developed an inexpensive "gene chip" test that can quickly identify a variety of influenza A viruses, including H5N1, and is less apt to be confused by viral mutations than other tests are. (Wed, 15 Nov 2006 20:36:03 GMT)
Wild chicken genome soon to be published
CAMBRIDGE, England, Nov. 15 (UPI) -- European scientists say they expect the soon to be published draft genome sequence of the wild chicken to provide insights into the human genome. (Wed, 15 Nov 2006 20:46:08 GMT)
Accelrys to Release SciTegic Pipeline Pilot(TM) 6.0, the Scientific Operating Platform for Discovery and Development
SAN DIEGO----Accelrys, Inc. , a leading provider of scientific software and services, today announced the sixth generation of SciTegic Pipeline Pilot, a platform for scientific discovery and development. (Wed, 15 Nov 2006 21:15:00 GMT)
UPI NewsTrack Health and Science News
NEW YORK, Nov. 15 (UPI) -- A U.S.-led team of biologists has captured one of the last members of a species that is the world's most endangered big cat: a Far Eastern leopard. (Wed, 15 Nov 2006 23:00:18 GMT)
Scientists mapping Neanderthal genome
A bone fragment that scientists had initially ignored has begun to yield secrets of the Neanderthal genome, launching a new way to learn about the stocky and muscular relative of modern humans, scientists say. (Thu, 16 Nov 2006 00:28:15 GMT)
Inexpensive Test Detects H5N1 Infections Quickly, Accurately
Scientists from the University of Colorado-Boulder and the U.S. Centers for Disease Control and Prevention announce development of an inexpensive “gene chip” test based on a single influenza virus gene that could let scientists quickly identify flu viruses, including H5N1 avian influenza. The advance is announced as the total number of human cases of H5N1 bird flu rises to 258, with the (Thu, 16 Nov 2006 01:39:23 GMT)
Test of Insomnia Drug Bolsters Vanda's Plan
A few years ago, drug giant Bristol-Myers Squibb Co. announced it was retooling its strategy, meaning a drug it was developing for insomnia was probably headed for the sidelines. Vanda Pharmaceuticals Inc. pounced. (Thu, 16 Nov 2006 05:58:36 GMT)
New Study Segments the Life Science Market by Media Engagement Level
BioInformatics, LLC announced today the availability of a new report "Marketing to Life Scientists 2006: Capitalizing on Media Engagement." As a basis for the report, 1300 scientists worldwide were surveyed to determine their media preferences and preferred suppliers. (PRWeb Nov 16, 2006) Trackback URI: http://www.prweb.com/zingpr.php/SW5zZS1GYWx1LUVtcHQtSGFsZi1NYWduLVplcm8= (Thu, 16 Nov 2006 08:24:27 GMT)
The Genome Institute of Singapore, in Partnership with a Top-Ten Pharmaceutical Company, Selects Illumina's HumanRef-8
SAN DIEGO----Illumina, Inc. announced today that in collaboration with a prominent pharmaceutical company, the Genome Institute of Singapore will utilize the HumanRef-8 Expression BeadChip to analyze up to 3,000 samples. (Thu, 16 Nov 2006 11:00:00 GMT)
First Light Shed On Gene Repair By Nanoscale Microscope
Proteins called H2AX act as "first aid" to DNA, among other roles. For the first time, scientists using the world's most powerful light microscope (the only one of its kind in the Americas) have seen how H2AX is distributed in the cell nucleus: in clusters, directing the first aid/repair after DNA injuries to the region where it is really needed. [click link for full article] (Thu, 16 Nov 2006 11:07:55 GMT)
Scientists mapping genetic blueprint of Neanderthals
Scientists probing a 38,000-year-old bone fragment may be within two years of deciphering the genetic blueprint of Neanderthals, humanity's prehistoric cousins, according to two studies out Wednesday. (Thu, 16 Nov 2006 11:53:13 GMT)
New Study Segments the Life Science Market by Media Engagement Level
Arlington, VA (PRWEB) November 16, 2006 -- BioInformatics, LLC announced today the availability of a new report "Marketing to Life Scientists 2006: (Thu, 16 Nov 2006 12:00:00 GMT)
Orion Genomics Announces Notice of Allowance for U.S. Patent Covering Genome Wide Novel Biomarker Discovery Platform,
Orion Genomics announced today that it has received a Notice of Allowance from the U.S. Patent and Trademark Office for a key patent application that covers Orion's MethylScope technology, a broad approach to discovering and quantifying the DNA methylation status on each and every gene in the human genome. (Thu, 16 Nov 2006 13:00:00 GMT)
Life Sciences Organizations Drive Innovation with GraphLogic Technology
BRANFORD, Conn.----GraphLogic, Inc. announced today that 454 Life Sciences, Sequenom, The Virginia Bioinformatics Institute, and Clinical Data are the most recent life sciences companies to license GraphLogic technology to streamline their scientific operations. (Thu, 16 Nov 2006 13:00:00 GMT)
Enzo Named Senior Party in Interference for Patent on Basic DNA Gel Sequencing Technology
NEW YORK----Enzo Biochem, Inc. announced today that the United States Patent and Trademark Office has declared a patent interference between an allowed patent application of its subsidiary, Enzo Life Sciences, Inc., and a patent held by California Institute of Technology and licensed exclusively to Applied Biosystems, Inc., a division of Applera Corporation . (Thu, 16 Nov 2006 13:18:00 GMT)
Helicos BioSciences Hosts Initial Thought Leadership Bioinformatics Forum
CAMBRIDGE, Mass.----Helicos BioSciences, pioneering new frontiers in genetic analysis, has announced the first of multiple symposiums uniting renowned thought leaders in the field of genomics for a discussion on operational workflow and bioinformatics tools. (Thu, 16 Nov 2006 13:30:00 GMT)
New Study Segments the Life Science Market by Media Engagement Level
BioInformatics, LLC announced today the availability of a new report "Marketing to Life Scientists 2006: Capitalizing on Media Engagement." As a basis for the report, 1300 scientists worldwide were surveyed to determine their media preferences and preferred suppliers. (Thu, 16 Nov 2006 14:00:00 GMT)
Director of biotechnology for RCCC explains what the science is
CONCORD — With all the discussion about David Murdock 's goal of a world-class biotechnology research center in Kannapolis, it's helpful to remember what biotechnology is. (Thu, 16 Nov 2006 15:03:41 GMT)
Mass Spectrometry in Biomarker Research to Exceed $745 Million by 2010
In the rapidly advancing world of biotechnology instrumentation, mass spectrometry has shown the necessary abilities to rapidly identify a variety of biochemicals, making it a workhorse for discovering and validating biomarkers in clinical research related to drug development and diagnostic applications. (Thu, 16 Nov 2006 15:13:00 GMT)
Please Exhale: New Method Detects Breath 'Fingerprint'
Swiss researchers led by R. Zenobi have developed a mass-spectrometric method to quickly and easily obtain a proper fingerprint of breath, including the quantitative detection of large, nonvolatile compounds. Breath analysis has some advantages for clinical diagnosis, for example it requires no puncture. (Thu, 16 Nov 2006 16:11:12 GMT)
Taking ''chips'' to the next level of gene hunting
Researchers at the Johns Hopkins'' High Throughput Biology Centre have invented two new gene "chip" technologies that can be used to help identify otherwise elusive disease-causing mutations in the 97 percent of the genome long believed to be "junk." (Thu, 16 Nov 2006 16:15:30 GMT)
Opinions: Letters to the Editor
As a former Daily staff writer, I understand that The Daily makes mistakes. Sometimes writing articles is tough, particularly when you have to write articles and know nothing about the subject matter. I imagine that me covering Bioinformatics was something like K-Fed covering election night results. (Thu, 16 Nov 2006 16:48:43 GMT)
Neanderthal Genome Sequencing Yields Surprising Results And Opens A New Door To Future Studies
The veil of mystery surrounding our extinct hominid cousins, the Neanderthals, has been at least partially lifted to reveal surprising results. Scientists with the U.S. Department of Energy's Lawrence Berkeley National Laboratory (Berkeley Lab) and the Joint Genome Institute (JGI) have sequenced genomic DNA from fossilized Neanderthal bones. (Thu, 16 Nov 2006 18:11:05 GMT)
U of M to expand its presence in Rochester
University of Minnesota President Robert Bruininks said on Thursday that the university will expand its presence here, including moving to a new temporary location and giving the campus its own chancellor. (Thu, 16 Nov 2006 19:01:34 GMT)
Genetics Influence Adolescent Language Problems
Specific language impairment (SLI) is a condition in which a child's language development is deficient despite showing normal development in all other areas. New research, published in Current Directions in Psychological Science, attempts to identify the cause behind this affliction. (Thu, 16 Nov 2006 19:11:43 GMT)
Applera Declares Dividend
Applera Corp. said Thursday it will pay a regular quarterly dividend of 4.25 cents per share on Applera Corporation - Applied Biosystems Group stock. (Thu, 16 Nov 2006 22:49:58 GMT)
DNAPrint Genomics Recommends Federal Source for Funding of DNA "Cold Case" Tests
DNAPrint Genomics, Inc. (OTCBB: DNAG) today announced that, in order to encourage the use of DNA testing in the solving of so-called "cold cases," the National Institute of Justice (NIJ), through its DNA grant program, provides funding to assist in the investigative and analysis process. (Fri, 17 Nov 2006 00:19:23 GMT)
New Products: Accelrys releases new imaging and bioinformatics platform
Accelrys Inc. announced the sixth generation of SciTegic Pipeline Pilot. ITLA Capital Corp., announced that its wholly-owned bank subsidiary, Imperial Capital Bank, has entered into a correspondent banking relationship with Wachovia Bank. (Fri, 17 Nov 2006 02:57:28 GMT)
CSU campuses show support for new master's program
An innovative master's degree soon will be offered at San Diego State and 15 other campuses in the California State University system after receiving strong support from the chancellor's office. (Fri, 17 Nov 2006 02:57:41 GMT)
CrossRef Extends Web Services
CrossRef, a reference linking network for scholarly publishing, has released an OAI-PMH (Open Archives Initiative Protocol for Metadata Harvesting) interface to its web services metadata distribution program. (Fri, 17 Nov 2006 05:16:45 GMT)
DNAPrint Genomics Recommends Federal Source for Funding of DNA "Cold Case" Tests
DNAPrint Genomics, Inc. (OTCBB: DNAG) todayannounced that, in order to encourage the use of DNA testing in the solvingof so-called 'cold cases,' the National Institute of Justice (NIJ), throughits DNA grant program, provides funding to assist in the investigative andanalysis process. (Fri, 17 Nov 2006 05:26:31 GMT)
Mayo Clinic: Gene expression profiling not quite perfected in predicting lung cancer prognosis
The accuracy of gene expression-based outcome prediction varies greatly among studies. Most studies lacked independent validation. Clinical outcome prediction between gene expression profiles and pathological features overlap significantly. (Fri, 17 Nov 2006 05:40:22 GMT)
U of M to expand in Rochester
ROCHESTER, Minn. — University of Minnesota President Robert Bruininks said Thursday the university will expand its presence in Rochester, including moving to a new temporary location and giving the campus its own chancellor. (Fri, 17 Nov 2006 06:01:34 GMT)
Gene Expression Profiling Not Quite Perfected in Predicting Lung Cancer Prognosis
While there have been significant advances in the use of gene expression profiling to assess a cancer prognosis, a Mayo Clinic review and analysis of existing lung cancer studies shows that this technology has not yet surpassed the accuracy of conventional methods used to assess survival in lung cancer patients. (Fri, 17 Nov 2006 06:30:19 GMT)
University Of Iowa Scientists Explore Function Of 'Junk DNA'
University of Iowa scientists have made a discovery that broadens understanding of a rapidly developing area of biology known as functional genomics and sheds more light on the mysterious, so-called "junk DNA" that makes up the majority of the human genome.The team, led by Beverly Davidson, Ph.D., a Roy J. [click link for full article] (Fri, 17 Nov 2006 08:08:47 GMT)
Gene Expression Profiling Not Quite Perfected in Predicting Lung Cancer Prognosis, Mayo Clinic Study Says
To: National Desk Contact: Amy Reyes of Mayo Clinic, 507-284-5005 or 507-284-2511 or newsbureau@mayo.edu ROCHESTER, Minn., Nov. 17 /U.S. (Fri, 17 Nov 2006 08:12:30 GMT)
U plans to expand Rochester campus
University of Minnesota President Robert Bruininks said Thursday that the university will expand its presence here, including moving to a new temporary location and giving the campus its own chancellor. (Fri, 17 Nov 2006 09:10:27 GMT)
Taking 'Chips' To The Next Level Of Gene Hunting
Researchers at the Johns Hopkins' High Throughput Biology Center have invented two new gene "chip" technologies that can be used to help identify otherwise elusive disease-causing mutations in the 97 percent of the genome long believed to be "junk." (Fri, 17 Nov 2006 11:10:42 GMT)
Unraveling Where Chimp And Human Brains Diverge
Six million years ago, chimpanzees and humans diverged from a common ancestor and evolved into unique species. Now UCLA scientists have identified a new way to pinpoint the genes that separate us from our closest living relative -- and make us uniquely human. (Fri, 17 Nov 2006 11:12:28 GMT)
Acacia Technologies Acquires Rights to Patents for Location Based Services (LBS) Technology
NEWPORT BEACH, Calif., BUSINESS WIRE -- Acacia Research Corporation (Nasdaq:ACTG) (Nasdaq:CBMX) announced today that Acacia Patent Acquisition Corporation, a wholly owned subsidiary that is part of the Acacia Technologies group, a leader in technology licensing, has acquired rights to patents relating to location based services (LBS) technology. (Fri, 17 Nov 2006 12:24:36 GMT)
Ocimum buys biz division of Dutch firm Isogen
Hyderabad-based Ocimum Biosolutions, provider of bioinformatics solutions and contract research, has acquired the bio-molecules synthesis business of Dutch firm Isogen Life Science for an undisclosed sum. (Fri, 17 Nov 2006 14:50:36 GMT)
Waters Corporation Introduces New Line Of Peptide Separation Columns
Waters Corporation has introduced new columns for peptide analysis and isolation based on its proprietary C18 BEH Technology particle platform (Fri, 17 Nov 2006 15:02:21 GMT)
Agilent Technologies Launches Life Science and Chemical Analysis Centers of Excellence in California, India and Europe
SANTA CLARA, Calif.----Agilent Technologies Inc. today launched a new product demonstration center at its Santa Clara, Calif., corporate headquarters, showcasing its life sciences and chemical analysis capabilities. (Fri, 17 Nov 2006 16:00:00 GMT)
Molecular Genetics Are Examined Inside 'Genomics and Genetics: From Molecular Details to Analysis and Techniques'
DUBLIN, Ireland----Research and Markets has announced the addition of Genomics and Genetics: From Molecular Details to Analysis and Techniques to their offering. (Fri, 17 Nov 2006 16:50:00 GMT)
American Cancer Society to Present Highest Honor to Katie Couric, Alice T. and William H. Goodwin Jr., Mary-Claire King
The American Cancer Society will present its highest honor, the Medal of Honor, to five Americans who have made outstanding contributions to the fight against cancer. This year's winners, who will receive their awards at the American Cancer Society's annual meeting in New York City, are: Katie Couric, Medal of Honor for Cancer Control; Alice T. and William H. (Fri, 17 Nov 2006 16:55:00 GMT)
Agilent opens demonstration center in Santa Clara
Agilent Technologies Inc. said Friday it launched a new product demonstration center that showcases the company's life science and chemical analysis capabilities. (Fri, 17 Nov 2006 17:13:50 GMT)
Money: It's More Than An Incentive According To University Of Minnesota Researcher
Why are some people more self-sufficient than others? Why are some people more willing to volunteer or help out than others? What makes some people seem stand-offish, while others move right in and help? Research conducted by Kathleen Vohs, assistant professor of marketing at the Carlson School of Management, University of Minnesota, demonstrates that money -- more specifically, people's exposure (Fri, 17 Nov 2006 19:11:37 GMT)
American Cancer Society to Present Highest Honor to Katie Couric, Alice T. And William H. Goodwin Jr., Mary-Claire King
NEW YORK, Nov. 17 /PRNewswire/ -- The American Cancer Society will present its highest honor, the Medal of Honor, to five Americans who have made outstanding contributions to the fight against cancer. (Fri, 17 Nov 2006 20:12:37 GMT)
UCSD Computer Scientist Wins Young Investigator Award, Research On Snake Venom Proteins Highlighted
Nuno Bandeira, a computer science and engineering Ph.D. candidate at UC San Diego's Jacobs School of Engineering has won the 2006 Human Proteome Organization's Young Investigator Award for work on snake venom proteins. [click link for full article] (Fri, 17 Nov 2006 21:07:57 GMT)
Analytica Anacon opens, experts assert India's potential in analytical instruments
India is an upcoming market of the future in analytical instruments, according to Dr. G Ramakrishna, president, Indian Analytical Instruments Association (IAIA) and director Asia Business Development, ThermoFisher Scientific. (Sat, 18 Nov 2006 02:52:52 GMT)
Pressured By Predators, Lizards See Rapid Shift In Natural Selection
Countering the widespread view of evolution as a process played out over the course of eons, evolutionary biologists have shown that natural selection can turn on a dime -- within months -- as a population's needs change. In a study of island lizards exposed to a new predator, the scientists found that natural selection dramatically changed direction over a very short time, within a single (Sat, 18 Nov 2006 15:11:23 GMT)
Taking 'Chips' To The Next Level Of Gene Hunting
Researchers at the Johns Hopkins' High Throughput Biology Center have invented two new gene "chip" technologies that can be used to help identify otherwise elusive disease-causing mutations in the 97 percent of the genome long believed to be "junk. [click link for full article] (Sat, 18 Nov 2006 18:08:15 GMT)
Community groups want bigger piece of pie from the university
Leticia Carranza, who was putting her son in a car seat for infants even though he had outgrown it, got a larger seat worth $40 for free. Jeff Walker, a UW-Madison scientist, got nearly $1 million to buy mass spectrometers to study proteins. (Sun, 19 Nov 2006 05:59:54 GMT)
DNA Analysis Could Boost Accuracy Of Thyroid Tests
By fine-tuning "fine-needle aspiration" biopsies with a super-fast genetic microarray technology, a team of surgeons from NewYork-Presbyterian Hospital/Weill Cornell Medical Center in New York City says they can greatly enhance the accuracy of these tests."For patients with worrisome thyroid nodules, this means better information on whether the nodule is malignant or benign. [click link for full (Sun, 19 Nov 2006 08:09:06 GMT)
Love him or loathe him, Hayworth unlikely to stay out of limelight long
After a stunning loss, J.D. Hayworth is gone. At least from the political scene. At least for now. But he is a larger-than-life presence who is unlikely to stay out of the spotlight for long. (Sun, 19 Nov 2006 08:25:42 GMT)
The Application of Microarray Technology to Neuropathology: Cutting Edge Tool With Clinical Diagnostics Potential or
By McShea, Andrew; Marlatt, Michael W; Lee, Hyo (Sun, 19 Nov 2006 09:11:47 GMT)
The Human Prion Protein Residue 129 Polymorphism Lies Within a Cluster of Epitopes for T Cell Recognition
By Isaacs, Jeremy D; Ingram, Rebecca J; Collinge, John; Altmann, Daniel M; Jackson, Graham S Abstract T cell immune responses to central nervous system-derived and other self-antigens are commonly described in both healthy and autoimmune individuals. (Sun, 19 Nov 2006 09:11:57 GMT)
Rosetta Genomics Nasdaq IPO shelved
The IPO could have been completed at a lower share price, but the company preferred not to do so. (Sun, 19 Nov 2006 10:16:12 GMT)
UI busy with several new honey bee studies
Honey bees probably would have been near the top of the list of species whose genes scientists wanted to map even if they weren't so sociable. They are, after all, the premier pollinating insect on the planet and have a hand in producing billions of dollars in U.S. food crops every year, University of Illinois entomology Professor Gene Robinson said recently. (Sun, 19 Nov 2006 16:55:53 GMT)
Researchers Unravel A Mystery About DNA
UCLA researchers in collaboration with researchers at Rutgers University have solved longstanding mysteries surrounding DNA transcription, the first step in carrying out instructions contained in our genes. (Sun, 19 Nov 2006 17:41:02 GMT)
Full description
Age-related macular degeneration (ARMD) is the leading cause of severe, irreversible vision loss for those over the age of fifty in the United States and in other developed countries. (Sun, 19 Nov 2006 19:22:41 GMT)
Ocimum Bio acquires Netherlands based Isogen Life Science
Ocimum Biosolutions, a leading provider of laboratory information management systems (LIMS), bioinformatics solutions, Microarrays and contract research based in Hyderabad, has acquired the BioMolecules synthesis business of Isogen Life Science based in Netherlands. (Mon, 20 Nov 2006 02:52:43 GMT)
New biomarker testing tech is changing drug discovery
There is a revolution afoot in drug development to improve productivity and increase the efficiency of bringing drug candidates through the clinical trials process. Biological markers -- or biomarkers -- are being used to develop early information about test results of drug candidates and directing those candidates toward the patients most likely to respond. (Mon, 20 Nov 2006 05:05:35 GMT)
Microarrays are Go!
A workhorse genetic testing tool called a microarray got a lot more respect recently. The dime-sized, not-inexpensive gene chip is as common as a test tube in many pharmaceutical laboratories. Yet, the gene activity data detected by microarrays have not been trusted by everyone in the scientific community nor fully accepted as a drug research method. (Mon, 20 Nov 2006 05:05:45 GMT)
Nutrigenomics -- Diet Of The Future?
It's the diet that promises to help you slim down and get healthy, with cues from your own DNA. (Mon, 20 Nov 2006 05:11:52 GMT)
Community groups want bigger piece of pie from the university
Leticia Carranza, who was putting her son in a car seat for infants even though he had outgrown it, got a larger seat worth $40 for free. Jeff Walker, a UW-Madison scientist, got nearly $1 million to buy mass spectrometers to study proteins. (Mon, 20 Nov 2006 05:15:34 GMT)
Top scientist quits job alleging lack of autonomy
Bhubaneswar, Nov 20 (IANS) Afsar Abbas, a scientist who three months ago was appointed the founding director of a top government research centre, has suddenly resigned from his post over what he says is lack of autonomy. An international conference, which was being organised by him and was scheduled for January 2007, also had to be cancelled due to his resignation. (Mon, 20 Nov 2006 07:22:37 GMT)
Despite Technical Hurdles, Potential to Transform Drug Discovery and Development to Drive Gene Expression Markets
The analysis of gene sequence and gene expression variations allows for the detection of defective genes and polymorphisms associated with specific diseases. These techniques provide the initial answers as to whether a potential therapeutic compound merits further evaluation and testing, making it of immense use to drug discovery and development. (Mon, 20 Nov 2006 08:00:00 GMT)
Top scientist quits job alleging lack of autonomy
By Jatindra Dash, Bhubaneswar, Nov 20: Afsar Abbas, a scientist who three months ago was appointed the founding director of a top government research centre, has suddenly resigned from his post over what he says is lack of autonomy. (Mon, 20 Nov 2006 08:33:29 GMT)
Illumina to Present at 18th Annual Piper Jaffray Health Care Conference
SAN DIEGO----Illumina, Inc. announced today that Jay Flatley, President and Chief Executive Officer, will present an overview of the Company's commercial and product development activity at the upcoming Piper Jaffray Health Care Conference in New York, NY. (Mon, 20 Nov 2006 11:00:00 GMT)
From bones, a woman's life unfolds
At first, all Sgt. Paul Dostie had were handfuls of bones -- fragile, gnawed-on human bones. There was very little he could tell from the animal-ravaged remains found in a shallow grave in the Inyo National Forest in May 2003. Dostie only knew the victim was a petite woman who wasn't dressed for the rugged Sierra Nevada, judging by her lacy blouse and flimsy jacket. (Mon, 20 Nov 2006 11:09:43 GMT)
Research Suggests Beta Agonists May Alter The Immune System
New research at Wake Forest University School of Medicine suggests that certain inhaled asthma medications -- as well as similar chemicals our bodies produce during times of high stress -- may worsen diseases such as asthma, heart failure and lupus that involve inflammation. (Mon, 20 Nov 2006 11:10:55 GMT)
Fighting Like A Girl Or Boy Determined By Gene In Fruit Flies
Fighting like a girl or fighting like a boy is hardwired into fruit fly neurons, according to a study in the November 19 Nature Neuroscience advance online publication by a research team from Harvard Medical School and the Institute of Molecular Pathology in Vienna. The results confirm that a gene known as "fruitless" is a key factor underlying sexual differences in behavior. (Mon, 20 Nov 2006 11:11:26 GMT)
ACS News Service Weekly PressPac -- Nov. 15, 2006
Here is the latest American Chemical Society (ACS) News Service Weekly press package (PressPac) with reports selected from 35 major peer-reviewed journals and Chemical & Engineering News. (Mon, 20 Nov 2006 14:10:32 GMT)
Ludwig Fund Donates $20 Million To University Of Chicago For Cancer Research
The Virginia & D.K. Ludwig Fund for Cancer Research, created by American billionaire Daniel K. Ludwig, today announced that it has donated $20 million to each of six leading cancer research institutions -- including the University of Chicago -- to create Ludwig Centers for cancer research. This $120 million donation will provide an immediate boost to cancer research. [click link for full article] (Mon, 20 Nov 2006 15:08:06 GMT)
NHGRI funds large-scale sequencing centers
BETHESDA, Md., Mon., Nov. 20, 2006 -- The National Human Genome Research Institute (NHGRI) today announced the results of the recent competition for support of its three large-scale sequencing centers, strengthening efforts to use the power of DNA sequencing to unlock the genomic secrets of human diseases. (Mon, 20 Nov 2006 15:25:51 GMT)
Sharing some, Keeping most: The Blue Cross for-profit conversion
Leticia Carranza, who was putting her son in a car seat for infants even though he had outgrown it, got a larger seat worth $40 for free. Jeff Walker, a UW-Madison scientist, got nearly $1 million to buy mass spectrometers to study proteins. (Mon, 20 Nov 2006 15:44:46 GMT)
Research and Markets: Roche and Affymetrix Were the First to Receive FDA Clearance for A Biochip-Based Molecular
DUBLIN, Ireland----Research and Markets has announced the addition of 2007 The Worldwide Biochip & Equipment Market to their offering. (Mon, 20 Nov 2006 15:50:00 GMT)
Agilent Technologies Announces New Technique for Rapid Analysis of Key Breast Milk Component
SANTA CLARA, Calif.----Agilent Technologies today announced a new technique developed by a team of University of California at Davis and Agilent scientists that enables rapid, detailed analysis of the composition of a group of bioactive molecules in breast milk. (Mon, 20 Nov 2006 16:00:00 GMT)
CXR Biosciences Ltd. Licenses the Rosetta Resolver Gene Expression Data Analysis System from Rosetta Biosoftware
SEATTLE & DUNDEE, Scotland----Rosetta Biosoftware announced today that CXR Biosciences Ltd. licensed the Rosetta Resolver® system to investigate mechanisms of drug toxicity. CXR Biosciences plans to use the statistical analysis tools in the Resolver system to generate high-quality data to support its toxicological research using transcriptional profiling. (Mon, 20 Nov 2006 16:00:00 GMT)
Agilent Technologies Launches Life Science And Chemical Analysis Centers Of Excellence In California, India And Europe
Agilent Technologies Inc. launched a new product demonstration center at its Santa Clara, Calif., corporate headquarters, showcasing its life sciences and chemical analysis capabilities (Mon, 20 Nov 2006 16:17:05 GMT)
Texas A&M genetically modifies cotton to make it edible
A chemical called gossypol makes cottonseed inedible for humans, though some of it is used in feed for cattle, which are less affected by the toxin. (Mon, 20 Nov 2006 16:42:14 GMT)
University of Leuven Selects GenoLogics Solution for Lab and Data Management
Vancouver, BC, November 20, 2006--(T-Net)--GenoLogics Life Sciences Software, a leading developer of lab and data management software solutions, today announced the ProMeta Interfaculty Centre for Proteomics and Metabolomics at Belgium’s University of Leuven has selected GenoLogics’ Proteus™ as the lab and scientific data management solution for its proteomics and metabolomics research. (Mon, 20 Nov 2006 17:01:01 GMT)
Modified cottonseed be a source of food for humans
WASHINGTON (AP) -- Cotton, for thousands of years one of the most important crops for clothing and shelter, might also become a source of food. (Mon, 20 Nov 2006 17:20:06 GMT)
Georgia Tech center to foster Cell processor
Georgia Tech's College of Computing has partnered with Sony, Toshiba and IBM to create a "center of competence" focused on fostering the Cell microprocessor technology in such applications as bioinformatics, scientific computing, finance and entertainment. (Mon, 20 Nov 2006 17:29:53 GMT)
Genetically Modified Cottonseed May Provide Human Food
Washington (AP) - For thousands of years, cotton has been one of the most important crops for clothing and shelter. Now, it might also become a source of food. (Mon, 20 Nov 2006 17:39:41 GMT)
Cancer Research Technology and The University of Manchester Announce Clinical Pharmacology Collaboration in Oncology
London, UK; Manchester, UK, 20 November 2006 - Cancer Research Technology Limited (CRT), the oncology-focused development and commercialisation company, and The University of Manchester have entered into an agreement with AstraZeneca to establish a clinical pharmacology biomarker research and discovery collaboration. (Mon, 20 Nov 2006 17:52:42 GMT)
Scientists modify cottonseed to make it edible
A chemical called gossypol makes cottonseed inedible for humans, though some of it is used in feed for cattle, which are less affected by the toxin. (Mon, 20 Nov 2006 19:36:40 GMT)
Feds hand Broad Institute $200M genomics grant
The Broad Institute in Cambridge reports it has landed an award of almost $200 million from the National Human Genome Research Institute (NHGRI) in support of large-scale DNA sequencing for biomedicine. (Mon, 20 Nov 2006 21:01:24 GMT)
Advance helps explain stem cell behavior
CORVALLIS, Ore. -- Biochemists at Oregon State University have developed a new method to identify the "DNA-binding transcription factors" that help steer stem cells into forming the wide variety of cells that ultimately make up all the organs and parts of a living vertebrate animal. (Mon, 20 Nov 2006 22:10:56 GMT)
Modified cottonseed may be used for food
Cotton, for thousands of years one of the most important crops for clothing and shelter, might also become a source of food. A chemical called gossypol makes cottonseed inedible for humans, though some of it is used in feed for cattle, which are less affected by the toxin. Now, researchers at Texas A&M University have genetically modified cotton to produce seeds with little or no gossypol. (Tue, 21 Nov 2006 01:16:25 GMT)
Modified Cottonseed May Be Used for Food
WASHINGTON -- Cotton, for thousands of years one of the most important crops for clothing and shelter, might also become a source of food. A chemical called gossypol makes cottonseed inedible for humans, though some of it is used in feed for cattle, which are less affected by the toxin. (Tue, 21 Nov 2006 01:37:51 GMT)
Modified cottonseed may be used for food
Cotton, for thousands of years one of the most important crops for clothing and shelter, might also become a source of food. A chemical called gossypol makes cottonseed inedible for humans, though some of it is used in feed for cattle, which are less affected by the toxin. Now, researchers at Texas A&M University have genetically modified cotton to produce seeds with little or no gossypol. (Tue, 21 Nov 2006 01:38:24 GMT)
Researchers genetically alter plants to make cottonseed that is edible
Cotton, for thousands of years one of the most important crops for clothing and shelter, may become a source of food. (Tue, 21 Nov 2006 06:19:55 GMT)
Indian researcher among America's top scholars
Sudhir Kumar, director of the Center for Evolutionary Functional Genomics in the Biodesign Institute at Arizona State University, recently joined the elite ranks of most-cited researchers, having the fourth-highest number of citations in the field of computer science over the last decade. (Tue, 21 Nov 2006 06:44:44 GMT)
Sharing some, Keeping most: The Blue Cross for-profit conversion
Leticia Carranza, who was putting her son in a car seat for infants even though he had outgrown it, got a larger seat worth $40 for free. Jeff Walker, a UW-Madison scientist, got nearly $1 million to buy mass spectrometers to study proteins. (Tue, 21 Nov 2006 07:00:55 GMT)
UW technology transfer extends reach
Marshfield Clinic said Monday that it will become the first organization outside of the state's public university system to use the system's technology transfer expertise to commercialize the work of researchers. (Tue, 21 Nov 2006 07:33:47 GMT)
Toxin-free cotton may fulfil nutritional needs of billions of poor
London, Nov. 21 (ANI): US researchers have genetically engineered cotton plants that produce toxin-free seeds, potentially unlocking enough nutritional content to feed half a billion people worldwide each year. Lead author Keerti Rathore from the Institute for Plant Genomics and Biotechnology at Texas A and M University in College Station, says that every kilogram of fibre produced from cotton (Tue, 21 Nov 2006 08:03:51 GMT)
$200M Boosts Cancer Research
A Harvard-affiliated research center has received close to $200 million for research geared towards understanding cancer and other human diseases. The Broad Institute, a Harvard-MIT collaboration whose mission is to apply emerging genomics research and technology towards medical application, was awarded a grant yesterday from the National Institute of Health’s National Human Genome Research (Tue, 21 Nov 2006 08:35:09 GMT)
Clinic, UW to collaborate on research, development
The opportunities for medical discoveries to rapidly become life-saving tools took a leap forward Monday as officials from the Marshfield Clinic and the University of Wisconsin System met to sign a collaborative agreement. (Tue, 21 Nov 2006 09:48:07 GMT)
Specialist members wanted
The Committee on Toxicity of Chemicals in Food, Consumer Products and the Environment (COT) is looking for people to fill vacancies for specialist positions that have arisen on the committee. (Tue, 21 Nov 2006 09:59:01 GMT)
Acacia Technologies Licenses Image Resolution Enhancement Technology to Dell
NEWPORT BEACH, Calif.----Acacia Research Corporation announced today that IP Innovation, LLC, a wholly owned subsidiary that is a part of the Acacia Technologies group, has entered into a License Agreement with Dell Inc. covering patents that apply to Image Resolution Enhancement Technology. (Tue, 21 Nov 2006 11:01:00 GMT)
Gene Expression Profiling Not Quite Perfected In Predicting Lung Cancer Prognosis
While there have been significant advances in the use of gene expression profiling to assess a cancer prognosis, a Mayo Clinic review and analysis of existing lung cancer studies shows that this technology has not yet surpassed the accuracy of conventional methods used to assess survival in lung cancer patients. (Tue, 21 Nov 2006 11:10:53 GMT)
Scientists Explore Function Of 'Junk DNA'
University of Iowa scientists have made a discovery that broadens understanding of a rapidly developing area of biology known as functional genomics and sheds more light on the mysterious, so-called "junk DNA" that makes up the majority of the human genome. (Tue, 21 Nov 2006 11:12:36 GMT)
Get master's at Stanford, without going to the Farm
Some of Stanford University's most diligent students are never in class -- or even in the same time zone. These foreign students, earning a master's degree in engineering through a program available entirely online, concede that they miss the sports, sunshine and the easy camaraderie of the Cardinal. (Tue, 21 Nov 2006 11:20:31 GMT)
DNAPrint Announces German Business Partner's First Human Study of Product to Prevent Migraines
DNAPrint Genomics, Inc. today announced that its German business partner, Biofrontera AG, in which the Company owns an approximate 10% stake, has received authorization to begin its first human study of its BF-1 drug, which is intended to prevent migraine headaches. (Tue, 21 Nov 2006 12:00:00 GMT)
Acacia Technologies Acquires Rights to Patents Relating to Document Generation Technology
NEWPORT BEACH, Calif., BUSINESS WIRE -- Acacia Research Corporation (Nasdaq:ACTG) (Nasdaq:CBMX) announced today that Acacia Patent Acquisition Corporation, a wholly owned subsidiary that is part of the Acacia Technologies group, a leader in technology licensing, has acquired rights to patents relating to document generation technology. (Tue, 21 Nov 2006 12:24:56 GMT)
Acacia Technologies Licenses Image Resolution Enhancement Technology to Dell
NEWPORT BEACH, Calif., (Tue, 21 Nov 2006 12:25:06 GMT)
Advance helps explain stem cell behavior
Biochemists at Oregon State University have developed a new method to identify the "DNA-binding transcription factors" that help steer stem cells into forming the wide variety of cells that ultimately make up all the organs and parts of a living vertebrate animal. (Tue, 21 Nov 2006 13:09:19 GMT)
Researchers look to ease process of developing drugs
Researchers at Boston University's Structural Bioinformatics Lab are working with Mercury Computer Systems to develop a system that will make it easier for pharmaceutical companies to develop new drugs. Currently, drug researchers studying new drugs must find a specific molecule that binds to a target protein. (Tue, 21 Nov 2006 13:53:03 GMT)
Previous 1 2 3 4 5 Next